Abstract:
:A retrospective study of gallbladders submitted as surgical specimens over a period of fifteen years (1972-1986) was performed in the Department of Pathology, Queen Mary Hospital, Hong Kong. Seven thousand nine hundred and ten gallbladders were examined. A total of 253 more unusual and significant pathological lesions were recorded. The diagnoses made in these cases, in descending order of frequency, were primary carcinoma, metastatic carcinoma, adenoma, clonorchiasis and others. In 76 gallbladders clinically significant pathology was first discovered on pathological examination.
journal_name
Pathologyjournal_title
Pathologyauthors
Chan KWdoi
10.3109/00313028809085191subject
Has Abstractpub_date
1988-01-01 00:00:00pages
20-3issue
1eissn
0031-3025issn
1465-3931journal_volume
20pub_type
杂志文章相关文献
PATHOLOGY文献大全abstract::The current public health emergency surrounding the COVID-19 pandemic, that is the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in thousands of cases in Australia since 25 January 2020 when the first case was diagnosed. This emerging virus presents particular hazards to ...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2020.09.006
更新日期:2020-12-01 00:00:00
abstract::The aims of this study were to investigate the immunohistochemical expression and potential prognostic significance of putative cancer stems cell markers ALDH1, EZH2 and SOX2 in prostate cancer.A total of 142 consecutive radical prostatectomies submitted to one laboratory with a diagnosis of prostatic adenocarcinoma b...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1097/PAT.0000000000000325
更新日期:2015-12-01 00:00:00
abstract::Rapid rescreening was established in our laboratory in 1995, following the publication of several studies indicating improved sensitivity for the detection of abnormalities in cervical smears. During the study period, 285,841 negative smears (representing 89.09% of the total workload) were rapidly rescreened. A total ...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/003130299104765
更新日期:1999-11-01 00:00:00
abstract::An unusual case of gliomatosis cerebri in a 37 yr-old man is reported. He presented with a variable clinical picture. Mental changes, brain stem signs, cerebellar signs and rise in intracranial pressure were the constant findings. The postmortem findings are described and the available literature is reviewed. ...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028509063740
更新日期:1985-01-01 00:00:00
abstract::In 50 necropsies on leukaemic children, the major cause of death was infection. In patients dying during therapy for induction or reinduction of remission, the most frequent infection was a distinctive neutropenic enterocolitis or typhlitis. This was seen in 46% of the whole series and was a major factor in the death ...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313027609059005
更新日期:1976-07-01 00:00:00
abstract::In order to determine whether routine culturing for Clostridium difficile was warranted or whether culturing a selected group of patients was adequate, we conducted a prospective trial of culturing all stool specimens for C. difficile. A total of 408 specimens from 297 patients was studied. Two hundred and eighteen st...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028409068530
更新日期:1984-07-01 00:00:00
abstract::Langerhans cell histiocytosis (LCH) is currently regarded as a myeloid neoplasm, with remarkably broad clinical spectrum, ranging from isolated skin or bone lesions to a disseminated disease that can involve nearly any organ. LCH is generally regarded as a sporadic disease that occurs predominantly in the paediatric p...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.1097/PAT.0000000000000256
更新日期:2015-06-01 00:00:00
abstract::A fatal case of multiple sulfatase deficiency in a 10-year-old girl is reported. In this rare disease, which is inherited as an autosomal recessive, features of metachromatic leukodystrophy and of mucopolysaccharidoses occur together. The white matter suffers progressive destruction with sulfatides accumulating in mac...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028809059509
更新日期:1988-07-01 00:00:00
abstract::Epithelial ovarian neoplasms can be divided into three distinct clinicopathological groups: benign, malignant and borderline tumours. Borderline tumours are less aggressive than epithelial carcinomas, with an indolent clinical course and delayed recurrence. However, a subset of these cases can progress to malignancy a...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2020.07.010
