Lobular in situ neoplasia and columnar cell lesions: diagnosis in breast core biopsies and implications for management.

abstract：:There are few studies addressing survival of diffuse peritoneal mesotheliomas (DPM).In this study, survival data were obtained retrospectively from 73 patients treated with intended cytoreductive surgery for DPM, with a mean follow-up of 42 months. Mesotheliomas were classified as well differentiated papillary (WDPM, ...

journal_title：Pathology

authors： Liu S,Staats P,Lee M,Alexander HR,Burke AP

更新日期：2014-12-01 00:00:00

abstract：:A 36-yr-old female with a 20-yr history of fibrodysplasia ossificans progressiva (FOP) died as the result of ruptured gastric ulcers. The patient had been treated with disodium ethane-l-hydroxy-1, 1-diphosphonate (EHDP). Post mortem there was thickening of the aortic valve cusps and mitral valve leaflets as well as sh...

journal_title：Pathology

authors： Jaworski RC,Gibson M

更新日期：1983-07-01 00:00:00

abstract：:A rapid technique suitable for routine laboratory use for determining the percentage of large platelets in the peripheral blood is described. In 50 haematologically normal subjects, megathrombocytes (platelets with a volume of 16-33 fl) constituted 3.0-16.6% (mean +/- 2 SD) of the platelet count. Of the 10 patients ex...

journal_title：Pathology

authors： Hunt FA

更新日期：1976-01-01 00:00:00

abstract：:Assessment of the risk of lymph node invasion and tumour recurrence is critical to determine whether additional surgery is required in patients with endoscopically-removed pT1 colorectal cancer (CRC). A reproducible assessment of this risk of recurrence based on histopathological parameters is crucial for relevant the...

journal_title：Pathology

authors： Barel F,Auffret A,Cariou M,Kermarrec T,Samaison L,Bourhis A,Badic B,Jézéquel J,Cholet F,Bail JP,Marcorelles P,Nousbaum JB,Robaszkiewicz M,Doucet L,Uguen A

更新日期：2019-01-01 00:00:00

abstract：:Epigenetic regulation is emerging as a critical mechanism for pancreatic ductal adenocarcinoma (PDA) development. Histone methylation is an important regulatory mechanism, altering chromatin structure and promoter accessibility and causing aberrant gene expression. NSD1 and SETD2 genes encoding two histone H3K36 methy...

journal_title：Pathology

authors： Ettel M,Zhao L,Schechter S,Shi J

更新日期：2019-06-01 00:00:00

abstract：:A review of the morphological and metabolic interactions between hepatocytes, the various sinusoidal cells and sinusoidal blood is presented. This field of investigation is rapidly expanding, with widespread implications in the regulation of physiological processes and diseases in the liver and other organs. Although ...

journal_title：Pathology

authors： Fraser R,Day WA,Fernando NS

更新日期：1986-01-01 00:00:00

abstract：:The careers and contributions of some of those who have played a major role in the development of knowledge concerning gynaecological pathology are summarised. The emphasis is on workers of prior times beginning with those of the German-speaking school: Carl Ruge, Felix Marchand, Hermann Pfannenstiel, Oskar Frankl, Wa...

journal_title：Pathology

authors： Young RH

更新日期：2007-02-01 00:00:00

abstract：:A case is described of a mediastinal soft tissue sarcoma, in a 76-year-old man, characterized microscopically by the intimate combined features of liposarcoma and leiomyosarcoma. The lipomatous component consisted of well differentiated liposarcoma with myxoid areas. The smooth muscle component was characterized by fa...

journal_title：Pathology

authors： Gómez-Román JJ,Val-Bernal JF

更新日期：1997-11-01 00:00:00

abstract：:We aimed to evaluate the diagnostic utility of the novel immunohistochemical marker TROP-2 on thyroid specimens (226 tumours and 207 controls). Whole slide immunohistochemistry was performed and scored by automated digital image analysis. Non-neoplastic thyroid, follicular adenomas, follicular carcinomas, and medullar...

journal_title：Pathology

authors： Bychkov A,Sampatanukul P,Shuangshoti S,Keelawat S

更新日期：2016-08-01 00:00:00

abstract：:Since its first description in the early part of the twentieth century, struma ovarii has elicited considerable interest because of its many unique features; however, at present a number of aspects remain enigmatic. Although the typical presentation is that of a pelvic mass, unusual clinical manifestations such as hyp...

