Abstract:
INTRODUCTION:We investigated the relationship of insight with executive functions and symptoms in a group of stabilised inpatients with schizophrenia. METHODS:Executive functions using an extensive battery constituted of several tests as well as psychopathology were assessed in 38 inpatients with a DSM-IV diagnosis of schizophrenia. Insight was assessed with the Scale to assess Unawareness of Mental Disorder (SUMD). RESULTS:A principal component analysis of the insight dimensions revealed a three-factor model which accounted for 98% of the variance. Of particular interest is the finding that a composite factor that accounted for 74% of the variance covered insight dimensions that represent a higher degree of insight (awareness of mental disorder, its social consequences, and attribution of symptoms). Only an association between letter fluency and this composite factor was found, which was weakly mediated by depressive symptoms. A stepwise multiple regression analysis revealed a relationship between antipsychotic dose and awareness of medication effect. No association of illness duration and insight was found. CONCLUSIONS:The findings of partial association between dimensions of insight and measures of executive function supports the growing evidence that insight is a multidimensional phenomenon. Accordingly, they emphasise that in the framework of therapeutic interventions, enhancement of higher levels of insight needs to take into account that patients suffering from schizophrenia have differential impairment in insight dimensions.
journal_name
Cogn Neuropsychiatryjournal_title
Cognitive neuropsychiatryauthors
Simon AE,Berger GE,Giacomini V,Ferrero F,Mohr Sdoi
10.1080/13546800444000308subject
Has Abstractpub_date
2006-09-01 00:00:00pages
437-51issue
5eissn
1354-6805issn
1464-0619pii
769903630journal_volume
11pub_type
杂志文章abstract:INTRODUCTION:Cognitive neuropsychiatry has had much success in providing theoretical models for the causal origins of many delusional beliefs. Recently, it has been suggested that some anorexia nervosa patients' beliefs about their own body size should be considered delusions. As such, it seems high time the methods of...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2017.1401531
更新日期:2017-11-01 00:00:00
abstract:INTRODUCTION:In a previous study (Silverstein, Bakshi, Chapman, & Nowlis, 1998a, Cognitive Neuropsychiatry) we demonstrated that while schizophrenia patients showed similar learning curves as nonpatient controls when determining whether a configural pattern of elements has been seen before or not, they did not demonstr...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800444000029
更新日期:2005-06-01 00:00:00
abstract::Introduction: Cognitive impairment is related to an increase in cardiovascular risk (CVR) in the general population. However, in severe mental disorder (SMD), the evidence is less consistent. Few studies have evaluated the relationship between cognition and vascular burden in SMD. This study determines the relationshi...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1676709
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Individuals with schizophrenia consistently show impairments in social cognition (SC). SC has become a potential treatment target due to its association with functional outcomes. An alternative method of assessment is to administer an observer-based scale incorporating an informant's "first hand" impressio...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2014.999915
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Category fluency is associated with speed-, executive- and semantic impairments in schizphrenia. It has traditionally been linked to negative symptoms, whereas the relation to positive symptoms is mixed. Associations to the consensus negative, positive and disorganisation factors have not been analysed bef...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1080/13546805.2017.1418306
更新日期:2018-01-01 00:00:00
abstract::In order to ask whether autism is associated with difficulty in self-monitoring we gave a group of children and adolescents with autism a task in which they themselves had to remember whether they or another person had performed certain actions. In our first experiment, three groups of participants had to recall wheth...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468099395855
更新日期:1999-11-01 00:00:00
abstract:INTRODUCTION:Functional Cognitive Disorder (FCD) is poorly understood. We sought to better characterise FCD in order to inform future diagnostic criteria and evidence based treatments. Additionally, we compared FCD patients with and without co-morbid depression, including their neuropsychological profiles, to determine...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1590190
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION:We have previously reported that people with schizophrenia and formal thought disorder (FTD) were disproportionately impaired in recalling sentences verbatim and in judging their plausibility. We proposed that these deficits were due to impairment in integrating higher-order semantic information to constru...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2013.870069
更新日期:2014-01-01 00:00:00
abstract::Numerous studies have suggested, via the interpretation of the negative priming effect as a measure of cognitive inhibition, that schizotypal subjects are less able to inhibit irrelevant distracting information. Recent research has revealed, however, that negative priming effects can be caused by two quite different p...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468097396423
更新日期:1997-02-01 00:00:00
abstract:INTRODUCTION:Studies comparing IQ in Offspring of Bipolar Parents (OBP) with Offspring of Healthy Controls (OHC) have reported conflicting findings. They have included OBP with mental health/neurodevelopmental disorders and/or pharmacological treatment which could affect results. This UK study aimed to assess IQ in OBP...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2016.1259103
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:There is evidence that schizophrenics have an abnormal corpus callosum and an abnormal pattern of cerebral asymmetries. We investigated whether there are corresponding functional abnormalities in interhemispheric transfer (IT) and laterality effects. METHODS:Medicated schizophrenic patients and matched co...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800143000195
更新日期:2002-05-01 00:00:00
abstract:INTRODUCTION:Visual scanning is widely reported to be abnormal in schizophrenia. The majority of eye movement studies in schizophrenic patients have used pictures of a face in isolation in free viewings. This study was designed to examine whether attentional control, through instructions, modulates the visuomotor behav...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2012.683245
更新日期:2013-05-01 00:00:00
abstract::Introduction: Cognitive impairments are common in both Autism Spectrum Disorders (ASD) and schizophrenia, but it is unclear whether the pattern of difficulties is similar or different in the two disorders. This cross-sectional and longitudinal study compared the neuropsychological functioning in adolescents with ASD w...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2020.1713736
