Cyanine Modification Tuned for Amine Photorelease.

abstract：:Cryptococus gattii is an emergent primary human pathogen that causes meningismus, papilledema, high intracranial pressure and focal involvement of the central nervous system in immunocompetent hosts. Prolonged antifungal therapy is the conventional treatment, but it is highly toxic, selects for resistant strains, cont...

journal_title：Photochemistry and photobiology

authors： Soares BM,Alves OA,Ferreira MV,Amorim JC,Sousa GR,Silveira Lde B,Prates RA,Avila TV,Baltazar Lde M,de Souza Dda G,Santos DA,Modolo LV,Cisalpino PS,Pinotti M

更新日期：2011-03-01 00:00:00

abstract：:The photosolvolysis of several biphenyl methanols (Ph-PhCH[Ph]OH) substituted with hydroxy or methoxy groups on the benzene ring not containing the -CH(Ph)OH moiety has been studied in aqueous solution. This work is a continuation of our studies of photosolvolysis of hydroxy-substituted arylmethanols that generate qui...

journal_title：Photochemistry and photobiology

authors： Xu M,Lukeman M,Wan P

更新日期：2006-01-01 00:00:00

abstract：:We have studied the photophysics and rotational diffusion of hydrophilic solute 7-(N, N'-diethylamino)coumarin-3-carboxylic acid (7-DCCA) in a room temperature ionic liquid methyltrioctylammonium bis(trifluoromethylsulfonyl) imide ([N1888 ][NTf2 ]). Comparison of activation energies of viscous flow and nonradiative de...

journal_title：Photochemistry and photobiology

authors： Chatterjee A,Maity B,Ahmed SA,Seth D

更新日期：2015-09-01 00:00:00

abstract：:Proton magnetic resonance imaging (MRI) and histological methods were used to evaluate photodynamic therapy (PDT)-induced hemorrhagic necrosis in the murine M1 tumor within 72 h of treatment of male DBA/2 mice. The effects of three photosensitizing drugs were investigated: Photofrin (n = 4), Zn (II) phthalocyanine (n ...

journal_title：Photochemistry and photobiology

authors： Winsborrow BG,Grondey H,Savoie H,Fyfe CA,Dolphin D

更新日期：1997-12-01 00:00:00

abstract：:Luciferin-regenerating enzyme (LRE) contributes to in vitro recycling of D-luciferin. In this study, reinvestigation of the luciferase-based LRE assay is reported. Here, using quick change site-directed mutagenesis seven T-LRE (Lampyris turkestanicusLRE) mutants were constructed and the most functional mutant of T-LRE...

journal_title：Photochemistry and photobiology

authors： Hemmati R,Hosseinkhani S,Sajedi RH,Azad T,Tashakor A,Bakhtiari N,Ataei F

更新日期：2015-07-01 00:00:00

abstract：:Photoautotrophic growth of Chlamydomonas reinhardtii was shown to be independent of the presence of atmospheric oxygen. Under constant light and photoautotrophic conditions, C. reinhardtii grew equally well in either air or 367 PPM CO2-in-He. During 12-h light-dark cycles, the cells in air grew substantially faster th...

journal_title：Photochemistry and photobiology

authors： Graves DA,Spradlin GM,Greenbaum E

更新日期：1990-09-01 00:00:00

abstract：:Photoreduction of cytochrome c (Cyt c) has been reinvestigated using femtosecond-to-nanosecond transient absorption and stationary spectroscopy. Femtosecond spectra of oxidized Cyt c, recorded in the probe range 270-1000 nm, demonstrate similar evolution upon 266 or 403 nm excitation: an ultrafast 0.3 ps internal conv...

journal_title：Photochemistry and photobiology

authors： Löwenich D,Kleinermanns K,Karunakaran V,Kovalenko SA

更新日期：2008-01-01 00:00:00

abstract：:From June to September 2005, we carried out experiments to determine the ultraviolet radiation (UVR) -induced photoinhibition of summer phytoplankton assemblages from a coastal site of the South China Sea. Variability in taxonomic composition was determined throughout the summer, with a peak chlorophyll a (chl a appro...

journal_title：Photochemistry and photobiology

authors： Gao K,Li G,Helbling EW,Villafañe VE

更新日期：2007-07-01 00:00:00

abstract：:The Escherichia coli protein YcgF contains a photosensory flavin adenine dinucleotide (FAD)-binding BLUF domain covalently linked to an EAL domain, which is predicted to have cyclic-di-guanosine monophosphate (GMP) phosphodiesterase activity. We have cloned, overexpressed and purified this protein, which we refer to a...

journal_title：Photochemistry and photobiology

authors： Rajagopal S,Key JM,Purcell EB,Boerema DJ,Moffat K

更新日期：2004-11-01 00:00:00

abstract：:The XPA gene-deficient mouse, an animal model of xeroderma pigmentosum (XP), develops enhanced photobiologic reactions including acute inflammation, immunosuppression and skin carcinogenesis, because of the defect in the excision repair of ultraviolet-induced DNA lesions. The results strongly suggest that nuclear DNA ...

