Proof of Concept for a Polyethylene Glycol/Gel Hybrid Testing Method.

abstract：OBJECTIVE:Tyrosine kinase inhibitors (TKIs) are considered standard first-line treatment in patients with chronic myeloid leukemia. Because ABL kinase domain mutations are the most common causes of treatment resistance, their prevalence and assessment during treatment may predict subsequent response to therapy. METHOD...

journal_title：Laboratory medicine

authors： Shojaei M,Rezvani H,Azarkeivan A,Poopak B

更新日期：2020-08-21 00:00:00

abstract：:Waldenström macroglobulinemia (WM) is a form of lymphoplasmacytic lymphoma that can cause hyperviscosity syndrome due to unchecked monoclonal antibody production. Some patients are also found to have associated cryoglobulinemia, which can cause systemic complications including vasculitis, renal disease, and pulmonary ...

journal_title：Laboratory medicine

authors： Beech C,Kumar D,Hendrickson J,Perincheri S,Tormey C,Bahar B

更新日期：2019-07-16 00:00:00

abstract：:Rhizobium radiobacter is an opportunistic, usually saprophytic, gram-negative bacillus found in agricultural soil. Isolation from blood has been reported most often in hospitalized patients harboring malignant neoplasms or human immunodeficiency virus (HIV) associated immunosuppression, who have catheter or medical de...

journal_title：Laboratory medicine

authors： Sawhney S,Naab T,Oneal P

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To evaluate broad-range 16S ribosomal DNA (rDNA) polymerase chain reaction (PCR) as a rapid screening tool to detect bacterial contamination of stem-cell products. METHODS:We performed the evaluation using whole blood spiked with serially diluted bacterial-type strains. Detection sensitivity was defined as t...

journal_title：Laboratory medicine

authors： Tokuno O,Hayakawa A,Yanai T,Mori T,Ohnuma K,Tani A,Minami H,Sugimoto T

更新日期：2015-01-01 00:00:00

abstract：:Myeloperoxidase (MPO) deficiency, one of the most common inherited phagocyte defects, and may exist as a transient phenomenon in combination with some clinical condition. Hematological analyzer ADVIA 2120i is used to identify the different types of leukocytes based on their size and staining properties, and by mean pe...

journal_title：Laboratory medicine

authors： Roh S,Ham JY,Song KE,Hwang N,Lee NY

更新日期：2020-03-10 00:00:00

abstract：:Herein, we present a case of extensive lymph node involvement by disseminated Cryptococcus infection developing in the immediate period after liver transplantation and initiation of immunosuppressive therapy. The patient, a 56 year old ethnicity unknown man, received a liver transplant for acute decompensated liver. B...

journal_title：Laboratory medicine

authors： Gilles SR,Arbefeville SS,Ferrieri P,Courville EL

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:The production of 2 monoclonal proteins characterizes biclonal gammopathic manifestations (BGMs). The available medical literature from India is chiefly restricted to case reports. OBJECTIVE:To study the incidence of BGMs in a tertiary care center in Chandigarh, India, during a 4-year period. We evaluated t...

journal_title：Laboratory medicine

authors： Sharma S,Gupta P,Aggarwal R,Malhotra P,Minz RW,Bansal F

更新日期：2019-10-10 00:00:00

abstract：BACKGROUND:Knowledge of transfusion medicine is the key element of better transfusion practices. This deficit observed at the blood bank end on daily basis exposing the patients for redundant risk. We assessed the knowledge of transfusion medicine among post intern doctors. OBJECTIVE:To assess the knowledge of transfu...

journal_title：Laboratory medicine

authors： Kumarage S,Fernando R,Gunasekara L

更新日期：2017-02-01 00:00:00

abstract：PATIENT:78-year-old African-American man. PAST MEDICAL HISTORY:Chronic lymphocytic leukemia first diagnosed in 2003, with a subsequent relapse in 2006 and another in 2010. HISTORY OF PRESENT ILLNESS:In late 2011, the patient was admitted to the hospital for cholelithiasis, at which time his treating physician inciden...

journal_title：Laboratory medicine

authors： Sartori A,Staley B,Skipper A

更新日期：2014-07-01 00:00:00

abstract：Objective:To compare a manual squamous cell carcinoma antigen (SCCA) assay and an automated SCCA assay in a clinical setting. Methods:We included, in this study, a total of 158 specimens that had been tested using the manual SCCA assay. The CanAg SCC EIA assay and the Elecsys SCC were compared for their clinical setti...

