Inverse relationships between the expression of MMP-7 and MMP-11 and predictors of poor prognosis of papillary thyroid carcinoma.

abstract：:IgG4 related disease (IgG4RD) is a recently recognised condition characterised by mass forming lesions associated with storiform fibrosis, obliterative phlebitis, lymphoplasmacytic infiltrate rich in IgG4 positive plasma cells and elevated serum IgG4 levels. Although rare, mammary involvement has been reported as IgG4...

journal_title：Pathology

authors： Chougule A,Bal A,Das A,Singh G

更新日期：2015-01-01 00:00:00

abstract：:Isolation of the new pandemic virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for diagnostic and research purposes including assessment of novel therapeutics. Several primary and continuous cell lines are currently used, and new organoid and engineered cell lines are being developed for...

journal_title：Pathology

authors： Stelzer-Braid S,Walker GJ,Aggarwal A,Isaacs SR,Yeang M,Naing Z,Ospina Stella A,Turville SG,Rawlinson WD

更新日期：2020-12-01 00:00:00

abstract：AIMS:CD146 is a potentially metastasis promoting cell adhesion molecule and its expression has been described in various solid tumours. We aimed to evaluate the expression of CD146 in prostate cancer by immunohistochemistry in a clinically characterised study cohort to evaluate its prognostic properties. METHODS:We ev...

journal_title：Pathology

authors： Fritzsche FR,Wassermann K,Rabien A,Schicktanz H,Dankof A,Loening SA,Dietel M,Jung K,Kristiansen G

更新日期：2008-08-01 00:00:00

abstract：AIMS:In our previous studies, comparative proteomics demonstrated that lactate dehydrogenase B subunit (LDH-B) is down-regulated in high grade compared to non-high grade urinary bladder urothelial carcinoma (UBUC). However, this finding has not been validated by clinical cohort investigation. Therefore, in the present ...

journal_title：Pathology

authors： Liao AC,Li CF,Shen KH,Chien LH,Huang HY,Wu TF

更新日期：2011-12-01 00:00:00

abstract：AIM:Considering the fact that histology and its grading systems are accepted gold standards in diagnosis of diverse clinical disorders, assessing the accuracy and reliability of this method of diagnosis is of utmost importance. Thus, this study was performed to measure the agreement values between four independent hist...

journal_title：Pathology

authors： Talebkhan Y,Mohammadi M,Rakhshani N,Abdirad A,Fayaz Moughadam K,Fereidooni F

更新日期：2009-01-01 00:00:00

abstract：:A strain of Serratia marcescens, isolated from the blood cultures of a patient receiving antibiotics, exhibited 3 unstable properties. These properties were resistance to aminoglycosides, colony size and pigment production. While resistance to aminoglycosides was linked to colony size, pigment production appeared inde...

journal_title：Pathology

authors： Ruhen RW,Wetherall FM

更新日期：1983-01-01 00:00:00

abstract：:In order to determine whether routine culturing for Clostridium difficile was warranted or whether culturing a selected group of patients was adequate, we conducted a prospective trial of culturing all stool specimens for C. difficile. A total of 408 specimens from 297 patients was studied. Two hundred and eighteen st...

journal_title：Pathology

authors： Bowman RA,Riley TV

更新日期：1984-07-01 00:00:00

abstract：:Tumor cell-platelet interactions have been shown to be involved in the process of metastasis. This study characterizes the aggregation of washed platelets induced by the human uterine carcinosarcoma Colo 526. Ultrastructural studies revealed a two-stage process in which the earliest events were the adhesion and degran...

journal_title：Pathology

authors： Bradley CJ,Dauer RJ,Thurlow PJ,Connellan JM

更新日期：1997-05-01 00:00:00

abstract：:A clinicopathological analysis was made of data from 250 cases of nodular fasciitis. These benign nodules usually occurred in young and middle-aged adults in the 4th and 5th decades, most often in the forearm (27%) followed by the thigh (17%) and the upper arm (12%), and grew rather rapidly to reach a mean diameter of...

journal_title：Pathology

authors： Shimizu S,Hashimoto H,Enjoji M

更新日期：1984-04-01 00:00:00

abstract：:The clinical and autopsy findings in a premature baby who died of acute renal failure after therapy with gentamicin (5 mg/kg/day) and penicillin are presented. The serum gentamicin concentration had reached toxic levels when anuria developed. Numerous periodic acid Schiff (PAS) positive, diastase resistant cytoplasmic...

