LAMP1 expression is associated with malignant behaviours and predicts unfavourable prognosis in laryngeal squamous cell carcinoma.

abstract：AIM:It is routine practice to prolong the incubation period of blood cultures from patients with suspected subacute bacterial endocarditis (SBE) or fungal infection. The protocol in this laboratory required 28 days incubation with weekly subcultures. Following the introduction of automated continuously monitored blood ...

journal_title：Pathology

authors： Varettas K,Taylor PC,Mukerjee C

更新日期：2002-04-01 00:00:00

abstract：:Five cases of intraductal papillary-mucinous neoplasm (IPMN) of the pancreas are here described. This group of tumors represents a distinct clinicopathological entity with characteristic endoscopic, radiological, gross and microscopic appearances. Our five cases all showed marked dilatation of the main pancreatic duct...

journal_title：Pathology

authors： Kench JG,Eckstein RP,Smith RC

更新日期：1997-02-01 00:00:00

abstract：:Soft tissue tumours are relatively rare, but are diagnostically challenging as they comprise a large spectrum of diagnostic entities. Substantial advances have been made in recent years in identifying the underlying recurrent chromosomal and genomic alterations in a significant subset of soft tissue tumours, and this ...

journal_title：Pathology

authors： Schaefer IM,Fletcher CDM

更新日期：2018-01-01 00:00:00

abstract：AIM:Clostridium difficile is the major pathogen associated with nosocomial diarrhoea. We evaluated the performances of a commercially available toxin A enzyme immunoassay (EIA; Clearview C. difficile Toxin A Test), culture and tissue culture cytotoxin assay in the diagnosis of C. difficile-associated diarrhoea. METHOD...

journal_title：Pathology

authors： Anderson TL,McGregor A

更新日期：2003-06-01 00:00:00

abstract：:Cytological examination of the pleural effusion fluid obtained from a 66-yr-old Chinese lady showed numerous intra- and extracytoplasmic colourless refractile non-birefringent crystals. X-ray analysis of the crystals identified barium salts. On further inquiry, it was learnt that the fluid obtained had been placed in ...

journal_title：Pathology

authors： Chan AC,Collins RJ,Cheung TK

更新日期：1993-10-01 00:00:00

abstract：:Statistical methods have been used to determine an optimal approach to the definition of the reference range for CD4 ("helper") and CD8 ("suppressor/cytotoxic") T cell numbers and the CD4/CD8 ratio in the peripheral blood. A graphical presentation of the absolute values for CD4 and CD8 for 85 healthy blood donors show...

journal_title：Pathology

authors： Zachar V,Mikulecky M,Mayer V,Mackay I,Frazer I

更新日期：1988-10-01 00:00:00

abstract：AIMS:We assessed the expression of ALDH1 and EZH2, cancer stem cell (CSC) related markers, in triple negative and basal-like breast cancers, investigating their association with clinicopathological features and outcome. METHODS:Clinicopathological data were obtained from 140 cases of triple negative breast cancer. A t...

journal_title：Pathology

authors： De Brot M,Rocha RM,Soares FA,Gobbi H

更新日期：2012-06-01 00:00:00

abstract：:We present the clinical and postmortem findings in seven adults (four females and three males), who died with dissection of the coronary arteries. The median age was 56 years. Five of the coronary artery dissections (CADs) were spontaneous and two followed trauma: one a motor vehicle accident, the other occurred durin...

journal_title：Pathology

authors： Mulvany NJ,Ranson DL,Pilbeam MC

更新日期：2001-08-01 00:00:00

abstract：:Weanling rats were given a low Ca (0.003%)/high P (0.64%) diet with and without vitamin D for periods up to 6 weeks. An ultrastructural examination of selected areas of the proximal tibial metaphysis was carried out to study osteoclasts and their relation to calcified and uncalcified bone tissue. Osteoclasts were seen...

journal_title：Pathology

authors： Feik SA,Storey E

更新日期：1979-10-01 00:00:00

abstract：:Distinction between melanocytic naevi and melanoma occasionally poses a diagnostic challenge in ambiguous cases showing overlapping histological features. Melanomas are characterised by the presence of multiple genomic copy number variants (CNVs), while this is not a feature of naevi. We assessed the feasibility and u...

journal_title：Pathology

authors： Mesbah Ardakani N,Thomas C,Robinson C,Mina K,Harvey NT,Amanuel B,Wood BA

