Expression of catenins and p120cas in melanocytic nevi and cutaneous melanoma: deficient alpha-catenin expression is associated with melanoma progression.

abstract：:Malignant pleural mesothelioma (MPM) is often associated with a poor prognosis and options for the treatment of this disease are few. To date, the important role of the immune microenvironment in modifying the disease natural history is well established. The programmed cell death pathway (PD-1/PD-L1) limits the T lymp...

journal_title：Pathology

authors： Rrapaj E,Giacometti L,Spina P,Salvo M,Baselli GA,Veggiani C,Rena O,Trisolini E,Boldorini RL

更新日期：2020-11-30 00:00:00

abstract：AIMS:In our previous studies, comparative proteomics demonstrated that lactate dehydrogenase B subunit (LDH-B) is down-regulated in high grade compared to non-high grade urinary bladder urothelial carcinoma (UBUC). However, this finding has not been validated by clinical cohort investigation. Therefore, in the present ...

journal_title：Pathology

authors： Liao AC,Li CF,Shen KH,Chien LH,Huang HY,Wu TF

更新日期：2011-12-01 00:00:00

abstract：:Renal biopsies were obtained from 23 patients at the time of orthotopic liver transplantation. Twelve biopsies showed minor glomerular abnormalities, 2 exhibited IgA nephropathy and one showed mesangiocapillary glomerulonephritis type I. The remaining 8 patients had glomerular lesions diagnosed as hepatic glomeruloscl...

journal_title：Pathology

authors： Axelsen RA,Crawford DH,Endre ZH,Lynch SV,Balderson GA,Strong RW,Fleming SJ

更新日期：1995-07-01 00:00:00

abstract：AIMS:To examine the impact of microwave (MW) tissue processing on turnaround times (TATs) in a routine diagnostic laboratory. METHODS:A retrospective review of TATs for tissue processing (specimen receipt to completion of H&E-stained section) and pathologists' report generation (receipt of stained section to validatio...

journal_title：Pathology

authors： Leong AS,Price D

更新日期：2004-08-01 00:00:00

abstract：:Rare tumours are a heterogeneous group of conditions that encompass benign to malignant lesions both of stromal and epithelial origin. Here some of these tumours are described, in which the authors have most familiarity. An outline of medullary carcinoma is also presented. ...

journal_title：Pathology

authors： Foschini MP,Eusebi V

更新日期：2009-01-01 00:00:00

abstract：:A genetic variant of antithrombin with impaired heparin cofactor activity was identified in 4 members of a French family. Both the variant and normal antithrombin component were purified by affinity chromatography on heparin Sepharose. Reverse phase peptide mapping revealed a single altered peak when tryptic digests o...

journal_title：Pathology

authors： Brennan SO,Borg JY,Shaw GJ,Caen J,George PM

更新日期：1991-01-01 00:00:00

abstract：:A 14 yr old girl presented with a large cystic mass in the transverse mesocolon which was completely excised. Cystic lymphangioma was diagnosed, based on the specific histologic, immunoperoxidase and ultrastructural findings. ...

journal_title：Pathology

authors： Yuen ST,Ng IO,Ho J,Ma L

更新日期：1992-07-01 00:00:00

abstract：:In 50 necropsies on leukaemic children, the major cause of death was infection. In patients dying during therapy for induction or reinduction of remission, the most frequent infection was a distinctive neutropenic enterocolitis or typhlitis. This was seen in 46% of the whole series and was a major factor in the death ...

journal_title：Pathology

authors： Moir DH,Bale PM

更新日期：1976-07-01 00:00:00

abstract：AIMS:Hep Par 1 has been described as a specific marker of hepatocellular differentiation and its immunohistochemical use has been suggested as a helpful tool for hepatocellular carcinoma (HCC) diagnosis. Most metastatic liver tumours come from the gastrointestinal tract and usually can be distinguished from HCC only th...

journal_title：Pathology

authors： Villari D,Caruso R,Grosso M,Vitarelli E,Righi M,Barresi G

更新日期：2002-10-01 00:00:00

abstract：:This retrospective study evaluated 15,377 sets of BacT/Alert blood cultures to determine incubation time for blood cultures. Ninety-six per cent (1476) of total isolates signalled positive within five days and 56 isolates turned positive in five to seven days. Of the 56 organisms recovered between five and seven days,...

journal_title：Pathology

authors： Mukerjee C,Heron LG,Varettas K

更新日期：1998-05-01 00:00:00

abstract：:We report here on the usefulness of the 14C-serotonin release assay for the laboratory confirmation of the clinical diagnosis of heparin-induced thrombocytopenia syndrome (HITS). Over the past 3 yrs, some 140 individual serum samples have been tested in our laboratory for heparin-associated anti-platelet activity ('he...

