Blood collection from intravenous lines: is one drawing site better than others?

abstract：:Extremely low hemoglobin A1c (HbA1c) results below reference range are rare, and the causes and clinical implications associated with low HbA1c results are not well understood among clinical laboratorians. A case of extremely low HbA1c results was reported, in which liver cirrhosis, subacute hemorrhage and recent tran...

journal_title：Laboratory medicine

authors： Wang P

更新日期：2017-02-01 00:00:00

abstract：Background:Early access for routine testing with the Alinity c clinical chemistry system (Abbot Laboratories) presented the opportunity to characterize the analytical performance of multiple analytes across clinical laboratories in Europe. Methods:A total of 8 laboratories from 7 European countries evaluated 10 high-v...

journal_title：Laboratory medicine

authors： Krintus M,Fernandez JA,Chesters C,Colla R,Ford C,Frattolillo D,Köller U,Mairesse J,Jimenez DM,Motol J,Padmore K,Sharrod-Cole H,Sypniewska G

更新日期：2019-01-01 00:00:00

abstract：:We report a case of a false-positive HIV result in an apparently healthy pregnant woman. Since no prenatal HIV testing had been performed, we screened for HIV reactivity utilizing the Architect HIV-Ag/Ab Combo assay. Results obtained were inconsistent in that they were repeatedly HIV reactive on a single serum sample ...

journal_title：Laboratory medicine

authors： Akl P,Blick KE

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Research in several professional fields has demonstrated that delays (time lapse) in taking certification examinations may result in poorer performance by examinees. Thirteen states and/or territories require licensure for laboratory personnel. A core component of licensure is passing a certification exam. A...

journal_title：Laboratory medicine

authors： ASCP Board of Certification Research and Development Committee.,Brown KA,Fenn JP,Freeman VS,Fisher PB,Genzen JR,Goodyear N,Houston ML,O'Brien ME,Tanabe PA

更新日期：2015-07-01 00:00:00

abstract：:Rhizobium radiobacter is an opportunistic, usually saprophytic, gram-negative bacillus found in agricultural soil. Isolation from blood has been reported most often in hospitalized patients harboring malignant neoplasms or human immunodeficiency virus (HIV) associated immunosuppression, who have catheter or medical de...

journal_title：Laboratory medicine

authors： Sawhney S,Naab T,Oneal P

更新日期：2016-08-01 00:00:00

abstract：:Cording is a phenomenon in which acid fast bacilli grow in parallel and was previously used as a means of presumptive microscopic identification of Mycobacterium tuberculosis (TB). However, this process has been shown in multiple other nontuberculous mycobacterial (NTM) species. Here we present the case of an immunoco...

journal_title：Laboratory medicine

authors： Olson G,McNulty MC,Mullane K,Beavis KG,Tesic V

更新日期：2020-09-21 00:00:00

abstract：Background:Thromboelastography (TEG) has become the standard of care in liver-transplant surgery to identify real-time abnormalities in the coagulation cascade. To our knowledge, no studies have been performed to measure the intrasubject reproducibility of TEG parameters in cirrhotic patients. Objective:To perform a v...

journal_title：Laboratory medicine

authors： George G,Manatasahit W,Balasubramanian M,Navarro V

更新日期：2018-07-05 00:00:00

abstract：OBJECTIVE:To investigate the effect of temperature and protease inhibitor on adrenocorticotrophin (ACTH) stability. METHODS:We collected blood specimens from 10 donors into K3 EDTA (ethylenediaminetetraacetic acid) and K3 EDTA + aprotinin tubes. Plasma specimens were held at room temperature and at 2 °C to 8[Formula: ...

journal_title：Laboratory medicine

authors： Turkon H,Toprak B,Yalcin H,Colak A,Ozturk N

更新日期：2016-11-01 00:00:00

abstract：:Maintaining an in-compliance clinical laboratory takes continuous awareness and review of standards, regulations, and best practices. A strong quality assurance program and well informed leaders who maintain professional networks can aid in this necessary task. This article will discuss a process that laboratories can...

journal_title：Laboratory medicine

authors： Byrne KM,Levy KY,Reese EM

更新日期：2016-05-01 00:00:00

abstract：:The main clinical distinction between post-transfusion purpura (PTP) and idiopathic thrombocytopenic purpura (ITP) is the sudden development of severe thrombocytopenia in the days after transfusion. Herein, we report the case of a 53-year-old Caucasian woman who developed multiple myeloma (MM) after peripheral blood-s...

