Abstract:
:Genomic analysis of circulating, cell-free DNA (cfDNA) is being used extensively for molecular diagnostics. Many approaches rely on the construction of cfDNA genomic libraries, targeted retrieval of specific genomic regions and analysis by next-generation DNA sequencing. Several steps during sample preparation require isolation of DNA fragments within a particular size range. In this Benchmark article, two related methods for size-selective DNA fragment enrichment are described.
journal_name
Biotechniquesjournal_title
BioTechniquesauthors
Raymond CKdoi
10.2144/btn-2019-0071subject
Has Abstractpub_date
2019-10-01 00:00:00pages
188-191issue
4eissn
0736-6205issn
1940-9818journal_volume
67pub_type
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