更新日期:2021-02-01 00:00:00
abstract::Papillary proliferations of the endometrium (PPEs) are uncommon lesions that are often associated with endometrial polyps. PPEs occasionally precede or co-exist with atypical endometrial hyperplasia or adenocarcinoma, but their pathogenesis and relationship to endometrial neoplasia is uncertain. In the present study 1...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2017.10.013
更新日期:2018-04-01 00:00:00
abstract::The main controversy about nerve sheath tumors (NSTs) has been their histogenesis. A Schwann cell origin has been proposed by many investigators for both schwannomas and neurofibromas. However Erlandson and Woodruff observed that while schwannomas appeared to be composed predominantly of Schwann cells, neurofibromas c...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313029400169051
更新日期:1994-01-01 00:00:00
abstract::Recent controversies both in Australia and overseas have focused public attention on autopsy practice. It has become apparent that there is an increasing expectation amongst the public for more detailed information concerning autopsy procedures and, in particular, tissue retention. This article attempts to review the ...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.1080/00313020120105660
更新日期:2002-02-01 00:00:00
abstract::Neuroendocrine (NE) tumours are uncommon in the gynecological tract. In addition to their histological features, what defines NE carcinoma is the expression of markers such as chromogranin, synaptophysin and neural cell adhesion molecule (CD56) by immunohistochemistry (IHC). Although limited data have demonstrated tha...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2019.02.003
更新日期:2019-06-01 00:00:00
abstract::The cancer stem cell hypothesis suggests that malignant tumours may arise from a limited number of specialised cells possessing the key 'stem' properties of self-renewal and the ability to produce differentiated progeny. Such cells purportedly constitute a small fraction of most tumours but have greater potential to p...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.3109/00313020903488773
更新日期:2010-02-01 00:00:00
abstract:AIMS:Nuclear factor-kappa B (NF-kappaB) activation has been recognised as an important mechanism in the development of cancers. However, expression status of NF-kappaB-related proteins in oesophageal squamous cell carcinoma (ESCC) tissues is largely unknown. In this study, we analysed expressions of NF-kappaB members (...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313020903257756
更新日期:2009-01-01 00:00:00
abstract:AIMS:Biochemical analysis of glucose and ketones in the vitreous humour obtained at post-mortem examination is representative of the levels in the blood prior to death. Elevated levels can be indicative of conditions including diabetic ketoacidosis, which can be a cause for unexpected death. A rapid screening test for ...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1097/PAT.0b013e3283650b93
更新日期:2013-10-01 00:00:00
abstract:AIMS:Sirtuin1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent deacetylase. Recently, some studies have suggested that SIRT1 could be over-expressed in breast, prostate and colon cancers and up-regulated SIRT1 inactivates p53 by deacetylation. Therefore, we investigated the prevalence and the prognostic impact ...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313020902884451
更新日期:2009-01-01 00:00:00
abstract::Certain diagnoses in dermatopathology have significant implications for patient management and on occasion appropriate clinical care may be facilitated by a phone call from the reporting dermatopathologist to the referring doctor. Whether this is appropriate depends on a number of factors. The concept of 'critical dia...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2017.10.015
更新日期:2018-04-01 00:00:00
abstract::While localised prostate cancer can be cured by local treatment, 'high-risk' prostate cancer often progresses to castration resistant disease and remains incurable with a dismal prognosis. In recent years, technical advances and development of novel methodologies have largely contributed to a better understanding of u...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.1016/j.pathol.2020.10.003
更新日期:2021-01-01 00:00:00