journal_title：Laboratory medicine

authors： Lee S,Kim J,Uh Y,Kim HS,Lee JH

更新日期：2018-07-05 00:00:00

abstract：Objective:To assess the effects of depression and anxiety on serum cytokine levels in patients with chronic hepatitis B (CHB) infection. Methods:In this cross-sectional study, 60 healthy control individuals and 60 patients with CHB participated after filling out standard questionnaires. We examined their serum interle...

journal_title：Laboratory medicine

authors： Bahramabadi R,Fathollahi MS,Hashemi SM,Arababadi AS,Arababadi MS,Yousefi-Daredor H,Bidaki R,Khaleghinia M,Bakhshi MH,Yousefpoor Y,Torbaghan YE,Arababadi MK

更新日期：2017-12-22 00:00:00

abstract：:Antinuclear antibodies (ANAs) are autoantibodies that attack self-proteins within cell nucleus structures; their presence in serum may indicate an autoimmune disease. Also, positive ANA test results have been obtained in chronic infectious diseases, cancers, medication-related adverse events, and even healthy individu...

journal_title：Laboratory medicine

authors： Sur LM,Floca E,Sur DG,Colceriu MC,Samasca G,Sur G

更新日期：2018-07-05 00:00:00

abstract：OBJECTIVE:To determine whether K2-ethylenediaminetetraacetic acid (EDTA) and K3-EDTA Greiner tubes could be used interchangeably for glycosylated hemoglobin, type A1C (HbA1c) measurement via the Abbott Laboratories ARCHITECT chemiluminescent microparticle HbA1c assay on the ARCHITECT i2000SR immunoanalyzer at our unive...

journal_title：Laboratory medicine

authors： Vrtaric A,Filipi P,Hemar M,Nikolac N,Simundic AM

更新日期：2016-02-01 00:00:00

abstract：Background:Interest in vitamin D has increased during the past 2 decades, with a corresponding increase in laboratory testing of 25-hydroxyvitamin D [25(OH)D]. The vast majority of specimens tested display normal or deficient levels of 25(OH)D; concentrations rarely fall in the potentially toxic range. Methods:We perf...

journal_title：Laboratory medicine

authors： Lee JP,Tansey M,Jetton JG,Krasowski MD

更新日期：2018-03-21 00:00:00

abstract：:Cell-derived microparticles (MPs) are small fragments released from various cells when they are activated or undergo apoptosis. In the field of transfusion medicine, a number of studies have documented increased levels of MPs in blood products, which have been associated with multiple factors, including donor variabil...

journal_title：Laboratory medicine

authors： Noulsri E

更新日期：2020-09-01 00:00:00

abstract：:Maintaining an in-compliance clinical laboratory takes continuous awareness and review of standards, regulations, and best practices. A strong quality assurance program and well informed leaders who maintain professional networks can aid in this necessary task. This article will discuss a process that laboratories can...

journal_title：Laboratory medicine

authors： Byrne KM,Levy KY,Reese EM

更新日期：2016-05-01 00:00:00

abstract：:Tacrolimus (Tac) is an immunosuppressive drug that is used in preventing organ and tissue rejection in patients after transplantation. Tac administration requires frequent and diligent monitoring by physicians to ensure proper dosage and to limit the potential for harmful adverse effects, which can include renal damag...

journal_title：Laboratory medicine

authors： Kalt DA

更新日期：2017-11-08 00:00:00

abstract：:Storage pool deficiency (SPD) is a group of rare platelet disorders that result from deficiencies in α-granules, δ-granules, or both. One type of α-SPD is gray platelet syndrome (GPS), caused by mutations in the neurobeachin-like 2 (NBEAL2) gene that results in a bleeding diathesis, thrombocytopenia, splenomegaly, and...

journal_title：Laboratory medicine

authors： Riley R,Khan A,Pai S,Warmke L,Winkler M,Gunning W

更新日期：2019-10-10 00:00:00

abstract：OBJECTIVE:Establish whether hemolysis in samples collected from intravenous lines is influenced by catheterization site. METHODS:Blood was collected from all patients (67 total) admitted to the emergency department the same morning, through a 20-gauge catheter placed in a vein of the upper limb directly into an evacua...

journal_title：Laboratory medicine

authors： Lippi G,Avanzini P,Aloe R,Cervellin G

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To identify the osteoprotegerin (OPG) correlates with antiphospholipid syndrome (APS) parameters. METHODS:Our cohort included 40 patients with primary APS disease associated with systemic lupus erythematosus (SLE) (mean age, 43.7 years; 87% female). Data on cardiovascular risk factors and specific clinical e...

