Intracellular acidic mucins and their identification in diagnostic cytology.

abstract：:Lysosome-associated membrane protein-1 (LAMP1) has been suggested to play complicated roles in cancer development and metastasis. The aim of this study was to explore the expression of LAMP1 in laryngeal squamous cell carcinoma (LSCC) and investigate the relationship between LAMP1 expression and clinicopathological ch...

journal_title：Pathology

authors： Lu M,Zhu H,Wang X,Zhang D,Xiong L,Zhu J,Mao Y,Qiang J

更新日期：2016-12-01 00:00:00

abstract：:As autopsy rates in general hospitals decline, interest in the perinatal autopsy continues to rise, reflecting the emergence of a vigorous specialty growing in parallel with fetal medicine, prenatal diagnosis and clinical genetics. Perinatal autopsies are best carried out in tertiary centres which provide these servic...

journal_title：Pathology

authors： Chambers HM

更新日期：1992-04-01 00:00:00

abstract：:We counted apoptotic thymic cortical lymphocytes in semi-thin plastic sections of 266 human autopsy thymuses. The decreased patients included in the study were all aged less than 40 yrs and all died within 72 hrs of the onset of symptoms. Based on published data on animal and human material it was anticipated that ind...

journal_title：Pathology

authors： Middleton G,Reid LE,Harmon BV

更新日期：1994-04-01 00:00:00

abstract：:Biochemical confirmation of the identity of Burkholderia pseudomallei in Singapore previously relied on the API 20NE panel of tests. After introducing an alternative proprietary biochemical panel, the Microbact 24E (MedVet, Adelaide, Australia), we noted that the API panel identified some presumptive B. pseudomallei i...

journal_title：Pathology

authors： Inglis TJ,Chiang D,Lee GS,Chor-Kiang L

更新日期：1998-02-01 00:00:00

abstract：:A strain of Serratia marcescens, isolated from the blood cultures of a patient receiving antibiotics, exhibited 3 unstable properties. These properties were resistance to aminoglycosides, colony size and pigment production. While resistance to aminoglycosides was linked to colony size, pigment production appeared inde...

journal_title：Pathology

authors： Ruhen RW,Wetherall FM

更新日期：1983-01-01 00:00:00

abstract：:Trichostrongylus infection, an uncommonly reported zoonosis in Australia, is common in parts of the world where there is close human contact with herbivorous animals. We report 5 cases diagnosed in our laboratory since 1992. Over this period the laboratory has conducted over 46,000 parasitological examinations on fece...

journal_title：Pathology

authors： Boreham RE,McCowan MJ,Ryan AE,Allworth AM,Robson JM

更新日期：1995-04-01 00:00:00

abstract：:The present conventional methods for determination of Hemoglobin (Hb) concentration in whole blood depend on the direct colorimetric measurement of chemically modified Hb following its release from red cells by lysis. This paper examines an alternative, indirect method which does not require initial red cell lysis, co...

journal_title：Pathology

authors： Kalache GR,Sartor MM,Hughes WG

更新日期：1991-04-01 00:00:00

abstract：:A 40 year old Chinese woman presented with anasarca and later developed features of POEMS syndrome. These are peripheral neuropathy (P), organomegaly (O), endocrine dysfunction (E), monoclonal gammopathy (M), and skin changes (S) which are usually associated with plasma cell dyscrasia. In our patient, monoclonal gammo...

journal_title：Pathology

authors： Leung NW,Lam CW,Pang JC

更新日期：1991-04-01 00:00:00

abstract：:Understanding human genetic variation and how it impacts on gene function is a major focus in genomic-based research. Translation of this knowledge into clinical care is exemplified by pharmacogenetics/pharmacogenomics. The identification of particular gene variants that might influence drug uptake, metabolism, distri...

journal_title：Pathology

authors： Trent RJ,Cheong PL,Chua EW,Kennedy MA

更新日期：2013-06-01 00:00:00

abstract：AIMS:To correlate the immunostaining for INI1 protein and mutations in INI1 gene in possible rhabdoid tumours (RT) and atypical teratoid/rhabdoid tumours (AT/RT) seen at the Royal Children's Hospital in the last 10 years, and to study the clinicopathological features of those patients with negative nuclear staining. M...