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:Little is known about the relationship between cognitive dysfunction and functional disability in alcohol dependence with comorbid affective disorders. We investigated the neuropsychology of alcohol dependence in detoxified adults with and without affective comorbidity and examined the factors associated w...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2015.1014031
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Capgras syndrome is characterised by the belief that a significant other has been replaced by an identical-looking impostor. These patients have no difficulties with visual recognition but fail to show a skin conductance response (SCR) to the objects of the delusion. A case of Capgras delusion (YY), specif...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800600892183
更新日期:2007-05-01 00:00:00
abstract::INTRODUCTION. Ample evidence already shows that theory of mind (ToM) is impaired in people with schizophrenia. Our aim was to critically review this literature. METHOD. We completed a selected review of the research literature on ToM in schizophrenia. RESULTS. Gaps in ToM research were identified. A specific relations...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,评审
doi:10.1080/13546805.2011.561576
更新日期:2011-11-01 00:00:00
abstract:INTRODUCTION:Theory-of-mind (ToM) refers to the ability to understand and predict the behaviour of others based on their mental states. Research from brain imaging and lesion studies indicate that the frontal lobes are both involved and necessary to understand mental states. METHODS:A total of 13 people with Parkinson...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800244000292
更新日期:2003-08-01 00:00:00
abstract:INTRODUCTION:Patients with schizophrenia show impairments in working-memory and visual-spatial processing, but little is known about the dynamic interplay between the two. To provide insight into this important question, we examined the effect of positive and negative symptom expressions in healthy adults on perceptual...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2016.1206873
更新日期:2016-09-01 00:00:00
abstract::The psychopathological basis of delusions in schizophrenia is poorly understood. The most enduring of several early theories has suggested a causal link with formal thought disorder, whereas recent approaches have proposed relationships with a variety of cognitive abnormalities. The correlations of delusions with othe...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468096396451
更新日期:1996-11-01 00:00:00
abstract:INTRODUCTION:Although important to cognitive neuropsychiatry and theories of delusions, Capgras delusion has largely been reported in single case studies. Bell et al. [2017. Uncovering Capgras delusion using a large scale medical records database. British Journal of Psychiatry Open, 3(4), 179-185] previously deployed c...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1584098
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION:A sample of everyday difficulties was collected, encompassing errors and unusual experiences participants had encountered when recognising their own faces in everyday life, with the aim of characterising similarities and differences between the reported difficulties and the major forms of self-recognition ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800344000075
更新日期:2004-08-01 00:00:00
abstract:INTRODUCTION:Memory for public and autobiographical events was investigated in people diagnosed with depression, schizophrenia, and a group of healthy controls. The aim was to determine whether the overgeneral memory effect emerged in clinical conditions other than depression and in memory domains other than autobiogra...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800601066142
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION:It has been suggested that the positive symptoms of acute schizophrenia are a consequence of a disruption of the process that produces latent inhibition (slower acquisition of conditioned responding after preexposure to the conditioned stimulus) and that this effect can be modelled by pro- and antipsychoti...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,评审
doi:10.1080/13546805.2012.667202
更新日期:2012-11-01 00:00:00
abstract::Self-recognition and self-awareness are processes fundamental to human development. This report describes the case of an 80-year-old woman who demonstrated the ''mirror sign'', an inability to recognise the reflection of oneself in a mirror. An attempt has been made to provide a cognitive neuropsychological explanatio...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468096396613
更新日期:1996-05-01 00:00:00
abstract:INTRODUCTION:There is substantial evidence that patients with schizophrenia present with impaired Theory of Mind (ToM). Whereas previous studies have focused on general ToM abilities, the present study is aimed at testing the underlying behavioural and neurocognitive mechanisms of the impaired integration of affective ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800802490034
更新日期:2008-11-01 00:00:00
abstract:INTRODUCTION:Cognitive impairment is a pervasive feature of schizophrenia, and is a major determinant of the functional disability that is characteristic of the disorder. However, research investigating whether patients with schizophrenia show a deficit awareness remains unclear. The present study aimed to replicate an...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2014.909311
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Recent reports of lexical-semantic deficits in patients with schizophrenia (Laws, Al-Uzri, & Mortimer, 2000; Laws, McKenna, & Kondel, 1998) suggest that younger patients have problems accessing intact memories and older patients show apparent "loss" of the lexical-semantic memory representations themselves...
journal_title:Cognitive neuropsychiatry
pub_type: 临床试验,杂志文章
doi:10.1080/13546800444000137
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Substance abuse is highly prevalent in schizophrenia and it has been associated with negative consequences on the course of the pathology. Regarding cognition, the prevailing literature has produced mixed results. Some groups have reported greater cognitive impairments in dual diagnosis schizophrenia, while ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800802264330
更新日期:2008-07-01 00:00:00
abstract:INTRODUCTION:Research on empathy has a long tradition in clinical research, as deficits in empathy have been found in many mental disorders. Over decades, a large amount of measures for empathy have been developed, but in many cases these have not been analysed with respect to validity. Therefore, this paper aims to re...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2014.991781
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:We report a novel delusion, primarily persecutory in form, in which the patient believes that he is being filmed, and that the films are being broadcast for the entertainment of others. METHODS:We describe a series of patients who presented with a delusional system according to which they were the subject...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2012.666113
更新日期:2012-11-01 00:00:00