journal_title：Photochemistry and photobiology

authors： Horio T,Miyauchi-Hashimoto H,Kuwamoto K,Yamazaki F,Okamoto H

更新日期：2007-01-01 00:00:00

abstract：:We recently reported that variations in cellular phototoxicity among a series of alkynyl-substituted zinc trisulfophthalocyanines (ZnPcS3Cn) correlates with their hydrophobicity, with the most amphiphilic derivatives showing the highest cell uptake and phototoxicity. In this study we address the role of the plasma mem...

journal_title：Photochemistry and photobiology

authors： Cauchon N,Nader M,Bkaily G,van Lier JE,Hunting D

更新日期：2006-11-01 00:00:00

abstract：:The design, synthesis and application of a new fluorescent-labeling reagent for collagen has been developed as a prerequisite for the design of a photoactivated collagen-crosslinking compound for surgical wound closure. The amine groups in collagen are the targets of a rational design for a new fluorophore because nat...

journal_title：Photochemistry and photobiology

authors： Timberlake GT,Reddy GK,Stehno-Bittel L,Weber JF,Amslinger S,Givens RS

更新日期：2002-11-01 00:00:00

abstract：:Assignment of the fluorescence spectrum of firefly luciferin in aqueous solutions was achieved by utilizing not only emission energies but also theoretical absorption spectra and relative concentrations as estimated by pKa values. Calculated Gibbs free energies were utilized to estimate pKa values. These pKa values we...

journal_title：Photochemistry and photobiology

authors： Hiyama M,Akiyama H,Yamada K,Koga N

更新日期：2014-01-01 00:00:00

abstract：:The recently discovered photo-activated adenylyl cyclase (mPAC from Microcoleus chthonoplastes) is the first PAC that owes a light-, oxygen- and voltage-sensitive (LOV) domain for blue-light sensing. The photoreaction of the mPAC receptor was studied by time-resolved UV/vis and light-induced Fourier transform infrared...

journal_title：Photochemistry and photobiology

authors： Kerruth S,Langner P,Raffelberg S,Gärtner W,Heberle J

更新日期：2017-05-01 00:00:00

abstract：:Comparative study of 13,15-[N-(2-hydroxyethyl)]cycloimide chlorin p6 (2), 13,15-(N-acetoxy)cycloimide chlorin p6 (3), 13,15-(N-hydroxy)cycloimide chlorin p6 methyl ester (4) and 13,15-(N-methoxy)cycloimide chlorin p6 methyl ester (5) together with the previously investigated 13,15-[N-(3-hydroxypropyl)]cycloimide chlor...

journal_title：Photochemistry and photobiology

authors： Feofanov A,Sharonov G,Grichine A,Karmakova T,Pljutinskaya A,Lebedeva V,Ruziyev R,Yakubovskaya R,Mironov A,Refregier M,Maurizot JC,Vigny P

更新日期：2004-02-01 00:00:00

abstract：:Antisense oligodeoxynucleotides directed against a 24-mer RNA derived from the long terminal repeat (LTR) region of HIV were linked to proto- and methylpyrroporphyrin and their zinc derivatives. The oligonucleotide-porphyrin conjugates were tested for their ability to induce photodamage on the target RNA. Upon hybridi...

journal_title：Photochemistry and photobiology

authors： Mastruzzo L,Woisard A,Ma DD,Rizzarelli E,Favre A,Le Doan T

更新日期：1994-10-01 00:00:00

abstract：:Herpes simplex virus (HSV) normally causes vescular lesions on mucocutaneous surfaces but can also cause encephalitis. The virus can reactivate from the latent state in neurons to form recrudescent lesions. One common stimulus for reactivation is exposure to sunlight. In the present study, the effects of irradiating r...

journal_title：Photochemistry and photobiology

authors： Garssen J,van der Molen R,de Klerk A,Norval M,van Loveren H

更新日期：2000-11-01 00:00:00

abstract：:Photochemo and photodynamic therapies are minimally invasive approaches for the treatment of cancers and powerful weapons for competing bacterial resistance to antibiotics. Synthetic and naturally occurring quinazolinones are considered privileged anticancer and antibacterial agents, with several of them to have emerg...

journal_title：Photochemistry and photobiology

authors： Panagopoulos A,Balalas T,Mitrakas A,Vrazas V,Katsani KR,Koumbis AE,Koukourakis MI,Litinas KE,Fylaktakidou KC

更新日期：2021-01-01 00:00:00

abstract：:Ultraviolet photolesions endow DNA with distinct structural and dynamic properties. Biophysical studies of photoproduct-containing DNA have shown that these lesions affect the mutagenic properties of DNA and damage recognition by DNA repair systems. Recently obtained high-resolution cocrystal structures of damaged DNA...

