Mutation of csk, encoding the C-terminal Src kinase, reduces Pseudomonas aeruginosa internalization by mammalian cells and enhances bacterial cytotoxicity.

abstract：:In this experimental study, the Allium essential oil (AHEO) was extracted through the hydrodistillation method. AHEO components were identified through gas chromatography/mass spectrometry (GC/MS), and its antioxidant properties and total phenolic content were examined through the methods of 2,2-diphenyl-1-picrylhydra...

journal_title：Microbial pathogenesis

authors： Alizadeh Behbahani B,Imani Fooladi AA

更新日期：2018-01-01 00:00:00

abstract：:A variant of Vero toxin 2 (VT2), or Shiga-like toxin II (SLT-II) was purified from a cloned strain of Escherichia coli carrying a gene that encodes SLT-IIva, which is most closely related to SLT-IIv (VT2vp, VTe) in its nucleotide sequence. The purified SLT-IIva showed a slight difference from the purified SLT-IIv (VT2...

journal_title：Microbial pathogenesis

authors： Ohmura M,Cao C,Karasawa T,Okuda J,Kurazono H,Gannon VP,Gyles CL,Takeda Y

更新日期：1993-11-01 00:00:00

abstract：:This study aimed to investigate the mechanism of lipopolysaccharide (LPS) released in the rumen on epithelium barrier function of goats fed a HC diet. Twelve Boer goats were randomly divided into two groups: low-concentrate(LC) diet and high-concentrate(HC) diet treatment. We found that the pH of rumen fluid in the HC...

journal_title：Microbial pathogenesis

authors： Zhang K,Meng M,Gao L,Tu Y,Bai Y

更新日期：2019-06-01 00:00:00

abstract：:Clostridium difficile causes serious and potentially fatal inflammatory diseases of the colon. Two large protein toxins, TcdA and TcdB, have been clearly implicated in pathogenesis. The goal of this study was to determine whether the glucosyltransferase activity of the toxins is critical for the induction of tumor nec...

journal_title：Microbial pathogenesis

authors： Sun X,He X,Tzipori S,Gerhard R,Feng H

更新日期：2009-06-01 00:00:00

abstract：:Group G streptococci have on their surface antiphagocytic M protein-like antigens. To determine if these organisms have genes similar to the M protein genes of Streptococcus pyogenes (group A), DNA from independent group G isolates of human and animal origin were tested for homology to probes representing sequences en...

journal_title：Microbial pathogenesis

authors： Simpson WJ,Robbins JC,Cleary PP

更新日期：1987-11-01 00:00:00

abstract：:Pseudomonas aeruginosa (PAO1) is an important opportunistic pathogen that thrives in various environments. It is known that the structural variations of the lipopolysaccharide (LPS), including lipid A moiety play an important role in encountering environmental changes. Genes PA3242 and PA0011 have recently been report...

journal_title：Microbial pathogenesis

authors： Liang Y,Guo Z,Gao L,Guo Q,Wang L,Han Y,Duan K,Shen L

更新日期：2016-12-01 00:00:00

abstract：:Lung cancer, the leading cause of cancer mortality, needs urgent development of newly qualified diagnostic and therapeutic biomarkers. Recently, Human Endogenous Retroviruses (HERVs) have been introduced for cancer diagnosis. In this case-control study, we have collected blood samples from 60 lung cancer patients and ...

journal_title：Microbial pathogenesis

authors： Zare M,Mostafaei S,Ahmadi A,Azimzadeh Jamalkandi S,Abedini A,Esfahani-Monfared Z,Dorostkar R,Saadati M

更新日期：2018-02-01 00:00:00

abstract：:Group A streptococci demonstrate a number of distinct ways to interact with the human fibrinolytic system to acquire unregulatable cell-surface enzymatic activity. Interactions between bacteria, fibrinogen, streptokinase and plasminogen resulted in acquisition of cell-associated enzymatic activity that can lyse fibrin...

journal_title：Microbial pathogenesis

authors： Wang H,Lottenberg R,Boyle MD

更新日期：1995-03-01 00:00:00

abstract：:Thymol and carvacrol from the class of monoterpene phenols are one of the most potent plant essential oil components possessing antimicrobial effects. Known for their wide bioactive spectrum, these positional isomers of isopropyl cresol deplete ergosterol content, compromise membrane permeability, block efflux pumps a...

journal_title：Microbial pathogenesis

authors： Khan A,Ahmad A,Ahmad Khan L,Padoa CJ,van Vuuren S,Manzoor N

更新日期：2015-03-01 00:00:00

abstract：:Clostridium perfringens (C. perfringens), a Gram-positive bacterium, is one of the main causing piglet diarrhea, which leads serious economic loss in the world swine industries. Generally, the innate immune response plays a critical role in host defense against pathogen invasion. TLR4, a member of the TLR (Toll-like r...

