Abstract:
Background:When unpredicted surgical blood loss occurs, it is essential that blood arrive from the blood bank in a timely manner. Objective:To evaluate the turnaround time (TAT) for red blood cells (RBCs) from the blood bank to the operating suite. Cases with delayed TATs were further analyzed to determine potential causes for the delays. Methods:During a 6-month period, intraoperative RBC requests were included among the blood component request lists at a single tertiary care hospital. Results:A total of 387 RBC-product requests were received from the operating room, of which 220 (56.8%) cases were intraoperative requests. The overall mean (SD) TAT was 19.4 (9.8) minutes. Mean (SD) preparation-to-issuance time (14.9 [7.8] minutes) contributed more to the overall TAT than did mean (SD) request-to-preparation time (4.5 [7.4] minutes). The 31 cases (14.1%) exceeded the internally mandated TAT threshold (> 30 minutes). Prolonged compatibility testing and delayed courier arrival contributed to TAT delay. Conclusions:TAT standards for issuing RBCs from the blood bank to the operating suite should be established and carefully monitored for quality improvement of transfusion services.
journal_name
Lab Medjournal_title
Laboratory medicineauthors
Lee AJ,Kim SGdoi
10.1093/labmed/lmx016subject
Has Abstractpub_date
2017-08-01 00:00:00pages
277-281issue
3eissn
0007-5027issn
1943-7730pii
3902925journal_volume
48pub_type
杂志文章abstract::The COVID-19 pandemic has led to a major setback in both the health and economic sectors across the globe. The scale of the problem is enormous because we still do not have any specific anti-SARS-CoV-2 antiviral agent or vaccine. The human immune system has never been exposed to this novel virus, so the viral interact...
journal_title:Laboratory medicine
pub_type: 杂志文章,评审
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmy016
更新日期:2018-10-11 00:00:00
abstract::As new killer-cell immunoglobulin-like receptor (KIR) alleles are discovered, a challenge in KIR typing is maintaining sensitivity and specificity. A single nucleotide polymorphism assay can be used to type functional KIR2DL1 alleles. We improved recently on the earlier method by using a higher-specificity assay. The ...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1309/LMMN1K6SBRJCGD9J
更新日期:2015-07-01 00:00:00
abstract::In the past few years, interest has increased in cell-derived microparticles (MPs), which are defined by their size of from 0.1 to 1 μm, and can be derived from various cell types, including endothelial cells, leukocytes, red blood cells (RBCs), and platelets. These MPs carry negatively charged phosphatidylserine (PS)...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmaa043
更新日期:2020-08-20 00:00:00
abstract::Hormographiella is a rare fungal pathogen in humans; however, case reports have described disseminated infection in immunocompromised hosts. This pathogen has been described to yield poor prognosis in patients who harbor it. Herein, we present a case report of autopsy-proven disseminated Hormographiella aspergillata i...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz018
更新日期:2019-10-10 00:00:00
abstract:OBJECTIVE:To evaluate broad-range 16S ribosomal DNA (rDNA) polymerase chain reaction (PCR) as a rapid screening tool to detect bacterial contamination of stem-cell products. METHODS:We performed the evaluation using whole blood spiked with serially diluted bacterial-type strains. Detection sensitivity was defined as t...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1309/LMKT4P9FFI2BBSIU
更新日期:2015-01-01 00:00:00
abstract::Herein, we present a case of extensive lymph node involvement by disseminated Cryptococcus infection developing in the immediate period after liver transplantation and initiation of immunosuppressive therapy. The patient, a 56 year old ethnicity unknown man, received a liver transplant for acute decompensated liver. B...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmy021
更新日期:2018-07-05 00:00:00
abstract:OBJECTIVE:To evaluate and compare the performances of the automated urinalysis devices UX-2000 and Cobas 6500. METHOD:A total of 258 urine specimens were collected from the routine specimen workload. We analyzed all specimens on both automated instruments and recorded the turnaround time from each method. Physical, ch...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmw002
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:Tyrosine kinase inhibitors (TKIs) are considered standard first-line treatment in patients with chronic myeloid leukemia. Because ABL kinase domain mutations are the most common causes of treatment resistance, their prevalence and assessment during treatment may predict subsequent response to therapy. METHOD...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmaa052
更新日期:2020-08-21 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章,评审
doi:10.1093/labmed/lmy036
更新日期:2019-01-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmw062
更新日期:2017-02-01 00:00:00
