NF-kappaB signalling proteins p50/p105, p52/p100, RelA, and IKKepsilon are over-expressed in oesophageal squamous cell carcinomas.

abstract：:The aim of the present study is to describe the histological and mutational characteristics of a series of both large and small bowel adenocarcinomas in patients with Crohn's disease from a tertiary referral centre of inflammatory bowel disease. Bowel adenocarcinoma was diagnosed in 11 (1.7%) of 660 consecutive patien...

journal_title：Pathology

authors： Malvi D,Vasuri F,Mattioli B,Gruppioni E,Fiorentino M,Gionchetti P,Grigioni WF,Poggioli G,D'Errico-Grigioni A

更新日期：2014-08-01 00:00:00

abstract：AIMS:In our previous studies, comparative proteomics demonstrated that lactate dehydrogenase B subunit (LDH-B) is down-regulated in high grade compared to non-high grade urinary bladder urothelial carcinoma (UBUC). However, this finding has not been validated by clinical cohort investigation. Therefore, in the present ...

journal_title：Pathology

authors： Liao AC,Li CF,Shen KH,Chien LH,Huang HY,Wu TF

更新日期：2011-12-01 00:00:00

abstract：:A 5-year-old Chinese boy had dull pain in his right knee for about one year. An intraosseous osteolytic lesion in the metaphysis of the right lower femur was curetted. The diagnosis of desmoplastic fibroma, possibly the first in a Hong Kong Chinese, was based on the clinical, radiological and histological findings. Ab...

journal_title：Pathology

authors： Chan KW,Pun WK,Choi CH

更新日期：1987-04-01 00:00:00

abstract：:A novel grading system based on the counting of poorly differentiated clusters (PDC) of neoplastic cells at the invasive margin and in the tumour stroma was recently introduced among the histological parameters predictive of adverse clinical outcome in colorectal cancer (CRC). The aim of this study was to correlate th...

journal_title：Pathology

authors： Barresi V,Bonetti LR,Bettelli S

更新日期：2015-10-01 00:00:00

abstract：AIMS:It is currently accepted that primary ovarian tumours rarely, if ever, give rise to mucinous ascites/pseudomyxoma peritonei (PMP) which most commonly results from the intra-abdominal spread of an appendiceal mucinous neoplasm. However, primary ovarian mucinous tumours of appendiceal type arising within mature cyst...

journal_title：Pathology

authors： Stewart CJ,Tsukamoto T,Cooke B,Leung YC,Hammond IG

更新日期：2006-12-01 00:00:00

abstract：:Lymph node metastasis (LNM) is an important factor for predicting prognosis and selecting appropriate treatment in early gastric cancers (EGCs). We investigated the histopathological and microenvironmental predictors of LNM in EGCs. We retrieved 43 cases of EGC without LNM and 59 cases with LNM. Clinicopathological va...

journal_title：Pathology

authors： Kim JY,Kim CH,Lee Y,Lee JH,Chae YS

更新日期：2017-10-01 00:00:00

abstract：:We present the clinical and postmortem findings in seven adults (four females and three males), who died with dissection of the coronary arteries. The median age was 56 years. Five of the coronary artery dissections (CADs) were spontaneous and two followed trauma: one a motor vehicle accident, the other occurred durin...

journal_title：Pathology

authors： Mulvany NJ,Ranson DL,Pilbeam MC

更新日期：2001-08-01 00:00:00

abstract：AIM:1) To determine the prevalence of hepatitis B in Sydney autopsies and 2) to determine the relationship between seroprevalence, hepatitis B risk factors and histological changes in the liver. METHODS:One hundred autopsy subjects were studied for evidence of past or present hepatitis B infection, using RIA to detect...

journal_title：Pathology

authors： Ashwell MJ,Cossart YE

更新日期：1995-01-01 00:00:00

abstract：:Associations between histologically defined proliferative, but benign, epithelial disorders of the breast and risk factors for breast carcinoma were examined in 568 patients whose breast biopsies were submitted consecutively to the laboratory. Some disorders were associated with multiparity. Blunt duct adenosis was as...

journal_title：Pathology

authors： Cook MG,Rohan TE

更新日期：1991-10-01 00:00:00

abstract：:Human papillomavirus (HPV) is a common viral infection of squamous epithelial tissues, but its importance has only recently been recognised by the medical community. HPVs are now realised to consist of many genotypes and are associated with a diverse spectrum of clinical manifestations. Within the genital tract, some ...

