An evaluation of potentially suitable fixatives for immunoperoxidase staining of estrogen receptors in imprints and frozen sections of breast carcinoma.

abstract：:Malignant gastrointestinal neuroectodermal tumour (GNET) is a recently characterised rare and aggressive tumour that typically arises in association with the small intestine of adults. We present a novel case of this entity and expand the spectrum of its reported morphological features. The patient was a 5-year-old fe...

journal_title：Pathology

authors： Allanson BM,Weber MA,Jackett LA,Chan C,Lau L,Ziegler DS,Warby M,Mayoh C,Cowley MJ,Tucker KM,Long GV,Maher A,Anazodo A,Scolyer RA

更新日期：2018-10-01 00:00:00

abstract：:In 2004, the diagnosis of established human immunodeficiency virus (HIV) infection can be made with close to 100% assurity. The extraordinarily engineered performances of HIV-screening assays are unprecedented. The well-established confirmatory tests performed by well-versed laboratories using criteria that are well u...

journal_title：Pathology

authors： Dax EM,Arnott A

更新日期：2004-12-01 00:00:00

abstract：:Histopathologists are encountering intra-lobular epithelial proliferations more frequently in core biopsies taken from lesions identified in mammographic breast screening programmes. In particular, columnar cell lesions are increasingly being seen in core biopsies taken for the histological assessment of mammographica...

journal_title：Pathology

authors： Pinder SE,Provenzano E,Reis-Filho JS

更新日期：2007-04-01 00:00:00

abstract：AIM:To determine whether the common respiratory pathogen, Chlamydia pneumoniae, was associated with atherosclerotic plaques in Australian subjects. METHODS:A total of 29 coronary atherosclerotic lesions and 18 normal coronary arterial samples were tested for the presence of C. pneumoniae by PCR and immunofluorescence ...

journal_title：Pathology

authors： Cochrane M,Kalle WH,Roffey P,Moriarty HT

更新日期：2002-06-01 00:00:00

abstract：:Appropriate investigation of a patient with suspected von Willebrand's disease (VWD) involves a clinical assessment of the patient followed by laboratory testing. A variety of laboratory assays may be performed, not necessarily restricted to an assessment of von Willebrand factor (VWF). Due to the limitations of each ...

journal_title：Pathology

authors： Favaloro EJ,Koutts J

更新日期：1997-11-01 00:00:00

abstract：:The recent upsurge in the association of congenital neurological disorders and infection by the Zika virus (ZIKV) has resulted in increased research focus on the biology of this flavivirus. Studies in animal models indicate that ZIKV can breach the placental barrier and selectively infect and deplete neuroprogenitor c...

journal_title：Pathology

authors： Gharbaran R,Somenarain L

更新日期：2017-12-01 00:00:00

abstract：:The dense fine speckled (DFS) pattern is an antinuclear antibody (ANA) pattern that has recently become of interest. This particular pattern has not been associated with systemic autoimmune rheumatic disorders (SARD) but has been associated with other inflammatory conditions such as interstitial nephritis, autoimmune ...

journal_title：Pathology

authors： Broadfoot A,Sivertsen T,Baumgart K

更新日期：2016-04-01 00:00:00

abstract：:In the 20 years that cardiac troponin testing has been available in clinical laboratories, the biomarker has revolutionised testing of patients with acute coronary syndromes. Cardiac troponin I and T testing has become the cornerstone for diagnosis of myocardial infarction and is useful for risk assessment and managem...

journal_title：Pathology

authors： Christenson RH,Phillips D

更新日期：2011-04-01 00:00:00

abstract：:A 59 yr old male presented with abdominal pain and jaundice. CT scan showed a tumor in the pancreas with secondaries in the liver, peri-pancreatic lymph nodes, vertebral bone marrow and subcutaneous tissue of the neck together with a cervical lymph node. The patient died after 2 wks and autopsy revealed complete repla...

journal_title：Pathology

authors： Chetty R,Clark SP,Pitson GA

更新日期：1993-07-01 00:00:00

abstract：:Recently, both the World Health Organization/International Agency for Research on Cancer (WHO/IARC) and the American Joint Committee on Cancer (AJCC) have classified oropharyngeal squamous cell carcinoma (OPSCC) on the basis of HPV status. For this purpose, the WHO/IARC recommended direct molecular HPV testing. In pra...

journal_title：Pathology

authors： Veyer D,Wack M,Grard O,Bonfils P,Hans S,Bélec L,Badoual C,Péré H

更新日期：2019-06-01 00:00:00

abstract：:Papillary proliferations of the endometrium (PPEs) are uncommon lesions that are often associated with endometrial polyps. PPEs occasionally precede or co-exist with atypical endometrial hyperplasia or adenocarcinoma, but their pathogenesis and relationship to endometrial neoplasia is uncertain. In the present study 1...

