Prognostic histopathological factors in malignant melanoma.

abstract：:The coexistence of a pancreatic papillary cystic tumor with hairy cell leukemia is reported. To the best of our knowledge this association has never been published. A 41-year-old man diagnosed with hairy cell leukemia developed a second malignancy that corresponded to a papillary cystic pancreatic tumor. The patient u...

journal_title：Pathology

authors： Acebo E,Rodilla IG,Torío B,Hernando M,García de Polavieja M,Morales D,Seco I,Bermudez A

更新日期：2000-08-01 00:00:00

abstract：AIMS:We aimed to evaluate the effects of caffeic acid phenethyl ester (CAPE) on lithium (Li)-induced lung toxicity. METHODS:Twenty-two adult male Wistar albino rats weighing between 280 and 300 g were used. The rats were randomly divided into three groups: control, Li and Li+CAPE groups. Li and CAPE were co-administer...

journal_title：Pathology

authors： Sahin O,Sulak O,Yavuz Y,Uz E,Eren I,Ramazan Yilmaz H,Malas MA,Altuntas I,Songur A

更新日期：2006-02-01 00:00:00

abstract：:The terminal complement complex has been implicated in the development of glomerular injury in both experimental and, indirectly, in human glomerulonephritis. Recent data suggests that the terminal complement complex in human glomerulonephritis may be in the cytolytically inactive SC5b-9 form which also contains S-pro...

journal_title：Pathology

authors： Murphy BF,Davies DJ,Morrow W,d'Apice AJ

更新日期：1989-10-01 00:00:00

abstract：:A strain of Serratia marcescens, isolated from the blood cultures of a patient receiving antibiotics, exhibited 3 unstable properties. These properties were resistance to aminoglycosides, colony size and pigment production. While resistance to aminoglycosides was linked to colony size, pigment production appeared inde...

journal_title：Pathology

authors： Ruhen RW,Wetherall FM

更新日期：1983-01-01 00:00:00

abstract：:Lysosome-associated membrane protein-1 (LAMP1) has been suggested to play complicated roles in cancer development and metastasis. The aim of this study was to explore the expression of LAMP1 in laryngeal squamous cell carcinoma (LSCC) and investigate the relationship between LAMP1 expression and clinicopathological ch...

journal_title：Pathology

authors： Lu M,Zhu H,Wang X,Zhang D,Xiong L,Zhu J,Mao Y,Qiang J

更新日期：2016-12-01 00:00:00

abstract：AIM:Both hypoxia inducible factor 1 (HIF-1) and basic fibroblast growth factor (bFGF) play important roles in tumour angiogenesis. This study was designed to clarify the cooperative effect of these two mediators in induction of vascular endothelial cell growth factor (VEGF) release from breast cancer and probe possible...

journal_title：Pathology

authors： Shi YH,Bingle L,Gong LH,Wang YX,Corke KP,Fang WG

更新日期：2007-08-01 00:00:00

abstract：:Human glomerular basement membrane (GBM) emulsified in Freund's complete adjuvant was injected into 16 Holtzman rats. Eleven (69%) of them subsequently developed glomerulonephritis. This disease was characterized by glomerular changes which included focal lobular hypercellularity due to localized hyperplasia of intrac...

journal_title：Pathology

authors： McCausland IP,Herdson PB,Gavin JB

更新日期：1976-04-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is currently regarded as a myeloid neoplasm, with remarkably broad clinical spectrum, ranging from isolated skin or bone lesions to a disseminated disease that can involve nearly any organ. LCH is generally regarded as a sporadic disease that occurs predominantly in the paediatric p...

journal_title：Pathology

authors： El Demellawy D,Young JL,de Nanassy J,Chernetsova E,Nasr A

更新日期：2015-06-01 00:00:00

abstract：:Soft tissue tumours are relatively rare, but are diagnostically challenging as they comprise a large spectrum of diagnostic entities. Substantial advances have been made in recent years in identifying the underlying recurrent chromosomal and genomic alterations in a significant subset of soft tissue tumours, and this ...

journal_title：Pathology

authors： Schaefer IM,Fletcher CDM

更新日期：2018-01-01 00:00:00

abstract：:In various tumor types dentritic cell, infiltration and the presence of tumor-infiltrating lymphocytes have been associated with an improved clinical outcome. In the uterine cervix these immunocompetent cells have been associated with improved prognosis in high stage disease. The current study examines the significanc...

