Effect on organism recovery rate from BacT/Alert blood cultures with reduced incubation period.


:This retrospective study evaluated 15,377 sets of BacT/Alert blood cultures to determine incubation time for blood cultures. Ninety-six per cent (1476) of total isolates signalled positive within five days and 56 isolates turned positive in five to seven days. Of the 56 organisms recovered between five and seven days, 49 were considered contaminants and seven were considered clinically significant. On assessing the medical records of the patients with the seven clinically significant isolates, it was determined that the clinical outcome would not have changed if these isolates were missed. We conclude that a five day incubation protocol reduces the recovery of skin contaminants while not significantly decreasing the recovery of clinically significant organisms. The data suggest that the incubation time can be further reduced but this policy will depend on the individual institution and their patient population mix.






Mukerjee C,Heron LG,Varettas K




Has Abstract


1998-05-01 00:00:00












  • The liver sinusoidal cells. Their role in disorders of the liver, lipoprotein metabolism and atherogenesis.

    abstract::A review of the morphological and metabolic interactions between hepatocytes, the various sinusoidal cells and sinusoidal blood is presented. This field of investigation is rapidly expanding, with widespread implications in the regulation of physiological processes and diseases in the liver and other organs. Although ...


    pub_type: 杂志文章,评审


    authors: Fraser R,Day WA,Fernando NS

    更新日期:1986-01-01 00:00:00

  • Mitral and aortic valve abnormalities in a patient with fibrodysplasia ossificans progressiva.

    abstract::A 36-yr-old female with a 20-yr history of fibrodysplasia ossificans progressiva (FOP) died as the result of ruptured gastric ulcers. The patient had been treated with disodium ethane-l-hydroxy-1, 1-diphosphonate (EHDP). Post mortem there was thickening of the aortic valve cusps and mitral valve leaflets as well as sh...


    pub_type: 杂志文章


    authors: Jaworski RC,Gibson M

    更新日期:1983-07-01 00:00:00

  • Inverse relationships between the expression of MMP-7 and MMP-11 and predictors of poor prognosis of papillary thyroid carcinoma.

    abstract:AIMS:Matrix metalloproteinases (MMPs) have various functions that play roles in carcinoma development. In this study, we investigated the expression of two representative MMPs, MMP-7 and MMP-11, in papillary thyroid carcinomas. METHODS:We immunohistochemically investigated the expression of these MMPs in 196 cases of ...


    pub_type: 杂志文章


    authors: Ito Y,Yoshida H,Kakudo K,Nakamura Y,Kuma K,Miyauchi A

    更新日期:2006-10-01 00:00:00

  • Diffuse mesothelioma of the peritoneum: correlation between histological and clinical parameters and survival in 73 patients.

    abstract::There are few studies addressing survival of diffuse peritoneal mesotheliomas (DPM).In this study, survival data were obtained retrospectively from 73 patients treated with intended cytoreductive surgery for DPM, with a mean follow-up of 42 months. Mesotheliomas were classified as well differentiated papillary (WDPM, ...


    pub_type: 杂志文章


    authors: Liu S,Staats P,Lee M,Alexander HR,Burke AP

    更新日期:2014-12-01 00:00:00

  • Precursors and pathogenesis of ovarian carcinoma.

    abstract::The ultimate goal of defining cancer specific precursors is to facilitate early detection and intervention before the development of invasive malignancy. Unlike other malignancies involving the female genital tract such as cervical or endometrial carcinomas, precursor lesions of ovarian carcinomas have not been well c...


    pub_type: 杂志文章,评审


    authors: Lim D,Oliva E

    更新日期:2013-04-01 00:00:00

  • Eosinophilia and mast cell hyperplasia induced by parasite phospholipid.

    abstract::Phospholipid preparations from the nematode Ascaris suum or cysts of Echinococcus granulosus (hydatid cysts) induced an eosinophilia when injected into the peritoneal cavity of rats. Peritoneal eosinophilia persisted throughout 21 days of daily injections of Ascaris lipid and was accompanied by blood eosinophilia, mas...


    pub_type: 杂志文章


    authors: Archer GT,Robson JE,Thompson AR

    更新日期:1977-04-01 00:00:00

  • The autopsy: legal and ethical principles.

