Mesenchymal Stem Cells in COVID-19: A Journey from Bench to Bedside.

abstract：OBJECTIVE:To evaluate the association of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in urine with chronic kidney disease (CKD). METHODS:Case-control study including 50 patients with CKD and 20 healthy volunteers. RESULTS:SAM level and SAM/SAH ratio in urine were significantly lower in patients than i...

journal_title：Laboratory medicine

authors： Kruglova MP,Grachev SV,Bulgakova PO,Ivanov AV,Virus ED,Nikiforova KA,Fedoseev AN,Savina GD,Kubatiev AA

更新日期：2020-01-02 00:00:00

abstract：Background:Anti-phospholipase A2 receptor (anti-PLA2R) is a promising biomarker for diagnosis, activity evaluation, therapy monitoring, and prognostic estimation of primary membranous neuropathy (pMN). Difference in methodology may be one cause of the discrepancy in anti-PLA2R-positive percentages in reported studies. ...

journal_title：Laboratory medicine

authors： Li W,Guo Y,Zhang Z,Zhang F,Liu X,Ji X,Liu L,Wang H

更新日期：2018-10-11 00:00:00

abstract：Background:Early access for routine testing with the Alinity c clinical chemistry system (Abbot Laboratories) presented the opportunity to characterize the analytical performance of multiple analytes across clinical laboratories in Europe. Methods:A total of 8 laboratories from 7 European countries evaluated 10 high-v...

journal_title：Laboratory medicine

authors： Krintus M,Fernandez JA,Chesters C,Colla R,Ford C,Frattolillo D,Köller U,Mairesse J,Jimenez DM,Motol J,Padmore K,Sharrod-Cole H,Sypniewska G

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To test a hybrid polyethylene glycol (PEG)/gel method, specifically to attempt to increase reaction strength of accidentally overdiluted anti-Cob and broadly for proof of concept. METHODS:Methods were divided into 2 basic steps: sensitization and antiglobulin (AHG) testing. Sensitization was performed with P...

journal_title：Laboratory medicine

authors： Delk AA,Gammon RR

更新日期：2020-03-10 00:00:00

abstract：Background:Thromboelastography (TEG) has become the standard of care in liver-transplant surgery to identify real-time abnormalities in the coagulation cascade. To our knowledge, no studies have been performed to measure the intrasubject reproducibility of TEG parameters in cirrhotic patients. Objective:To perform a v...

journal_title：Laboratory medicine

authors： George G,Manatasahit W,Balasubramanian M,Navarro V

更新日期：2018-07-05 00:00:00

abstract：OBJECTIVE:To establish a new indicator derived from reticulocyte hemoglobin (Ret-He) content and red blood cell (RBC) indices for screening for iron deficiency anemia (IDA) in an area in whch thalassemia is prevalent. METHODS:Blood specimens from 304 women aged between 18 and 30 years residing in northeast Thailand we...

journal_title：Laboratory medicine

authors： Jamnok J,Sanchaisuriya K,Chaitriphop C,Sanchaisuriya P,Fucharoen G,Fucharoen S

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To explore novel biomarkers for patients with pancreatic ductal adenocarcinoma (PDAC), from the perspective of tumor hypoxia. METHODS:We screened 29 differentially expressed and hypoxia-upregulated genes from the Oncomine database. A total of 12 secretory proteins that interact with hypoxia-inducible factor ...

journal_title：Laboratory medicine

authors： Yang L,Cui R,Li Y,Liang K,Ni M,Gu Y

更新日期：2020-07-08 00:00:00

abstract：OBJECTIVE:Establish whether hemolysis in samples collected from intravenous lines is influenced by catheterization site. METHODS:Blood was collected from all patients (67 total) admitted to the emergency department the same morning, through a 20-gauge catheter placed in a vein of the upper limb directly into an evacua...

journal_title：Laboratory medicine

authors： Lippi G,Avanzini P,Aloe R,Cervellin G

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Auramine-phenol stain was compared with Kinyoun's acid-fast stain to detect coccidia parasites in fecal samples from immunocompromised patients. The comparison was based on the number of detected cases, sensitivity, specificity, time required for the procedure, ease of use, interpretation, and cost. METHODS:...

journal_title：Laboratory medicine

authors： Abou El-Naga IF,Gaafar MR

更新日期：2014-01-01 00:00:00

abstract：:As new killer-cell immunoglobulin-like receptor (KIR) alleles are discovered, a challenge in KIR typing is maintaining sensitivity and specificity. A single nucleotide polymorphism assay can be used to type functional KIR2DL1 alleles. We improved recently on the earlier method by using a higher-specificity assay. The ...

