Histopathology and etiology of childhood pneumonia: an autopsy study of 93 patients in Bangladesh.


:The causes and pathogenesis of severe childhood pneumonia in a developing country were studied in lungs removed at autopsy from 119 Bangladeshi children who presented with pneumonia and/or diarrhea. Pneumonia was observed in 93 patients. Morphologic features included acute alveolar exudate in 51% (of the 93 patients), necrotizing pneumonia in 31%, interstitial pneumonia in 22%, and caseating granulomas in 4%, while a mixed pattern occurred in 16% of patients. Causes of pneumonia were Gram-negative bacteria in 27%, pneumococcus in 8%, cytomegalovirus (CMV) in 8%, Pneumocystis carinii (PC) in 4%, mycobacteria in 3%, aspergillus in 3%, mixed anaerobes in 3%, viral (not CMV) in 2%, Staphylococcus aureus in 1% and ascaris in 1%. Two causative agents were identified in 7% of patients. In 46% of the cases, no etiologic agent was identified. Our data suggest that most pneumonias had a bacterial etiology; however, viruses, including CMV, and other opportunistic organisms such as PC, were also important pathogens. Gram-negative pneumonia was partially attributed to concomitant intestinal infections. Opportunistic infections resulted from malnutrition and debilitated host defenses during prolonged fatal illnesses.






Tomashefski JF Jr,Butler T,Islam M




Has Abstract


1989-04-01 00:00:00












  • 'Why don't they ever call?' Expectations of clinicians and pathologists regarding the communication of critical diagnoses in dermatopathology.

    abstract::Certain diagnoses in dermatopathology have significant implications for patient management and on occasion appropriate clinical care may be facilitated by a phone call from the reporting dermatopathologist to the referring doctor. Whether this is appropriate depends on a number of factors. The concept of 'critical dia...


    pub_type: 杂志文章


    authors: Korbl JD,Wood BA,Harvey NT

    更新日期:2018-04-01 00:00:00

  • Fibrillin-1, a novel TGF-beta-induced factor, is preferentially expressed in metaplastic carcinoma with spindle sarcomatous metaplasia.

    abstract::TGF-β induces epithelial-mesenchymal transition (EMT), which is involved in tumour progression. This study aims to identify and characterise novel factors potentially related to TGF-β-mediated tumour aggression in breast cancer. We treated the human mammary epithelial cell line MCF10A with TGF-β and observed TGF-β-dep...


    pub_type: 杂志文章


    authors: Lien HC,Lee YH,Juang YL,Lu YT

    更新日期:2019-06-01 00:00:00

  • Comparison of thromboplastins using the ISI and INR system.

    abstract::Twelve thromboplastins were tested against a secondary reference thromboplastin (human brain CRM BCR No. 147) or a tertiary house standard (human brain thromboplastin) with plasmas from normal healthy individuals and patients on oral anticoagulant therapy. The relationship between the prothrombin ratios of the thrombo...


    pub_type: 杂志文章


    authors: Moriarty HT,Lam-Po-Tang PR,Anastas N

    更新日期:1990-04-01 00:00:00

  • The perinatal autopsy: a contemporary approach.

    abstract::As autopsy rates in general hospitals decline, interest in the perinatal autopsy continues to rise, reflecting the emergence of a vigorous specialty growing in parallel with fetal medicine, prenatal diagnosis and clinical genetics. Perinatal autopsies are best carried out in tertiary centres which provide these servic...


    pub_type: 杂志文章,评审


    authors: Chambers HM

    更新日期:1992-04-01 00:00:00

  • Large cell undifferentiated carcinoma of the urinary bladder.

    abstract::We present the clinicopathological features of eight cases of large cell undifferentiated bladder carcinoma not otherwise specified (LCUBC). LCUBC was characterised by sheets of large polygonal or round cells with moderate to abundant cytoplasm and distinct cell borders. The LCUBC component varied from 90 to 100% of t...


    pub_type: 杂志文章


    authors: Lopez-Beltran A,Cheng L,Comperat E,Rouprêt M,Blanca A,Menendez CL,Montironi R

    更新日期:2010-06-01 00:00:00

  • Ovarian sex cord-stromal tumours: an update in recent molecular advances.

