An overview of the use of flow cytometry in the analysis of mixed red cell populations.

Abstract:

:This paper reviews the application of flow cytometric techniques to the analysis and quantitation of mixed red cell populations. Such mixtures may arise in a variety of ways, for example: through transplacental hemorrhage during pregnancy or upon delivery; through iatrogenic procedures such as blood transfusion, bone marrow or peripheral blood stem cell transplantation; or through disease, when a loss of surface antigen expression may occur due to the expansion of abnormal progenitors lacking the appropriate gene or lacking the ability to translate the product of the gene. Flow cytometry can offer a simple and accurate means of identifying and quantitating mixed red cell populations through detection of antigens specific for either donor or recipient, and in many cases it is possible to distinguish homo- or heterozygous expression of a common antigen. Internal antigens may be accessed after fixation and permeabilisation of the red cells. These latter techniques are relatively new and expand the spectrum of antigenic differences available for the identification of individual species in mixed populations.

journal_name

Pathology

journal_title

Pathology

authors

Nelson M

doi

10.1080/003130299104954

subject

Has Abstract

pub_date

1999-08-01 00:00:00

pages

191-8

issue

3

eissn

0031-3025

issn

1465-3931

journal_volume

31

pub_type

杂志文章,评审
  • Primary small cell carcinoma of the pancreas.

    abstract::A 59 yr old male presented with abdominal pain and jaundice. CT scan showed a tumor in the pancreas with secondaries in the liver, peri-pancreatic lymph nodes, vertebral bone marrow and subcutaneous tissue of the neck together with a cervical lymph node. The patient died after 2 wks and autopsy revealed complete repla...

    journal_title:Pathology

    pub_type: 杂志文章,评审

    doi:10.3109/00313029309066580

    authors: Chetty R,Clark SP,Pitson GA

    更新日期:1993-07-01 00:00:00

  • Xanthogranulomatous cholecystitis and cholecystoduodenal fistula formation associated with total parenteral nutrition in a six year old child.

    abstract::A unique complication of florid xanthogranulomatous cholecystitis with cholecystoduodenal fistula formation is described in a 6 yr old male. The patient, who had a short gut syndrome, had been maintained on lifelong total parenteral nutrition (TPN) following extensive neonatal ischemic bowel necrosis secondary to gast...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313029009086671

    authors: Byard RW,Thorner PS,Cutz E,Filler RM,Durie P

    更新日期:1990-10-01 00:00:00

  • Expression of placental proteins in complete and partial hydatidiform moles.

    abstract::Examination of routinely stained haematoxylin and eosin sections may sometimes prove inadequate in differentiating partial hydatidiform moles (PHM) from complete hydatidiform moles (CHM). While cytogenetic analysis can aid in the distinction, such facilities are not always available. The possibility of using immunohis...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029400169311

    authors: Cheah PL,Looi LM

    更新日期:1994-04-01 00:00:00

  • Role of Ureaplasma urealyticum and Chlamydia trachomatis in lung disease in low birth weight infants.

    abstract::Forty four ventilated premature infants from three Neonatal Intensive Care Units around Melbourne were evaluated prospectively for evidence of Ureaplasma urealyticum and Chlamydia trachomatis infection in the respiratory tract. No C. trachomatis was found and this probably reflects the low prevalence of genital carria...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029600169134

    authors: Garland SM,Bowman ED

    更新日期:1996-08-01 00:00:00

  • Inverse relationships between the expression of MMP-7 and MMP-11 and predictors of poor prognosis of papillary thyroid carcinoma.

    abstract:AIMS:Matrix metalloproteinases (MMPs) have various functions that play roles in carcinoma development. In this study, we investigated the expression of two representative MMPs, MMP-7 and MMP-11, in papillary thyroid carcinomas. METHODS:We immunohistochemically investigated the expression of these MMPs in 196 cases of ...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313020600922496

    authors: Ito Y,Yoshida H,Kakudo K,Nakamura Y,Kuma K,Miyauchi A

    更新日期:2006-10-01 00:00:00

  • Necropsy findings in childhood leukaemia, emphasizing neutropenic enterocolitis and cerebral calcification.

    abstract::In 50 necropsies on leukaemic children, the major cause of death was infection. In patients dying during therapy for induction or reinduction of remission, the most frequent infection was a distinctive neutropenic enterocolitis or typhlitis. This was seen in 46% of the whole series and was a major factor in the death ...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313027609059005

    authors: Moir DH,Bale PM

    更新日期:1976-07-01 00:00:00

  • Reduced CD151 expression is related to advanced tumour stage in urothelial bladder cancer.