journal_title：Laboratory medicine

authors： Bari R,Schell S,Tuggle M,Leung W

更新日期：2015-07-01 00:00:00

abstract：PATIENT:78-year-old African-American man. PAST MEDICAL HISTORY:Chronic lymphocytic leukemia first diagnosed in 2003, with a subsequent relapse in 2006 and another in 2010. HISTORY OF PRESENT ILLNESS:In late 2011, the patient was admitted to the hospital for cholelithiasis, at which time his treating physician inciden...

journal_title：Laboratory medicine

authors： Sartori A,Staley B,Skipper A

更新日期：2014-07-01 00:00:00

abstract：Objective:To assess the effects of depression and anxiety on serum cytokine levels in patients with chronic hepatitis B (CHB) infection. Methods:In this cross-sectional study, 60 healthy control individuals and 60 patients with CHB participated after filling out standard questionnaires. We examined their serum interle...

journal_title：Laboratory medicine

authors： Bahramabadi R,Fathollahi MS,Hashemi SM,Arababadi AS,Arababadi MS,Yousefi-Daredor H,Bidaki R,Khaleghinia M,Bakhshi MH,Yousefpoor Y,Torbaghan YE,Arababadi MK

更新日期：2017-12-22 00:00:00

abstract：:Health systems face intense pressure to decrease costs and improve services as the health care delivery system in the United States undergoes tremendous change due to health care reform. As health systems grow, like any business, they are forced to explore standardization to realize and maintain efficient practices. C...

journal_title：Laboratory medicine

authors： Cook J

更新日期：2017-08-01 00:00:00

abstract：:Storage pool deficiency (SPD) is a group of rare platelet disorders that result from deficiencies in α-granules, δ-granules, or both. One type of α-SPD is gray platelet syndrome (GPS), caused by mutations in the neurobeachin-like 2 (NBEAL2) gene that results in a bleeding diathesis, thrombocytopenia, splenomegaly, and...

journal_title：Laboratory medicine

authors： Riley R,Khan A,Pai S,Warmke L,Winkler M,Gunning W

更新日期：2019-10-10 00:00:00

abstract：BACKGROUND:The production of 2 monoclonal proteins characterizes biclonal gammopathic manifestations (BGMs). The available medical literature from India is chiefly restricted to case reports. OBJECTIVE:To study the incidence of BGMs in a tertiary care center in Chandigarh, India, during a 4-year period. We evaluated t...

journal_title：Laboratory medicine

authors： Sharma S,Gupta P,Aggarwal R,Malhotra P,Minz RW,Bansal F

更新日期：2019-10-10 00:00:00

abstract：:Myeloperoxidase (MPO) deficiency, one of the most common inherited phagocyte defects, and may exist as a transient phenomenon in combination with some clinical condition. Hematological analyzer ADVIA 2120i is used to identify the different types of leukocytes based on their size and staining properties, and by mean pe...

journal_title：Laboratory medicine

authors： Roh S,Ham JY,Song KE,Hwang N,Lee NY

更新日期：2020-03-10 00:00:00

abstract：:Antinuclear antibodies (ANAs) are autoantibodies that attack self-proteins within cell nucleus structures; their presence in serum may indicate an autoimmune disease. Also, positive ANA test results have been obtained in chronic infectious diseases, cancers, medication-related adverse events, and even healthy individu...

journal_title：Laboratory medicine

authors： Sur LM,Floca E,Sur DG,Colceriu MC,Samasca G,Sur G

更新日期：2018-07-05 00:00:00

abstract：Background:Interest in vitamin D has increased during the past 2 decades, with a corresponding increase in laboratory testing of 25-hydroxyvitamin D [25(OH)D]. The vast majority of specimens tested display normal or deficient levels of 25(OH)D; concentrations rarely fall in the potentially toxic range. Methods:We perf...

journal_title：Laboratory medicine

authors： Lee JP,Tansey M,Jetton JG,Krasowski MD

更新日期：2018-03-21 00:00:00

abstract：:Waldenström macroglobulinemia (WM) is a form of lymphoplasmacytic lymphoma that can cause hyperviscosity syndrome due to unchecked monoclonal antibody production. Some patients are also found to have associated cryoglobulinemia, which can cause systemic complications including vasculitis, renal disease, and pulmonary ...

journal_title：Laboratory medicine

authors： Beech C,Kumar D,Hendrickson J,Perincheri S,Tormey C,Bahar B

更新日期：2019-07-16 00:00:00

abstract：OBJECTIVE:To determine and optimize the sensitivity of the CellaVision DM96 automated image-analysis system in detecting platelet (PLT) clumps on blood smears and to assess the reliability of the traditional laboratory practice of examining only the feather edge of the smear for PLT clumps. METHODS:We processed 102 bl...