更新日期：2017-04-01 00:00:00

abstract：:Soft tissue tumours represent a heterogeneous group of mesenchymal lesions and their classification continues to evolve as a result of incorporating advances in cytogenetic and molecular techniques. In the last decade, traditional diagnostic approaches were supplemented with a significant number of reliable molecular ...

journal_title：Pathology

authors： Antonescu CR,Dal Cin P

更新日期：2014-02-01 00:00:00

abstract：:Antibodies that bind phospholipid (anti-phospholipid antibodies [APA]) are a focus of major interest to both clinical and laboratory personnel across a variety of disciplines because of the assortment of disorders with which they are reportedly associated. A solid phase assay using cardiolipin as the test phospholipid...

journal_title：Pathology

authors： Favaloro EJ,Silvestrini R,Mohammed A

更新日期：1999-05-01 00:00:00

abstract：AIMS:This study was undertaken to investigate the genetic factors underlying the development of multifocality and phenotypic diversity in multifocal papillary thyroid carcinoma (mPTC). METHODS:Loss of heterozygosity (LOH) and BRAF(V600E) mutation status were analysed in a total of 55 individual tumour foci from 18 cas...

journal_title：Pathology

authors： Jovanovic L,Delahunt B,McIver B,Eberhardt NL,Bhattacharya A,Lea R,Grebe SK

更新日期：2010-01-01 00:00:00

abstract：AIMS:Predicting the clinical behaviour of gastrointestinal stromal tumours (GISTs) is difficult and criteria delineating benign from malignant cases are not firmly established. The aims of this study were to define the clinicopathological and molecular features of 66 GISTs, and to determine whether any specific paramet...

journal_title：Pathology

authors： Koay MH,Goh YW,Iacopetta B,Grieu F,Segal A,Sterrett GF,Platten M,Spagnolo DV

更新日期：2005-02-01 00:00:00

abstract：:A rare case of extraskeletal osteosarcoma of the scalp in a 56-year-old woman is described. At presentation she was found to have an 8-cm diameter, tender, firm, exophytic scalp tumor. MRI scan confirmed absence of underlying skeletal origin and showed extension along the subcutaneous plane. The tumor was excised and ...

journal_title：Pathology

authors： Pillay P,Simango S,Govender D

更新日期：2000-05-01 00:00:00

abstract：AIMS:The increasing importance of cardiac disease has generated an interest in improved screening strategies regarding preclinical cardiac abnormalities and employing measurement of circulating biomarkers. This review focuses on the utility of the B-type natriuretic peptides (NP) and the cardiac troponins (cTns) for th...

journal_title：Pathology

authors： Eggers KM,Venge P

更新日期：2012-02-01 00:00:00

abstract：:Phospholipid preparations from the nematode Ascaris suum or cysts of Echinococcus granulosus (hydatid cysts) induced an eosinophilia when injected into the peritoneal cavity of rats. Peritoneal eosinophilia persisted throughout 21 days of daily injections of Ascaris lipid and was accompanied by blood eosinophilia, mas...

journal_title：Pathology

authors： Archer GT,Robson JE,Thompson AR

更新日期：1977-04-01 00:00:00

abstract：:This report describes the diagnostic problem caused by an atypical immunoglobulin-bound creatine kinase isoenzyme in a patient who had a myocardial infarction. In the presence of this atypical isoenzyme, creatine kinase isoenzyme electrophoresis was of no help in determining whether myocardial infarction had occurred....

journal_title：Pathology

authors： Campbell BG,Jones BW,Burnet J

更新日期：1990-01-01 00:00:00

abstract：:We describe a case of ductal carcinoma in situ (DCIS) occurring in a fibroadenoma diagnosed by fine needle aspiration (FNA) cytology. The cytological features comprised a small population of pleomorphic cells admixed with a dominant population of bland epithelial cells showing features consistent with those of a fibro...

journal_title：Pathology

authors： Psarianos T,Kench JG,Ung OA,Bilous AM

更新日期：1998-11-01 00:00:00

abstract：:Lymph node metastasis (LNM) is an important factor for predicting prognosis and selecting appropriate treatment in early gastric cancers (EGCs). We investigated the histopathological and microenvironmental predictors of LNM in EGCs. We retrieved 43 cases of EGC without LNM and 59 cases with LNM. Clinicopathological va...