journal_title：Pathology

authors： Garland SM

更新日期：2002-06-01 00:00:00

abstract：:The main controversy about nerve sheath tumors (NSTs) has been their histogenesis. A Schwann cell origin has been proposed by many investigators for both schwannomas and neurofibromas. However Erlandson and Woodruff observed that while schwannomas appeared to be composed predominantly of Schwann cells, neurofibromas c...

journal_title：Pathology

authors： Kharbanda K,Dinda AK,Sarkar C,Karak AK,Mathur M,Roy S

更新日期：1994-01-01 00:00:00

abstract：:The cell surface markers of 75 cases of non-Hodgkin's lymphoma were studied on cryostat sections using a panel of monoclonal antibodies. Forty-nine cases (65.3%) were found to express a B-cell phenotype, 23 cases (30.7%) a T-cell phenotype, 1 case (1.3%) a histiocytic phenotype and 2 cases (2.7%) no demonstrable surfa...

journal_title：Pathology

authors： Ng CS,Chan JK,Lo ST,Poon YF

更新日期：1986-10-01 00:00:00

abstract：AIM:The purpose of this study was to elucidate the clonality of fibrous dysplasia based on X-chromosome inactivation mosaicism and polymorphism in female somatic cells at the phosphoglycerate kinase (PGK) and androgen receptor (AR) loci using microdissection technology. MATERIALS AND METHODS:Nine patients with fibrous...

journal_title：Pathology

authors： Gong L,Zhang W,Su Q

更新日期：2008-06-01 00:00:00

abstract：:A total of 52 of 238 patients (22%) with non-Hodgkin's lymphoma presented with disease in a primary extranodal site. The gastrointestinal tract was the commonest site involved (50%) and diffuse large cell was the commonest histological sub-type of the lymphoma (64%). Survivorship analysis of these patients, treated pr...

journal_title：Pathology

authors： Manoharan A,Smart RC,Pitney WR

更新日期：1986-10-01 00:00:00

abstract：:We report a rare case of bilateral primary seminal vesicle carcinoma in a 73 yr old Australian man. To our knowledge this case report is the 48th histologically confirmed case of primary seminal vesicle neoplasia and only the fourth reported case of primary bilateral seminal vesicle carcinoma. Macroscopically the tumo...

journal_title：Pathology

authors： Ormsby AH,Haskell R,Ruthven SE,Mylne GE

更新日期：1996-05-01 00:00:00

abstract：:An enzyme-immunoassay has been developed for the detection of myoglobin in human serum and urine which is specific, accurate, precise, and has a sensitivity of 3 ng/ml. When compared with radioimmunoassay, the enzyme-immunoassay gives markedly similar results. Sera from normal adults had a myoglobin concentration in t...

journal_title：Pathology

authors： Cloonan MJ,Bishop GA,Wilton-Smith PD,Carter IW,Allan RM,Wilcken DE

更新日期：1979-10-01 00:00:00

abstract：:The in vitro activity of cefepime was compared to that of a range of other broad-spectrum agents, using a gradient diffusion MIC method, against 995 recent clinical isolates of Enterobacteriaceae, Pseudomonas aeruginosa, other nonfermentative gram-negative bacilli, staphylococci (except oxacillin-resistant Staphylococ...

journal_title：Pathology

authors： Bell JM,Turnidge JD,Cefepime Study Group.

更新日期：2001-02-01 00:00:00

abstract：AIMS:Predicting the clinical behaviour of gastrointestinal stromal tumours (GISTs) is difficult and criteria delineating benign from malignant cases are not firmly established. The aims of this study were to define the clinicopathological and molecular features of 66 GISTs, and to determine whether any specific paramet...

journal_title：Pathology

authors： Koay MH,Goh YW,Iacopetta B,Grieu F,Segal A,Sterrett GF,Platten M,Spagnolo DV

更新日期：2005-02-01 00:00:00

abstract：:Apoptosis in the myocardium is complex and often difficult to recognise. Myocyte apoptosis is scattered across the myocardial wall and is restricted to individual cells. In the present study, we describe the amount of apoptosis in 50 endomyocardial biopsies taken from 50 patients with dilated cardiomyopathy, in 14 hea...

journal_title：Pathology

authors： Kavantzas NG,Lazaris AC,Agapitos EV,Nanas J,Davaris PS

更新日期：2000-08-01 00:00:00

abstract：:The most significant task of the pathologist examining a fetal death is, if possible, the provision of an explanation for the event, which will allow the clinical attendants to counsel the family in an informed and relevant manner. In some cases, no adequate explanation will be possible, though many conditions will be...