    abstract::Recent controversies both in Australia and overseas have focused public attention on autopsy practice. It has become apparent that there is an increasing expectation amongst the public for more detailed information concerning autopsy procedures and, in particular, tissue retention. This article attempts to review the ...


    pub_type: 杂志文章,评审


    authors: Lynch MJ

    更新日期:2002-02-01 00:00:00

  • Predilection of experimental arterial aneurysms for dietary-induced lipid deposition.

    abstract::In 14 stock rabbits experimental aneurysms (saccular, fusiform or berry) were produced on the common carotid artery or the aorta by microvascular surgery using a modification of the venous pouch technique. The animals were given a cholesterol-rich diet at varying times postoperatively to determine the susceptibility o...


    pub_type: 杂志文章


    authors: Stehbens WE

    更新日期:1981-10-01 00:00:00

  • Serpin B4 isoform overexpression is associated with aberrant epithelial proliferation and lung cancer in idiopathic pulmonary fibrosis.

    abstract:AIMS:The aim of the study was to evaluate the role of Serpin B3/B4 in advanced idiopathic pulmonary fibrosis (IPF) patients, mainly focusing on epithelial proliferation. METHODS:Lungs from 48 IPF patients (including cases with cancer or high-grade epithelial dysplasia) were studied and compared with other diffuse pare...


    pub_type: 杂志文章


    authors: Calabrese F,Lunardi F,Balestro E,Marulli G,Perissinotto E,Loy M,Nannini N,Valente M,Saetta M,Agostini C,Rea F

    更新日期:2012-04-01 00:00:00

  • Chromosome analysis of bone marrow samples from country patients.

    abstract::Co-operation by outside centres has made it possible to offer bone marrow chromosome analysis to patients living up to 1800 kilometres from the central cytogenetics laboratory. Diagnostic karyotypes have been obtained in 9 of 10 bone marrow specimens which were partially processed before being transported to the city ...


    pub_type: 杂志文章


    authors: Bell JA

    更新日期:1978-07-01 00:00:00

  • Sensitivity of respiratory bacteria to lignocaine.

    abstract:AIM:Lignocaine, a topical anaesthetic agent, is generally used in variable concentrations usually between 2% and 4% on the vocal cords prior to flexible bronchoscopy and bronchoalveolar lavage (BAL) procedures. The aim of this study was to investigate whether 2% or 1% lignocaine significantly inhibits the growth of org...


    pub_type: 杂志文章


    authors: Chandan SS,Faoagali J,Wainwright CE

    更新日期:2005-08-01 00:00:00

  • Histological comparison of partial hydatidiform mole and trisomy gestation specimens.

    abstract::The distinction between partial hydatidiform mole (PHM) and trisomy gestation is not always straightforward histologically and it is unclear which morphological features, alone or in combination, provide the greatest diagnostic accuracy. We performed a comparative review of 89 products of conception (POC) specimens in...


    pub_type: 杂志文章


    authors: Wilson Y,Bharat C,Crook ML,Kee AR,Peverall J,Ruba S,Stewart CJ

    更新日期:2016-10-01 00:00:00

  • The histological and ultrastructural features of the epiphyseal plate in Morquio type A syndrome (mucopolysaccharidosis type IVA).

    abstract::Tissue from the epiphyseal plate of a patient with Morquio type A syndrome (mucopolysaccharidosis type IVA) was studied by undecalcified histological and electron microscopical techniques. Cartilage cells in the plate were vacuolated to a variable degree. The orderly proliferating structure of the epiphyseal plate was...


    pub_type: 杂志文章


    authors: McClure J,Smith PS,Sorby-Adams G,Hopwood J

    更新日期:1986-04-01 00:00:00

  • Seven patients with respiratory infections due to Corynebacterium pseudodiphtheriticum.

    abstract::Seven cases of lower respiratory tract infection due to Corynebacterium pseudodiphtheriticum are described. Lower respiratory tract infections with C. pseudodiphtheriticum in immunocompetent patients are usually associated with pre-existing chronic pulmonary disease, and are sometimes associated with endotracheal intu...


    pub_type: 杂志文章


    authors: Freeman JD,Smith HJ,Haines HG,Hellyar AG

    更新日期:1994-07-01 00:00:00

  • Erythroblastosis fetalis--the discovery and partial elimination of rhesus incompatibility--the origins of exchange transfusion in Australia.