journal_title：Pathology

authors： Chan KW,Ng WL

更新日期：1985-07-01 00:00:00

abstract：AIMS:Mounting evidence indicates that deregulation of apoptosis is involved in the mechanisms of cancer development. Bax-interacting factor-1 (Bif-1) interacts with both Bax and Bak that are crucial for the intrinsic apoptosis signalling. Functionally, loss of Bif-1 expression has been proven to enhance tumorigenesis. ...

journal_title：Pathology

authors： Kim SY,Oh YL,Kim KM,Jeong EG,Kim MS,Yoo NJ,Lee SH

更新日期：2008-10-01 00:00:00

abstract：AIMS:INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ). METHODS:INI1 was determined by immunohistochemistry and MGMT by methylation-specific PCR. RESULTS...

journal_title：Pathology

authors： Zunarelli E,Bigiani N,Sartori G,Migaldi M,Sgambato A,Maiorana A

更新日期：2011-01-01 00:00:00

abstract：:Apoptosis in the myocardium is complex and often difficult to recognise. Myocyte apoptosis is scattered across the myocardial wall and is restricted to individual cells. In the present study, we describe the amount of apoptosis in 50 endomyocardial biopsies taken from 50 patients with dilated cardiomyopathy, in 14 hea...

journal_title：Pathology

authors： Kavantzas NG,Lazaris AC,Agapitos EV,Nanas J,Davaris PS

更新日期：2000-08-01 00:00:00

abstract：:E-cadherin mediated intercellular adhesion is regulated by a family of cytoplasmic proteins that include alpha-, beta- and gamma-catenin and p120cas. Changes in expression of E-cadherin are believed to be an early event in melanoma development. Recent studies have also drawn attention to the over-expression of beta-ca...

journal_title：Pathology

authors： Zhang XD,Hersey P

更新日期：1999-08-01 00:00:00

abstract：:Soft tissue tumours represent a heterogeneous group of mesenchymal lesions and their classification continues to evolve as a result of incorporating advances in cytogenetic and molecular techniques. In the last decade, traditional diagnostic approaches were supplemented with a significant number of reliable molecular ...

journal_title：Pathology

authors： Antonescu CR,Dal Cin P

更新日期：2014-02-01 00:00:00

abstract：:While localised prostate cancer can be cured by local treatment, 'high-risk' prostate cancer often progresses to castration resistant disease and remains incurable with a dismal prognosis. In recent years, technical advances and development of novel methodologies have largely contributed to a better understanding of u...

journal_title：Pathology

authors： Vlajnic T,Bubendorf L

更新日期：2021-01-01 00:00:00

abstract：:The failure of N. gonorrhoeae to grow on isolation media was found to be due to inhibitory substances present in commercially available horse sera. Subsequent investigations indicated that the inhibitory action of the horse serum may have been due to antibodies to N. gonorrhoeae, H. influenzae, H. parainfluenzae and b...

journal_title：Pathology

authors： Mugg PA,Hill A

更新日期：1984-07-01 00:00:00

abstract：:A 14 yr old girl presented with a large cystic mass in the transverse mesocolon which was completely excised. Cystic lymphangioma was diagnosed, based on the specific histologic, immunoperoxidase and ultrastructural findings. ...

journal_title：Pathology

authors： Yuen ST,Ng IO,Ho J,Ma L

更新日期：1992-07-01 00:00:00

abstract：:Rare tumours are a heterogeneous group of conditions that encompass benign to malignant lesions both of stromal and epithelial origin. Here some of these tumours are described, in which the authors have most familiarity. An outline of medullary carcinoma is also presented. ...

journal_title：Pathology

authors： Foschini MP,Eusebi V

更新日期：2009-01-01 00:00:00

abstract：:A unique complication of florid xanthogranulomatous cholecystitis with cholecystoduodenal fistula formation is described in a 6 yr old male. The patient, who had a short gut syndrome, had been maintained on lifelong total parenteral nutrition (TPN) following extensive neonatal ischemic bowel necrosis secondary to gast...