journal_title：Pathology

authors： Favaloro EJ,Bernal-Hoyos E,Exner T,Koutts J

更新日期：1992-07-01 00:00:00

abstract：:Atypical teratoid/rhabdoid tumours (AT/RTs) are rare, highly malignant tumours of the central nervous system (CNS) with poor prognosis that usually affect young children. The aim of this study was to assess the clinicopathological features and prognostic factors of AT/RTs. Here, we describe the clinicopathological and...

journal_title：Pathology

authors： Wang RF,Guan WB,Yan Y,Jiang B,Ma J,Jiang MW,Wang LF

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Ethanol is teratogenic, interferes with folic acid and is extensively used by young women. Our objective was to determine the effects of ethanol and/or folate deficiency on mouse fetuses. METHOD:In Experiment 1, pregnant mice receiving a commercial diet were divided into three groups: control (C), low eth...

journal_title：Pathology

authors： Gutierrez CM,Ribeiro CN,de Lima GA,Yanaguita MY,Peres LC

更新日期：2007-10-01 00:00:00

abstract：:Patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) often exhibit clonal chromosomal abnormalities. Using a probe for the centromeric region of chromosome 8, fluorescence in situ hybridization (FISH) on interphase cells was used to detect trisomy 8 in an AML patient whose leukemia was characte...

journal_title：Pathology

authors： White DL,Hutchins CJ,Turczynowicz S,Suttle J,Haylock DN,Hughes TP,Juttner CA,To LB

更新日期：1997-08-01 00:00:00

abstract：AIM:To determine whether the common respiratory pathogen, Chlamydia pneumoniae, was associated with atherosclerotic plaques in Australian subjects. METHODS:A total of 29 coronary atherosclerotic lesions and 18 normal coronary arterial samples were tested for the presence of C. pneumoniae by PCR and immunofluorescence ...

journal_title：Pathology

authors： Cochrane M,Kalle WH,Roffey P,Moriarty HT

更新日期：2002-06-01 00:00:00

abstract：:The morphology of livers of Wistar rats treated with beta-carotene (BC), vitamin A (VA, retinol acetate) or corn oil (CO, controls) and submitted to the resistant hepatocyte model of carcinogenesis was studied. Preneoplastic lesions (PNL) were smaller and less numerous in the BC group. The latter group also presented ...

journal_title：Pathology

authors： Dagli ML,Guerra JL,Sinhorini IL,Wu TS,Rizzi MB,Penteado MV,Moreno FS

更新日期：1998-08-01 00:00:00

abstract：:A new mucin antigen was detected in a mucinous cystadenoma of human ovary. An antiserum produced in rabbits against the crude cyst fluid, following appropriate absorptions, showed immunoreactivity exclusively with tumour epithelium, particularly endocervical type epithelium. The antigen responsible for the immunoreact...

journal_title：Pathology

authors： Ma J,Handley CJ,de Boer WG

更新日期：1983-10-01 00:00:00

abstract：:The clinical and laboratory features of a patient with a recently recognized new variant of von Willebrand's disease are presented. The importance of this variant is that it is associated with a clinically significant bleeding diathesis but with a normal skin bleeding time, PTTK, factor VIIIc and platelet aggregation ...

journal_title：Pathology

authors： Wylie B,Gibson J,Uhr E,Kronenberg H

更新日期：1988-01-01 00:00:00

abstract：:Four hundred and ten thyroid nodules, 127 breast lumps and 43 lymph nodes were sampled and analyzed to compare the classical aspiration (ASP) technique with the non aspiration needle jab (NASP) technique. The adequacy of cellularity, significant blood staining and the discomfort felt by the patient were assessed and s...

journal_title：Pathology

authors： Kumarasinghe MP,Sheriffdeen AH

更新日期：1995-10-01 00:00:00

abstract：:Recently, both the World Health Organization/International Agency for Research on Cancer (WHO/IARC) and the American Joint Committee on Cancer (AJCC) have classified oropharyngeal squamous cell carcinoma (OPSCC) on the basis of HPV status. For this purpose, the WHO/IARC recommended direct molecular HPV testing. In pra...

journal_title：Pathology

authors： Veyer D,Wack M,Grard O,Bonfils P,Hans S,Bélec L,Badoual C,Péré H

更新日期：2019-06-01 00:00:00

abstract：AIMS:INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ). METHODS:INI1 was determined by immunohistochemistry and MGMT by methylation-specific PCR. RESULTS...