abstract::Storage pool deficiency (SPD) is a group of rare platelet disorders that result from deficiencies in α-granules, δ-granules, or both. One type of α-SPD is gray platelet syndrome (GPS), caused by mutations in the neurobeachin-like 2 (NBEAL2) gene that results in a bleeding diathesis, thrombocytopenia, splenomegaly, and...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz013
更新日期:2019-10-10 00:00:00
abstract:Objective:To assess the effects of depression and anxiety on serum cytokine levels in patients with chronic hepatitis B (CHB) infection. Methods:In this cross-sectional study, 60 healthy control individuals and 60 patients with CHB participated after filling out standard questionnaires. We examined their serum interle...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmx064
更新日期:2017-12-22 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmw044
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To investigate the expression level and clinical significance of microRNA-155 (miR-155) in bladder cancer. METHODS:We collected 102 pairs of tissue specimens from patients with primary bladder cancer and adjacent normal bladder specimens between March 2008 and May 2013. Quantitative real-time polymerase chai...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1309/LMWR9CEA2K2XVSOX
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:To explore novel biomarkers for patients with pancreatic ductal adenocarcinoma (PDAC), from the perspective of tumor hypoxia. METHODS:We screened 29 differentially expressed and hypoxia-upregulated genes from the Oncomine database. A total of 12 secretory proteins that interact with hypoxia-inducible factor ...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz063
更新日期:2020-07-08 00:00:00
abstract:OBJECTIVE:To establish a new indicator derived from reticulocyte hemoglobin (Ret-He) content and red blood cell (RBC) indices for screening for iron deficiency anemia (IDA) in an area in whch thalassemia is prevalent. METHODS:Blood specimens from 304 women aged between 18 and 30 years residing in northeast Thailand we...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz099
更新日期:2020-09-01 00:00:00
abstract::Hereditary hemochromatosis (HH) is an autosomal recessive disorder of iron metabolism characterized by increased iron absorption and tissue deposition. Three loss-of-function mutations in the hemochromatosis gene (HFE), namely, C282Y (c.845G>A), H63D (c.187C>G), and S65C (c.193A>T), account for the vast majority of HH...
journal_title:Laboratory medicine
pub_type: 杂志文章,评审
doi:10.1093/labmed/lmy065
更新日期:2019-04-08 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmy086
更新日期:2019-07-16 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1309/LMLWQDB2Q6LS7VQG
更新日期:2014-07-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz092
更新日期:2020-05-06 00:00:00
abstract::Antinuclear antibodies (ANAs) are autoantibodies that attack self-proteins within cell nucleus structures; their presence in serum may indicate an autoimmune disease. Also, positive ANA test results have been obtained in chronic infectious diseases, cancers, medication-related adverse events, and even healthy individu...
journal_title:Laboratory medicine
pub_type: 杂志文章,评审
doi:10.1093/labmed/lmy024
更新日期:2018-07-05 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1309/lms0wn7k7ukzcpmi
更新日期:2014-01-01 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章,多中心研究
doi:10.1093/labmed/lmy053
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Single-vial fecal immunochemical testing (FIT) is an accepted method of colorectal cancer (CRC) screening. The available 3-vial FIT data set allows for comparison of colonoscopy results using various screening methods. OBJECTIVE:To determine the optimal number of vials for a strong FIT-screening program by ...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmy075
更新日期:2019-07-16 00:00:00
abstract::Cording is a phenomenon in which acid fast bacilli grow in parallel and was previously used as a means of presumptive microscopic identification of Mycobacterium tuberculosis (TB). However, this process has been shown in multiple other nontuberculous mycobacterial (NTM) species. Here we present the case of an immunoco...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmaa082
更新日期:2020-09-21 00:00:00
abstract:BACKGROUND:Multirules are often employed to monitor quality control (QC). The performance of multirules is usually determined by simulation and is difficult to predict. Previous studies have not provided computer code that would enable one to experiment with multirules. It would be helpful for analysts to have computer...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz038
更新日期:2020-01-02 00:00:00
abstract:BACKGROUND:Currently, more than 45 mathematical formulas based on simple red blood cell (RBC) parameters have been proposed for differentiating between iron deficiency and thalassemia in microcytic anemia, of which 20 are relatively new and have not been thoroughly independently verified. The study goal was to verify t...
journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmaa030
更新日期:2020-11-02 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmaa069
更新日期:2020-10-03 00:00:00
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journal_title:Laboratory medicine
pub_type: 杂志文章
doi:10.1093/labmed/lmz044
更新日期:2020-03-10 00:00:00