journal_title：Laboratory medicine

authors： Milito C,Masel D,Henrichs K,Schmidt AE,Kirkley S,Aljitawi O,Becker M,Blumberg N,Refaai MA

更新日期：2019-10-10 00:00:00

abstract：BACKGROUND:Multirules are often employed to monitor quality control (QC). The performance of multirules is usually determined by simulation and is difficult to predict. Previous studies have not provided computer code that would enable one to experiment with multirules. It would be helpful for analysts to have computer...

journal_title：Laboratory medicine

authors： Walker BS,Pearson LN,Schmidt RL

更新日期：2020-01-02 00:00:00

abstract：:Waldenström macroglobulinemia (WM) is a form of lymphoplasmacytic lymphoma that can cause hyperviscosity syndrome due to unchecked monoclonal antibody production. Some patients are also found to have associated cryoglobulinemia, which can cause systemic complications including vasculitis, renal disease, and pulmonary ...

journal_title：Laboratory medicine

authors： Beech C,Kumar D,Hendrickson J,Perincheri S,Tormey C,Bahar B

更新日期：2019-07-16 00:00:00

abstract：OBJECTIVE:To determine whether K2-ethylenediaminetetraacetic acid (EDTA) and K3-EDTA Greiner tubes could be used interchangeably for glycosylated hemoglobin, type A1C (HbA1c) measurement via the Abbott Laboratories ARCHITECT chemiluminescent microparticle HbA1c assay on the ARCHITECT i2000SR immunoanalyzer at our unive...

journal_title：Laboratory medicine

authors： Vrtaric A,Filipi P,Hemar M,Nikolac N,Simundic AM

更新日期：2016-02-01 00:00:00

abstract：Background:Anti-phospholipase A2 receptor (anti-PLA2R) is a promising biomarker for diagnosis, activity evaluation, therapy monitoring, and prognostic estimation of primary membranous neuropathy (pMN). Difference in methodology may be one cause of the discrepancy in anti-PLA2R-positive percentages in reported studies. ...

journal_title：Laboratory medicine

authors： Li W,Guo Y,Zhang Z,Zhang F,Liu X,Ji X,Liu L,Wang H

更新日期：2018-10-11 00:00:00

abstract：:Rivaroxaban (Xarelto; Johnson & Johnson Services, Inc) is a direct oral anticoagulant (DOAC) that works by directly inhibiting the active site of factor Xa (FXa). Rivaroxaban is metabolized and cleared via the kidney and liver. The results of various studies have shown that patients with severe renal impairment should...

journal_title：Laboratory medicine

authors： Milito C,McRae H,Victor A,Refaai MA,Schmidt AE

更新日期：2020-03-10 00:00:00

abstract：:In the past few years, interest has increased in cell-derived microparticles (MPs), which are defined by their size of from 0.1 to 1 μm, and can be derived from various cell types, including endothelial cells, leukocytes, red blood cells (RBCs), and platelets. These MPs carry negatively charged phosphatidylserine (PS)...

journal_title：Laboratory medicine

authors： Noulsri E

更新日期：2020-08-20 00:00:00

abstract：OBJECTIVE:To determine and optimize the sensitivity of the CellaVision DM96 automated image-analysis system in detecting platelet (PLT) clumps on blood smears and to assess the reliability of the traditional laboratory practice of examining only the feather edge of the smear for PLT clumps. METHODS:We processed 102 bl...

journal_title：Laboratory medicine

authors： Gulati G,Uppal G,Florea AD,Gong J

更新日期：2014-10-01 00:00:00

abstract：Background:When unpredicted surgical blood loss occurs, it is essential that blood arrive from the blood bank in a timely manner. Objective:To evaluate the turnaround time (TAT) for red blood cells (RBCs) from the blood bank to the operating suite. Cases with delayed TATs were further analyzed to determine potential c...

journal_title：Laboratory medicine

authors： Lee AJ,Kim SG

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To explore novel biomarkers for patients with pancreatic ductal adenocarcinoma (PDAC), from the perspective of tumor hypoxia. METHODS:We screened 29 differentially expressed and hypoxia-upregulated genes from the Oncomine database. A total of 12 secretory proteins that interact with hypoxia-inducible factor ...

journal_title：Laboratory medicine

authors： Yang L,Cui R,Li Y,Liang K,Ni M,Gu Y

更新日期：2020-07-08 00:00:00

abstract：:The three major causes of anemia in neonates are blood loss, decreased red blood cell production, and increased degradation of erythrocytes. Establishing the cause of anemia in a neonate born prematurely can be challenging. Clinically, fetomaternal hemorrhage (FMH) can be difficult to diagnose-the condition often pres...