journal_title：Pathology

authors： Zunarelli E,Bigiani N,Sartori G,Migaldi M,Sgambato A,Maiorana A

更新日期：2011-01-01 00:00:00

abstract：:A fatal case of multiple sulfatase deficiency in a 10-year-old girl is reported. In this rare disease, which is inherited as an autosomal recessive, features of metachromatic leukodystrophy and of mucopolysaccharidoses occur together. The white matter suffers progressive destruction with sulfatides accumulating in mac...

journal_title：Pathology

authors： Kepes JJ,Berry A 3rd,Zacharias DL

更新日期：1988-07-01 00:00:00

abstract：:Various tumour markers have been evaluated in malignant pleural effusions, but not CD66c. This study evaluated the diagnostic ability of CD66c in lung adenocarcinoma-associated malignant pleural effusions (LA-MPEs) and compared it with other known tumour markers. Forty-seven cases of LA-MPE and 52 cases of benign pleu...

journal_title：Pathology

authors： Son SM,Han HS,An JY,Choe KH,Lee KM,Lee KH,Kim SS,Lee YM,Lee HC,Song HG,Lee OJ

更新日期：2015-02-01 00:00:00

abstract：:Proliferation of isolated hepatocytes in long-term splenic implants was assessed by flash labelling with a 1 pulse of tritiated thymidine (3H TdR). Cell kinetics showed that the basal labelling index was 0.9% which was greater than normal non-regenerating liver. Twenty four hours following partial hepatectomy the labe...

journal_title：Pathology

authors： Gupta S,Johnstone R,Darby H,Selden C,Price Y,Hodgson HJ

更新日期：1987-01-01 00:00:00

abstract：:Rapid rescreening was established in our laboratory in 1995, following the publication of several studies indicating improved sensitivity for the detection of abnormalities in cervical smears. During the study period, 285,841 negative smears (representing 89.09% of the total workload) were rapidly rescreened. A total ...

journal_title：Pathology

authors： Wright RG,Halford JA,Ditchmen EJ

更新日期：1999-11-01 00:00:00

abstract：:A patient with cerebral strokes had a cardiac tumour excised. Histologically, it was an infarcted myxoma with features of a Gamna body. Findings are compared with other cardiac Gamna bodies reported in the literature. Most probably represent unusual degenerative changes in a myxoma. ...

journal_title：Pathology

authors： Coard KC,Silver MD

更新日期：1984-10-01 00:00:00

abstract：:Rheumatoid Arthritis (RA) synovial membranes were examined by single and dual immunohistological techniques with a number of monoclonal antibodies against lymphocyte and macrophage related antigens. CD4 positive T lymphocytes frequently expressed MHC Class II antigens and were found in sublining collections in close a...

journal_title：Pathology

authors： Smith MD,O'Donnell J,Highton J,Palmer DG,Rozenbilds M,Roberts-Thomson PJ

更新日期：1992-01-01 00:00:00

abstract：AIMS:An important consideration in the design of a tumour vaccine is the ability of tumour-specific cytotoxic T lymphocytes (CTL) to recognise unmanipulated tumour cells in vivo. To determine whether B-CLL might use an escape strategy, the current studies compared B-CLL and normal B cell MHC class I expression. METHOD...

journal_title：Pathology

authors： Juffs H,Fowler N,Saal R,Grimmett K,Beasley S,O'Sullivan B,Frazer I,Gill D,Thomas R

更新日期：2004-02-01 00:00:00

abstract：:About 10% of gastric carcinomas are associated with Epstein-Barr virus (EBV), which are defined as EBV-associated gastric carcinomas (EBVaGCs). EBVaGCs are usually accompanied by massive lymphocytes infiltration, among which CD8+ T cells are predominant. To date, the apoptosis of the infiltrating CD8+ T cells in EBVaG...

journal_title：Pathology

authors： Tang F,Chen JN,Zhang NN,Gong LP,Jiang Y,Feng ZY,Xiao L,Li HG,Du H,Wu B,Shao CK

更新日期：2018-10-01 00:00:00

abstract：AIM:Performance measures for Australian laboratories reporting cervical cytology are a set of quantifiable measures relating to the profile and accuracy of reporting. This study reviews aggregate data collected over the ten years in which participation in the performance measures has been mandatory. METHODS:Laboratori...

journal_title：Pathology

authors： Shield PW,Finnimore J,Cummings M,Wright RG

更新日期：2010-12-01 00:00:00