    abstract::Sex cord-stromal tumours (SCSTs) consist of a heterogeneous group of neoplasms with diverse clinicopathological features and biological behaviour. They often present as a diagnostic challenge as they have varied and occasionally overlapping histomorphology and some may even mimic non-SCSTs. An accurate diagnosis is im...


    pub_type: 杂志文章,评审


    authors: Lim D,Oliva E

    更新日期:2018-02-01 00:00:00

  • Gene targeting technology and advances in the pathophysiology of inflammation.

    abstract::Gene targeting ('knock-out') technology is now widely used in the basic science of all disciplines of pathology and particularly auto-immune and inflammatory disease. Gene targeting is the wilful introduction of precise mutations into the genome of an animal, usually a mouse, affecting the function of a single gene or...


    pub_type: 杂志文章,评审


    authors: Riminton DS

    更新日期:2002-04-01 00:00:00

  • Transplanted isolated hepatocytes: effect of partial hepatectomy on proliferation of long-term syngeneic implants in rat spleen.

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    pub_type: 杂志文章


    authors: Gupta S,Johnstone R,Darby H,Selden C,Price Y,Hodgson HJ

    更新日期:1987-01-01 00:00:00

  • The pathology of oral cancer.

    abstract::Oral cancer is a serious public health problem, with over 200,000 new cases reported annually worldwide, two-thirds of which occur in developing countries. The overall mortality rate for intra-oral cancer remains high at approximately 50%, even with modern medical services, probably due to the advanced stage of the di...


    pub_type: 杂志文章,评审


    authors: Walker DM,Boey G,McDonald LA

    更新日期:2003-10-01 00:00:00

  • Aeromonas septicemia: relationship of species and clinical features.

    abstract::Thirteen patients with Aeromonas species septicemia were seen at Westmead Hospital between 1983 and 1987. In 10 patients (77%) septicemia was caused by A. sobria, and in 3 (23%) by A. hydrophila, A. caviae was not isolated. Chronic underlying illness was present in 10 patients (77%), hematological malignancy being the...


    pub_type: 杂志文章


    authors: Dryden M,Munro R

    更新日期:1989-04-01 00:00:00

  • Detection of copy number variations in melanocytic lesions utilising array based comparative genomic hybridisation.

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    pub_type: 杂志文章


    authors: Mesbah Ardakani N,Thomas C,Robinson C,Mina K,Harvey NT,Amanuel B,Wood BA

    更新日期:2017-04-01 00:00:00

  • Perhexiline maleate induced cirrhosis.

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    pub_type: 杂志文章


    authors: Pieterse AS,Rowland R,Dunn D

    更新日期:1983-04-01 00:00:00

  • Interobserver variations in histopathological assessment of gastric pathology.

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    pub_type: 杂志文章


    authors: Talebkhan Y,Mohammadi M,Rakhshani N,Abdirad A,Fayaz Moughadam K,Fereidooni F

    更新日期:2009-01-01 00:00:00

  • Application of an immunoradiometric assay for thyrotrophin in evaluation of thyroidal and nonthyroidal disease states.

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    pub_type: 杂志文章


    authors: McLellan GH,Riley WJ,Summers MB,Sudholz P,Hickman PE

    更新日期:1987-07-01 00:00:00

  • Sensitive and high sensitivity next generation cardiac troponin assays: more than just a name.

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    pub_type: 杂志文章,评审


    authors: Christenson RH,Phillips D

    更新日期:2011-04-01 00:00:00

  • New insights into the control of cell growth; the role of the AxI family.

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    pub_type: 杂志文章,评审


    authors: Crosier KE,Crosier PS

    更新日期:1997-05-01 00:00:00

  • Review of 253 cases of significant pathology in 7,910 cholecystectomies in Hong Kong.

    abstract::A retrospective study of gallbladders submitted as surgical specimens over a period of fifteen years (1972-1986) was performed in the Department of Pathology, Queen Mary Hospital, Hong Kong. Seven thousand nine hundred and ten gallbladders were examined. A total of 253 more unusual and significant pathological lesions...


    pub_type: 杂志文章


    authors: Chan KW

    更新日期:1988-01-01 00:00:00

  • Benign melanocytic lesions mimicking melanomas.