journal_title：Laboratory medicine

authors： Gulati G,Uppal G,Florea AD,Gong J

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To identify the osteoprotegerin (OPG) correlates with antiphospholipid syndrome (APS) parameters. METHODS:Our cohort included 40 patients with primary APS disease associated with systemic lupus erythematosus (SLE) (mean age, 43.7 years; 87% female). Data on cardiovascular risk factors and specific clinical e...

journal_title：Laboratory medicine

authors： Caraiola S,Dima A,Jurcut C,Jurcut R,Baicus C,Baicus A

更新日期：2020-03-10 00:00:00

abstract：Background:When unpredicted surgical blood loss occurs, it is essential that blood arrive from the blood bank in a timely manner. Objective:To evaluate the turnaround time (TAT) for red blood cells (RBCs) from the blood bank to the operating suite. Cases with delayed TATs were further analyzed to determine potential c...

journal_title：Laboratory medicine

authors： Lee AJ,Kim SG

更新日期：2017-08-01 00:00:00

abstract：Background:The misuse of statistical methods in diagnostic accuracy studies has been criticized in many publications. Objective:To assess the use and misuse of statistical methods in medical journal articles. Methods:We reviewed 141 original articles from 6 cytopathology journals published in 2014. Results:In total,...

journal_title：Laboratory medicine

authors： Bahar B,Pambuccian SE,Barkan GA,Akdas Y

更新日期：2019-01-01 00:00:00

abstract：:Hereditary hemochromatosis (HH) is an autosomal recessive disorder of iron metabolism characterized by increased iron absorption and tissue deposition. Three loss-of-function mutations in the hemochromatosis gene (HFE), namely, C282Y (c.845G>A), H63D (c.187C>G), and S65C (c.193A>T), account for the vast majority of HH...

journal_title：Laboratory medicine

authors： Turbiville D,Du X,Yo J,Jana BR,Dong J

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Preparation of the patient for laboratory tests is crucial. Our aim was to investigate the current practice and regional variability of recommendations regarding patient preparation for laboratory testing. METHODS:A call for data was posted by email. Spanish laboratories were invited to fill out and submit ...

journal_title：Laboratory medicine

authors： Salinas M,López-Garrigós M,Flores E,Leiva-Salinas C

更新日期：2020-05-06 00:00:00

abstract：:Caspases play a vital role during apoptosis. In addition to apoptosis, caspases play a role in cytokine gene induction and work to inhibit apoptosis. In order for individuals to thrive with useful tissue growth, the rate of cell growth and division must surpass the rate of cell division. It is well established that ex...

journal_title：Laboratory medicine

authors： Gupta A,Yo J,Huang G,Soong L,Dong J

更新日期：2018-03-21 00:00:00

abstract：OBJECTIVE:Tyrosine kinase inhibitors (TKIs) are considered standard first-line treatment in patients with chronic myeloid leukemia. Because ABL kinase domain mutations are the most common causes of treatment resistance, their prevalence and assessment during treatment may predict subsequent response to therapy. METHOD...

journal_title：Laboratory medicine

authors： Shojaei M,Rezvani H,Azarkeivan A,Poopak B

更新日期：2020-08-21 00:00:00

abstract：:Laboratory professionals, consultants, and treating physicians may encounter discrepancies in serological testing results for numerous reasons; identifying the reason(s) for the presence of an unexpected antibody or antigen can be challenging. A question-based approach can be useful in identifying the underlying cause...

journal_title：Laboratory medicine

authors： Yudin J,Heddle NM

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Single-vial fecal immunochemical testing (FIT) is an accepted method of colorectal cancer (CRC) screening. The available 3-vial FIT data set allows for comparison of colonoscopy results using various screening methods. OBJECTIVE:To determine the optimal number of vials for a strong FIT-screening program by ...

journal_title：Laboratory medicine

authors： Hancock JA,Palmer GA

更新日期：2019-07-16 00:00:00

abstract：OBJECTIVE:Examination of urine sediment is crucial in acute kidney injury (AKI). In such renal injury, tubular epithelial cells, epithelial cell casts, and dysmorphic red cells may provide clues to etiology. The aim of this study was to compare automated urinalysis findings with manual microscopic analysis in AKI. MET...

journal_title：Laboratory medicine

authors： Chandrashekar V,Tarigopula A,Prabhakar V

更新日期：2020-10-03 00:00:00