Alternative method in Galleria mellonella larvae to study biofilm infection and treatment.

abstract：:The effect of recombinant Brugia malayi pepsin inhibitor (rBm33) on human monocytes/macrophages has been examined using THP-1 cells. THP-1 cells stimulated with rBm33 showed enhanced levels of expression of pro-inflammatory cytokines (IL-1β, TNF-α, IL-6) and diminished levels of IL-12, iNOS and anti-inflammatory cytok...

journal_title：Microbial pathogenesis

authors： Sreenivas K,Vijayan K,Babu S,Narayanan RB

更新日期：2012-07-01 00:00:00

abstract：:Biosynthesis of nanoparticles by fermented plants using microbes is an eco-friendly and cost-effective process. In this study, we used the fungus Aspergillus orayzae for the fermentation process. The aqueous extract of fermented Lupin (AEFL) possesses the ability to reduce selenium ion in the presence of gamma rays ev...

journal_title：Microbial pathogenesis

authors： Mosallam FM,El-Sayyad GS,Fathy RM,El-Batal AI

更新日期：2018-09-01 00:00:00

abstract：:Due to the growing number of multi-resistant Candida spp., adjuvant treatments that may help combat these fungal pathogens are relevant and useful. This study evaluated the immunomodulation and anti-Candida activity of Lactobacillus rhamnosus (LR), Lactobacillus acidophilus and Lactobacillus paracasei suspensions, eit...

journal_title：Microbial pathogenesis

authors： de Oliveira FE,Rossoni RD,de Barros PP,Begnini BE,Junqueira JC,Jorge AOC,Leão MVP,de Oliveira LD

更新日期：2017-09-01 00:00:00

abstract：:Brucellosis is a worldwide zoonotic infectious disease that has significant economic effects on animal production and human health. The host macrophage -Brucella interaction is critical to the establishment of infections. Thus, the kinetic transcriptional profile of gene expression in macrophages infected with the Bru...

journal_title：Microbial pathogenesis

authors： Liu Q,Han W,Sun C,Zhou L,Ma L,Lei L,Yan S,Liu S,Du C,Feng X

更新日期：2012-05-01 00:00:00

abstract：:Yersina enterocolitica-like species have not been extensively studied regarding its pathogenic potential. This work aimed to assess the pathogenic potential of some Y. enterocolitica-like strains by evaluating the presence of virulence-related genes by PCR and their ability to adhere to and invade Caco-2 and HEp-2 cel...

journal_title：Microbial pathogenesis

authors： Imori PF,Passaglia J,Souza RA,Rocha LB,Falcão JP

更新日期：2017-03-01 00:00:00

abstract：:The involvement of nitric oxide (NO) in host defense and cytoprotective functions in murine salmonellosis has been reported. Salmonella mutants with the altered sigma factor RpoS (sigmaS) are less virulent and are susceptible to various stresses. This study investigated the role of the rpoS gene of Salmonella enterica...

journal_title：Microbial pathogenesis

authors： Alam MS,Zaki MH,Yoshitake J,Akuta T,Ezaki T,Akaike T

更新日期：2006-03-01 00:00:00

abstract：:The addition of maltose to the growth media of Actinobacillus pleuropneumonia (serotype 1) resulted in the induction of an outer membrane protein (OMP) with a molecular mass of 42 kDa. This protein had porin-like properties in that it was peptidoglycan-associated and was resistant to proteolysis by trypsin. A pleuropn...

journal_title：Microbial pathogenesis

authors： Deneer HG,Potter AA

更新日期：1989-06-01 00:00:00

abstract：:Lung cancer, the leading cause of cancer mortality, needs urgent development of newly qualified diagnostic and therapeutic biomarkers. Recently, Human Endogenous Retroviruses (HERVs) have been introduced for cancer diagnosis. In this case-control study, we have collected blood samples from 60 lung cancer patients and ...

journal_title：Microbial pathogenesis

authors： Zare M,Mostafaei S,Ahmadi A,Azimzadeh Jamalkandi S,Abedini A,Esfahani-Monfared Z,Dorostkar R,Saadati M

更新日期：2018-02-01 00:00:00

abstract：:As an economic devastating virus, porcine reproductive and respiratory syndrome virus (PRRSV) has spread globally, and seriously hinders the healthy development of the swine industry worldwide. In recent years, however, recombinant PRRSV strains are continuously emerging, resulting in the death of a large number of pi...

journal_title：Microbial pathogenesis

authors： Song Z,Zhang Q,Chen Y,Shen H,Yang G,Jiang P,Chen JL,Lin L

更新日期：2020-12-01 00:00:00

abstract：:VirB plays a central role in the regulation of virulence of Shigella flexneri. It acts as a transcriptional activator and is itself transcriptionally activated by another virulence protein, VirF. Experiments were performed in order to identify the site upstream of virB at which VirF binds in order to activate transcri...

