Poems syndrome.

Abstract:

:A 40 year old Chinese woman presented with anasarca and later developed features of POEMS syndrome. These are peripheral neuropathy (P), organomegaly (O), endocrine dysfunction (E), monoclonal gammopathy (M), and skin changes (S) which are usually associated with plasma cell dyscrasia. In our patient, monoclonal gammopathy was not detected on immunofixation electrophoresis and was revealed only after analysis of kappa/lambda light chain ratio of the raised serum IgA immunoglobulin. Needle liver biopsy of her grossly enlarged liver showed marked accumulation of glycogen and presence of giant mitochondria in the hepatocytes, a feature not previously reported.

journal_name

Pathology

journal_title

Pathology

authors

Leung NW,Lam CW,Pang JC

doi

10.3109/00313029109060819

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

167-71

issue

2

eissn

0031-3025

issn

1465-3931

journal_volume

23

pub_type

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