journal_title：Pathology

authors： Smith NM

更新日期：2000-05-01 00:00:00

abstract：:The monitoring of infliximab drug levels aids in the management of several autoimmune diseases, notably inflammatory bowel disease. Several commercial kits are now available and approved by the Therapeutic Goods Administration (TGA) for the measurement of infliximab levels, but there have been limited verification or ...

journal_title：Pathology

authors： Lee MW,Connor S,Ng W,Toong CM

更新日期：2016-10-01 00:00:00

abstract：:Gram negative anaerobic organisms are important pathogens in a range of clinical infections, and susceptibility testing is not commonly performed in the microbiology laboratory. We performed anaerobic susceptibility testing on 70 clinically relevant Gram negative anaerobes isolated from routine cultures in a busy diag...

journal_title：Pathology

authors： Hughes C,Ashhurst-Smith C,Ferguson JK

更新日期：2018-06-01 00:00:00

abstract：:A "collision" tumor between a serous papillary adenocarcinoma and a steroid cell tumor of the ovary is described. No similar combination has been reported in the literature. The steroid cell component secreted testosterone, resulted in considerable virilization of the patient, and appears to have preceded the carcinom...

journal_title：Pathology

authors： Nirenberg A,Ostör AG,Quinn MA

更新日期：1992-04-01 00:00:00

abstract：AIMS:Recent study indicates that the binding of caveolin-1 (CAV1), the essential constituent of caveolae, to endothelial nitric oxide synthase (eNOS) prevents nitric oxide (NO) production in cirrhotic human liver. However, their interplay in hepatocellular carcinoma (HCC) remains undetermined. METHODS:Paraffin-embedde...

journal_title：Pathology

authors： Yang SF,Yang JY,Huang CH,Wang SN,Lu CP,Tsai CJ,Chai CY,Yeh YT

更新日期：2010-01-01 00:00:00

abstract：AIM:It is routine practice to prolong the incubation period of blood cultures from patients with suspected subacute bacterial endocarditis (SBE) or fungal infection. The protocol in this laboratory required 28 days incubation with weekly subcultures. Following the introduction of automated continuously monitored blood ...

journal_title：Pathology

authors： Varettas K,Taylor PC,Mukerjee C

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:Detection of the V600E hotspot mutation in BRAF oncogene is extremely useful for the screening of hereditary non-polyposis colorectal cancer (Lynch's syndrome) and for the prediction of sensitivity to MEK inhibitors. Here we describe a method for detecting this mutation based upon pyrosequencing technology...

journal_title：Pathology

authors： Tan YH,Liu Y,Eu KW,Ang PW,Li WQ,Salto-Tellez M,Iacopetta B,Soong R

更新日期：2008-04-01 00:00:00

abstract：AIMS:Activation of β-catenin has been identified as a possible mechanism for the development of nephroblastomas. In our study we investigated whether this activation occurs already in precursor lesions of nephroblastomas, called nephrogenic rests (NRs). Inactivation of the adenomatous polyposis coli (APC) protein is an...

journal_title：Pathology

authors： Grill C,Sunitsch S,Hatz M,Hauser-Kronberger C,Leuschner I,Hoefler G,Guertl B

更新日期：2011-12-01 00:00:00

abstract：:Results are presented of a study comparing cerbB2 (neu or Her2) expression as assessed immunohistochemically in breast neoplasia using a panel of 6 commercially available antibodies. The antibodies were examined utilizing conventional formalin fixed paraffin embedded tissue, and compared with molecular analysis of gen...

journal_title：Pathology

authors： Busmanis I,Feleppa F,Jones A,McGrath KM,Reed R,Collins J,Russell I,Begley CG

更新日期：1994-07-01 00:00:00

abstract：:Four hundred and ten thyroid nodules, 127 breast lumps and 43 lymph nodes were sampled and analyzed to compare the classical aspiration (ASP) technique with the non aspiration needle jab (NASP) technique. The adequacy of cellularity, significant blood staining and the discomfort felt by the patient were assessed and s...

journal_title：Pathology

authors： Kumarasinghe MP,Sheriffdeen AH

更新日期：1995-10-01 00:00:00

abstract：:A unique complication of florid xanthogranulomatous cholecystitis with cholecystoduodenal fistula formation is described in a 6 yr old male. The patient, who had a short gut syndrome, had been maintained on lifelong total parenteral nutrition (TPN) following extensive neonatal ischemic bowel necrosis secondary to gast...

journal_title：Pathology

authors： Byard RW,Thorner PS,Cutz E,Filler RM,Durie P

更新日期：1990-10-01 00:00:00