journal_title：Microbial pathogenesis

authors： Jost BH,Adler B

更新日期：1993-06-01 00:00:00

abstract：:Upon oxygen shift-down, Mycobacterium tuberculosis complex bacteria can induce a genetic program characterized by halted duplication, which is called Non-replicating persistence (NRP). During this phase, at least 48 genes, collectively named Dormancy survival regulator (DosR) regulon, are important for the long-term s...

journal_title：Microbial pathogenesis

authors： Jiménez BA,Hinojoza-Loza E,Flores-Valdez MA,Prado-Montes de Oca E,Allen K,Estrada-Chávez C,Herrera-Rodríguez S,Flores-Fernández JM,Martínez-Velázquez M,Hernández-Gutiérrez R,Alvarez AH

更新日期：2013-08-01 00:00:00

abstract：:In the present study hexane, benzene, ethyl acetate and ethanol extracts of Pithecellobium dulce root were prepared using soxhlet extractor. The extracts were evaluated for antibacterial activity against one Gram positive (Staphylococcus aureus) and three Gram negative (Acetobacter aceti, Acetobacter aceti, Klebsiella...

journal_title：Microbial pathogenesis

authors： Bhat MA,Malik RA,Prakash P,Lone AM

更新日期：2018-03-01 00:00:00

abstract：:Group G streptococci have on their surface antiphagocytic M protein-like antigens. To determine if these organisms have genes similar to the M protein genes of Streptococcus pyogenes (group A), DNA from independent group G isolates of human and animal origin were tested for homology to probes representing sequences en...

journal_title：Microbial pathogenesis

authors： Simpson WJ,Robbins JC,Cleary PP

更新日期：1987-11-01 00:00:00

abstract：:Fimbrial adhesins and hemolysins contribute to pathogenicity of extraintestinal Escherichia coli isolates causing urinary tract infections (UTI), sepsis and new born meningitis (NBM). Using gene cloning techniques and pulse field electrophoresis in combination with Southern hybridizations it was demonstrated that the ...

journal_title：Microbial pathogenesis

authors： Hacker J,Bender L,Ott M,Wingender J,Lund B,Marre R,Goebel W

更新日期：1990-03-01 00:00:00

abstract：:Protective immunity against Salmonella infection was studied in a mouse model. To study specificity of protection we used smooth (O-4,5,12) and rough vaccines; live and killed vaccines of both types were compared. The protection was assessed by enumerating the number of bacteria in the livers, and by following surviva...

journal_title：Microbial pathogenesis

authors： Muotiala A,Hovi M,Mäkelä PH

更新日期：1989-01-01 00:00:00

abstract：:Many pathogens of the Pasteurellaceae and Neisseriaceae possess a surface receptor that binds transferrin (Tf) as an initial step in an iron acquisition process. This receptor is comprised of two proteins, transferrin binding protein A (TbpA) and transferrin binding protein B (TbpB). Since the ability to recognize the...

journal_title：Microbial pathogenesis

authors： Retzer MD,Yu Rh,Zhang Y,Gonzalez GC,Schryvers AB

更新日期：1998-10-01 00:00:00

abstract：:Toxoplasma gondii is one of the most successful intracellular protozoan parasites in the world, which can infect most warm-blooded animals including foxes in the world and cause toxoplasmosis. This is the first meta-analysis to assess the overall prevalence and potential risk factors of T. gondii among foxes in the wo...

journal_title：Microbial pathogenesis

authors： Wei XY,Gao Y,Lv C,Wang W,Chen Y,Zhao Q,Gong QL,Zhang XX

更新日期：2020-12-28 00:00:00

abstract：:Microbial adherence to host cells is an early key step in the establishment of infection. During the course of Legionnaire's disease, Legionella interactions with host cells are best documented for resident macrophages. However, L. pneumophila can also replicate within type I and type II pneumocytes, which cover almos...

journal_title：Microbial pathogenesis

authors： Yaradou DF,Raze D,Ginevra C,Ader F,Doléans-Jordheim A,Vandenesch F,Menozzi FD,Etienne J,Jarraud S

更新日期：2007-11-01 00:00:00

abstract：:Lmof2365_2117 is a Listeria monocytogenes putative cell wall surface anchor protein with a conserved domain found in collagen binding proteins. We constructed a deletion mutation in lmof2365_2117 in serotype 4b strain F2365, evaluated its virulence, and determined its ability to adhere and invade colonic epithelial ce...

journal_title：Microbial pathogenesis

authors： Reddy S,Akgul A,Karsi A,Abdelhamed H,Wills RW,Lawrence ML

更新日期：2016-03-01 00:00:00

abstract：:Aeromonas hydrophila is one of the main causative agent of high mortality and significative economic losses in aquaculture and has become increasingly resistant to conventional antibiotics. One feasible alternative to control and treat it is the use of essential oils. This study aimed to evaluate A. hydrophila suscept...

journal_title：Microbial pathogenesis

authors： F Souza C,Baldissera MD,A Vaucher R,Lopes LQ,Vizzotto BS,Raffin RP,Santos RC,L da Veiga M,U M da Rocha MI,Stefani LM,Baldisserotto B