journal_title：Pathology

authors： Roth LM,Talerman A

更新日期：2007-02-01 00:00:00

abstract：AIMS:Recent study indicates that the binding of caveolin-1 (CAV1), the essential constituent of caveolae, to endothelial nitric oxide synthase (eNOS) prevents nitric oxide (NO) production in cirrhotic human liver. However, their interplay in hepatocellular carcinoma (HCC) remains undetermined. METHODS:Paraffin-embedde...

journal_title：Pathology

authors： Yang SF,Yang JY,Huang CH,Wang SN,Lu CP,Tsai CJ,Chai CY,Yeh YT

更新日期：2010-01-01 00:00:00

abstract：:A fatal case of multiple sulfatase deficiency in a 10-year-old girl is reported. In this rare disease, which is inherited as an autosomal recessive, features of metachromatic leukodystrophy and of mucopolysaccharidoses occur together. The white matter suffers progressive destruction with sulfatides accumulating in mac...

journal_title：Pathology

authors： Kepes JJ,Berry A 3rd,Zacharias DL

更新日期：1988-07-01 00:00:00

abstract：:The case is reported of a woman aged 60 yrs who presented with systemic symptoms and who was found to have proteinuria of 3.5 g per day. A renal biopsy revealed numerous neoplastic cells filling many of the glomerular capillary lumina. Immunoperoxidase stains revealed that the phenotype of the malignant cells was LCA+...

journal_title：Pathology

authors： Axelsen RA,Laird PP,Horn M

更新日期：1991-07-01 00:00:00

abstract：AIMS:It is currently accepted that primary ovarian tumours rarely, if ever, give rise to mucinous ascites/pseudomyxoma peritonei (PMP) which most commonly results from the intra-abdominal spread of an appendiceal mucinous neoplasm. However, primary ovarian mucinous tumours of appendiceal type arising within mature cyst...

journal_title：Pathology

authors： Stewart CJ,Tsukamoto T,Cooke B,Leung YC,Hammond IG

更新日期：2006-12-01 00:00:00

abstract：:In the peritoneal cavity of the adult rat mast cells at the four stages of progressive maturation (and corresponding increase of sulphation of granules) are best demonstrated in free peritoneal fluid. Of the 0.1-0.2x10(6) cells in the free fluid, 26% are at stage 1 of maturation (all granules are stained by Alcian blu...

journal_title：Pathology

authors： Yong LC,Watkins S,Wilhelm DL

更新日期：1975-10-01 00:00:00

abstract：AIMS:To demonstrate the correlation between morphological and proliferation parameters with the biological behaviour of adrenocortical tumours (ACTs) in different age groups. METHODS:Seventy-six cases of ACT were evaluated comparing tumours of children (< or =15 years, n=24) and adults (>15 years, n=52) regarding morp...

journal_title：Pathology

authors： Sredni ST,Alves VA,Latorre Mdo R,Zerbini MC

更新日期：2003-04-01 00:00:00

abstract：:A 14 yr old girl presented with a large cystic mass in the transverse mesocolon which was completely excised. Cystic lymphangioma was diagnosed, based on the specific histologic, immunoperoxidase and ultrastructural findings. ...

journal_title：Pathology

authors： Yuen ST,Ng IO,Ho J,Ma L

更新日期：1992-07-01 00:00:00

abstract：:The use of purified intrinsic factor in vitamin B12 radioassays has greatly reduced the misdiagnosis of pernicious anaemia in recent years, but anomalies still occur. Observations made on current vitamin B12 radioassays suggest that many methods fail to convert all serum cobalamins to cyanocobalamin and thus are not t...

journal_title：Pathology

authors： Brown RD,Robin H,Kronenberg H

更新日期：1982-01-01 00:00:00

abstract：:The present conventional methods for determination of Hemoglobin (Hb) concentration in whole blood depend on the direct colorimetric measurement of chemically modified Hb following its release from red cells by lysis. This paper examines an alternative, indirect method which does not require initial red cell lysis, co...

journal_title：Pathology

authors： Kalache GR,Sartor MM,Hughes WG

更新日期：1991-04-01 00:00:00

abstract：:Granulomatous (lobular) mastitis is a rare inflammatory breast disease affecting parous reproductive-aged women. Once considered idiopathic, there is growing evidence of an association with corynebacteria infection, especially in the setting of a distinct histological pattern termed cystic neutrophilic granulomatous m...