journal_title：Photochemistry and photobiology

authors： Park CJ,Lee JH,Choi BS

更新日期：2007-01-01 00:00:00

abstract：:The interaction with amino acids of the excited states of the N-oxide resazurin and its deoxygenation product resorufin, has been studied in aqueous solution at pH 7.5. Steady-state and time-resolved studies show that the fluorescence is quenched by amino acids. Complexation of the dyes in the ground state with aromat...

journal_title：Photochemistry and photobiology

authors： Villegas ML,Bertolotti SG,Previtali CM,Encinas MV

更新日期：2005-07-01 00:00:00

abstract：:A noninvasive in situ fluorescence-based method for the quantification of the photosensitizer chloroaluminum disulfonated phthalocyanine was compared to the highly accurate but nonreal time ex vivo spectrofluorometry method. Our in vivo fluorescence technique is designed to allow real-time assessment of photosensitize...

journal_title：Photochemistry and photobiology

authors： Lee CC,Pouge BW,Strawbridge RR,Moodie KL,Bartholomew LR,Burke GC,Hoopes PJ

更新日期：2001-09-01 00:00:00

abstract：:There are controversial reports in the literature concerning the reactivity of singlet oxygen ((1)O(2)) with the redox probe 2',7'-dichlorodihydrofluorescein (DCFH). By carefully preparing solutions in which (1)O(2) is quantitatively generated in the presence of DCFH, we were able to show that the formation rate of th...

journal_title：Photochemistry and photobiology

authors： Daghastanli NA,Itri R,Baptista MS

更新日期：2008-09-01 00:00:00

abstract：:Mitochondria have been implicated as a primary subcellular site of porphyrin localization and photodestruction. However, other organelles including the cell membrane, lysosomes and nucleus have been shown to be damaged by hematoporphyrin derivative (HpD) photosensitized destruction as well. In this study we attempted ...

journal_title：Photochemistry and photobiology

authors： Shulok JR,Wade MH,Lin CW

更新日期：1990-04-01 00:00:00

abstract：:The proton channels of the bacteriorhodopsin (BR) proton pump contain bound water molecules. The channels connect the purple membrane surfaces with the protonated retinal Schiff base at the membrane center. Films of purple membrane equilibrated at low relative humidity display a shift of the 570 nm retinal absorbance ...

journal_title：Photochemistry and photobiology

authors： Renthal R,Gracia N,Regalado R

更新日期：2000-11-01 00:00:00

abstract：:Several studies in the literature indicate that histones (lysine rich proteins found associated with DNA in eukaryotic chromatin), as well as poly-L-lysine, can be photocross-linked by ultraviolet (UV) light to DNA in which 5-bromo-2'-deoxyuridine has been substituted for thymidine. To gain some insight into the possi...

journal_title：Photochemistry and photobiology

authors： Shetlar MD,Rose RB,Hom K,Shaw AA

更新日期：1991-05-01 00:00:00

abstract：:The growing resistance to antibiotics has rendered antimicrobial photodynamic inactivation (PDI) an attractive alternative treatment modality for infectious diseases. Chitosan (CS) was shown to further potentiate the PDI effect of photosensitizers and was therefore used in this study to investigate its ability to pote...

journal_title：Photochemistry and photobiology

authors： Chen CP,Chen CT,Tsai T

更新日期：2012-05-01 00:00:00

abstract：:The significance of human cutaneous pigmentation lies in its protective role against sun-induced DNA damage and photocarcinogenesis. Fair skin and red hair are characterized by a low eumelanin to pheomelanin ratio, and have been associated with increased risk of skin cancer. Cutaneous pigmentation is a complex genetic...

journal_title：Photochemistry and photobiology

authors： Dessinioti C,Antoniou C,Katsambas A,Stratigos AJ

更新日期：2011-09-01 00:00:00

abstract：:Low-power lasers are commonly used in human medicine for treatment of various pathological conditions, but mechanisms of their healing effects are still poorly understood. The results of this study provide information related to these effects at the cellular level. Two different protozoan species, Euglena gracilis and...

journal_title：Photochemistry and photobiology

authors： Koutna M,Janisch R,Unucka M,Svobodnik A,Mornstein V

更新日期：2004-11-01 00:00:00

abstract：:Using normal, untransformed, human fibroblasts, the effectiveness of aminolevulinic (ALA)-mediated photodynamic therapy (PDT) was investigated in terms of both clonogenic survival and DNA damage. The response of normal fibroblasts was then compared with Gorlin syndrome-derived fibroblasts (basal cell nevus syndrome [B...

journal_title：Photochemistry and photobiology

authors： Haylett AK,Ward TH,Moore JV

更新日期：2003-10-01 00:00:00

abstract：:A solution of iodouracil (0.2 mg/mL) and KI (0.1 M) in 0.23 M borate buffer (pH 7) forms triiodide upon exposure to UVB. In the presence of thyodene, the blue starch-iodine complex is formed, the intensity of which is proportional to the amount of UVB exposure. Studies were conducted using either a sunlamp or solar ir...

journal_title：Photochemistry and photobiology

authors： Rahn R,Lee MA

更新日期：1998-08-01 00:00:00