    abstract::The first 2 exchange transfusions in Australia for Rhesus-induced erythroblastosis (hemolytic disease of the newborn) were conducted in the 9 mth period from December 1945 to August 1946. These pioneering endeavours in medical research were undertaken by 3 transfusionists who were, or had been, directors of the Red Cr...


    pub_type: 历史文章,杂志文章


    authors: Pearn JH

    更新日期:1994-04-01 00:00:00

  • The preparation of glomeruli from renal biopsy specimens for scanning electron microscopy.

    abstract::A method for the preparation of human renal biopsy specimens for scanning electron microscopy (SEM) is described. This involves glomerular isolation by fine needle dissection and the simultaneous processing of 10 or more specimens in a specially designed tissue cassette. The method is simple and reliable with minimal ...


    pub_type: 杂志文章


    authors: Ng W,So KF,So PC,Ngai HK

    更新日期:1982-07-01 00:00:00

  • Sensitive and high sensitivity next generation cardiac troponin assays: more than just a name.

    abstract::In the 20 years that cardiac troponin testing has been available in clinical laboratories, the biomarker has revolutionised testing of patients with acute coronary syndromes. Cardiac troponin I and T testing has become the cornerstone for diagnosis of myocardial infarction and is useful for risk assessment and managem...


    pub_type: 杂志文章,评审


    authors: Christenson RH,Phillips D

    更新日期:2011-04-01 00:00:00

  • Immunophenotypic analysis of non-Hodgkin's lymphomas in Chinese. A study of 75 cases in Hong Kong.

    abstract::The cell surface markers of 75 cases of non-Hodgkin's lymphoma were studied on cryostat sections using a panel of monoclonal antibodies. Forty-nine cases (65.3%) were found to express a B-cell phenotype, 23 cases (30.7%) a T-cell phenotype, 1 case (1.3%) a histiocytic phenotype and 2 cases (2.7%) no demonstrable surfa...


    pub_type: 杂志文章


    authors: Ng CS,Chan JK,Lo ST,Poon YF

    更新日期:1986-10-01 00:00:00

  • High reproducibility is attainable in assessing histoprognostic parameters of pT1 colorectal cancer using routine histopathology slides and immunohistochemistry analyses.

    abstract::Assessment of the risk of lymph node invasion and tumour recurrence is critical to determine whether additional surgery is required in patients with endoscopically-removed pT1 colorectal cancer (CRC). A reproducible assessment of this risk of recurrence based on histopathological parameters is crucial for relevant the...


    pub_type: 杂志文章


    authors: Barel F,Auffret A,Cariou M,Kermarrec T,Samaison L,Bourhis A,Badic B,Jézéquel J,Cholet F,Bail JP,Marcorelles P,Nousbaum JB,Robaszkiewicz M,Doucet L,Uguen A

    更新日期:2019-01-01 00:00:00

  • Prevalence and biological behaviour of variants of papillary thyroid carcinoma: experience at a single institute.

    abstract:AIMS:There are many variants of papillary carcinoma, and some of these variants have been reported to show biological behaviours differing from that of conventional papillary carcinoma. In this study, we present our experience regarding the prevalence and prognoses of these variants of papillary carcinoma. METHODS:H&E...


    pub_type: 杂志文章


    authors: Ito Y,Hirokawa M,Uruno T,Kihara M,Higashiyama T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Miyauchi A

    更新日期:2008-10-01 00:00:00

  • Discordant neutrophil alkaline phosphatase activity and cytogenetic response in chronic myeloid leukemia treated with alpha-interferon.

    abstract::Decreased neutrophil alkaline phosphatase (NAP) synthesis is a classical feature of Philadelphia (Ph) positive chronic phase chronic myeloid leukemia (CML). Whether this aberration is an integral leukemic property of the cell or results from mediation by other factors is unclear. During alpha-interferon (alpha-IFN) ba...


    pub_type: 杂志文章


    authors: Taylor DL,Kerwick AM,Elliott SL,Rodwell RL,Wright SJ,Marlton PV,Veleba AR,Taylor KM

    更新日期:1993-10-01 00:00:00

  • Not only 'Flinders Island' spotted fever.

    abstract:AIM:To demonstrate that Flinders Island spotted fever (FISF), a spotted fever group rickettsial infection caused by Rickettsia honei, is found not only on Flinders Island (Bass Strait), Tasmania, but elsewhere in south-east Australia. METHODS:Cases of FISF were identified by rickettsial serology, culture and the detec...


