Analysis of cerbB2 expression using a panel of 6 commercially available antibodies.

abstract：:Colonic mucosal biopsies from patients with melanosis coli were examined by electron microscopy. They showed apoptosis of colonic surface epithelial cells and phagocytosis of resulting apoptotic bodies by intraepithelial macrophages. The latter migrated to the lamina propria where intracellular degradation of the apop...

journal_title：Pathology

authors： Walker NI,Smith MM,Smithers BM

更新日期：1993-04-01 00:00:00

abstract：:Antibodies that bind phospholipid (anti-phospholipid antibodies [APA]) are a focus of major interest to both clinical and laboratory personnel across a variety of disciplines because of the assortment of disorders with which they are reportedly associated. A solid phase assay using cardiolipin as the test phospholipid...

journal_title：Pathology

authors： Favaloro EJ,Silvestrini R,Mohammed A

更新日期：1999-05-01 00:00:00

abstract：:A 5-year-old Chinese boy had dull pain in his right knee for about one year. An intraosseous osteolytic lesion in the metaphysis of the right lower femur was curetted. The diagnosis of desmoplastic fibroma, possibly the first in a Hong Kong Chinese, was based on the clinical, radiological and histological findings. Ab...

journal_title：Pathology

authors： Chan KW,Pun WK,Choi CH

更新日期：1987-04-01 00:00:00

abstract：:While localised prostate cancer can be cured by local treatment, 'high-risk' prostate cancer often progresses to castration resistant disease and remains incurable with a dismal prognosis. In recent years, technical advances and development of novel methodologies have largely contributed to a better understanding of u...

journal_title：Pathology

authors： Vlajnic T,Bubendorf L

更新日期：2021-01-01 00:00:00

abstract：AIMS:Whereas most caspases play roles in apoptosis and/or inflammation, caspase-14 plays a main role in epithelial differentiation. In cancers, expression of caspase-14 is frequently altered and is associated with some clinicopathological characteristics, suggesting caspase-14 might contribute to the pathogenesis of ca...

journal_title：Pathology

authors： Yoo NJ,Soung YH,Lee SH,Jeong EG,Lee SH

更新日期：2007-06-01 00:00:00

abstract：AIMS:Matrix metalloproteinases (MMPs) have various functions that play roles in carcinoma development. In this study, we investigated the expression of two representative MMPs, MMP-7 and MMP-11, in papillary thyroid carcinomas. METHODS:We immunohistochemically investigated the expression of these MMPs in 196 cases of ...

journal_title：Pathology

authors： Ito Y,Yoshida H,Kakudo K,Nakamura Y,Kuma K,Miyauchi A

更新日期：2006-10-01 00:00:00

abstract：AIMS:It is currently accepted that primary ovarian tumours rarely, if ever, give rise to mucinous ascites/pseudomyxoma peritonei (PMP) which most commonly results from the intra-abdominal spread of an appendiceal mucinous neoplasm. However, primary ovarian mucinous tumours of appendiceal type arising within mature cyst...

journal_title：Pathology

authors： Stewart CJ,Tsukamoto T,Cooke B,Leung YC,Hammond IG

更新日期：2006-12-01 00:00:00

abstract：:Understanding human genetic variation and how it impacts on gene function is a major focus in genomic-based research. Translation of this knowledge into clinical care is exemplified by pharmacogenetics/pharmacogenomics. The identification of particular gene variants that might influence drug uptake, metabolism, distri...

journal_title：Pathology

authors： Trent RJ,Cheong PL,Chua EW,Kennedy MA

更新日期：2013-06-01 00:00:00

abstract：:An indirect haemaglutination method was developed for the immunochemical detection of myoglobin in human urine. Myoglobin was found in the urine of 84% of 44 patients with acute myocardial infarction. In contrast, it was detected in the urine of 2.7% of 147 control subjects and in none of a control group of 15 patient...

journal_title：Pathology

authors： Cloonan JM,Donald TG,Neale C,Wilcken DE

更新日期：1976-10-01 00:00:00

abstract：:A fatal case of multiple sulfatase deficiency in a 10-year-old girl is reported. In this rare disease, which is inherited as an autosomal recessive, features of metachromatic leukodystrophy and of mucopolysaccharidoses occur together. The white matter suffers progressive destruction with sulfatides accumulating in mac...

