Abstract:
:Waldenström macroglobulinemia (WM) is a form of lymphoplasmacytic lymphoma that can cause hyperviscosity syndrome due to unchecked monoclonal antibody production. Some patients are also found to have associated cryoglobulinemia, which can cause systemic complications including vasculitis, renal disease, and pulmonary complications. Cryoglobulins can also serve as a source of interference with various laboratory assays. Therapeutic plasma exchange (TPE) is one of the recommended treatment modalities to manage hyperviscosity. Herein, we present the case of an 84-year-old female patient with Waldenström macroglobulinemia who presented with hyperviscosity syndrome and discrepant laboratory findings, and who then developed transfusion-related acute lung injury (TRALI) during TPE. This case is one of many in the emerging possible linkages observed between cryoglobulinemia and TRALI.
journal_name
Lab Medjournal_title
Laboratory medicineauthors
Beech C,Kumar D,Hendrickson J,Perincheri S,Tormey C,Bahar Bdoi
10.1093/labmed/lmy073subject
Has Abstractpub_date
2019-07-16 00:00:00pages
313-319issue
3eissn
0007-5027issn
1943-7730pii
5292350journal_volume
50pub_type
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journal_title:Laboratory medicine
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更新日期:2017-02-01 00:00:00
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更新日期:2016-02-01 00:00:00
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更新日期:2020-08-20 00:00:00
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更新日期:2016-08-01 00:00:00
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更新日期:2016-08-01 00:00:00
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doi:10.1309/LM96EJPPBYADIOVC
更新日期:2015-10-01 00:00:00
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doi:10.1093/labmed/lmx064
更新日期:2017-12-22 00:00:00
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journal_title:Laboratory medicine
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doi:10.1093/labmed/lmz013
更新日期:2019-10-10 00:00:00
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doi:10.1093/labmed/lmz063
更新日期:2020-07-08 00:00:00
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更新日期:2020-12-07 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章,评审
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更新日期:2018-07-05 00:00:00
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doi:10.1093/labmed/lmy075
更新日期:2019-07-16 00:00:00
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更新日期:2018-07-05 00:00:00
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doi:10.1093/labmed/lmaa069
更新日期:2020-10-03 00:00:00
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journal_title:Laboratory medicine
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doi:10.1093/labmed/lmx077
更新日期:2018-03-21 00:00:00
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更新日期:2014-07-01 00:00:00
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更新日期:2017-02-01 00:00:00
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doi:10.1309/LM7E5LG6PWJYEFUJ
更新日期:2015-07-01 00:00:00
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doi:10.1093/labmed/lmy021
更新日期:2018-07-05 00:00:00
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更新日期:2017-02-01 00:00:00
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journal_title:Laboratory medicine
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doi:10.1093/labmed/lmz035
更新日期:2020-01-02 00:00:00
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更新日期:2017-08-01 00:00:00
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更新日期:2016-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1309/LMKT4P9FFI2BBSIU
更新日期:2015-01-01 00:00:00