journal_title：Pathology

authors： Johnstone KJ,Robson J,Cherian SG,Wan Sai Cheong J,Kerr K,Bligh JF

更新日期：2017-06-01 00:00:00

abstract：:Prostatic stromal proliferations account for the majority of benign tumour-like lesions in the prostate. The most common is nodular hyperplasia, seen in a majority of elderly men. Diagnostic difficulty is encountered with some variants, including stromal hyperplasia with atypia, characterised by degenerative changes o...

journal_title：Pathology

authors： Bostwick DG,Egevad L

更新日期：2021-01-01 00:00:00

abstract：AIMS:The increasing importance of cardiac disease has generated an interest in improved screening strategies regarding preclinical cardiac abnormalities and employing measurement of circulating biomarkers. This review focuses on the utility of the B-type natriuretic peptides (NP) and the cardiac troponins (cTns) for th...

journal_title：Pathology

authors： Eggers KM,Venge P

更新日期：2012-02-01 00:00:00

abstract：:The estimation of plasma alanine aminotransferase (ALT) has been proposed as a surrogate test to identify potential non-A, non-B hepatitis carriers in blood donor populations. This report describes an ALT screening procedure which uses wells of microtitration trays as reactant vessels. The method utilizes a rate readi...

journal_title：Pathology

authors： Hyland CA,Douglas R,Mazzocchi R,Young IF

更新日期：1988-07-01 00:00:00

abstract：:Phospholipid preparations from the nematode Ascaris suum or cysts of Echinococcus granulosus (hydatid cysts) induced an eosinophilia when injected into the peritoneal cavity of rats. Peritoneal eosinophilia persisted throughout 21 days of daily injections of Ascaris lipid and was accompanied by blood eosinophilia, mas...

journal_title：Pathology

authors： Archer GT,Robson JE,Thompson AR

更新日期：1977-04-01 00:00:00

abstract：:Chromosome identification techniques have shown the non-random nature of cytogenetic changes in leukemia. In addition, they have identified structural chromosome abnormalities occurring in specific types of acute leukemia as classified by the FAB criteria. Such cytogenetic sub groups are associated with differing prog...

journal_title：Pathology

authors： Garson OM

更新日期：1982-07-01 00:00:00

abstract：:Ebolaviruses, and the other viral causes of haemorrhagic fevers (VHF) have always posed special problems for diagnostic laboratories. These arise from the rarity of human infections, minimal documented experience with test delivery and interpretation, the paucity of established commercial or in-house assays, the lack ...

journal_title：Pathology

authors： Smith DW,Rawlinson WD,Kok J,Dwyer DE,Catton M

更新日期：2015-08-01 00:00:00

abstract：:The results of semi-solid cultures of fresh biopsy material from 86 primary human melanomas are reported. Detailed histological assessments by Professor McGovern were available for 80 of the 86 melanomas, and these were compared with the growth characteristics of each specimen. Significant correlations were found betw...

journal_title：Pathology

authors： Vincent PC,Joyce RM,Croaker G,Young GA,Milton GW,McCarthy WH

更新日期：1985-04-01 00:00:00

abstract：:An analysis of prognostic factors in 4000 patients with cutaneous malignant melanoma at the Sydney Melanoma Unit and the University of Alabama in Birmingham has demonstrated that the histological features of the primary melanoma become less predictive of survival the more advanced the disease becomes. Thus, whilst 4 f...

journal_title：Pathology

authors： Shaw HM,Balch CM,Soong SJ,Milton GW,McCarthy WH

更新日期：1985-04-01 00:00:00

abstract：:Cervical biopsies obtained by colposcopic direction from 358 women were histologically examined for squamous dysplasia (cervical intra-epithelial neoplasia; CIN) and human papillomavirus (HPV) infection. Of the 358 biopsies, 136 were stained by an immunoperoxidase method using an antiserum against genus-specific (comm...

journal_title：Pathology

authors： Sterrett GF,Alessandri LM,Pixley E,Kulski JK

更新日期：1987-01-01 00:00:00

abstract：:All neoplasms of the ovary encountered in a 25-year study period at the King George V Memorial Hospital were classified according to the World Health Organisation Histological Classification of Ovarian Tumours. Of these, one thousand fell into the category designated as 'common epithelial tumours'. In this report a de...

journal_title：Pathology

authors： Russell P

更新日期：1979-04-01 00:00:00