journal_title：Pathology

authors： Kepes JJ,Berry A 3rd,Zacharias DL

更新日期：1988-07-01 00:00:00

abstract：AIMS AND METHODS:During colorectal carcinogenesis, transforming growth factor beta 1 (TGF-beta1) undergoes a functional change from suppression of cancer cell proliferation to inhibition of T cell mediated anti-cancer immunity. We aimed to evaluate relations among TGF-beta1 and cancer cell survival factors hypoxia indu...

journal_title：Pathology

authors： Sulkowska M,Wincewicz A,Sulkowski S,Koda M,Kanczuga-Koda L

更新日期：2009-01-01 00:00:00

abstract：:Gene targeting ('knock-out') technology is now widely used in the basic science of all disciplines of pathology and particularly auto-immune and inflammatory disease. Gene targeting is the wilful introduction of precise mutations into the genome of an animal, usually a mouse, affecting the function of a single gene or...

journal_title：Pathology

authors： Riminton DS

更新日期：2002-04-01 00:00:00

abstract：:An unusual case of gliomatosis cerebri in a 37 yr-old man is reported. He presented with a variable clinical picture. Mental changes, brain stem signs, cerebellar signs and rise in intracranial pressure were the constant findings. The postmortem findings are described and the available literature is reviewed. ...

journal_title：Pathology

authors： Balakrishnan V,Hornabrook RW,Alexander WS

更新日期：1985-01-01 00:00:00

abstract：:Recent controversies both in Australia and overseas have focused public attention on autopsy practice. It has become apparent that there is an increasing expectation amongst the public for more detailed information concerning autopsy procedures and, in particular, tissue retention. This article attempts to review the ...

journal_title：Pathology

authors： Lynch MJ

更新日期：2002-02-01 00:00:00

abstract：AIM:Both hypoxia inducible factor 1 (HIF-1) and basic fibroblast growth factor (bFGF) play important roles in tumour angiogenesis. This study was designed to clarify the cooperative effect of these two mediators in induction of vascular endothelial cell growth factor (VEGF) release from breast cancer and probe possible...

journal_title：Pathology

authors： Shi YH,Bingle L,Gong LH,Wang YX,Corke KP,Fang WG

更新日期：2007-08-01 00:00:00

abstract：:Examination of routinely stained haematoxylin and eosin sections may sometimes prove inadequate in differentiating partial hydatidiform moles (PHM) from complete hydatidiform moles (CHM). While cytogenetic analysis can aid in the distinction, such facilities are not always available. The possibility of using immunohis...

journal_title：Pathology

authors： Cheah PL,Looi LM

更新日期：1994-04-01 00:00:00

abstract：:The causes and pathogenesis of severe childhood pneumonia in a developing country were studied in lungs removed at autopsy from 119 Bangladeshi children who presented with pneumonia and/or diarrhea. Pneumonia was observed in 93 patients. Morphologic features included acute alveolar exudate in 51% (of the 93 patients),...

journal_title：Pathology

authors： Tomashefski JF Jr,Butler T,Islam M

更新日期：1989-04-01 00:00:00

abstract：AIMS:BRAF mutation has been shown in a large meta-analysis to be an independent prognostic marker for papillary thyroid carcinoma (PTC) with poorer survival and higher recurrence rates. METHODS:We studied prevalence of BRAF mutation in 77 patients with PTC from an Australian cohort using competitive polymerase chain r...

journal_title：Pathology

authors： McKelvie PA,Chan F,Yu Y,Waring P,Gresshoff I,Farrell S,Williams RA

更新日期：2013-12-01 00:00:00

abstract：:The aim of the present study is to describe the histological and mutational characteristics of a series of both large and small bowel adenocarcinomas in patients with Crohn's disease from a tertiary referral centre of inflammatory bowel disease. Bowel adenocarcinoma was diagnosed in 11 (1.7%) of 660 consecutive patien...

journal_title：Pathology

authors： Malvi D,Vasuri F,Mattioli B,Gruppioni E,Fiorentino M,Gionchetti P,Grigioni WF,Poggioli G,D'Errico-Grigioni A

更新日期：2014-08-01 00:00:00

abstract：:Deregulation of the receptors of TNF-related apoptosis inducing ligand (TRAIL) has been reported in various cancers. In an effort to define the role of these receptors we profiled their expression in gallbladder cancer (GBC) and explored their clinical significance. Expression of TRAIL receptors' mRNA in GBC was analy...