journal_title：Laboratory medicine

authors： den Besten G,van der Weide K,Schuerman FABA,Michael Cotten C,Rondeel JMM

更新日期：2018-07-05 00:00:00

abstract：:Non-specific antibodies or antibodies of undetermined significance (AUS) often pose problems for a blood bank technologist and physician. It is well known that antibodies can weaken and evanesce over time, thus eluding detection by routine blood bank techniques. Special enhancement techniques exist (eg, ficin treatmen...

journal_title：Laboratory medicine

authors： Hill BC,Hanna CA,Adamski J,Pham HP,Marques MB,Williams LA 3rd

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To investigate the expression level and clinical significance of microRNA-155 (miR-155) in bladder cancer. METHODS:We collected 102 pairs of tissue specimens from patients with primary bladder cancer and adjacent normal bladder specimens between March 2008 and May 2013. Quantitative real-time polymerase chai...

journal_title：Laboratory medicine

authors： Wang H,Men CP

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Single-vial fecal immunochemical testing (FIT) is an accepted method of colorectal cancer (CRC) screening. The available 3-vial FIT data set allows for comparison of colonoscopy results using various screening methods. OBJECTIVE:To determine the optimal number of vials for a strong FIT-screening program by ...

journal_title：Laboratory medicine

authors： Hancock JA,Palmer GA

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Currently, more than 45 mathematical formulas based on simple red blood cell (RBC) parameters have been proposed for differentiating between iron deficiency and thalassemia in microcytic anemia, of which 20 are relatively new and have not been thoroughly independently verified. The study goal was to verify t...

journal_title：Laboratory medicine

authors： Hoffmann JJML,Urrechaga E

更新日期：2020-11-02 00:00:00

abstract：BACKGROUND:Knowledge of transfusion medicine is the key element of better transfusion practices. This deficit observed at the blood bank end on daily basis exposing the patients for redundant risk. We assessed the knowledge of transfusion medicine among post intern doctors. OBJECTIVE:To assess the knowledge of transfu...

journal_title：Laboratory medicine

authors： Kumarage S,Fernando R,Gunasekara L

更新日期：2017-02-01 00:00:00

abstract：Background:The misuse of statistical methods in diagnostic accuracy studies has been criticized in many publications. Objective:To assess the use and misuse of statistical methods in medical journal articles. Methods:We reviewed 141 original articles from 6 cytopathology journals published in 2014. Results:In total,...

journal_title：Laboratory medicine

authors： Bahar B,Pambuccian SE,Barkan GA,Akdas Y

更新日期：2019-01-01 00:00:00

abstract：:Caspases play a vital role during apoptosis. In addition to apoptosis, caspases play a role in cytokine gene induction and work to inhibit apoptosis. In order for individuals to thrive with useful tissue growth, the rate of cell growth and division must surpass the rate of cell division. It is well established that ex...

journal_title：Laboratory medicine

authors： Gupta A,Yo J,Huang G,Soong L,Dong J

更新日期：2018-03-21 00:00:00

abstract：BACKGROUND:The production of 2 monoclonal proteins characterizes biclonal gammopathic manifestations (BGMs). The available medical literature from India is chiefly restricted to case reports. OBJECTIVE:To study the incidence of BGMs in a tertiary care center in Chandigarh, India, during a 4-year period. We evaluated t...

journal_title：Laboratory medicine

authors： Sharma S,Gupta P,Aggarwal R,Malhotra P,Minz RW,Bansal F

更新日期：2019-10-10 00:00:00

abstract：OBJECTIVE:Platelet counts generated by automated analyzers on blood specimens that contain platelet clumps are often inaccurate and require verification by blood-smear review. In this study, we assessed the reliability of the Sysmex XE-5000 instrument to detect platelet clumps. METHOD:We reviewed automated complete bl...

journal_title：Laboratory medicine

authors： Hawkins J,Gulati G,Uppal G,Gong J

更新日期：2016-08-01 00:00:00

abstract：PATIENT:78-year-old African-American man. PAST MEDICAL HISTORY:Chronic lymphocytic leukemia first diagnosed in 2003, with a subsequent relapse in 2006 and another in 2010. HISTORY OF PRESENT ILLNESS:In late 2011, the patient was admitted to the hospital for cholelithiasis, at which time his treating physician inciden...

journal_title：Laboratory medicine

authors： Sartori A,Staley B,Skipper A

更新日期：2014-07-01 00:00:00