Lymphoplasmacytic lymphoma and Waldenström macroglobulinaemia: clinicopathological features and differential diagnosis.

abstract：:Lymph node metastasis (LNM) is an important factor for predicting prognosis and selecting appropriate treatment in early gastric cancers (EGCs). We investigated the histopathological and microenvironmental predictors of LNM in EGCs. We retrieved 43 cases of EGC without LNM and 59 cases with LNM. Clinicopathological va...

journal_title：Pathology

authors： Kim JY,Kim CH,Lee Y,Lee JH,Chae YS

更新日期：2017-10-01 00:00:00

abstract：AIMS:The roles of tumour suppressor genes: adenomatous polyposis coli (APC) and E-cadherin (CDH1) were investigated in clear cell renal cell carcinoma. METHODS:Forty-five human clear cell renal cell carcinomas were tested for APC gene instability by polymerase chain reaction/loss of heterozygosity using the restrictio...

journal_title：Pathology

authors： Pećina-SLaus N,Gall-TroSelj K,SLaus M,Radić K,NikuSeva-Martić T,Pavelić K

更新日期：2004-04-01 00:00:00

abstract：:A genetic variant of antithrombin with impaired heparin cofactor activity was identified in 4 members of a French family. Both the variant and normal antithrombin component were purified by affinity chromatography on heparin Sepharose. Reverse phase peptide mapping revealed a single altered peak when tryptic digests o...

journal_title：Pathology

authors： Brennan SO,Borg JY,Shaw GJ,Caen J,George PM

更新日期：1991-01-01 00:00:00

abstract：:Neuroendocrine (NE) tumours are uncommon in the gynecological tract. In addition to their histological features, what defines NE carcinoma is the expression of markers such as chromogranin, synaptophysin and neural cell adhesion molecule (CD56) by immunohistochemistry (IHC). Although limited data have demonstrated tha...

journal_title：Pathology

authors： Moritz AW,Schlumbrecht MP,Nadji M,Pinto A

更新日期：2019-06-01 00:00:00

abstract：AIMS:Activation of nuclear factor-kappa B (NF-kappaB) signalling is considered a crucial mechanism in the development of cancers. Caspase-associated recruitment domain 6 (CARD6) is a protein that activates NF-kappaB signalling evoked by RIP1, RIP2, Bcl-10 and MEKK. In this study, we analysed tissue expression of CARD6 ...

journal_title：Pathology

authors： Kim SS,Ahn CH,Kang MR,Kim YR,Kim HS,Yoo NJ,Lee SH

更新日期：2010-01-01 00:00:00

abstract：:An improved one-stage method for accurate assays of factor VIII combines highly reproducible end points with elimination of temporal drift and of subjective factors involved in graphic analysis. Activated deficient plasma substrate (ADPS) is used as a single reagent for parallel tests. The assays can be performed manu...

journal_title：Pathology

authors： Margolis J

更新日期：1979-04-01 00:00:00

abstract：:Soft tissue tumours represent a heterogeneous group of mesenchymal lesions and their classification continues to evolve as a result of incorporating advances in cytogenetic and molecular techniques. In the last decade, traditional diagnostic approaches were supplemented with a significant number of reliable molecular ...

journal_title：Pathology

authors： Antonescu CR,Dal Cin P

更新日期：2014-02-01 00:00:00

abstract：:Bordetella pertussis, the aetiological agent of whooping cough is routinely diagnosed by polymerase chain reaction (PCR) directed at IS481, an insertion sequence target also found in Bordetella holmesii. Recent reports have suggested that B. holmesii infections can be misdiagnosed as pertussis, which can have a signif...

journal_title：Pathology

authors： Fong W,Timms V,Holmes N,Sintchenko V

更新日期：2018-04-01 00:00:00

abstract：:Lymphadenopathy associated with hemorrhage as a presenting feature of primary (AL) amyloidosis has not previously been described. We report two such cases one of whom had an acquired factor X and IX deficiency. The clinical presentations were characterized by sudden spontaneous enlargement of lymph nodes followed by p...

journal_title：Pathology

authors： Hanley JP,MacLean FR,Evans JL,Colls BM,Robinson BA,Patton WN,Heaton DC

更新日期：2000-02-01 00:00:00

abstract：AIMS:To correlate the immunostaining for INI1 protein and mutations in INI1 gene in possible rhabdoid tumours (RT) and atypical teratoid/rhabdoid tumours (AT/RT) seen at the Royal Children's Hospital in the last 10 years, and to study the clinicopathological features of those patients with negative nuclear staining. M...

