Clonal status of fibrous dysplasia.

abstract：:Eccrine syringofibroadenoma is a rare benign tumor of the skin arising from the acrosyringeal portion of the eccrine duct. The tumor was first described by Mascaro in 1963, and since then only 8 case reports in 6 publications have been documented. This lesion is likely to be misdiagnosed both clinically and histologic...

journal_title：Pathology

authors： Billson VR,Dyall-Smith DJ

更新日期：1991-07-01 00:00:00

abstract：:Hodgkin lymphoma (HL) is composed of two distinct pathological entities, nodular lymphocyte predominant HL and classic HL, the latter with four subtypes. In contrast with most other human lymphomas, in which the neoplastic cells are a major population of the tumour constituents, the neoplastic 'Hodgkin (H) and Reed-St...

journal_title：Pathology

authors： Piris MA,Medeiros LJ,Chang KC

更新日期：2020-01-01 00:00:00

abstract：:Malignant pleural mesothelioma (MPM) is often associated with a poor prognosis and options for the treatment of this disease are few. To date, the important role of the immune microenvironment in modifying the disease natural history is well established. The programmed cell death pathway (PD-1/PD-L1) limits the T lymp...

journal_title：Pathology

authors： Rrapaj E,Giacometti L,Spina P,Salvo M,Baselli GA,Veggiani C,Rena O,Trisolini E,Boldorini RL

更新日期：2020-11-30 00:00:00

abstract：:The use of purified intrinsic factor in vitamin B12 radioassays has greatly reduced the misdiagnosis of pernicious anaemia in recent years, but anomalies still occur. Observations made on current vitamin B12 radioassays suggest that many methods fail to convert all serum cobalamins to cyanocobalamin and thus are not t...

journal_title：Pathology

authors： Brown RD,Robin H,Kronenberg H

更新日期：1982-01-01 00:00:00

abstract：:Antibodies that bind phospholipid (anti-phospholipid antibodies [APA]) are a focus of major interest to both clinical and laboratory personnel across a variety of disciplines because of the assortment of disorders with which they are reportedly associated. A solid phase assay using cardiolipin as the test phospholipid...

journal_title：Pathology

authors： Favaloro EJ,Silvestrini R,Mohammed A

更新日期：1999-05-01 00:00:00

abstract：:A 5-year-old Chinese boy had dull pain in his right knee for about one year. An intraosseous osteolytic lesion in the metaphysis of the right lower femur was curetted. The diagnosis of desmoplastic fibroma, possibly the first in a Hong Kong Chinese, was based on the clinical, radiological and histological findings. Ab...

journal_title：Pathology

authors： Chan KW,Pun WK,Choi CH

更新日期：1987-04-01 00:00:00

abstract：:The estrogen receptor (ER) content of breast carcinoma is generally accepted as valuable in predicting clinical outcome and tumour response to hormonal manipulation. We applied a new immunocytochemical assay for estrogen receptors (Abbott ERICA Monoclonal) to 20 breast tumours, and examined the efficacy of 16 fixation...

journal_title：Pathology

authors： Raymond WA,Leong AS

更新日期：1988-10-01 00:00:00

abstract：:Proliferation of isolated hepatocytes in long-term splenic implants was assessed by flash labelling with a 1 pulse of tritiated thymidine (3H TdR). Cell kinetics showed that the basal labelling index was 0.9% which was greater than normal non-regenerating liver. Twenty four hours following partial hepatectomy the labe...

journal_title：Pathology

authors： Gupta S,Johnstone R,Darby H,Selden C,Price Y,Hodgson HJ

更新日期：1987-01-01 00:00:00

abstract：:AxI, Dtk and Mer are recently described receptors that constitute a new receptor tyrosine kinase subfamily. They bind the vitamin K-dependent protein growth-arrest-specific gene 6 (Gas6) that is structurally related to the anticoagulation factor protein S. Studies suggest a role for these receptors in developmental pr...

journal_title：Pathology

authors： Crosier KE,Crosier PS

更新日期：1997-05-01 00:00:00

abstract：:Murine monoclonal antibodies to human myeloid cell surface differentiation antigens were prepared using the myelomonocytic leukemia cell line RC-2A as immunogen. Using a highly sensitive colorimetric assay, antibodies were selected as myeloid-associated based on their binding to RC-2A cells, but not to cells of the au...