更新日期：2016-09-01 00:00:00

abstract：:Host cell invasion is important for periodontal pathogens in evading host defenses and spreading into deeper areas of the periodontal tissue. Treponema denticola has been implicated in a number of potentially pathogenic processes, including periodontal tissue penetration. Here we tested the ability of T. denticola str...

journal_title：Microbial pathogenesis

authors： Inagaki S,Kimizuka R,Kokubu E,Saito A,Ishihara K

更新日期：2016-05-01 00:00:00

abstract：:Staphylococcus aureus small-colony variants (SCVs) and biofilms are linked to chronic infections. It is known that the presence of aminoglycoside antibiotics may contribute to the emergence of SCVs and it is thought that molecular mechanisms are involved in the ability of S. aureus to adopt this phenotype. No study ha...

journal_title：Microbial pathogenesis

authors： Mitchell G,Brouillette E,Séguin DL,Asselin AE,Jacob CL,Malouin F

更新日期：2010-01-01 00:00:00

abstract：:The gene clusters encoding various P-fimbriae (F7(1), F7(2), F9 and F11) were compared. Deletion plasmids that lack the gene encoding the fimbrillin were derived from these gene clusters. Introduction of these deletion plasmids into an E. coli K12 strain resulted in non-fimbriated cells that still showed mannose-resis...

journal_title：Microbial pathogenesis

authors： van Die I,Zuidweg E,Hoekstra W,Bergmans H

更新日期：1986-02-01 00:00:00

abstract：:We have developed a system whereby heterologous DNA encoding an antigen from an enteropathogen may be recombined into the chromosome of an attenuated Salmonella carrier strain. The system involves two steps: (i) integration of a hisOG deletion mutation into the chromosome; (ii) replacement of the hisOG deletion by the...

journal_title：Microbial pathogenesis

authors： Hone D,Attridge S,van den Bosch L,Hackett J

更新日期：1988-12-01 00:00:00

abstract：:The emergence of extensively drug-resistant (XDR) Acinetobacter baumannii strains and the limited number of efficacious antibiotics demonstrate an urgent need to develop novel agents to treat infections caused by this dangerous pathogen. To find antimicrobial peptides against A. baumannii growing either in planktonic ...

journal_title：Microbial pathogenesis

authors： Irani N,Basardeh E,Samiee F,Fateh A,Shooraj F,Rahimi A,Shahcheraghi F,Vaziri F,Masoumi M,Pazhouhandeh M,Siadat SD,Kazemi-Lomedasht F,Jamnani FR

更新日期：2018-08-01 00:00:00

abstract：:Salmonella are causes of livestock, poultry, and other animal diseases but they also have the potential to infect people. Currently, antibiotics are the first choice for treatment of Salmonella infections. Thus, the utility of phage has become the research focus for scientists for several reasons. There are efficient,...

journal_title：Microbial pathogenesis

authors： Tang F,Zhang P,Zhang Q,Xue F,Ren J,Sun J,Qu Z,Zhuge X,Li D,Wang J,Jiang M,Dai J

更新日期：2019-01-01 00:00:00

abstract：:The enteropathogenic potential of 32 Vibrio cholerae O1 isolates that do not produce cholera toxin was examined in the orally inoculated, sealed adult mouse model. Live cultures (2 x 10(10) cfu/ml) of 7/16 clinical and 6/16 environmental isolates produced a positive intestinal fluid accumulation (FA) ratio that reache...

journal_title：Microbial pathogenesis

authors： Moyenuddin M,Wachsmuth K,Richardson SH,Cook WL

更新日期：1992-06-01 00:00:00

abstract：:Clinical isolates of Pseudomonas aeruginosa are either invasive or cytotoxic towards mammalian epithelial cells, endothelial cells, and macrophages. Invasion requires host cell actin cytoskeleton function, and ExsA-regulated proteins of P. aeruginosa that inhibit invasion (ExoS and ExoT) can disrupt the cytoskeleton. ...

journal_title：Microbial pathogenesis

authors： Evans DJ,Kuo TC,Kwong M,Van R,Fleiszig SM

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:The non-coding RNA rprA can increase the resistance to ampicillin in Escherichia coli. METHODS:Bacterial DNA was extracted by boiling method and then amplified using polymerase chain reaction (PCR) with two different primer sets. Recombinant pET28a/rprA-sense and -antisense plasmids were separately transfer...

journal_title：Microbial pathogenesis

authors： Sahni A,Hajjari M,Raheb J,Foroughmand AM,Asgari M

更新日期：2019-04-01 00:00:00

abstract：:Anthrax lethal factor (LF), a Zn(2+)-dependent metalloprotease, is a key virulence component of anthrax toxin. Here, we used proteolytic assay-based screening to identify novel LF inhibitors from a naturally extracted chemical library. The screening identified four compounds that inhibited in vitro proteolytic activit...

journal_title：Microbial pathogenesis

authors： Park HC,Sung SR,Lim SM,Lee JS,Kim SK,Yoon MY

更新日期：2012-08-01 00:00:00