    abstract:AIMS:CD151 belongs to the group of tetraspanins and is aberrantly expressed in different tumours and differential expression has been associated with prognosis. The aim of this study was to clarify the relationship of CD151 expression with tumour phenotype and clinical outcome in bladder cancer. METHODS:A bladder canc...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1097/PAT.0b013e32835576ee

    authors: Minner S,De Silva C,Rink M,Dahlem R,Chun F,Fisch M,Höppner W,Wagner W,Bokemeyer C,Terracciano L,Simon R,Sauter G,Wilczak W

    更新日期:2012-08-01 00:00:00

  • Ovarian mucinous tumour arising in mature cystic teratoma and associated with pseudomyxoma peritonei: report of two cases and comparison with ovarian involvement by low-grade appendiceal mucinous tumour.

    abstract:AIMS:It is currently accepted that primary ovarian tumours rarely, if ever, give rise to mucinous ascites/pseudomyxoma peritonei (PMP) which most commonly results from the intra-abdominal spread of an appendiceal mucinous neoplasm. However, primary ovarian mucinous tumours of appendiceal type arising within mature cyst...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313020601024078

    authors: Stewart CJ,Tsukamoto T,Cooke B,Leung YC,Hammond IG

    更新日期:2006-12-01 00:00:00

  • Relations of TGF-beta1 with HIF-1 alpha, GLUT-1 and longer survival of colorectal cancer patients.

    abstract:AIMS AND METHODS:During colorectal carcinogenesis, transforming growth factor beta 1 (TGF-beta1) undergoes a functional change from suppression of cancer cell proliferation to inhibition of T cell mediated anti-cancer immunity. We aimed to evaluate relations among TGF-beta1 and cancer cell survival factors hypoxia indu...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313020802579318

    authors: Sulkowska M,Wincewicz A,Sulkowski S,Koda M,Kanczuga-Koda L

    更新日期:2009-01-01 00:00:00

  • Apoptosis in the human thymus in sudden and delayed death.

    abstract::We counted apoptotic thymic cortical lymphocytes in semi-thin plastic sections of 266 human autopsy thymuses. The decreased patients included in the study were all aged less than 40 yrs and all died within 72 hrs of the onset of symptoms. Based on published data on animal and human material it was anticipated that ind...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029400169261

    authors: Middleton G,Reid LE,Harmon BV

    更新日期:1994-04-01 00:00:00

  • Immunoradiometric assay of plasma lactoferrin.

    abstract::The concentration of lactoferrin, a non-heme iron binding glycoprotein, was determined in more than 1500 EDTA plasma samples by a 2-site solid phase immunoradiometric assay to assess the significance of lactoferrin in plasma and to investigate applications for this assay. The use of commercially available antibody and...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028309061398

    authors: Brown RD,Rickard KA,Kronenberg H

    更新日期:1983-01-01 00:00:00

  • Performance measures for Australian laboratories reporting cervical cytology: a decade of data 1998-2008.

    abstract:AIM:Performance measures for Australian laboratories reporting cervical cytology are a set of quantifiable measures relating to the profile and accuracy of reporting. This study reviews aggregate data collected over the ten years in which participation in the performance measures has been mandatory. METHODS:Laboratori...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313025.2010.520308

    authors: Shield PW,Finnimore J,Cummings M,Wright RG

    更新日期:2010-12-01 00:00:00

  • Effect on organism recovery rate from BacT/Alert blood cultures with reduced incubation period.

    abstract::This retrospective study evaluated 15,377 sets of BacT/Alert blood cultures to determine incubation time for blood cultures. Ninety-six per cent (1476) of total isolates signalled positive within five days and 56 isolates turned positive in five to seven days. Of the 56 organisms recovered between five and seven days,...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029800169176

    authors: Mukerjee C,Heron LG,Varettas K

    更新日期:1998-05-01 00:00:00

  • INI1 immunohistochemical expression in glioblastoma: correlation with MGMT gene promoter methylation status and patient survival.

    abstract:AIMS:INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ). METHODS:INI1 was determined by immunohistochemistry and MGMT by methylation-specific PCR. RESULTS...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1097/PAT.0b013e328340bb26

    authors: Zunarelli E,Bigiani N,Sartori G,Migaldi M,Sgambato A,Maiorana A

    更新日期:2011-01-01 00:00:00

  • Lymphoplasmacytic lymphoma and Waldenström macroglobulinaemia: clinicopathological features and differential diagnosis.

