Peripheral nerve and vasculature involvement in myophosphorylase deficiency (McArdle's disease).

abstract：:Prenatal diagnoses of the genetic disorders alpha, beta thalassemia, HbS, Hb Lepore, hemophilia and cystic fibrosis were sought in 88 cases. Six unsuccessful attempts at diagnosis resulted from DNA polymorphisms which were only 50% informative (four cases) and prenatal diagnoses which had been undertaken before it was...

journal_title：Pathology

authors： Trent RJ,Volpato F,Wallace RC,Lindeman R,Yakas J

更新日期：1990-07-01 00:00:00

abstract：:A case of chronic endometritis with unusual histological features due to the presence of abundant foam cells and lipid material is described. The presence of foam cells, abundant intra- and extracellular lipid together with other inflammatory cells in the absence of endometrial hyperplasia or carcinoma warrants the di...

journal_title：Pathology

authors： Barua R,Kirkland JA,Petrucco OM

更新日期：1978-04-01 00:00:00

abstract：:Although most carcinomas of the bladder occur de novo, some vesical lesions progress to malignancy over time. These lesions appear morphologically benign, but often harbour genetic changes that signify their malignant potential. Despite their benign appearance, accurate identification is important given that these pat...

journal_title：Pathology

authors： Samaratunga H,Martignoni G,Egevad L,Delahunt B

更新日期：2013-04-01 00:00:00

abstract：:A 59 yr old male presented with abdominal pain and jaundice. CT scan showed a tumor in the pancreas with secondaries in the liver, peri-pancreatic lymph nodes, vertebral bone marrow and subcutaneous tissue of the neck together with a cervical lymph node. The patient died after 2 wks and autopsy revealed complete repla...

journal_title：Pathology

authors： Chetty R,Clark SP,Pitson GA

更新日期：1993-07-01 00:00:00

abstract：:Solitary fibrous tumour (SFT) is well-described in the urinary tract, but malignant examples are rare. We studied our experience with high grade malignant SFT of the prostate to address the degree of histological and immunophenotypical overlap with sarcomatoid carcinoma and prostatic stromal sarcoma. Four cases were i...

journal_title：Pathology

authors： Bakhshwin A,Berry RS,Cox RM,Li R,Reynolds JP,Rubin BP,McKenney JK

更新日期：2020-10-01 00:00:00

abstract：AIMS:Mounting evidence indicates that deregulation of apoptosis is involved in the mechanisms of cancer development. Bax-interacting factor-1 (Bif-1) interacts with both Bax and Bak that are crucial for the intrinsic apoptosis signalling. Functionally, loss of Bif-1 expression has been proven to enhance tumorigenesis. ...

journal_title：Pathology

authors： Kim SY,Oh YL,Kim KM,Jeong EG,Kim MS,Yoo NJ,Lee SH

更新日期：2008-10-01 00:00:00

abstract：:Soft tissue tumours are relatively rare, but are diagnostically challenging as they comprise a large spectrum of diagnostic entities. Substantial advances have been made in recent years in identifying the underlying recurrent chromosomal and genomic alterations in a significant subset of soft tissue tumours, and this ...

journal_title：Pathology

authors： Schaefer IM,Fletcher CDM

更新日期：2018-01-01 00:00:00

abstract：:Epigenetic regulation is emerging as a critical mechanism for pancreatic ductal adenocarcinoma (PDA) development. Histone methylation is an important regulatory mechanism, altering chromatin structure and promoter accessibility and causing aberrant gene expression. NSD1 and SETD2 genes encoding two histone H3K36 methy...

journal_title：Pathology

authors： Ettel M,Zhao L,Schechter S,Shi J

更新日期：2019-06-01 00:00:00

abstract：:This paper reviews the application of flow cytometric techniques to the analysis and quantitation of mixed red cell populations. Such mixtures may arise in a variety of ways, for example: through transplacental hemorrhage during pregnancy or upon delivery; through iatrogenic procedures such as blood transfusion, bone ...

journal_title：Pathology

authors： Nelson M

更新日期：1999-08-01 00:00:00

abstract：:Eight histologically-confirmed cases of clear cell sarcoma of the kidney (CCSK) were studied for possible mutations in the p53 tumor suppressor gene by the immunohistochemical demonstration of mutant p53 proteins using a monoclonal (DO7: Dako) and a polyclonal (AB565: Chemicon) antibody to p53 protein. All cases exhib...

