Recurrent pyogenic cholangitis: a necropsy study.

Abstract:

:Forty-six necropsy cases of recurrent pyogenic cholangitis (RPC) among Chinese in Hong Kong were reviewed. Intrahepatic biliary pigment stones or bile sludge were present in all cases and liver abscesses were common (80%). Histologically the early lesion was marked by acute inflammation in portal tracts with frequent pylethrombophlebitis and the advanced chronic lesion by periductal fibrosis. Most patients died from chronic persistent hepatic suppuration or disseminated infection. The pathogenesis is not fully understood; the present study favours the view that a protein-deficient diet initiates intrahepatic stone or sludge formation with biliary obstruction; subsequent bacterial infection probably originates from the portal system.

journal_name

Pathology

journal_title

Pathology

authors

Chou ST,Chan CW

doi

10.3109/00313028009077105

subject

Has Abstract

pub_date

1980-07-01 00:00:00

pages

415-28

issue

3

eissn

0031-3025

issn

1465-3931

journal_volume

12

pub_type

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