    abstract::Lymphoplasmacytic lymphoma (LPL) represents a distinct type of mature B-cell lymphoma with a substantial subset of cases being associated with Waldenström macroglobulinaemia (WM), defined as primarily bone marrow involvement and the presence of an IgM monoclonal paraprotein. MYD88 L265P mutation, although not specific...

    journal_title:Pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pathol.2019.09.009

    authors: Wang W,Lin P

    更新日期:2020-01-01 00:00:00

  • Reliability of the porphobilinogen screening assay.

    abstract::A survey conducted by the Australian Association of Clinical Biochemists Porphyrin Working Party on urinary porphobilinogen screening showed good sensitivity (75-97.5%). This is contrary to reports in the literature and to our own observations. We therefore assessed a widely used screening method (Watson-Schwartz) and...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313029009086660

    authors: Buttery JE,Carrera AM,Pannall PR

    更新日期:1990-10-01 00:00:00

  • Gentamicin nephropathy in a neonate.

    abstract::The clinical and autopsy findings in a premature baby who died of acute renal failure after therapy with gentamicin (5 mg/kg/day) and penicillin are presented. The serum gentamicin concentration had reached toxic levels when anuria developed. Numerous periodic acid Schiff (PAS) positive, diastase resistant cytoplasmic...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028509105512

    authors: Chan KW,Ng WL

    更新日期:1985-07-01 00:00:00

  • Mitral and aortic valve abnormalities in a patient with fibrodysplasia ossificans progressiva.

    abstract::A 36-yr-old female with a 20-yr history of fibrodysplasia ossificans progressiva (FOP) died as the result of ruptured gastric ulcers. The patient had been treated with disodium ethane-l-hydroxy-1, 1-diphosphonate (EHDP). Post mortem there was thickening of the aortic valve cusps and mitral valve leaflets as well as sh...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028309083514

    authors: Jaworski RC,Gibson M

    更新日期:1983-07-01 00:00:00

  • Rhabdoid tumour: a malignancy of early childhood with variable primary site, histology and clinical behaviour.

    abstract:AIMS:To correlate the immunostaining for INI1 protein and mutations in INI1 gene in possible rhabdoid tumours (RT) and atypical teratoid/rhabdoid tumours (AT/RT) seen at the Royal Children's Hospital in the last 10 years, and to study the clinicopathological features of those patients with negative nuclear staining. M...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313020802436451

    authors: Wu X,Dagar V,Algar E,Muscat A,Bandopadhayay P,Ashley D,Wo Chow C

    更新日期:2008-12-01 00:00:00

  • Benign nerve sheath tumors: a light microscopic, electron microscopic and immunohistochemical study of 102 cases.

    abstract::One hundred and two cases of benign nerve sheath tumors (NSTs) were studied with a combined approach using routine light microscopy (LM), immunohistochemistry (IH) for myelin basic protein (MBP) and S-100 protein as well as transmission electron microscopy (TEM) with the aim of obtaining greater insight into the true ...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313029009086659

    authors: Sharma S,Sarkar C,Mathur M,Dinda AK,Roy S

    更新日期:1990-10-01 00:00:00

  • Role of the renal sympathetic nervous system in mediating renal ischaemic injury-induced reductions in renal haemodynamic and excretory functions.

    abstract:AIM:We investigated the role of renal sympathetic innervation in the deterioration of renal haemodynamic and excretory functions during the early post-ischaemic phase of renal ischaemia/reperfusion injury. METHODS:Anaesthetised male Sprague-Dawley rats were subjected to unilateral renal ischaemia by clamping the left ...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313021003631304

    authors: Salman IM,Ameer OZ,Sattar MA,Abdullah NA,Yam MF,Najim HS,Khan AH,Johns EJ

    更新日期:2010-04-01 00:00:00

  • Inhibitory substances in horse sera used in the preparation of microbiological culture media.

    abstract::The failure of N. gonorrhoeae to grow on isolation media was found to be due to inhibitory substances present in commercially available horse sera. Subsequent investigations indicated that the inhibitory action of the horse serum may have been due to antibodies to N. gonorrhoeae, H. influenzae, H. parainfluenzae and b...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028409068534

    authors: Mugg PA,Hill A

    更新日期:1984-07-01 00:00:00

  • Thermolabile methyltetrahydrofolate reductase associated with unusual venous and arterial thromboses.