journal_title：Pathology

authors： Kim JY,Kim CH,Lee Y,Lee JH,Chae YS

更新日期：2017-10-01 00:00:00

abstract：:A retrospective review of coronial records was performed for 179 adult decedents who came to coronial autopsy in 1990 and who had been living in the Top End of the Northern Territory at the time of death. The directly standardized rate of autopsy-examined sudden death was 7.4 times higher for Aboriginal people than fo...

journal_title：Pathology

authors： Weeramanthri TS,Powers JR,Collier JW

更新日期：1996-01-01 00:00:00

abstract：AIMS:INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ). METHODS:INI1 was determined by immunohistochemistry and MGMT by methylation-specific PCR. RESULTS...

journal_title：Pathology

authors： Zunarelli E,Bigiani N,Sartori G,Migaldi M,Sgambato A,Maiorana A

更新日期：2011-01-01 00:00:00

abstract：:An elderly woman had a cerebral gliosarcoma with a single pulmonary metastasis, together with a separate pulmonary adenoid-cystic carcinoma. Spontaneous extraneural metastases of primary intracranial neoplasms are exceedingly unusual; so far, only 8 proven cases are recorded in the English language medical literature....

journal_title：Pathology

authors： Ojeda VJ,Sterrett GF

更新日期：1984-04-01 00:00:00

abstract：:The main controversy about nerve sheath tumors (NSTs) has been their histogenesis. A Schwann cell origin has been proposed by many investigators for both schwannomas and neurofibromas. However Erlandson and Woodruff observed that while schwannomas appeared to be composed predominantly of Schwann cells, neurofibromas c...

journal_title：Pathology

authors： Kharbanda K,Dinda AK,Sarkar C,Karak AK,Mathur M,Roy S

更新日期：1994-01-01 00:00:00

abstract：:The monitoring of infliximab drug levels aids in the management of several autoimmune diseases, notably inflammatory bowel disease. Several commercial kits are now available and approved by the Therapeutic Goods Administration (TGA) for the measurement of infliximab levels, but there have been limited verification or ...

journal_title：Pathology

authors： Lee MW,Connor S,Ng W,Toong CM

更新日期：2016-10-01 00:00:00

abstract：:Epigenetic regulation is emerging as a critical mechanism for pancreatic ductal adenocarcinoma (PDA) development. Histone methylation is an important regulatory mechanism, altering chromatin structure and promoter accessibility and causing aberrant gene expression. NSD1 and SETD2 genes encoding two histone H3K36 methy...

journal_title：Pathology

authors： Ettel M,Zhao L,Schechter S,Shi J

更新日期：2019-06-01 00:00:00

abstract：:Mesenchymal stromal cells (MSCs) are a non-homogeneous population of plastic-adherent cells which were initially isolated from post-natal bone marrow. They have the capacity to differentiate to multiple mesodermal lineages including bone, cartilage and adipose tissue. In stringent culture conditions, MSCs can also be ...

journal_title：Pathology

authors： Larsen S,Lewis ID

更新日期：2011-10-01 00:00:00

abstract：:We report a patient with unusual venous and arterial thromboses in association with the common thermolabile methyltetrahydrofolate (MTHFR) variant. The patient responded directly to folate supplementation. To our knowledge, this is the first report describing hyperhomocysteinemia in association with this type of throm...

journal_title：Pathology

authors： Hall TN,Ramakrishnan LL,Leahy MF

更新日期：1999-02-01 00:00:00

abstract：:In situ stages of malignancy have been characterised in various neoplasms. Mesothelioma in situ (MIS) has been a controversial diagnosis, lacking clear diagnostic criteria and understanding as to whether it is truly a premalignant lesion in the progression of malignant mesothelioma (MM). Originally understood as a con...

journal_title：Pathology

authors： Pulford E,Henderson DW,Klebe S

更新日期：2020-10-01 00:00:00

abstract：:A 59 yr old male presented with abdominal pain and jaundice. CT scan showed a tumor in the pancreas with secondaries in the liver, peri-pancreatic lymph nodes, vertebral bone marrow and subcutaneous tissue of the neck together with a cervical lymph node. The patient died after 2 wks and autopsy revealed complete repla...

journal_title：Pathology

authors： Chetty R,Clark SP,Pitson GA

更新日期：1993-07-01 00:00:00