journal_title：Pathology

authors： Wu X,Dagar V,Algar E,Muscat A,Bandopadhayay P,Ashley D,Wo Chow C

更新日期：2008-12-01 00:00:00

abstract：:Eccrine syringofibroadenoma is a rare benign tumor of the skin arising from the acrosyringeal portion of the eccrine duct. The tumor was first described by Mascaro in 1963, and since then only 8 case reports in 6 publications have been documented. This lesion is likely to be misdiagnosed both clinically and histologic...

journal_title：Pathology

authors： Billson VR,Dyall-Smith DJ

更新日期：1991-07-01 00:00:00

abstract：:The terminal complement complex has been implicated in the development of glomerular injury in both experimental and, indirectly, in human glomerulonephritis. Recent data suggests that the terminal complement complex in human glomerulonephritis may be in the cytolytically inactive SC5b-9 form which also contains S-pro...

journal_title：Pathology

authors： Murphy BF,Davies DJ,Morrow W,d'Apice AJ

更新日期：1989-10-01 00:00:00

abstract：:Four hundred and ten thyroid nodules, 127 breast lumps and 43 lymph nodes were sampled and analyzed to compare the classical aspiration (ASP) technique with the non aspiration needle jab (NASP) technique. The adequacy of cellularity, significant blood staining and the discomfort felt by the patient were assessed and s...

journal_title：Pathology

authors： Kumarasinghe MP,Sheriffdeen AH

更新日期：1995-10-01 00:00:00

abstract：:Three cases of nodular lymphomas with cytoplasmic inclusions were studied histologically, histochemically and immunocytochemically, and ultrastructurally. One case had Russell body-like inclusions, another had needle-like inclusions not previously reported, while the last showed cells with cytoplasmic vacuoles. Two of...

journal_title：Pathology

authors： Spagnolo DV,Papadimitriou JM,Matz LR,Walters MN

更新日期：1982-10-01 00:00:00

abstract：:In the 20 years that cardiac troponin testing has been available in clinical laboratories, the biomarker has revolutionised testing of patients with acute coronary syndromes. Cardiac troponin I and T testing has become the cornerstone for diagnosis of myocardial infarction and is useful for risk assessment and managem...

journal_title：Pathology

authors： Christenson RH,Phillips D

更新日期：2011-04-01 00:00:00

abstract：:Histopathologists are encountering intra-lobular epithelial proliferations more frequently in core biopsies taken from lesions identified in mammographic breast screening programmes. In particular, columnar cell lesions are increasingly being seen in core biopsies taken for the histological assessment of mammographica...

journal_title：Pathology

authors： Pinder SE,Provenzano E,Reis-Filho JS

更新日期：2007-04-01 00:00:00

abstract：:An enzyme-immunoassay has been developed for the detection of myoglobin in human serum and urine which is specific, accurate, precise, and has a sensitivity of 3 ng/ml. When compared with radioimmunoassay, the enzyme-immunoassay gives markedly similar results. Sera from normal adults had a myoglobin concentration in t...

journal_title：Pathology

authors： Cloonan MJ,Bishop GA,Wilton-Smith PD,Carter IW,Allan RM,Wilcken DE

更新日期：1979-10-01 00:00:00

abstract：:Cryostat sections of livers from rats treated with carbon tetrachloride (CCl4) for 12 weeks were examined by indirect immunofluorescence for reactivity with human serum containing smooth muscle antibody (SMA). Increased binding of SMA serum to hepatocytes was observed as early as the first week of CCl4 treatment and r...

journal_title：Pathology

authors： Toh BH,Cauchi MN,Muller HK

更新日期：1977-07-01 00:00:00

abstract：:The frequency of simultaneous infection with Neisseria gonorrhoeae and Chlamydia trachomatis in men and women in Eastern Sydney was examined prospectively over a 21 month period in patients from whom appropriate specimens were obtained. In men gonococcal disease (113 cases) and chlamydial infections (124 cases) occurr...

journal_title：Pathology

authors： Tapsall JW,Kinchington M

更新日期：1996-01-01 00:00:00

abstract：:A retrospective study of gallbladders submitted as surgical specimens over a period of fifteen years (1972-1986) was performed in the Department of Pathology, Queen Mary Hospital, Hong Kong. Seven thousand nine hundred and ten gallbladders were examined. A total of 253 more unusual and significant pathological lesions...

journal_title：Pathology

authors： Chan KW

更新日期：1988-01-01 00:00:00

abstract：:We aimed to evaluate the diagnostic utility of the novel immunohistochemical marker TROP-2 on thyroid specimens (226 tumours and 207 controls). Whole slide immunohistochemistry was performed and scored by automated digital image analysis. Non-neoplastic thyroid, follicular adenomas, follicular carcinomas, and medullar...

