Abstract:
:A 40 year old Chinese woman presented with anasarca and later developed features of POEMS syndrome. These are peripheral neuropathy (P), organomegaly (O), endocrine dysfunction (E), monoclonal gammopathy (M), and skin changes (S) which are usually associated with plasma cell dyscrasia. In our patient, monoclonal gammopathy was not detected on immunofixation electrophoresis and was revealed only after analysis of kappa/lambda light chain ratio of the raised serum IgA immunoglobulin. Needle liver biopsy of her grossly enlarged liver showed marked accumulation of glycogen and presence of giant mitochondria in the hepatocytes, a feature not previously reported.
journal_name
Pathologyjournal_title
Pathologyauthors
Leung NW,Lam CW,Pang JCdoi
10.3109/00313029109060819subject
Has Abstractpub_date
1991-04-01 00:00:00pages
167-71issue
2eissn
0031-3025issn
1465-3931journal_volume
23pub_type
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