journal_title：Pathology

authors： Byard RW,Thorner PS,Cutz E,Filler RM,Durie P

更新日期：1990-10-01 00:00:00

abstract：:Three cases of nodular lymphomas with cytoplasmic inclusions were studied histologically, histochemically and immunocytochemically, and ultrastructurally. One case had Russell body-like inclusions, another had needle-like inclusions not previously reported, while the last showed cells with cytoplasmic vacuoles. Two of...

journal_title：Pathology

authors： Spagnolo DV,Papadimitriou JM,Matz LR,Walters MN

更新日期：1982-10-01 00:00:00

abstract：:The use of purified intrinsic factor in vitamin B12 radioassays has greatly reduced the misdiagnosis of pernicious anaemia in recent years, but anomalies still occur. Observations made on current vitamin B12 radioassays suggest that many methods fail to convert all serum cobalamins to cyanocobalamin and thus are not t...

journal_title：Pathology

authors： Brown RD,Robin H,Kronenberg H

更新日期：1982-01-01 00:00:00

abstract：:Micropapillary carcinoma of the colon and rectum is associated with an adverse prognosis. This tumour type displays reverse polarity of the tumour cells and is stated to be characterised by an inside-out epithelial membrane antigen (EMA)/MUC1 staining. Nine cases of primary colorectal carcinoma and one omental metasta...

journal_title：Pathology

authors： Cserni G

更新日期：2014-10-01 00:00:00

abstract：:In various tumor types dentritic cell, infiltration and the presence of tumor-infiltrating lymphocytes have been associated with an improved clinical outcome. In the uterine cervix these immunocompetent cells have been associated with improved prognosis in high stage disease. The current study examines the significanc...

journal_title：Pathology

authors： Bethwaite PB,Holloway LJ,Thornton A,Delahunt B

更新日期：1996-11-01 00:00:00

abstract：:A male iniencephalic foetus of about 25 weeks gestation is described. The baby was born to a 22-year-old mother, who presented with abdominal pain of 1 day duration. An ultrasound scan at that time showed multiple foetal anomalies and the pregnancy was terminated. A stillborn baby was delivered. At autopsy, characteri...

journal_title：Pathology

authors： Loo CK,Freeman B,Stanford D

更新日期：2001-02-01 00:00:00

abstract：:Assessment of the risk of lymph node invasion and tumour recurrence is critical to determine whether additional surgery is required in patients with endoscopically-removed pT1 colorectal cancer (CRC). A reproducible assessment of this risk of recurrence based on histopathological parameters is crucial for relevant the...

journal_title：Pathology

authors： Barel F,Auffret A,Cariou M,Kermarrec T,Samaison L,Bourhis A,Badic B,Jézéquel J,Cholet F,Bail JP,Marcorelles P,Nousbaum JB,Robaszkiewicz M,Doucet L,Uguen A

更新日期：2019-01-01 00:00:00

abstract：:We report a case of a 25-year-old man who presented with a large rectal bleed and positive Meckel's scan followed by surgical excision of a Meckel's diverticulum. The diverticulum was lined by gastric body type mucosa showing evidence of active chronic gastritis associated with the presence of Helicobacter pylori orga...

journal_title：Pathology

authors： Hill P,Rode J

更新日期：1998-02-01 00:00:00

abstract：:We report a patient with unusual venous and arterial thromboses in association with the common thermolabile methyltetrahydrofolate (MTHFR) variant. The patient responded directly to folate supplementation. To our knowledge, this is the first report describing hyperhomocysteinemia in association with this type of throm...

journal_title：Pathology

authors： Hall TN,Ramakrishnan LL,Leahy MF

更新日期：1999-02-01 00:00:00

abstract：AIM:To compare the relative diagnostic efficacy of several different tests used to establish a diagnosis of phaeochromocytoma, in patients with a proven diagnosis of phaeochromocytoma, and in hospital patients with significant disease of other types. METHODS:We prospectively compared biochemical markers of catecholami...

journal_title：Pathology

authors： Hickman PE,Leong M,Chang J,Wilson SR,McWhinney B

更新日期：2009-02-01 00:00:00

abstract：:We describe a case of ductal carcinoma in situ (DCIS) occurring in a fibroadenoma diagnosed by fine needle aspiration (FNA) cytology. The cytological features comprised a small population of pleomorphic cells admixed with a dominant population of bland epithelial cells showing features consistent with those of a fibro...

journal_title：Pathology

authors： Psarianos T,Kench JG,Ung OA,Bilous AM

更新日期：1998-11-01 00:00:00