journal_title：Pathology

authors： Wu X,Dagar V,Algar E,Muscat A,Bandopadhayay P,Ashley D,Wo Chow C

更新日期：2008-12-01 00:00:00

abstract：:The prevalence of complement-fixing (CF) antibody against the AG-4 early antigen of herpes simplex virus (HSV) type 2 (HSV-2) was determined in patients with culture confirmed HSV-2 genital herpes and control groups using a commercial HSV-2 early antigen (Simplex-2; Gene Link Australia Ltd). Eighty seven per cent of 3...

journal_title：Pathology

authors： Field PR,Ho DW,Cunningham AL

更新日期：1992-10-01 00:00:00

abstract：:The heparin dependent platelet aggregating factor in the serum from an individual with heparin induced thrombocytopenia exhibited reactivity with only 50% of an extensive panel of normal platelet rich plasmas, and this variability was independent of the platelet rich plasma platelet Factor 4 content. Individual sera o...

journal_title：Pathology

authors： Salem HH,van der Weyden MB

更新日期：1983-07-01 00:00:00

abstract：AIMS:To examine the impact of microwave (MW) tissue processing on turnaround times (TATs) in a routine diagnostic laboratory. METHODS:A retrospective review of TATs for tissue processing (specimen receipt to completion of H&E-stained section) and pathologists' report generation (receipt of stained section to validatio...

journal_title：Pathology

authors： Leong AS,Price D

更新日期：2004-08-01 00:00:00

abstract：:The case is reported of a woman aged 60 yrs who presented with systemic symptoms and who was found to have proteinuria of 3.5 g per day. A renal biopsy revealed numerous neoplastic cells filling many of the glomerular capillary lumina. Immunoperoxidase stains revealed that the phenotype of the malignant cells was LCA+...

journal_title：Pathology

authors： Axelsen RA,Laird PP,Horn M

更新日期：1991-07-01 00:00:00

abstract：:The alkaline phosphatase from neutrophils of pregnant women and normal males has been extracted, subjected to various inhibitory procedures and to electrophoresis. It is demonstrated that the iso-enzyme obtained from each group is indistinguishable from the skeletal iso-enzyme, in contrast to the serum iso-enzyme of p...

journal_title：Pathology

authors： Findlay AB,Johnston NG

更新日期：1977-01-01 00:00:00

abstract：:The estrogen receptor (ER) content of breast carcinoma is generally accepted as valuable in predicting clinical outcome and tumour response to hormonal manipulation. We applied a new immunocytochemical assay for estrogen receptors (Abbott ERICA Monoclonal) to 20 breast tumours, and examined the efficacy of 16 fixation...

journal_title：Pathology

authors： Raymond WA,Leong AS

更新日期：1988-10-01 00:00:00

abstract：:Ulex europaeus agglutinin-1 (UEA-1) binds specifically to alpha-L-fucose, the terminal sugar of blood group substances H2 and Ley the expression of which is confined mainly to the proximal colon. The aim of the study was to determine whether there is neo-expression of alpha-L-fucose in the normal appearing mucosa of t...

journal_title：Pathology

authors： Jass JR,Allison LJ,Stewart SM,Lane MR

更新日期：1993-04-01 00:00:00

abstract：:Recent controversies both in Australia and overseas have focused public attention on autopsy practice. It has become apparent that there is an increasing expectation amongst the public for more detailed information concerning autopsy procedures and, in particular, tissue retention. This article attempts to review the ...

journal_title：Pathology

authors： Lynch MJ

更新日期：2002-02-01 00:00:00

abstract：:Iron tablets are widely used in the community. Severe, sometimes lethal, damage to the gastrointestinal tract following overdose is well known, but there is less appreciation of the damage that can be caused by therapeutic dosage. In this histological study of three esophageal lesions and six gastric lesions (includin...

journal_title：Pathology

authors： Eckstein RP,Symons P

更新日期：1996-05-01 00:00:00

abstract：:Prenatal diagnoses of the genetic disorders alpha, beta thalassemia, HbS, Hb Lepore, hemophilia and cystic fibrosis were sought in 88 cases. Six unsuccessful attempts at diagnosis resulted from DNA polymorphisms which were only 50% informative (four cases) and prenatal diagnoses which had been undertaken before it was...

