Early and late effects of wound healing on development of colon tumours in a model of colon carcinogenesis by 1,2-dimethylhydrazine in the rat.

abstract：:One hundred and two cases of benign nerve sheath tumors (NSTs) were studied with a combined approach using routine light microscopy (LM), immunohistochemistry (IH) for myelin basic protein (MBP) and S-100 protein as well as transmission electron microscopy (TEM) with the aim of obtaining greater insight into the true ...

journal_title：Pathology

authors： Sharma S,Sarkar C,Mathur M,Dinda AK,Roy S

更新日期：1990-10-01 00:00:00

abstract：:Partial regression is common in cutaneous melanoma; however, complete regression manifesting as tumoural melanosis is rare, conceptually challenging and under-reported. In this study we report on clinical, histological and molecular findings in four cases of completely regressed cutaneous melanoma with nodal or brain ...

journal_title：Pathology

authors： Ching D,Amini E,Harvey NT,Wood BA,Mesbah Ardakani N

更新日期：2019-06-01 00:00:00

abstract：:Tumour infiltrating lymphocytes in primary melanoma have been found to correlate with patient outcomes. A subpopulation of tumour infiltrating lymphocytes expresses the transcription factor forkhead box protein 3 (FOXP3). These are known as FOXP3+ T-regulatory cells (Tregs) and are thought to play an immune suppressiv...

journal_title：Pathology

authors： Leslie C,Bowyer SE,White A,Grieu-Iacopetta F,Trevenen M,Iacopetta B,Amanuel B,Millward M

更新日期：2015-10-01 00:00:00

abstract：:An epidemiological study of childhood cancer in New Zealand identified 409 children aged 0 to 14 years with malignant neoplasms newly diagnosed between 1990 and 1993 inclusive. The original microscopic material on which the diagnoses were based was reviewed in 398 cases and the neoplasms were allocated into the 12 maj...

journal_title：Pathology

authors： Becroft DM,Dockerty JD,Berkeley BB,Chan YF,Lewis ME,Skeen JE,Synek BJ,Teague LR

更新日期：1999-05-01 00:00:00

abstract：:Recent updated models of the coagulation mechanism suggest that factor VII/thromboplastin complex is the main initiator or trigger of coagulation. Factor VII activation of factor IX is likely to be an important activation pathway. Inhibition of factor VII by tissue factor pathway inhibitor may have a regulatory role i...

journal_title：Pathology

authors： Wei DC,Wong RW,Robertson EP

更新日期：1997-05-01 00:00:00

abstract：:The BRAF(V600E) mutation confers worse prognosis to metastatic colorectal cancer (mCRC) patients. In addition, this mutation has a negative predictive value for response to treatment with monoclonal antibodies against EGFR in patients with KRAS wild-type (wt) mCRC. The utility of immunohistochemistry (IHC) as an alter...

journal_title：Pathology

authors： Ilie MI,Long-Mira E,Hofman V,Mouroux J,Vignaud JM,Gauchotte G,Begueret H,Merlio JP,Emile JF,Hébuterne X,Hofman P

更新日期：2014-06-01 00:00:00

abstract：:Sex cord-stromal tumours (SCSTs) consist of a heterogeneous group of neoplasms with diverse clinicopathological features and biological behaviour. They often present as a diagnostic challenge as they have varied and occasionally overlapping histomorphology and some may even mimic non-SCSTs. An accurate diagnosis is im...

journal_title：Pathology

authors： Lim D,Oliva E

更新日期：2018-02-01 00:00:00

abstract：:Examination of routinely stained haematoxylin and eosin sections may sometimes prove inadequate in differentiating partial hydatidiform moles (PHM) from complete hydatidiform moles (CHM). While cytogenetic analysis can aid in the distinction, such facilities are not always available. The possibility of using immunohis...

journal_title：Pathology

authors： Cheah PL,Looi LM

更新日期：1994-04-01 00:00:00

abstract：:Chromosome identification techniques have shown the non-random nature of cytogenetic changes in leukemia. In addition, they have identified structural chromosome abnormalities occurring in specific types of acute leukemia as classified by the FAB criteria. Such cytogenetic sub groups are associated with differing prog...

journal_title：Pathology

authors： Garson OM

更新日期：1982-07-01 00:00:00

abstract：:The present conventional methods for determination of Hemoglobin (Hb) concentration in whole blood depend on the direct colorimetric measurement of chemically modified Hb following its release from red cells by lysis. This paper examines an alternative, indirect method which does not require initial red cell lysis, co...

