Abstract:
OBJECTIVE:Platelet counts generated by automated analyzers on blood specimens that contain platelet clumps are often inaccurate and require verification by blood-smear review. In this study, we assessed the reliability of the Sysmex XE-5000 instrument to detect platelet clumps. METHOD:We reviewed automated complete blood count (CBC) results and the findings of the microscopic review of corresponding blood smears of 600 blood specimens specifically selected from the routine laboratory workload. The sensitivity, specificity, efficiency, positive predictive value (PPV), and negative predictive value (NPV) of its 2 platelet-associated flags (abnormal platelet-size distribution [PAD] flag and platelet-clumps [CLP] flag) were determined. RESULTS:The respective values for the sensitivity, specificity, efficiency, and PPV were 42%, 83%, 63%, and 1% for the PAD flag and 57%, 99%, 78%, and 37% for the CLP flag. The NPV was 100%. CONCLUSION:The overall reliability of the CLP flag is superior than that of the PAD flag but there is room for further improvement.
journal_name
Lab Medjournal_title
Laboratory medicineauthors
Hawkins J,Gulati G,Uppal G,Gong Jdoi
10.1093/labmed/lmw016subject
Has Abstractpub_date
2016-08-01 00:00:00pages
189-94issue
3eissn
0007-5027issn
1943-7730pii
lmw016journal_volume
47pub_type
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journal_title:Laboratory medicine
pub_type: 杂志文章
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journal_title:Laboratory medicine
pub_type: 杂志文章
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更新日期:2018-10-11 00:00:00
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journal_title:Laboratory medicine
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journal_title:Laboratory medicine
pub_type: 杂志文章,评审
doi:10.1093/labmed/lmaa049
更新日期:2021-01-04 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1309/LM604RQVKVLRFXOR
更新日期:2014-10-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmw044
更新日期:2016-11-01 00:00:00
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更新日期:2016-02-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmy075
更新日期:2019-07-16 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmx053
更新日期:2017-11-08 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmy073
更新日期:2019-07-16 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmw050
更新日期:2017-02-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmx064
更新日期:2017-12-22 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmy003
更新日期:2018-07-05 00:00:00
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pub_type: 杂志文章
doi:10.1093/labmed/lmw007
更新日期:2016-05-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz004
更新日期:2019-10-10 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz038
更新日期:2020-01-02 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmw069
更新日期:2017-08-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1309/LM7E5LG6PWJYEFUJ
更新日期:2015-07-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmw062
更新日期:2017-02-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz015
更新日期:2020-03-10 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmy026
更新日期:2018-07-05 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmw008
更新日期:2016-05-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz063
更新日期:2020-07-08 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz035
更新日期:2020-01-02 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz092
更新日期:2020-05-06 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章,多中心研究
doi:10.1093/labmed/lmy053
更新日期:2019-01-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmaa082
更新日期:2020-09-21 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmaa052
更新日期:2020-08-21 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1309/lm2xcv5sqml1ontm
更新日期:2014-04-01 00:00:00