journal_title：Pathology

authors： Bychkov A,Sampatanukul P,Shuangshoti S,Keelawat S

更新日期：2016-08-01 00:00:00

abstract：:A screening method is described for urinary 3-methoxy-4-hydroxy mandelic acid using an initial ion exchange procedure, vanillin formation and extraction into toluene. The technique, is simple, rapid and specific, with a reference value up to 35 mumol (7.0 mg)/day established on 92 normal human subjects. Over 200 patie...

journal_title：Pathology

authors： Rumble BA,Dick M

更新日期：1978-01-01 00:00:00

abstract：:Glomeruli from 48 cases of glomerulonephritis (Gn) were isolated and studied by means of the scanning electron microscope (SEM). Overall glomerular loss due to processing was 2.4%. SEM of these isolated glomeruli showed good preservation of glomerular structure. Changes of the podocyte cell body and its foot processes...

journal_title：Pathology

authors： Ng WL,Chan KW,Ma L

更新日期：1983-04-01 00:00:00

abstract：:The Hippo pathway is a tumour-suppressive pathway and its inactivation is known to be associated with progression and metastasis of various cancers. LATS1/2 (large tumour suppressor homolog 1 and 2), YAP1 (Yes-associated protein 1), and TEAD4 (TEA domain-containing sequence-specific transcription factors 4) are core c...

journal_title：Pathology

authors： Kim E,Ahn B,Oh H,Lee YJ,Lee JH,Lee Y,Kim CH,Chae YS,Kim JY

更新日期：2019-04-01 00:00:00

abstract：AIMS:We have identified in malignant melanoma an angio-tumoural complex in which tumour cells occupy a pericytic location along the endothelium of microvessels without evidence of intravasation. This pericytic angiotropism of melanoma cells, without any sign of intravasation, suggests that melanoma cells may migrate al...

journal_title：Pathology

authors： Barnhill RL,Lugassy C

更新日期：2004-10-01 00:00:00

abstract：:One thousand sera shown to be reactive by one of two commercial enzyme linked immunosorbent assays (ELISA) for antibodies to the AIDS virus were referred to the NSW State Reference Laboratory for confirmatory assays. Each serum was retested by two commercial ELISA systems (Abbott and ENI), the ENI exclusionary H9 ELIS...

journal_title：Pathology

authors： Imrie AA,Kehrer S,Smith GW,Penny R,Cooper DA

更新日期：1986-10-01 00:00:00

abstract：AIMS:This study was undertaken to investigate the genetic factors underlying the development of multifocality and phenotypic diversity in multifocal papillary thyroid carcinoma (mPTC). METHODS:Loss of heterozygosity (LOH) and BRAF(V600E) mutation status were analysed in a total of 55 individual tumour foci from 18 cas...

journal_title：Pathology

authors： Jovanovic L,Delahunt B,McIver B,Eberhardt NL,Bhattacharya A,Lea R,Grebe SK

更新日期：2010-01-01 00:00:00

abstract：:HLA-B27 is a risk marker for ankylosing spondylitis and other associated seronegative spondyloarthropathies. We compared three methods of HLA-B*27 typing in a New South Wales (NSW) population: flow cytometry, rs4349859 single nucleotide polymorphism (SNP) detection assay, and allele-specific real-time polymerase chain...

journal_title：Pathology

authors： Jang HS,Proos A,Koe L,Anderson J,Fulton R,Fernando SL

更新日期：2020-02-01 00:00:00

abstract：:A clinicopathological analysis was made of data from 250 cases of nodular fasciitis. These benign nodules usually occurred in young and middle-aged adults in the 4th and 5th decades, most often in the forearm (27%) followed by the thigh (17%) and the upper arm (12%), and grew rather rapidly to reach a mean diameter of...

journal_title：Pathology

authors： Shimizu S,Hashimoto H,Enjoji M

更新日期：1984-04-01 00:00:00

abstract：:Statistical methods have been used to determine an optimal approach to the definition of the reference range for CD4 ("helper") and CD8 ("suppressor/cytotoxic") T cell numbers and the CD4/CD8 ratio in the peripheral blood. A graphical presentation of the absolute values for CD4 and CD8 for 85 healthy blood donors show...

journal_title：Pathology

authors： Zachar V,Mikulecky M,Mayer V,Mackay I,Frazer I

更新日期：1988-10-01 00:00:00