journal_title：Pathology

authors： Lyons AB,Cooper SJ,Cole SR,Ashman LK

更新日期：1988-04-01 00:00:00

abstract：:Phospholipid preparations from the nematode Ascaris suum or cysts of Echinococcus granulosus (hydatid cysts) induced an eosinophilia when injected into the peritoneal cavity of rats. Peritoneal eosinophilia persisted throughout 21 days of daily injections of Ascaris lipid and was accompanied by blood eosinophilia, mas...

journal_title：Pathology

authors： Archer GT,Robson JE,Thompson AR

更新日期：1977-04-01 00:00:00

abstract：AIMS:The increasing importance of cardiac disease has generated an interest in improved screening strategies regarding preclinical cardiac abnormalities and employing measurement of circulating biomarkers. This review focuses on the utility of the B-type natriuretic peptides (NP) and the cardiac troponins (cTns) for th...

journal_title：Pathology

authors： Eggers KM,Venge P

更新日期：2012-02-01 00:00:00

abstract：:The alkaline phosphatase from neutrophils of pregnant women and normal males has been extracted, subjected to various inhibitory procedures and to electrophoresis. It is demonstrated that the iso-enzyme obtained from each group is indistinguishable from the skeletal iso-enzyme, in contrast to the serum iso-enzyme of p...

journal_title：Pathology

authors： Findlay AB,Johnston NG

更新日期：1977-01-01 00:00:00

abstract：:Gram negative anaerobic organisms are important pathogens in a range of clinical infections, and susceptibility testing is not commonly performed in the microbiology laboratory. We performed anaerobic susceptibility testing on 70 clinically relevant Gram negative anaerobes isolated from routine cultures in a busy diag...

journal_title：Pathology

authors： Hughes C,Ashhurst-Smith C,Ferguson JK

更新日期：2018-06-01 00:00:00

abstract：:Three cases of nodular lymphomas with cytoplasmic inclusions were studied histologically, histochemically and immunocytochemically, and ultrastructurally. One case had Russell body-like inclusions, another had needle-like inclusions not previously reported, while the last showed cells with cytoplasmic vacuoles. Two of...

journal_title：Pathology

authors： Spagnolo DV,Papadimitriou JM,Matz LR,Walters MN

更新日期：1982-10-01 00:00:00

abstract：:There are few studies addressing survival of diffuse peritoneal mesotheliomas (DPM).In this study, survival data were obtained retrospectively from 73 patients treated with intended cytoreductive surgery for DPM, with a mean follow-up of 42 months. Mesotheliomas were classified as well differentiated papillary (WDPM, ...

journal_title：Pathology

authors： Liu S,Staats P,Lee M,Alexander HR,Burke AP

更新日期：2014-12-01 00:00:00

abstract：:The aim of this study was to establish the diagnostic utility of p53 immunohistochemistry in Barrett's esophagus. Three pathologists reviewed endoscopic biopsy specimens and one surgical specimen derived from 102 subjects in a prospective follow-up series. Dysplasia was graded as negative, indefinite, low grade and hi...

journal_title：Pathology

authors： Khan S,Do KA,Kuhnert P,Pillay SP,Papadimos D,Conrad R,Jass JR

更新日期：1998-05-01 00:00:00

abstract：AIMS:This study was undertaken to investigate the genetic factors underlying the development of multifocality and phenotypic diversity in multifocal papillary thyroid carcinoma (mPTC). METHODS:Loss of heterozygosity (LOH) and BRAF(V600E) mutation status were analysed in a total of 55 individual tumour foci from 18 cas...

journal_title：Pathology

authors： Jovanovic L,Delahunt B,McIver B,Eberhardt NL,Bhattacharya A,Lea R,Grebe SK

更新日期：2010-01-01 00:00:00

abstract：AIMS:Whereas most caspases play roles in apoptosis and/or inflammation, caspase-14 plays a main role in epithelial differentiation. In cancers, expression of caspase-14 is frequently altered and is associated with some clinicopathological characteristics, suggesting caspase-14 might contribute to the pathogenesis of ca...

journal_title：Pathology

authors： Yoo NJ,Soung YH,Lee SH,Jeong EG,Lee SH

更新日期：2007-06-01 00:00:00

abstract：AIMS:There are many variants of papillary carcinoma, and some of these variants have been reported to show biological behaviours differing from that of conventional papillary carcinoma. In this study, we present our experience regarding the prevalence and prognoses of these variants of papillary carcinoma. METHODS:H&E...

journal_title：Pathology

authors： Ito Y,Hirokawa M,Uruno T,Kihara M,Higashiyama T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Miyauchi A