    pub_type: 杂志文章


    authors: Unsworth NB,Stenos J,McGregor AR,Dyer JR,Graves SR

    更新日期:2005-06-01 00:00:00

  • An improved screening method for 3-methoxy-4-hydroxy mandelic acid excretion in urine.

    abstract::A screening method is described for urinary 3-methoxy-4-hydroxy mandelic acid using an initial ion exchange procedure, vanillin formation and extraction into toluene. The technique, is simple, rapid and specific, with a reference value up to 35 mumol (7.0 mg)/day established on 92 normal human subjects. Over 200 patie...


    pub_type: 杂志文章


    authors: Rumble BA,Dick M

    更新日期:1978-01-01 00:00:00

  • A comparison of structural features of the walls of coronary arteries from 10 different species.

    abstract::The intimal thickness of the coronary arteries of humans less than 20 years of age was compared with that 9 other species. It was found that humans were unique amongst the species studied in showing substantial intimal thickening at an early age. The intimal thickening was associated with defects of the internal elast...


    pub_type: 杂志文章


    authors: Sims FH

    更新日期:1989-04-01 00:00:00

  • The value of endomyocardial biopsy in diagnosis and guiding therapy.

    abstract::Endomyocardial biopsy (EMB) is a highly-specialised procedure that is associated with some controversy as to its diagnostic role due to its inconsistency in diagnosing a wide variety of cardiac diseases. Given the advances and sophistication in echocardiography and cardiac magnetic resonance imaging (MRI), the vast ma...


    pub_type: 杂志文章


    authors: Khan T,Selvakumar D,Trivedi S,Rao K,Harapoz M,Thiagalingam A,Denniss AR,Varikatt W

    更新日期:2017-12-01 00:00:00

  • Isolated dissection of the coronary artery: a postmortem study of seven cases.

    abstract::We present the clinical and postmortem findings in seven adults (four females and three males), who died with dissection of the coronary arteries. The median age was 56 years. Five of the coronary artery dissections (CADs) were spontaneous and two followed trauma: one a motor vehicle accident, the other occurred durin...


    pub_type: 杂志文章


    authors: Mulvany NJ,Ranson DL,Pilbeam MC

    更新日期:2001-08-01 00:00:00

  • Overexpression of HOMER2 predicts better outcome in low-grade endometrioid endometrial adenocarcinoma.

    abstract::We have previously shown that HOMER2 (Homer scaffolding protein 2), a protein coding gene, was highly expressed in low grade (LG) endometrioid adenocarcinoma (EAC) of the uterus. The role of HOMER2 in endometrial cancer (EC) is widely unknown; therefore, the aim of this study was to determine the expression and the pr...


    pub_type: 杂志文章


    authors: Mhawech-Fauceglia P,Walia S,Yessaian A,Machida H,Matsuo K,Lawrenson K

    更新日期:2018-08-01 00:00:00

  • The elaboration of a critical framework for understanding cancer: the cancer stem cell hypothesis.

    abstract::The cancer stem cell hypothesis suggests that malignant tumours may arise from a limited number of specialised cells possessing the key 'stem' properties of self-renewal and the ability to produce differentiated progeny. Such cells purportedly constitute a small fraction of most tumours but have greater potential to p...


    pub_type: 杂志文章,评审


    authors: Hemmings C

    更新日期:2010-02-01 00:00:00

  • Advances in laboratory testing for HIV.

    abstract::In 2004, the diagnosis of established human immunodeficiency virus (HIV) infection can be made with close to 100% assurity. The extraordinarily engineered performances of HIV-screening assays are unprecedented. The well-established confirmatory tests performed by well-versed laboratories using criteria that are well u...


    pub_type: 杂志文章,评审


    authors: Dax EM,Arnott A

    更新日期:2004-12-01 00:00:00

  • Development of paediatric biochemistry centile charts as a complement to laboratory reference intervals.

    abstract::Age-specific paediatric reference intervals are used in interpretation of laboratory results. However, interpretation may be problematic when a child just crosses an age bracket and the difference between the original and the subsequent age-specific reference interval is large. Moreover, details about the physiologica...


    pub_type: 杂志文章


    authors: Loh TP,Antoniou G,Baghurst P,Metz MP

    更新日期:2014-06-01 00:00:00