journal_title：Pathology

authors： Trent RJ,Volpato F,Wallace RC,Lindeman R,Yakas J

更新日期：1990-07-01 00:00:00

abstract：:Birth defects of the brain result from malformation and disruptions. They remain an important cause of childhood morbidity and mortality. Effective treatments are scarce and prevention strategies limited. As aetiological screening is costly and uncertain, genetic counselling remains empirical in most cases. A patholog...

journal_title：Pathology

authors： Encha-Razavi F,Gonzalès M,Laquerrière A,Martinovic J,Sinico M,Allias F,Bonnière M,Esculpavit C,Gerard M,Attié-Bitach T,Vekemans M

更新日期：2008-02-01 00:00:00

abstract：:In order to determine whether routine culturing for Clostridium difficile was warranted or whether culturing a selected group of patients was adequate, we conducted a prospective trial of culturing all stool specimens for C. difficile. A total of 408 specimens from 297 patients was studied. Two hundred and eighteen st...

journal_title：Pathology

authors： Bowman RA,Riley TV

更新日期：1984-07-01 00:00:00

abstract：:In various tumor types dentritic cell, infiltration and the presence of tumor-infiltrating lymphocytes have been associated with an improved clinical outcome. In the uterine cervix these immunocompetent cells have been associated with improved prognosis in high stage disease. The current study examines the significanc...

journal_title：Pathology

authors： Bethwaite PB,Holloway LJ,Thornton A,Delahunt B

更新日期：1996-11-01 00:00:00

abstract：:Forty four ventilated premature infants from three Neonatal Intensive Care Units around Melbourne were evaluated prospectively for evidence of Ureaplasma urealyticum and Chlamydia trachomatis infection in the respiratory tract. No C. trachomatis was found and this probably reflects the low prevalence of genital carria...

journal_title：Pathology

authors： Garland SM,Bowman ED

更新日期：1996-08-01 00:00:00

abstract：:The morphology of livers of Wistar rats treated with beta-carotene (BC), vitamin A (VA, retinol acetate) or corn oil (CO, controls) and submitted to the resistant hepatocyte model of carcinogenesis was studied. Preneoplastic lesions (PNL) were smaller and less numerous in the BC group. The latter group also presented ...

journal_title：Pathology

authors： Dagli ML,Guerra JL,Sinhorini IL,Wu TS,Rizzi MB,Penteado MV,Moreno FS

更新日期：1998-08-01 00:00:00

abstract：:Understanding human genetic variation and how it impacts on gene function is a major focus in genomic-based research. Translation of this knowledge into clinical care is exemplified by pharmacogenetics/pharmacogenomics. The identification of particular gene variants that might influence drug uptake, metabolism, distri...

journal_title：Pathology

authors： Trent RJ,Cheong PL,Chua EW,Kennedy MA

更新日期：2013-06-01 00:00:00

abstract：:Appropriate investigation of a patient with suspected von Willebrand's disease (VWD) involves a clinical assessment of the patient followed by laboratory testing. A variety of laboratory assays may be performed, not necessarily restricted to an assessment of von Willebrand factor (VWF). Due to the limitations of each ...

journal_title：Pathology

authors： Favaloro EJ,Koutts J

更新日期：1997-11-01 00:00:00

abstract：:The aim of the present study is to describe the histological and mutational characteristics of a series of both large and small bowel adenocarcinomas in patients with Crohn's disease from a tertiary referral centre of inflammatory bowel disease. Bowel adenocarcinoma was diagnosed in 11 (1.7%) of 660 consecutive patien...

journal_title：Pathology

authors： Malvi D,Vasuri F,Mattioli B,Gruppioni E,Fiorentino M,Gionchetti P,Grigioni WF,Poggioli G,D'Errico-Grigioni A

更新日期：2014-08-01 00:00:00

abstract：AIM:Lignocaine, a topical anaesthetic agent, is generally used in variable concentrations usually between 2% and 4% on the vocal cords prior to flexible bronchoscopy and bronchoalveolar lavage (BAL) procedures. The aim of this study was to investigate whether 2% or 1% lignocaine significantly inhibits the growth of org...

journal_title：Pathology

authors： Chandan SS,Faoagali J,Wainwright CE

更新日期：2005-08-01 00:00:00

abstract：:Ethanol in blood was assayed by 2 currently available procedures: a commercial kit enzymatic assay and a gas chromatographic procedure. Both methods were performed with commercially available materials and equipment. Results by the 2 procedures agreed well. For the 192 specimens studied, the correlation coefficient wa...

journal_title：Pathology

authors： Taylor GF,Turrill GH,Carter NG

更新日期：1984-04-01 00:00:00