journal_title：Pathology

authors： Kalache GR,Sartor MM,Hughes WG

更新日期：1991-04-01 00:00:00

abstract：:Five cases of intraductal papillary-mucinous neoplasm (IPMN) of the pancreas are here described. This group of tumors represents a distinct clinicopathological entity with characteristic endoscopic, radiological, gross and microscopic appearances. Our five cases all showed marked dilatation of the main pancreatic duct...

journal_title：Pathology

authors： Kench JG,Eckstein RP,Smith RC

更新日期：1997-02-01 00:00:00

abstract：:Contamination of cell cultures for virus isolation has been increasingly encountered. By reviewing and changing the antimicrobials incorporated in cell culture media, we aim to control this problem. Contaminated cell culture fluids were inoculated for bacterial and fungal isolation, identification and antibacterial su...

journal_title：Pathology

authors： Lo JY,Lim WW,Tam BK,Lai MY

更新日期：1996-11-01 00:00:00

abstract：AIMS:There are many variants of papillary carcinoma, and some of these variants have been reported to show biological behaviours differing from that of conventional papillary carcinoma. In this study, we present our experience regarding the prevalence and prognoses of these variants of papillary carcinoma. METHODS:H&E...

journal_title：Pathology

authors： Ito Y,Hirokawa M,Uruno T,Kihara M,Higashiyama T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Miyauchi A

更新日期：2008-10-01 00:00:00

abstract：AIMS:BRAF mutation has been shown in a large meta-analysis to be an independent prognostic marker for papillary thyroid carcinoma (PTC) with poorer survival and higher recurrence rates. METHODS:We studied prevalence of BRAF mutation in 77 patients with PTC from an Australian cohort using competitive polymerase chain r...

journal_title：Pathology

authors： McKelvie PA,Chan F,Yu Y,Waring P,Gresshoff I,Farrell S,Williams RA

更新日期：2013-12-01 00:00:00

abstract：:The aim of the present study is to describe the histological and mutational characteristics of a series of both large and small bowel adenocarcinomas in patients with Crohn's disease from a tertiary referral centre of inflammatory bowel disease. Bowel adenocarcinoma was diagnosed in 11 (1.7%) of 660 consecutive patien...

journal_title：Pathology

authors： Malvi D,Vasuri F,Mattioli B,Gruppioni E,Fiorentino M,Gionchetti P,Grigioni WF,Poggioli G,D'Errico-Grigioni A

更新日期：2014-08-01 00:00:00

abstract：:Soft tissue tumours are relatively rare, but are diagnostically challenging as they comprise a large spectrum of diagnostic entities. Substantial advances have been made in recent years in identifying the underlying recurrent chromosomal and genomic alterations in a significant subset of soft tissue tumours, and this ...

journal_title：Pathology

authors： Schaefer IM,Fletcher CDM

更新日期：2018-01-01 00:00:00

abstract：:Apoptosis in the myocardium is complex and often difficult to recognise. Myocyte apoptosis is scattered across the myocardial wall and is restricted to individual cells. In the present study, we describe the amount of apoptosis in 50 endomyocardial biopsies taken from 50 patients with dilated cardiomyopathy, in 14 hea...

journal_title：Pathology

authors： Kavantzas NG,Lazaris AC,Agapitos EV,Nanas J,Davaris PS

更新日期：2000-08-01 00:00:00

abstract：:A cerebral neuroblastoma was studied by light microscopy, tissue culture and electron microscopy. Synapse-like structures were found within tumour cells. This supports the neuroectodermal origin of this neoplasm. ...

journal_title：Pathology

authors： Ojeda VJ,Jacobsen PF,Papadimitriou JM

更新日期：1980-04-01 00:00:00

abstract：AIMS:Pancreatic endocrine tumours (PET) containing ductules are an uncommon histological variant. Considerable conjecture surrounds the origin and histogenesis of the ductules. Opinions range from the ductules being an inherent part of the tumour, to others who feel they are merely entrapped. A study of 21 cases of thi...

journal_title：Pathology

authors： Chetty R,Serra S,Asa SL,Volkan Adsay N

更新日期：2006-02-01 00:00:00

abstract：:Ebolaviruses, and the other viral causes of haemorrhagic fevers (VHF) have always posed special problems for diagnostic laboratories. These arise from the rarity of human infections, minimal documented experience with test delivery and interpretation, the paucity of established commercial or in-house assays, the lack ...