journal_title：Laboratory medicine

authors： Caraiola S,Dima A,Jurcut C,Jurcut R,Baicus C,Baicus A

更新日期：2020-03-10 00:00:00

abstract：OBJECTIVE:Inflammation of the small intestine may occur in type 2 diabetes. This study aimed to investigate whether ATP-binding cassette transporter A1 (ABCA1) and G1 (ABCG1) were altered in chronic inflammation of the small intestine of type 2 diabetic rats. METHODS:Thirty-two male Sprague-Dawley rats were used. Eigh...

journal_title：Laboratory medicine

authors： Lou J,Zhou H,Li C,Hu L,Lu X,Li J,Yao H,Li W,Zhang X,Xu M

更新日期：2014-01-01 00:00:00

abstract：:Laboratory professionals, consultants, and treating physicians may encounter discrepancies in serological testing results for numerous reasons; identifying the reason(s) for the presence of an unexpected antibody or antigen can be challenging. A question-based approach can be useful in identifying the underlying cause...

journal_title：Laboratory medicine

authors： Yudin J,Heddle NM

更新日期：2014-07-01 00:00:00

abstract：:The three major causes of anemia in neonates are blood loss, decreased red blood cell production, and increased degradation of erythrocytes. Establishing the cause of anemia in a neonate born prematurely can be challenging. Clinically, fetomaternal hemorrhage (FMH) can be difficult to diagnose-the condition often pres...

journal_title：Laboratory medicine

authors： den Besten G,van der Weide K,Schuerman FABA,Michael Cotten C,Rondeel JMM

更新日期：2018-07-05 00:00:00

abstract：Background:Thromboelastography (TEG) has become the standard of care in liver-transplant surgery to identify real-time abnormalities in the coagulation cascade. To our knowledge, no studies have been performed to measure the intrasubject reproducibility of TEG parameters in cirrhotic patients. Objective:To perform a v...

journal_title：Laboratory medicine

authors： George G,Manatasahit W,Balasubramanian M,Navarro V

更新日期：2018-07-05 00:00:00

abstract：Objective:To determine the effect of presence of high concentrations of nicotinamide adenine dinucleotide (NADH)- and nicotinamide adenine dinucleotide phosphate (NADPH)-consuming enzymes on the accuracy of glutamate dehydrogenase (GLDH) assay for ammonia. Methods:We measured ammonia concentrations using GLDH and NADH...

journal_title：Laboratory medicine

authors： Vodenicarovova M,Skalska H,Holecek M

更新日期：2017-11-08 00:00:00

abstract：:Hormographiella is a rare fungal pathogen in humans; however, case reports have described disseminated infection in immunocompromised hosts. This pathogen has been described to yield poor prognosis in patients who harbor it. Herein, we present a case report of autopsy-proven disseminated Hormographiella aspergillata i...

journal_title：Laboratory medicine

authors： Chauhan A,Gruenberg J,Arbefeville S,Mettler T,Brent CH,Ferrieri P

更新日期：2019-10-10 00:00:00

abstract：:Health systems face intense pressure to decrease costs and improve services as the health care delivery system in the United States undergoes tremendous change due to health care reform. As health systems grow, like any business, they are forced to explore standardization to realize and maintain efficient practices. C...

journal_title：Laboratory medicine

authors： Cook J

更新日期：2017-08-01 00:00:00

abstract：:Primary amoebic meningoencephalitis (PAM) is a rare and almost always fatal disease that is caused by Naegleria fowleri, a freshwater thermophilic amoeba. Our case involves an adolescent female who presented with fever of unknown origin. A lumbar puncture was performed, and the Wright-Giemsa and Gram stained cerebrosp...

journal_title：Laboratory medicine

authors： Dunn AL,Reed T,Stewart C,Levy RA

更新日期：2016-05-01 00:00:00

abstract：Background:The misuse of statistical methods in diagnostic accuracy studies has been criticized in many publications. Objective:To assess the use and misuse of statistical methods in medical journal articles. Methods:We reviewed 141 original articles from 6 cytopathology journals published in 2014. Results:In total,...

journal_title：Laboratory medicine

authors： Bahar B,Pambuccian SE,Barkan GA,Akdas Y

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To establish a new indicator derived from reticulocyte hemoglobin (Ret-He) content and red blood cell (RBC) indices for screening for iron deficiency anemia (IDA) in an area in whch thalassemia is prevalent. METHODS:Blood specimens from 304 women aged between 18 and 30 years residing in northeast Thailand we...

journal_title：Laboratory medicine

authors： Jamnok J,Sanchaisuriya K,Chaitriphop C,Sanchaisuriya P,Fucharoen G,Fucharoen S

更新日期：2020-09-01 00:00:00