journal_title：Pathology

authors： Bethwaite PB,Holloway LJ,Thornton A,Delahunt B

更新日期：1996-11-01 00:00:00

abstract：:The sections in the following review cover six main neurodegenerative diseases. The first article on Alzheimer's disease (AD) outlines the major evidence available to date that links Aβ-amyloid peptide as a proximal cause of AD. The article also highlights how an initial finding of the protein content of the amyloid p...

journal_title：Pathology

authors： Masters CL,Kril JJ,Halliday GM,Pamphlett R,Collins S,Hill AF,McLean C

更新日期：2011-02-01 00:00:00

abstract：:Solitary fibrous tumour (SFT) is well-described in the urinary tract, but malignant examples are rare. We studied our experience with high grade malignant SFT of the prostate to address the degree of histological and immunophenotypical overlap with sarcomatoid carcinoma and prostatic stromal sarcoma. Four cases were i...

journal_title：Pathology

authors： Bakhshwin A,Berry RS,Cox RM,Li R,Reynolds JP,Rubin BP,McKenney JK

更新日期：2020-10-01 00:00:00

abstract：:The pathological findings in a retrospective review of 100 consecutive intracranial stereotactic biopsies are presented. Definite diagnosis could be established in the majority (89) of cases and included 85 neoplasms (69 primary cerebral tumors, 10 non-Hodgkin's lymphomas and 6 metastases) and 4 non-neoplastic process...

journal_title：Pathology

authors： Robbins PD,Yu LL,Lee M,Stokes BA,Thomas GW,Watson P,Wong G

更新日期：1994-10-01 00:00:00

abstract：:The values of a number of biochemical variables have been studied before and after a 50-gram load of glucose orally. Reductions which were statistically significant were found for sodium, potassium, urea, total protein, albumin, calcium, phosphorus, urate, bilirubin, alkaline phosphatase, but not for bicarbonate, crea...

journal_title：Pathology

authors： Masarei JR

更新日期：1977-01-01 00:00:00

abstract：AIMS:Malakoplakia is a characteristic inflammatory condition which is usually seen in the urogenital tract. Gastrointestinal malakoplakia is seen in association with a variety of conditions such as ulcerative colitis, diverticular disease, adenomatous polyps and carcinoma. The purpose of this paper is to report four ad...

journal_title：Pathology

authors： Pillay K,Chetty R

更新日期：2002-08-01 00:00:00

abstract：:A histopathological examination was made of 60 stapes obtained during surgery for clinical otosclerosis. The findings, correlated with the clinical history and macroscopic appearances of the stapes, led to the following observations. The histological extent of the focus of otosclerosis agrees well with the macroscopic...

journal_title：Pathology

authors： Iyer PV,Gristwood RE

更新日期：1984-01-01 00:00:00

abstract：:A new three-tiered Pattern Classification system for usual-type endocervical adenocarcinomas (U-EACs) recommends using tumour invasive patterns rather than depth of invasion (DOI) and horizontal spread to categorise tumours. Tumours categorised by Pattern Classification are associated with lymph node (LN) metastasis a...

journal_title：Pathology

authors： Xu H,Pan H,Wang Y,Zhang J

更新日期：2019-10-01 00:00:00

abstract：AIM:Gasdermin-like (GSDML) is a novel member of the cancer associated gasdermin-domain containing (GSDMDC) protein family. The GSDMDC family has been linked to cancer development and progression, and this is the first study analysing the expression and intracellular localisation of GSDML. METHODS:GSDML gene transcript...

journal_title：Pathology

authors： Carl-McGrath S,Schneider-Stock R,Ebert M,Röcken C

更新日期：2008-01-01 00:00:00

abstract：:A screening method is described for urinary 3-methoxy-4-hydroxy mandelic acid using an initial ion exchange procedure, vanillin formation and extraction into toluene. The technique, is simple, rapid and specific, with a reference value up to 35 mumol (7.0 mg)/day established on 92 normal human subjects. Over 200 patie...

journal_title：Pathology

authors： Rumble BA,Dick M

更新日期：1978-01-01 00:00:00

abstract：:Ethanol in blood was assayed by 2 currently available procedures: a commercial kit enzymatic assay and a gas chromatographic procedure. Both methods were performed with commercially available materials and equipment. Results by the 2 procedures agreed well. For the 192 specimens studied, the correlation coefficient wa...

