An improved screening method for 3-methoxy-4-hydroxy mandelic acid excretion in urine.

Abstract:

:A screening method is described for urinary 3-methoxy-4-hydroxy mandelic acid using an initial ion exchange procedure, vanillin formation and extraction into toluene. The technique, is simple, rapid and specific, with a reference value up to 35 mumol (7.0 mg)/day established on 92 normal human subjects. Over 200 patients' urines were analysed by the method of which 18 gave values above the reference range. The majority of these increased excretions are attributed to the metabolic effects of drugs, one patient suffered from phaeochromocytoma and only 2 results remaining unexplained.

journal_name

Pathology

journal_title

Pathology

authors

Rumble BA,Dick M

doi

10.3109/00313027809063479

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

53-7

issue

1

eissn

0031-3025

issn

1465-3931

journal_volume

10

pub_type

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