journal_title：Pathology

authors： Stewart CJR,Bigby S,Giardina T,Grieu-Iacopetta F,Amanuel B

更新日期：2018-04-01 00:00:00

abstract：:Statistical methods have been used to determine an optimal approach to the definition of the reference range for CD4 ("helper") and CD8 ("suppressor/cytotoxic") T cell numbers and the CD4/CD8 ratio in the peripheral blood. A graphical presentation of the absolute values for CD4 and CD8 for 85 healthy blood donors show...

journal_title：Pathology

authors： Zachar V,Mikulecky M,Mayer V,Mackay I,Frazer I

更新日期：1988-10-01 00:00:00

abstract：:About 10% of gastric carcinomas are associated with Epstein-Barr virus (EBV), which are defined as EBV-associated gastric carcinomas (EBVaGCs). EBVaGCs are usually accompanied by massive lymphocytes infiltration, among which CD8+ T cells are predominant. To date, the apoptosis of the infiltrating CD8+ T cells in EBVaG...

journal_title：Pathology

authors： Tang F,Chen JN,Zhang NN,Gong LP,Jiang Y,Feng ZY,Xiao L,Li HG,Du H,Wu B,Shao CK

更新日期：2018-10-01 00:00:00

abstract：AIMS:Only a small number of mesenchymal tumours have been previously evaluated for hTERT expression. We hypothesised that hTERT expression would be frequently present in sarcomas, but not in benign tumours. METHODS:Sections from 143 bone/soft tissue tumours were immunostained for hTERT (44F12, 1:20; Novocastra) using ...

journal_title：Pathology

authors： Patel RM,Folpe AL

更新日期：2009-01-01 00:00:00

abstract：:Although most carcinomas of the bladder occur de novo, some vesical lesions progress to malignancy over time. These lesions appear morphologically benign, but often harbour genetic changes that signify their malignant potential. Despite their benign appearance, accurate identification is important given that these pat...

journal_title：Pathology

authors： Samaratunga H,Martignoni G,Egevad L,Delahunt B

更新日期：2013-04-01 00:00:00

abstract：:E-cadherin mediated intercellular adhesion is regulated by a family of cytoplasmic proteins that include alpha-, beta- and gamma-catenin and p120cas. Changes in expression of E-cadherin are believed to be an early event in melanoma development. Recent studies have also drawn attention to the over-expression of beta-ca...

journal_title：Pathology

authors： Zhang XD,Hersey P

更新日期：1999-08-01 00:00:00

abstract：:Assessment of the risk of lymph node invasion and tumour recurrence is critical to determine whether additional surgery is required in patients with endoscopically-removed pT1 colorectal cancer (CRC). A reproducible assessment of this risk of recurrence based on histopathological parameters is crucial for relevant the...

journal_title：Pathology

authors： Barel F,Auffret A,Cariou M,Kermarrec T,Samaison L,Bourhis A,Badic B,Jézéquel J,Cholet F,Bail JP,Marcorelles P,Nousbaum JB,Robaszkiewicz M,Doucet L,Uguen A

更新日期：2019-01-01 00:00:00

abstract：AIMS:CD151 belongs to the group of tetraspanins and is aberrantly expressed in different tumours and differential expression has been associated with prognosis. The aim of this study was to clarify the relationship of CD151 expression with tumour phenotype and clinical outcome in bladder cancer. METHODS:A bladder canc...

journal_title：Pathology

authors： Minner S,De Silva C,Rink M,Dahlem R,Chun F,Fisch M,Höppner W,Wagner W,Bokemeyer C,Terracciano L,Simon R,Sauter G,Wilczak W

更新日期：2012-08-01 00:00:00

abstract：:A fatal case of multiple sulfatase deficiency in a 10-year-old girl is reported. In this rare disease, which is inherited as an autosomal recessive, features of metachromatic leukodystrophy and of mucopolysaccharidoses occur together. The white matter suffers progressive destruction with sulfatides accumulating in mac...

journal_title：Pathology

authors： Kepes JJ,Berry A 3rd,Zacharias DL

更新日期：1988-07-01 00:00:00

abstract：:Seven cases of lower respiratory tract infection due to Corynebacterium pseudodiphtheriticum are described. Lower respiratory tract infections with C. pseudodiphtheriticum in immunocompetent patients are usually associated with pre-existing chronic pulmonary disease, and are sometimes associated with endotracheal intu...