journal_title：Pathology

authors： Taylor GF,Turrill GH,Carter NG

更新日期：1984-04-01 00:00:00

abstract：:Co-operation by outside centres has made it possible to offer bone marrow chromosome analysis to patients living up to 1800 kilometres from the central cytogenetics laboratory. Diagnostic karyotypes have been obtained in 9 of 10 bone marrow specimens which were partially processed before being transported to the city ...

journal_title：Pathology

authors： Bell JA

更新日期：1978-07-01 00:00:00

abstract：AIMS:Sirtuin1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent deacetylase. Recently, some studies have suggested that SIRT1 could be over-expressed in breast, prostate and colon cancers and up-regulated SIRT1 inactivates p53 by deacetylation. Therefore, we investigated the prevalence and the prognostic impact ...

journal_title：Pathology

authors： Jang KY,Kim KS,Hwang SH,Kwon KS,Kim KR,Park HS,Park BH,Chung MJ,Kang MJ,Lee DG,Moon WS

更新日期：2009-01-01 00:00:00

abstract：:Decreased neutrophil alkaline phosphatase (NAP) synthesis is a classical feature of Philadelphia (Ph) positive chronic phase chronic myeloid leukemia (CML). Whether this aberration is an integral leukemic property of the cell or results from mediation by other factors is unclear. During alpha-interferon (alpha-IFN) ba...

journal_title：Pathology

authors： Taylor DL,Kerwick AM,Elliott SL,Rodwell RL,Wright SJ,Marlton PV,Veleba AR,Taylor KM

更新日期：1993-10-01 00:00:00

abstract：:Certain diagnoses in dermatopathology have significant implications for patient management and on occasion appropriate clinical care may be facilitated by a phone call from the reporting dermatopathologist to the referring doctor. Whether this is appropriate depends on a number of factors. The concept of 'critical dia...

journal_title：Pathology

authors： Korbl JD,Wood BA,Harvey NT

更新日期：2018-04-01 00:00:00

abstract：AIMS:Serum cobalamin (cbl, vitamin B(12)) tests are routinely ordered for investigating conditions potentially amenable to cbl supplementation. This study aimed to systematically assess the evidence of diagnostic accuracy for serum cbl tests across patient subgroups. METHODS:Seven medical databases were searched (1990...

journal_title：Pathology

authors： Willis CD,Elshaug AG,Milverton JL,Watt AM,Metz MP,Hiller JE,ASTUTE Health Study Group.

更新日期：2011-08-01 00:00:00

abstract：:Five cases of intraductal papillary-mucinous neoplasm (IPMN) of the pancreas are here described. This group of tumors represents a distinct clinicopathological entity with characteristic endoscopic, radiological, gross and microscopic appearances. Our five cases all showed marked dilatation of the main pancreatic duct...

journal_title：Pathology

authors： Kench JG,Eckstein RP,Smith RC

更新日期：1997-02-01 00:00:00

abstract：:Understanding human genetic variation and how it impacts on gene function is a major focus in genomic-based research. Translation of this knowledge into clinical care is exemplified by pharmacogenetics/pharmacogenomics. The identification of particular gene variants that might influence drug uptake, metabolism, distri...

journal_title：Pathology

authors： Trent RJ,Cheong PL,Chua EW,Kennedy MA

更新日期：2013-06-01 00:00:00

abstract：AIM:1) To determine the prevalence of hepatitis B in Sydney autopsies and 2) to determine the relationship between seroprevalence, hepatitis B risk factors and histological changes in the liver. METHODS:One hundred autopsy subjects were studied for evidence of past or present hepatitis B infection, using RIA to detect...

journal_title：Pathology

authors： Ashwell MJ,Cossart YE

更新日期：1995-01-01 00:00:00

abstract：:Cervical biopsies obtained by colposcopic direction from 358 women were histologically examined for squamous dysplasia (cervical intra-epithelial neoplasia; CIN) and human papillomavirus (HPV) infection. Of the 358 biopsies, 136 were stained by an immunoperoxidase method using an antiserum against genus-specific (comm...

journal_title：Pathology

authors： Sterrett GF,Alessandri LM,Pixley E,Kulski JK

更新日期：1987-01-01 00:00:00

abstract：:One hundred and two cases of benign nerve sheath tumors (NSTs) were studied with a combined approach using routine light microscopy (LM), immunohistochemistry (IH) for myelin basic protein (MBP) and S-100 protein as well as transmission electron microscopy (TEM) with the aim of obtaining greater insight into the true ...

journal_title：Pathology

authors： Sharma S,Sarkar C,Mathur M,Dinda AK,Roy S

更新日期：1990-10-01 00:00:00