    abstract::We report a patient with unusual venous and arterial thromboses in association with the common thermolabile methyltetrahydrofolate (MTHFR) variant. The patient responded directly to folate supplementation. To our knowledge, this is the first report describing hyperhomocysteinemia in association with this type of throm...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/003130299105502

    authors: Hall TN,Ramakrishnan LL,Leahy MF

    更新日期:1999-02-01 00:00:00

  • Inflammatory pseudotumor of epididymis and Epstein-Barr virus: a study of two cases.

    abstract::Inflammatory pseudotumor (IP) is an uncommon tumor-like lesion of unknown etiology. Two cases of IP of the epididymis were identified in our hospital file. Having read a recent report on finding Epstein-Barr virus (EBV) in some cases of IP in lymph node, spleen and liver, the two cases of epididymal IP were tested for...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029700169664

    authors: Chan KW,Chan KL,Lam KY

    更新日期:1997-02-01 00:00:00

  • Experimental autoimmune glomerulonephritis in the rat. II. A histopathological and fine structural study.

    abstract::Human glomerular basement membrane (GBM) emulsified in Freund's complete adjuvant was injected into 16 Holtzman rats. Eleven (69%) of them subsequently developed glomerulonephritis. This disease was characterized by glomerular changes which included focal lobular hypercellularity due to localized hyperplasia of intrac...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313027609094437

    authors: McCausland IP,Herdson PB,Gavin JB

    更新日期:1976-04-01 00:00:00

  • Murine chronic tubulointerstitial nephritis: induction by human uveitis mycoplasma-like organisms.

    abstract::Mycoplasma-like organisms (MLO) are non-cultivated intracellular cell wall deficient pathogenic bacteria with a distinctive ultrastructural appearance. Diagnosis of MLO disease rests on finding the organisms in parasitized cells using a transmission electron microscope. MLO are a well studied cause of transmissible ch...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029400169192

    authors: Johnson L,Wirostko E,Wirostko B

    更新日期:1994-10-01 00:00:00

  • Benign bone tumours in Western Australia, 1972-1996.

    abstract:AIMS:To review the benign bone tumours accessioned by the Bone Tumour Registry (BTR) of Western Australia (WA) during the years 1972-1996 and to determine the incidence of the more common types. METHODS:Information was extracted from the Registry database using 58 selected fields. RESULTS:During the 25 year period, 8...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313020701684334

    authors: Blackwell JB,Curnow MN

    更新日期:2007-12-01 00:00:00

  • Diagnostic performance of CD66c in lung adenocarcinoma-associated malignant pleural effusion: comparison with CEA, CA 19-9, and CYFRA 21-1.

    abstract::Various tumour markers have been evaluated in malignant pleural effusions, but not CD66c. This study evaluated the diagnostic ability of CD66c in lung adenocarcinoma-associated malignant pleural effusions (LA-MPEs) and compared it with other known tumour markers. Forty-seven cases of LA-MPE and 52 cases of benign pleu...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1097/PAT.0000000000000215

    authors: Son SM,Han HS,An JY,Choe KH,Lee KM,Lee KH,Kim SS,Lee YM,Lee HC,Song HG,Lee OJ

    更新日期:2015-02-01 00:00:00

  • Malignant solitary fibrous tumour of the prostate: four cases emphasising significant histological and immunophenotypical overlap with sarcomatoid carcinoma.

    abstract::Solitary fibrous tumour (SFT) is well-described in the urinary tract, but malignant examples are rare. We studied our experience with high grade malignant SFT of the prostate to address the degree of histological and immunophenotypical overlap with sarcomatoid carcinoma and prostatic stromal sarcoma. Four cases were i...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1016/j.pathol.2020.06.004

    authors: Bakhshwin A,Berry RS,Cox RM,Li R,Reynolds JP,Rubin BP,McKenney JK

    更新日期:2020-10-01 00:00:00

  • Review of 253 cases of significant pathology in 7,910 cholecystectomies in Hong Kong.

    abstract::A retrospective study of gallbladders submitted as surgical specimens over a period of fifteen years (1972-1986) was performed in the Department of Pathology, Queen Mary Hospital, Hong Kong. Seven thousand nine hundred and ten gallbladders were examined. A total of 253 more unusual and significant pathological lesions...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028809085191

    authors: Chan KW

    更新日期:1988-01-01 00:00:00