journal_title：Microbial pathogenesis

authors： Shi H,Huang X,Yan Z,Yang Q,Wang P,Li S,Sun W,Gun S

更新日期：2019-10-01 00:00:00

abstract：:Avian sarcoma virus (ASV)-induced tumor cells that are derived from regressing neoplasms contain about 75% less pp60src kinase activity than do progressively-growing tumor cells. Paradoxically, the polyadenylated RNAs extracted from 'regressor' cells found in regressing neoplasms are much more productive than those fr...

journal_title：Microbial pathogenesis

authors： Poulin L,Wainberg MA

更新日期：1987-02-01 00:00:00

abstract：:Probiotic bacteria with antibacterial activity is of desirable trait since they can check the growth of pathogenic bacteria besides exhibiting health benefits to host. Aim of this study was to characterize Bacillus licheniformis MCC 2512T (MCC 2512), a potential probiotic culture for its ability to produce subtilin-li...

journal_title：Microbial pathogenesis

authors： Halami PM

更新日期：2019-03-01 00:00:00

abstract：:In the present study hexane, benzene, ethyl acetate and ethanol extracts of Pithecellobium dulce root were prepared using soxhlet extractor. The extracts were evaluated for antibacterial activity against one Gram positive (Staphylococcus aureus) and three Gram negative (Acetobacter aceti, Acetobacter aceti, Klebsiella...

journal_title：Microbial pathogenesis

authors： Bhat MA,Malik RA,Prakash P,Lone AM

更新日期：2018-03-01 00:00:00

abstract：:Cervical cancer is a growing and serious problem world-wide in women, but more acute in developing countries especially in Indian subcontinent. The main causative agent for the disease is Human Papilloma Virus (HPV). The history of the cervical cancer goes back to eighteenth century as the HPV infection is reported si...

journal_title：Microbial pathogenesis

authors： Shah UJ,Nasiruddin M,Dar SA,Khan MKA,Akhter MR,Singh N,Rabaan AA,Haque S

更新日期：2020-06-01 00:00:00

abstract：:In the present work two key regulator proteins, monomeric MipZ of Caulobacter vibrioides (similar to Pseudomonas aeruginosa) and Pyruvate kinase of Staphylococcus aureus were docked with curcumin, the wonder molecule from the spice turmeric and structures of its twelve analogues were designed, synthesized and tested i...

journal_title：Microbial pathogenesis

authors： Shrivash MK,Mishra S,UpmaNarain,Pandey J,Misra K

更新日期：2018-10-01 00:00:00

abstract：:Like most microorganisms, Neisseria gonorrhoeae alters gene expression in response to iron availability. The ferric uptake regulator Fur has been shown to be involved in controlling this response, but the extent of this involvement remains unknown. It is known that in addition to working directly to repress gene expre...

journal_title：Microbial pathogenesis

authors： Ducey TF,Jackson L,Orvis J,Dyer DW

更新日期：2009-03-01 00:00:00

abstract：:Thanks to the progress and decreasing costs in genome sequencing technologies, more than 250,000 bacterial genomes are currently available in public databases, covering most, if not all, of the major human-associated phylogenetic groups of these microorganisms, pathogenic or not. In addition, for many of them, sequenc...

journal_title：Microbial pathogenesis

authors： Anani H,Zgheib R,Hasni I,Raoult D,Fournier PE

更新日期：2020-12-01 00:00:00

abstract：:The accumulation of inflammatory cells in the peritoneal cavity of C57BL/6 mice was examined following intraperitoneal injection of Entamoeba histolytica trophozoites. Two different strains of E. histolytica were used: a virulent strain (IP:0682:1) and a non-virulent strain (DKB). Injection of 10(6) trophozoites of ei...

journal_title：Microbial pathogenesis

authors： Ghadirian E,Stevenson MM

更新日期：1987-09-01 00:00:00

abstract：:The objective of this study was to evaluate the influence of microbe-microbe interactions to identify a strain of Lactobacillus that could reduce the filamentation of Candida albicans ATCC 18804 using in vitro and in vivo models. Thus presenting a probiotic effect against the fungal pathogen. First, we analyzed the ab...

journal_title：Microbial pathogenesis

authors： de Barros PP,Scorzoni L,Ribeiro FC,Fugisaki LRO,Fuchs BB,Mylonakis E,Jorge AOC,Junqueira JC,Rossoni RD

更新日期：2018-04-01 00:00:00

abstract：:Uropathogenic Escherichia coli (UPEC) is the most prevalent causative agent of urinary tract infections (UTIs). The pathogenicity of UPEC relies on the expression of virulence factors which could be regulated by intercellular signal molecules. Our previous study found that sub-minimal inhibitory concentration ceftazid...