journal_title：Pathology

authors： Cheah PL,Looi LM

更新日期：1996-08-01 00:00:00

abstract：:Forty-six necropsy cases of recurrent pyogenic cholangitis (RPC) among Chinese in Hong Kong were reviewed. Intrahepatic biliary pigment stones or bile sludge were present in all cases and liver abscesses were common (80%). Histologically the early lesion was marked by acute inflammation in portal tracts with frequent ...

journal_title：Pathology

authors： Chou ST,Chan CW

更新日期：1980-07-01 00:00:00

abstract：:A patient initially treated for iron deficiency anemia was later found to have myelofibrosis. She developed increasing splenomegaly and then a mass in the right iliac fossa for which a right hemicolectomy was performed. Histopathology demonstrated extramedullary hemopoiesis in the spleen and cecum. The patient subsequ...

journal_title：Pathology

authors： Sunderland K,Barratt J,Pidcock M

更新日期：1994-01-01 00:00:00

abstract：:Contamination of cell cultures for virus isolation has been increasingly encountered. By reviewing and changing the antimicrobials incorporated in cell culture media, we aim to control this problem. Contaminated cell culture fluids were inoculated for bacterial and fungal isolation, identification and antibacterial su...

journal_title：Pathology

authors： Lo JY,Lim WW,Tam BK,Lai MY

更新日期：1996-11-01 00:00:00

abstract：:Epithelial ovarian neoplasms can be divided into three distinct clinicopathological groups: benign, malignant and borderline tumours. Borderline tumours are less aggressive than epithelial carcinomas, with an indolent clinical course and delayed recurrence. However, a subset of these cases can progress to malignancy a...

journal_title：Pathology

authors： Losi L,Botticelli L,Garagnani L,Fabbiani L,Panini R,Gallo G,Sabbatini R,Maiorana A,Benhattar J

更新日期：2021-02-01 00:00:00

abstract：:We have devised a simple, sensitive quantitative method for the determination of serum methemalbumin. The method uses a modified Allen correction to correct the alpha band of methemalbumin at 623 nm for background turbidity. The technique is robust and is more sensitive than Schumm's test. ...

journal_title：Pathology

authors： Cowley DM,Powell VR

更新日期：1986-07-01 00:00:00

abstract：:Bordetella pertussis, the aetiological agent of whooping cough is routinely diagnosed by polymerase chain reaction (PCR) directed at IS481, an insertion sequence target also found in Bordetella holmesii. Recent reports have suggested that B. holmesii infections can be misdiagnosed as pertussis, which can have a signif...

journal_title：Pathology

authors： Fong W,Timms V,Holmes N,Sintchenko V

更新日期：2018-04-01 00:00:00

abstract：:A rare case of extraskeletal osteosarcoma of the scalp in a 56-year-old woman is described. At presentation she was found to have an 8-cm diameter, tender, firm, exophytic scalp tumor. MRI scan confirmed absence of underlying skeletal origin and showed extension along the subcutaneous plane. The tumor was excised and ...

journal_title：Pathology

authors： Pillay P,Simango S,Govender D

更新日期：2000-05-01 00:00:00

abstract：:The estimation of plasma alanine aminotransferase (ALT) has been proposed as a surrogate test to identify potential non-A, non-B hepatitis carriers in blood donor populations. This report describes an ALT screening procedure which uses wells of microtitration trays as reactant vessels. The method utilizes a rate readi...

journal_title：Pathology

authors： Hyland CA,Douglas R,Mazzocchi R,Young IF

更新日期：1988-07-01 00:00:00

abstract：:The dense fine speckled (DFS) pattern is an antinuclear antibody (ANA) pattern that has recently become of interest. This particular pattern has not been associated with systemic autoimmune rheumatic disorders (SARD) but has been associated with other inflammatory conditions such as interstitial nephritis, autoimmune ...

journal_title：Pathology

authors： Broadfoot A,Sivertsen T,Baumgart K

更新日期：2016-04-01 00:00:00

abstract：AIMS:Hep Par 1 has been described as a specific marker of hepatocellular differentiation and its immunohistochemical use has been suggested as a helpful tool for hepatocellular carcinoma (HCC) diagnosis. Most metastatic liver tumours come from the gastrointestinal tract and usually can be distinguished from HCC only th...