abstract::Sera from 82 patients with acute or chronic hepatitis and 40 chronic carriers of hepatitis B were examined by ELISA and immunoblotting for reactivity with the glycolytic enzyme aldolase. The results of the ELISA tests, expressed as a percentage of a positive control, were compared to those obtained with sera from 39 p...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028709103881
更新日期:1987-10-01 00:00:00
abstract::Lymph node metastasis (LNM) is an important factor for predicting prognosis and selecting appropriate treatment in early gastric cancers (EGCs). We investigated the histopathological and microenvironmental predictors of LNM in EGCs. We retrieved 43 cases of EGC without LNM and 59 cases with LNM. Clinicopathological va...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2017.06.003
更新日期:2017-10-01 00:00:00
abstract::Solitary fibrous tumour (SFT) is well-described in the urinary tract, but malignant examples are rare. We studied our experience with high grade malignant SFT of the prostate to address the degree of histological and immunophenotypical overlap with sarcomatoid carcinoma and prostatic stromal sarcoma. Four cases were i...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2020.06.004
更新日期:2020-10-01 00:00:00
abstract::Deregulation of the receptors of TNF-related apoptosis inducing ligand (TRAIL) has been reported in various cancers. In an effort to define the role of these receptors we profiled their expression in gallbladder cancer (GBC) and explored their clinical significance. Expression of TRAIL receptors' mRNA in GBC was analy...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1016/j.pathol.2019.12.001
更新日期:2020-04-01 00:00:00
abstract::Seven cases of lower respiratory tract infection due to Corynebacterium pseudodiphtheriticum are described. Lower respiratory tract infections with C. pseudodiphtheriticum in immunocompetent patients are usually associated with pre-existing chronic pulmonary disease, and are sometimes associated with endotracheal intu...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313029400169721
更新日期:1994-07-01 00:00:00
abstract:AIMS:We assessed the expression of ALDH1 and EZH2, cancer stem cell (CSC) related markers, in triple negative and basal-like breast cancers, investigating their association with clinicopathological features and outcome. METHODS:Clinicopathological data were obtained from 140 cases of triple negative breast cancer. A t...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1097/PAT.0b013e3283534bcb
更新日期:2012-06-01 00:00:00
abstract::We report a patient with unusual venous and arterial thromboses in association with the common thermolabile methyltetrahydrofolate (MTHFR) variant. The patient responded directly to folate supplementation. To our knowledge, this is the first report describing hyperhomocysteinemia in association with this type of throm...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/003130299105502
更新日期:1999-02-01 00:00:00
abstract:AIMS:To examine the impact of microwave (MW) tissue processing on turnaround times (TATs) in a routine diagnostic laboratory. METHODS:A retrospective review of TATs for tissue processing (specimen receipt to completion of H&E-stained section) and pathologists' report generation (receipt of stained section to validatio...
journal_title:Pathology
pub_type: 杂志文章
doi:10.1080/00313020410001721564
更新日期:2004-08-01 00:00:00
abstract:AIMS:This study was undertaken to investigate the genetic factors underlying the development of multifocality and phenotypic diversity in multifocal papillary thyroid carcinoma (mPTC). METHODS:Loss of heterozygosity (LOH) and BRAF(V600E) mutation status were analysed in a total of 55 individual tumour foci from 18 cas...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313025.2010.508780
更新日期:2010-01-01 00:00:00
abstract::Proliferation of isolated hepatocytes in long-term splenic implants was assessed by flash labelling with a 1 pulse of tritiated thymidine (3H TdR). Cell kinetics showed that the basal labelling index was 0.9% which was greater than normal non-regenerating liver. Twenty four hours following partial hepatectomy the labe...
journal_title:Pathology
pub_type: 杂志文章
doi:10.3109/00313028709065131
更新日期:1987-01-01 00:00:00
abstract::Plexiform leiomyomas of the uterus are incidental findings in hysterectomy specimens. Histogenetically, these rare tumors are classified as a variant of epithelioid leiomyomas. Most of the plexiform leiomyomas reported range in size from microscopically small lesions to less than 1 cm in largest diameter, and they mac...
journal_title:Pathology
pub_type: 杂志文章,评审
doi:10.1080/003130299105197
更新日期:1999-08-01 00:00:00