更新日期：2008-10-01 00:00:00

abstract：:An analysis of prognostic factors in 4000 patients with cutaneous malignant melanoma at the Sydney Melanoma Unit and the University of Alabama in Birmingham has demonstrated that the histological features of the primary melanoma become less predictive of survival the more advanced the disease becomes. Thus, whilst 4 f...

journal_title：Pathology

authors： Shaw HM,Balch CM,Soong SJ,Milton GW,McCarthy WH

更新日期：1985-04-01 00:00:00

abstract：:The aims of this study were to investigate the immunohistochemical expression and potential prognostic significance of putative cancer stems cell markers ALDH1, EZH2 and SOX2 in prostate cancer.A total of 142 consecutive radical prostatectomies submitted to one laboratory with a diagnosis of prostatic adenocarcinoma b...

journal_title：Pathology

authors： Matsika A,Srinivasan B,Day C,Mader SA,Kiernan DM,Broomfield A,Fu J,Hooper JD,Kench JG,Samaratunga H

更新日期：2015-12-01 00:00:00

abstract：:Plexiform leiomyomas of the uterus are incidental findings in hysterectomy specimens. Histogenetically, these rare tumors are classified as a variant of epithelioid leiomyomas. Most of the plexiform leiomyomas reported range in size from microscopically small lesions to less than 1 cm in largest diameter, and they mac...

journal_title：Pathology

authors： Nagel H,Brinck U,Lüthje D,Füzesi L

更新日期：1999-08-01 00:00:00

abstract：AIMS:To review the benign bone tumours accessioned by the Bone Tumour Registry (BTR) of Western Australia (WA) during the years 1972-1996 and to determine the incidence of the more common types. METHODS:Information was extracted from the Registry database using 58 selected fields. RESULTS:During the 25 year period, 8...

journal_title：Pathology

authors： Blackwell JB,Curnow MN

更新日期：2007-12-01 00:00:00

abstract：:Multiplex immunofluorescence (mIF) allows simultaneous antibody-based detection and quantification of the expression of up to six markers, plus a nuclear counterstain, on a single tissue section. Recent studies have shown the potential for mIF to advance our understanding of complex disease processes, including cancer...

journal_title：Pathology

authors： Lim JCT,Yeong JPS,Lim CJ,Ong CCH,Wong SC,Chew VSP,Ahmed SS,Tan PH,Iqbal J

更新日期：2018-04-01 00:00:00

abstract：:The early and late effects of wound healing on tumour development at a distant site were evaluated morphologically in an experimental model of colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH). Random bred male Wistar rats were given subcutaneous injections of DMH (20 mg/kg) or saline, once a week, for eight...

journal_title：Pathology

authors： Sequeira JL,Kobayasi SS,Rodrigues MA

更新日期：2000-11-01 00:00:00

abstract：:Since 1967 the Royal College of Pathologists of Australasia has been providing an external quality assurance programme in microbiology. The number of participants has risen from 70 to 222, and the samples distributed for investigation have increased in quantity, now totalling 35-40 per annum, and in variety, so that m...

journal_title：Pathology

authors： Ackerman VP,Pritchard RC

更新日期：1984-07-01 00:00:00

abstract：:The case is reported of a woman aged 60 yrs who presented with systemic symptoms and who was found to have proteinuria of 3.5 g per day. A renal biopsy revealed numerous neoplastic cells filling many of the glomerular capillary lumina. Immunoperoxidase stains revealed that the phenotype of the malignant cells was LCA+...

journal_title：Pathology

authors： Axelsen RA,Laird PP,Horn M

更新日期：1991-07-01 00:00:00

abstract：:Exfoliative, abrasive and aspiration cytology were increasingly relied upon for tissue diagnosis of tumours. The established histological stains for the differentiation of mucin and non-mucin-secreting tumours are not ideal for alcohol-fixed cytology smears and a more reliable cytological technique for the preservatio...

journal_title：Pathology

authors： Nathan NA,van Deth AG

更新日期：1983-07-01 00:00:00

abstract：:The concentration of lactoferrin, a non-heme iron binding glycoprotein, was determined in more than 1500 EDTA plasma samples by a 2-site solid phase immunoradiometric assay to assess the significance of lactoferrin in plasma and to investigate applications for this assay. The use of commercially available antibody and...

journal_title：Pathology

authors： Brown RD,Rickard KA,Kronenberg H

更新日期：1983-01-01 00:00:00