journal_title：Pathology

authors： Villari D,Caruso R,Grosso M,Vitarelli E,Righi M,Barresi G

更新日期：2002-10-01 00:00:00

abstract：:The clinical and laboratory features of a patient with a recently recognized new variant of von Willebrand's disease are presented. The importance of this variant is that it is associated with a clinically significant bleeding diathesis but with a normal skin bleeding time, PTTK, factor VIIIc and platelet aggregation ...

journal_title：Pathology

authors： Wylie B,Gibson J,Uhr E,Kronenberg H

更新日期：1988-01-01 00:00:00

abstract：:Staining for iron showed previously overlooked intra-alveolar siderophages widely distributed in the lungs of two pairs of siblings, all of whom had hospital admissions for apparent life-threatening events (ALTEs) before dying suddenly at home. A mother and babysitter were convicted of their murder and manslaughter re...

journal_title：Pathology

authors： Becroft DM,Lockett BK

更新日期：1997-02-01 00:00:00

abstract：:There are few studies addressing survival of diffuse peritoneal mesotheliomas (DPM).In this study, survival data were obtained retrospectively from 73 patients treated with intended cytoreductive surgery for DPM, with a mean follow-up of 42 months. Mesotheliomas were classified as well differentiated papillary (WDPM, ...

journal_title：Pathology

authors： Liu S,Staats P,Lee M,Alexander HR,Burke AP

更新日期：2014-12-01 00:00:00

abstract：:The monitoring of infliximab drug levels aids in the management of several autoimmune diseases, notably inflammatory bowel disease. Several commercial kits are now available and approved by the Therapeutic Goods Administration (TGA) for the measurement of infliximab levels, but there have been limited verification or ...

journal_title：Pathology

authors： Lee MW,Connor S,Ng W,Toong CM

更新日期：2016-10-01 00:00:00

abstract：:The ultimate goal of defining cancer specific precursors is to facilitate early detection and intervention before the development of invasive malignancy. Unlike other malignancies involving the female genital tract such as cervical or endometrial carcinomas, precursor lesions of ovarian carcinomas have not been well c...

journal_title：Pathology

authors： Lim D,Oliva E

更新日期：2013-04-01 00:00:00

abstract：:Antibodies that bind phospholipid (anti-phospholipid antibodies [APA]) are a focus of major interest to both clinical and laboratory personnel across a variety of disciplines because of the assortment of disorders with which they are reportedly associated. A solid phase assay using cardiolipin as the test phospholipid...

journal_title：Pathology

authors： Favaloro EJ,Silvestrini R,Mohammed A

更新日期：1999-05-01 00:00:00

abstract：:Lysosome-associated membrane protein-1 (LAMP1) has been suggested to play complicated roles in cancer development and metastasis. The aim of this study was to explore the expression of LAMP1 in laryngeal squamous cell carcinoma (LSCC) and investigate the relationship between LAMP1 expression and clinicopathological ch...

journal_title：Pathology

authors： Lu M,Zhu H,Wang X,Zhang D,Xiong L,Zhu J,Mao Y,Qiang J

更新日期：2016-12-01 00:00:00

abstract：:This review will focus on the molecular biology of lymphoproliferative disorders with emphasis on lymphomas. The spectrum of known recurrent gene rearrangements found in lymphomas will be outlined and their relevance to diagnosis and subclassification of disease will be discussed. Finally, a survey of the current tren...

journal_title：Pathology

authors： Catalano A,Iland H

更新日期：2005-12-01 00:00:00

abstract：:The careers and contributions of some of those who have played a major role in the development of knowledge concerning gynaecological pathology are summarised. The emphasis is on workers of prior times beginning with those of the German-speaking school: Carl Ruge, Felix Marchand, Hermann Pfannenstiel, Oskar Frankl, Wa...

journal_title：Pathology

authors： Young RH

更新日期：2007-02-01 00:00:00

abstract：:Mesenchymal stromal cells (MSCs) are a non-homogeneous population of plastic-adherent cells which were initially isolated from post-natal bone marrow. They have the capacity to differentiate to multiple mesodermal lineages including bone, cartilage and adipose tissue. In stringent culture conditions, MSCs can also be ...

journal_title：Pathology

authors： Larsen S,Lewis ID

更新日期：2011-10-01 00:00:00