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The emergence of a novel recombinant porcine reproductive and respiratory syndrome virus with an amino acid insertion in GP5 protein.

Abstract：

:As an economic devastating virus, porcine reproductive and respiratory syndrome virus (PRRSV) has spread globally, and seriously hinders the healthy development of the swine industry worldwide. In recent years, however, recombinant PRRSV strains are continuously emerging, resulting in the death of a large number of pigs in China. In this study, we reported a NADC30-like PRRSV strain GD1909, a recombinant virus, which may originate from NADC30-like and HUN4-like strains. The GP5 protein of GD1909 strain has an asparagine insertion at position 60 and has more complex glycosylation pattern. This should be helpful for a better understanding of PRRSV molecular epidemiology and the prevention of PRRSV infection in the future.

journal_name

Microb Pathog

journal_title

Microbial pathogenesis

authors

Song Z,Zhang Q,Chen Y,Shen H,Yang G,Jiang P,Chen JL,Lin L

doi

10.1016/j.micpath.2020.104573

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

104573

eissn

0882-4010

issn

1096-1208

pii

S0882-4010(20)30939-6

journal_volume

149

pub_type

杂志文章

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