journal_title：Pathology

authors： Smith DW,Rawlinson WD,Kok J,Dwyer DE,Catton M

更新日期：2015-08-01 00:00:00

abstract：:An elderly woman had a cerebral gliosarcoma with a single pulmonary metastasis, together with a separate pulmonary adenoid-cystic carcinoma. Spontaneous extraneural metastases of primary intracranial neoplasms are exceedingly unusual; so far, only 8 proven cases are recorded in the English language medical literature....

journal_title：Pathology

authors： Ojeda VJ,Sterrett GF

更新日期：1984-04-01 00:00:00

abstract：:Gene targeting ('knock-out') technology is now widely used in the basic science of all disciplines of pathology and particularly auto-immune and inflammatory disease. Gene targeting is the wilful introduction of precise mutations into the genome of an animal, usually a mouse, affecting the function of a single gene or...

journal_title：Pathology

authors： Riminton DS

更新日期：2002-04-01 00:00:00

abstract：:An enzyme-immunoassay has been developed for rapid isotyping of murine monoclonal antibodies. This assay has several advantages over the commonly used typing methods. It does not require the presence of specific antigen. Typing plates can be prepared in advance and stored frozen. Unequivocal results can be obtained in...

journal_title：Pathology

authors： Gardner ID

更新日期：1985-01-01 00:00:00

abstract：:The failure of N. gonorrhoeae to grow on isolation media was found to be due to inhibitory substances present in commercially available horse sera. Subsequent investigations indicated that the inhibitory action of the horse serum may have been due to antibodies to N. gonorrhoeae, H. influenzae, H. parainfluenzae and b...

journal_title：Pathology

authors： Mugg PA,Hill A

更新日期：1984-07-01 00:00:00

abstract：:The clinical course and biopsy findings of twenty-one patients with IgA nephropathy, followed up for a mean period of 37.4 mth (range 24-54 mth) after diagnosis, were reviewed retrospectively to determine whether the clinical presentations, the laboratory findings or histopathologic changes have prognostic implication...

journal_title：Pathology

authors： Ng WL,Loke SL,Yeung CK,Kwan S,Chan KW,Chan MK

更新日期：1986-01-01 00:00:00

abstract：:Oral cancer is a serious public health problem, with over 200,000 new cases reported annually worldwide, two-thirds of which occur in developing countries. The overall mortality rate for intra-oral cancer remains high at approximately 50%, even with modern medical services, probably due to the advanced stage of the di...

journal_title：Pathology

authors： Walker DM,Boey G,McDonald LA

更新日期：2003-10-01 00:00:00

abstract：:The frequency of simultaneous infection with Neisseria gonorrhoeae and Chlamydia trachomatis in men and women in Eastern Sydney was examined prospectively over a 21 month period in patients from whom appropriate specimens were obtained. In men gonococcal disease (113 cases) and chlamydial infections (124 cases) occurr...

journal_title：Pathology

authors： Tapsall JW,Kinchington M

更新日期：1996-01-01 00:00:00

abstract：:A 14 yr old girl presented with a large cystic mass in the transverse mesocolon which was completely excised. Cystic lymphangioma was diagnosed, based on the specific histologic, immunoperoxidase and ultrastructural findings. ...

journal_title：Pathology

authors： Yuen ST,Ng IO,Ho J,Ma L

更新日期：1992-07-01 00:00:00

abstract：:A calcified nodule on the liver of a 62-year-old man from North Carolina, USA, contained a degenerated nymph of Linguatula serrata. The nodule was incidentally discovered at laparotomy for malignant lymphoma and cholelithiasis. The cuticle was all that remained of the parasite, but sclerotized openings and large spine...

journal_title：Pathology

authors： Baird JK,Kassebaum LJ,Ludwig GK

更新日期：1988-04-01 00:00:00

abstract：:Renal cell carcinoma (RCC) generally has a poor prognosis because of late diagnosis and metastasis. We have previously described decreased tumour necrosis factor receptor-associated factor-1 (TRAF-1) in RCC compared with paired normal kidney in a patient cohort in Australia. In the present study, TRAF-1 expression in ...

journal_title：Pathology

authors： Rajandram R,Yap NY,Pailoor J,Razack AH,Ng KL,Ong TA,Morais C,Gobe GC

更新日期：2014-10-01 00:00:00