journal_title：Pathology

authors： Freeman JD,Smith HJ,Haines HG,Hellyar AG

更新日期：1994-07-01 00:00:00

abstract：AIMS:We aimed to evaluate the effects of caffeic acid phenethyl ester (CAPE) on lithium (Li)-induced lung toxicity. METHODS:Twenty-two adult male Wistar albino rats weighing between 280 and 300 g were used. The rats were randomly divided into three groups: control, Li and Li+CAPE groups. Li and CAPE were co-administer...

journal_title：Pathology

authors： Sahin O,Sulak O,Yavuz Y,Uz E,Eren I,Ramazan Yilmaz H,Malas MA,Altuntas I,Songur A

更新日期：2006-02-01 00:00:00

abstract：AIMS:Whereas most caspases play roles in apoptosis and/or inflammation, caspase-14 plays a main role in epithelial differentiation. In cancers, expression of caspase-14 is frequently altered and is associated with some clinicopathological characteristics, suggesting caspase-14 might contribute to the pathogenesis of ca...

journal_title：Pathology

authors： Yoo NJ,Soung YH,Lee SH,Jeong EG,Lee SH

更新日期：2007-06-01 00:00:00

abstract：:A review of the morphological and metabolic interactions between hepatocytes, the various sinusoidal cells and sinusoidal blood is presented. This field of investigation is rapidly expanding, with widespread implications in the regulation of physiological processes and diseases in the liver and other organs. Although ...

journal_title：Pathology

authors： Fraser R,Day WA,Fernando NS

更新日期：1986-01-01 00:00:00

abstract：:An epidemiological study of childhood cancer in New Zealand identified 409 children aged 0 to 14 years with malignant neoplasms newly diagnosed between 1990 and 1993 inclusive. The original microscopic material on which the diagnoses were based was reviewed in 398 cases and the neoplasms were allocated into the 12 maj...

journal_title：Pathology

authors： Becroft DM,Dockerty JD,Berkeley BB,Chan YF,Lewis ME,Skeen JE,Synek BJ,Teague LR

更新日期：1999-05-01 00:00:00

abstract：:Human glomerular basement membrane (GBM) emulsified in Freund's complete adjuvant was injected into 16 Holtzman rats. Eleven (69%) of them subsequently developed glomerulonephritis. This disease was characterized by glomerular changes which included focal lobular hypercellularity due to localized hyperplasia of intrac...

journal_title：Pathology

authors： McCausland IP,Herdson PB,Gavin JB

更新日期：1976-04-01 00:00:00

abstract：:The early and late effects of wound healing on tumour development at a distant site were evaluated morphologically in an experimental model of colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH). Random bred male Wistar rats were given subcutaneous injections of DMH (20 mg/kg) or saline, once a week, for eight...

journal_title：Pathology

authors： Sequeira JL,Kobayasi SS,Rodrigues MA

更新日期：2000-11-01 00:00:00

abstract：:Thirty-one patients aged over 60 yrs and with lupus anticoagulant (LA) were reviewed for their drug intake. Twenty-three (73%) were taking cinchona alkaloids, 10 (32%) quinine for night cramps, 11 (35%) quinidine for cardiac arrhythmia and 2 (6%) were taking both. These frequencies of drugs usage differed significantl...

journal_title：Pathology

authors： Bird MR,O'Neill AI,Buchanan RR,Ibrahim KM,Des Parkin J

更新日期：1995-04-01 00:00:00

abstract：AIM:The purpose of this study was to elucidate the clonality of fibrous dysplasia based on X-chromosome inactivation mosaicism and polymorphism in female somatic cells at the phosphoglycerate kinase (PGK) and androgen receptor (AR) loci using microdissection technology. MATERIALS AND METHODS:Nine patients with fibrous...

journal_title：Pathology

authors： Gong L,Zhang W,Su Q

更新日期：2008-06-01 00:00:00

abstract：:Soft tissue tumours are relatively rare, but are diagnostically challenging as they comprise a large spectrum of diagnostic entities. Substantial advances have been made in recent years in identifying the underlying recurrent chromosomal and genomic alterations in a significant subset of soft tissue tumours, and this ...

journal_title：Pathology

authors： Schaefer IM,Fletcher CDM

更新日期：2018-01-01 00:00:00

abstract：:A survey conducted by the Australian Association of Clinical Biochemists Porphyrin Working Party on urinary porphobilinogen screening showed good sensitivity (75-97.5%). This is contrary to reports in the literature and to our own observations. We therefore assessed a widely used screening method (Watson-Schwartz) and...

journal_title：Pathology

authors： Buttery JE,Carrera AM,Pannall PR

更新日期：1990-10-01 00:00:00