journal_title：Microbial pathogenesis

authors： Feng W,Zhang L,Yuan Q,Wang Y,Yao P,Xia P,Sun F

更新日期：2021-01-21 00:00:00

abstract：:The current study determined the ability of Francisella novicida to act as a live vaccine against the much more virulent, but closely related pathogen, Francisella tularensis. Live attenuated strains of the latter are effective vaccines against human tularemia. However, the molecular cause of their attenuation remains...

journal_title：Microbial pathogenesis

authors： Shen H,Chen W,Conlan JW

更新日期：2004-08-01 00:00:00

abstract：:The gene coding for serotype A of epidermolytic (exfoliative) toxin has been cloned from Staphylococcus aureus in Escherichia coli phage lambda and plasmid vectors. The coding sequence for eta was localised by subcloning and transposon Tn5 mutagenesis experiments. The eta gene was probably expressed from its natural p...

journal_title：Microbial pathogenesis

authors： O'Toole PW,Foster TJ

更新日期：1986-12-01 00:00:00

abstract：:Staphylococcus aureus expresses many Microbial Surface Recognizing Adhesive Matrix Molecules (MSCRAMM's) to recognize host extracellular matrix (ECM) molecules to initiate colonization. The MSCRAMM, fibronectin binding protein A (FnBPA), is an important adhesin for S. aureus infection. FnBPA also binds with fibrinogen...

journal_title：Microbial pathogenesis

authors： Ponnuvel S,Sankar S,Ponnuraj K

更新日期：2020-09-01 00:00:00

abstract：:Two-component regulatory proteins, histidine kinases and response regulators, function in bacteria as sensing and adaptive factors in response to a wide range of environmental stimuli. Conserved histidine and glycine regions of histidine kinase sensor proteins were used to design degenerate oligonucleotide primers for...

journal_title：Microbial pathogenesis

authors： Haydel SE,Dunlap NE,Benjamin WH Jr

更新日期：1999-04-01 00:00:00

abstract：INTRODUCTION:Pneumococcal infections have caused morbidity and mortality globally. Streptococcus pneumoniae (pneumococci) are commensal bacteria that colonize the nasopharynx, asymptomatically. From there, pneumococci can spread in the lungs causing pneumonia and disseminate in the bloodstream causing bacteremia (sepsi...

journal_title：Microbial pathogenesis

authors： Rahman NA,Sharudin A,Diah S,Muharram SH

更新日期：2017-09-01 00:00:00

abstract：:Repetitive tetranucleotide sequences of 5'-(CAAT)(n)-3' have been identified at the 5' end of an open reading frame (ORF) named lob1 from Haemophilus somnus strain 738. Based on sequence analysis, lob1 has 59% DNA homology to lex2B, which is involved in lipooligosaccharide (LOS) biosynthesis in H. influenzae. We now r...

journal_title：Microbial pathogenesis

authors： McQuiston JH,McQuiston JR,Cox AD,Wu Y,Boyle SM,Inzana TJ

更新日期：2000-05-01 00:00:00

abstract：:Staphylococcus aureus is a bacterial pathogen causing approximately 80% of all cases of human osteomyelitis. This bacterium can adhere to and become internalized by osteoblasts and previous studies indicate that osteoblasts are active in the internalization process. In the current study, we examined the roles of micro...

journal_title：Microbial pathogenesis

authors： Ellington JK,Reilly SS,Ramp WK,Smeltzer MS,Kellam JF,Hudson MC

更新日期：1999-06-01 00:00:00

abstract：:Lignin, a common natural polymers, is abundant and complex, and termites can break down and utilize the lignin in their food. In this study an attempt was made to isolate and characterize the lignolytic bacteria from termite (Reticulitermes chinensis Snyder) gut. Two strains (PY12 and MX5) with high lignin peroxidase ...

journal_title：Microbial pathogenesis

authors： Zhou H,Guo W,Xu B,Teng Z,Tao D,Lou Y,Gao Y

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Pseudomonas aeruginosa, an opportunistic pathogen, can cause serious health problems and produces several virulence factors. The most important of these factors is biofilm. Many studies suggest administration of new generation of antibiotics, as P. aeruginosa biofilm has developed high resistance to antimicro...

journal_title：Microbial pathogenesis

authors： Dolatabadi S,Moghadam HN,Mahdavi-Ourtakand M

更新日期：2018-05-01 00:00:00

abstract：:Until recently, glycoproteins had only been described in eukaryotes. However, advances in detection methods and genome analyses have allowed the discovery of N-linked or O-linked glycoproteins, similar to those found in eukaryotes, in some bacterial species. These prokaryotic glycoproteins play roles in adhesion, solu...

journal_title：Microbial pathogenesis

authors： Shoji M,Nakayama K

更新日期：2016-05-01 00:00:00