journal_title：Pathology

authors： Singh D,Prasad CB,Biswas D,Tewari M,Kar AG,Ansari MA,Singh S,Narayan G

更新日期：2020-04-01 00:00:00

abstract：:Oral cancer is a serious public health problem, with over 200,000 new cases reported annually worldwide, two-thirds of which occur in developing countries. The overall mortality rate for intra-oral cancer remains high at approximately 50%, even with modern medical services, probably due to the advanced stage of the di...

journal_title：Pathology

authors： Walker DM,Boey G,McDonald LA

更新日期：2003-10-01 00:00:00

abstract：:We present the clinical and postmortem findings in seven adults (four females and three males), who died with dissection of the coronary arteries. The median age was 56 years. Five of the coronary artery dissections (CADs) were spontaneous and two followed trauma: one a motor vehicle accident, the other occurred durin...

journal_title：Pathology

authors： Mulvany NJ,Ranson DL,Pilbeam MC

更新日期：2001-08-01 00:00:00

abstract：:We report a patient with unusual venous and arterial thromboses in association with the common thermolabile methyltetrahydrofolate (MTHFR) variant. The patient responded directly to folate supplementation. To our knowledge, this is the first report describing hyperhomocysteinemia in association with this type of throm...

journal_title：Pathology

authors： Hall TN,Ramakrishnan LL,Leahy MF

更新日期：1999-02-01 00:00:00

abstract：:The in vitro activity of azthreonam, a novel monocyclic beta-lactam antibiotic, was investigated for Gram negative urinary pathogens by determining the susceptibilities of 105 consecutive isolates from specimens submitted to the Auckland Hospital microbiology laboratory. All were sensitive or of intermediate sensitivi...

journal_title：Pathology

authors： Lang SD,McKenzie D

更新日期：1983-04-01 00:00:00

abstract：:A strain of Serratia marcescens, isolated from the blood cultures of a patient receiving antibiotics, exhibited 3 unstable properties. These properties were resistance to aminoglycosides, colony size and pigment production. While resistance to aminoglycosides was linked to colony size, pigment production appeared inde...

journal_title：Pathology

authors： Ruhen RW,Wetherall FM

更新日期：1983-01-01 00:00:00

abstract：:The application of glucose point of care testing (PoCT) in hospitals has been a contentious subject for many years. No information is available regarding the extent to which glucose PoCT is used within the Australian hospital system and whether such testing is fit for its intended purpose. The aim of this study was to...

journal_title：Pathology

authors： Sharp L,Farrance I,Greaves RF

更新日期：2016-01-01 00:00:00

abstract：AIM:1) To determine the prevalence of hepatitis B in Sydney autopsies and 2) to determine the relationship between seroprevalence, hepatitis B risk factors and histological changes in the liver. METHODS:One hundred autopsy subjects were studied for evidence of past or present hepatitis B infection, using RIA to detect...

journal_title：Pathology

authors： Ashwell MJ,Cossart YE

更新日期：1995-01-01 00:00:00

abstract：:Patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) often exhibit clonal chromosomal abnormalities. Using a probe for the centromeric region of chromosome 8, fluorescence in situ hybridization (FISH) on interphase cells was used to detect trisomy 8 in an AML patient whose leukemia was characte...

journal_title：Pathology

authors： White DL,Hutchins CJ,Turczynowicz S,Suttle J,Haylock DN,Hughes TP,Juttner CA,To LB

更新日期：1997-08-01 00:00:00

abstract：:Serial bone marrow aspirates were obtained from 16 adults with acute myeloid leukaemia (AML) before and after a single infusion of cytarabine (5.0 mg/kg i.v. over 30 min). Changes in the proliferative activity of the leukaemic myeloblasts were monitored by determination of the labelling index (LI) and the mitotic inde...

journal_title：Pathology

authors： Buchanan JG,Matthews JR,Postlewaight BF,Upsdell M

更新日期：1979-07-01 00:00:00

abstract：:The aims of this study were to assess the value of specimen radiographs of stereotactic core biopsy, the usefulness of measuring size of calcifications on tissue sections, whether demonstration of calcifications in tissue sections alters the pathological diagnosis when specimen radiograph demonstrates calcifications, ...

journal_title：Pathology

authors： Dahlstrom JE,Jain S

更新日期：2001-11-01 00:00:00