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    pub_type: 杂志文章,评审


    authors: Cook MG

    更新日期:2004-10-01 00:00:00

  • Histological assessment of apoptotic cell death in cardiomyopathies.

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    pub_type: 杂志文章


    authors: Kavantzas NG,Lazaris AC,Agapitos EV,Nanas J,Davaris PS

    更新日期:2000-08-01 00:00:00

  • Early and late effects of wound healing on development of colon tumours in a model of colon carcinogenesis by 1,2-dimethylhydrazine in the rat.

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    pub_type: 杂志文章


    authors: Sequeira JL,Kobayasi SS,Rodrigues MA

    更新日期:2000-11-01 00:00:00

  • LAMP1 expression is associated with malignant behaviours and predicts unfavourable prognosis in laryngeal squamous cell carcinoma.

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    pub_type: 杂志文章


    authors: Lu M,Zhu H,Wang X,Zhang D,Xiong L,Zhu J,Mao Y,Qiang J

    更新日期:2016-12-01 00:00:00

  • Diagnostic performance of a commercial immunoblot assay for myositis antibody testing.

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    pub_type: 杂志文章


    authors: Bundell C,Rojana-Udomsart A,Mastaglia F,Hollingsworth P,McLean-Tooke A

    更新日期:2016-06-01 00:00:00

  • Molecular pathology of prostate cancer: a practical approach.

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    pub_type: 杂志文章,评审


    authors: Vlajnic T,Bubendorf L

    更新日期:2021-01-01 00:00:00

  • Aneuploidy in sclerosing adenosis may predict an increased risk of malignancy. A study using the AgNOR silver stain.

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    pub_type: 临床试验,杂志文章


    authors: Mourad WA

    更新日期:1997-08-01 00:00:00

  • High accuracy of HLA-B*27 genotyping by allele-specific real-time polymerase chain reaction in a heterogeneous population compared to flow cytometry and single nucleotide polymorphism detection assays.

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    pub_type: 杂志文章


    authors: Jang HS,Proos A,Koe L,Anderson J,Fulton R,Fernando SL

    更新日期:2020-02-01 00:00:00

  • Prevalence and biological behaviour of variants of papillary thyroid carcinoma: experience at a single institute.

    abstract:AIMS:There are many variants of papillary carcinoma, and some of these variants have been reported to show biological behaviours differing from that of conventional papillary carcinoma. In this study, we present our experience regarding the prevalence and prognoses of these variants of papillary carcinoma. METHODS:H&E...


    pub_type: 杂志文章


    authors: Ito Y,Hirokawa M,Uruno T,Kihara M,Higashiyama T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Miyauchi A

    更新日期:2008-10-01 00:00:00

  • Progressing the utilisation of pharmacogenetics and pharmacogenomics into clinical care.

    abstract::Understanding human genetic variation and how it impacts on gene function is a major focus in genomic-based research. Translation of this knowledge into clinical care is exemplified by pharmacogenetics/pharmacogenomics. The identification of particular gene variants that might influence drug uptake, metabolism, distri...


    pub_type: 杂志文章,评审


    authors: Trent RJ,Cheong PL,Chua EW,Kennedy MA

    更新日期:2013-06-01 00:00:00

  • Cutaneous relapse of nasal T-cell lymphoma clinically mimicking erythema multiforme.

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    pub_type: 杂志文章


    authors: Chan JK,Sin VC,Ng CS,Lau WH

    更新日期:1989-07-01 00:00:00

  • Plexiform leiomyoma of the uterus in a patient with breast carcinoma: case report and review of the literature.

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    pub_type: 杂志文章,评审


    authors: Nagel H,Brinck U,Lüthje D,Füzesi L

    更新日期:1999-08-01 00:00:00

  • Heat shock protein induction in fetal mouse brain as a measure of stress after whole of gestation exposure to mobile telephony radiofrequency fields.

    abstract:AIM:To determine whether whole of gestation exposure of fetal mouse brain to mobile telephone radiofrequency fields produces a stress response detectable by induction of heat shock proteins (HSPs). METHODS:Using a purpose-designed exposure system at 900 MHz, pregnant mice were given a single, far-field, whole body exp...


    pub_type: 杂志文章


    authors: Finnie JW,Chidlow G,Blumbergs PC,Manavis J,Cai Z

    更新日期:2009-01-01 00:00:00