Mice sublethally infected with Francisella novicida U112 develop only marginal protective immunity against systemic or aerosol challenge with virulent type A or B strains of F. tularensis.

abstract：:In this study an attempt to address the effects of immunosuppression on pathogenesis of peste des petits ruminants (PPR) virus infection was undertaken. Cyclophosphamide and dexamethasone were used to immunosuppress the animals. The drug treated animals exhibited severe leukopaenia and lymphopaenia; one of the indicat...

journal_title：Microbial pathogenesis

authors： Jagtap SP,Rajak KK,Garg UK,Sen A,Bhanuprakash V,Sudhakar SB,Balamurugan V,Patel A,Ahuja A,Singh RK,Vanamayya PR

更新日期：2012-04-01 00:00:00

abstract：:Helicobacter pylori is a microorganism that in the last years has been associated with extragastric disorders such as respiratory diseases, however, its impact on lung is partially understood. The aim of this work was to study infection impact of H. pylori on the inflammatory markers expression at the pulmonary level ...

journal_title：Microbial pathogenesis

authors： Arismendi Sosa AC,Salinas Ibáñez AG,Pérez Chaca MV,Penissi AB,Gómez NN,Vega AE

更新日期：2020-02-26 00:00:00

abstract：:In order to characterize the toxicity of the hemorrhagic toxin of Clostridium sporogenes isolated from the rabbit with antibiotic-associated hemorrhagic diarrhoea, we studied the toxin productivity of C. sporogenes cultured in various media and the toxic effect of the partially purified preparation of the culture supe...

journal_title：Microbial pathogenesis

authors： Hara-Kudo Y,Ogura A,Noguchi Y,Terao K,Kumagai S

更新日期：1997-01-01 00:00:00

abstract：:The growth inhibitory effects of chicken egg white ovomacroglobulin (ovoM) on Serratia marcescens and Pseudomonas aeruginosa were studied. The growth of protease-producing strains was greater than that of the strains producing little protease, and was inhibited in a dose-dependent manner by ovoM, a potent protease inh...

journal_title：Microbial pathogenesis

authors： Miyagawa S,Nishino N,Kamata R,Okamura R,Maeda H

更新日期：1991-08-01 00:00:00

abstract：:Influence of both recombinant interferon gamma (r-IFN-gamma) and monoclonal anti-IFN-gamma on murine Salmonella typhimurium infection was studied in vivo. As a challenge we used either a virulent or an avirulent strain of S. typhimurium. The avirulent strain is unable to replicate in the mouse spleen. The effect of IF...

journal_title：Microbial pathogenesis

authors： Muotiala A,Mäkelä PH

更新日期：1990-02-01 00:00:00

abstract：:The clinical implications of recently discovered porcine circovirus 3 (PCV3) infections are still unknown. The potential role of this emerging virus in reproductive loss in swine has been described. Herein, we report a high prevalence of PCV3 in mummified fetuses from sows maintained in modern farms in Rio Grande do S...

journal_title：Microbial pathogenesis

authors： Dal Santo AC,Cezario KC,Bennemann PE,Machado SA,Martins M

更新日期：2020-04-01 00:00:00

abstract：:The ica operon and aap gene are important factors for Staphylococcus epidermidis biofilm formation. However, we found 15 out of 101 S. epidermidis strains isolated from patients had both the ica operon and the aap gene in the genome but could not form biofilms (ica(+)aap(+)/BF(-) isolates). Compared with standard stra...

journal_title：Microbial pathogenesis

authors： Wu Y,Liu J,Jiang J,Hu J,Xu T,Wang J,Qu D

更新日期：2014-11-01 00:00:00

abstract：:Mannheimia(Pasteurella)haemolytica serotype 1 is the primary causative agent responsible for bovine pneumonic mannheimiosis, also known as shipping fever in cattle. The bacterium produces a variety of virulence factors, foremost of which is the exotoxic leukotoxin. The leukotoxin is a calcium-dependent cytolysin that ...

journal_title：Microbial pathogenesis

authors： Thumbikat P,Briggs RE,Kannan MS,Maheswaran SK

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Canine distemper virus (CDV) can cause a highly contagious disease to canid. However, how CDV affects peripheral blood lymphocyte (PBL) remains unclear. METHODS:In this study, CDV infected PBL was cultured to investigate the effect of CDV on the differentiation of lymphocytes and the mRNA expression of infl...

journal_title：Microbial pathogenesis

authors： Song K,Wu ZM,Peng LY,Yuan M,Huang JN,Zhang CL,Fu BD,Yi PF,Shen HQ

更新日期：2019-06-01 00:00:00

abstract：:This work illustrates a new role for the membranotropic peptide gH625 and its derivative gH625-GCGKKK in impairing formation of polymicrobial biofilms. Mixed biofilms composed of Candida and bacterial species cause frequently infections and failure of medical silicone devices and also show a major drug resistance than...

journal_title：Microbial pathogenesis

authors： de Alteriis E,Lombardi L,Falanga A,Napolano M,Galdiero S,Siciliano A,Carotenuto R,Guida M,Galdiero E

更新日期：2018-12-01 00:00:00

abstract：:Avian sarcoma virus (ASV)-induced tumor cells that are derived from regressing neoplasms contain about 75% less pp60src kinase activity than do progressively-growing tumor cells. Paradoxically, the polyadenylated RNAs extracted from 'regressor' cells found in regressing neoplasms are much more productive than those fr...

journal_title：Microbial pathogenesis

authors： Poulin L,Wainberg MA

更新日期：1987-02-01 00:00:00

abstract：:Nonencapsulated Haemophilus influenzae frequently persists in the lungs of chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) patients for prolonged periods of time. The bacteria are not eradicated by antibiotic treatment of the patients or by specific antibodies that are found in the sputum and ser...

journal_title：Microbial pathogenesis

authors： van Schilfgaarde M,Eijk P,Regelink A,van Ulsen P,Everts V,Dankert J,van Alphen L

更新日期：1999-05-01 00:00:00

abstract：:Host cell invasion is important for periodontal pathogens in evading host defenses and spreading into deeper areas of the periodontal tissue. Treponema denticola has been implicated in a number of potentially pathogenic processes, including periodontal tissue penetration. Here we tested the ability of T. denticola str...

journal_title：Microbial pathogenesis

authors： Inagaki S,Kimizuka R,Kokubu E,Saito A,Ishihara K

更新日期：2016-05-01 00:00:00

abstract：:In Salmonella enterica serovar Typhimurium, MgtC and PagC are positively regulated by the PhoP-PhoQ two-component system, which is activated under magnesium deprivation. Both MgtC and PagC are of unknown function but have been involved in intramacrophage survival. We have found that the amount of PagC is lowered in a ...

journal_title：Microbial pathogenesis

authors： Alix E,Miki T,Felix C,Rang C,Figueroa-Bossi N,Demettre E,Blanc-Potard AB

更新日期：2008-09-01 00:00:00

abstract：:Streptococcus pneumoniae attach to human pharyngeal epithelial cells through the specific interaction of bacterial surface adhesins with glycoconjugate receptors. The present study defines the adhesin as a molecule bridging between an anchoring site in the bacterial cell wall and the epithelial cell receptor. The natu...

journal_title：Microbial pathogenesis

authors： Andersson B,Beachey EH,Tomasz A,Tuomanen E,Svanborg-Edén C

更新日期：1988-04-01 00:00:00

abstract：:To examine the genetic control of acute and late disease induced by a murine coronavirus, strain JHM (JHMV), BALB/cHeA, STS/A, F1 hybrids and 13 recombinant inbred (RI) strains between BALB/cHeA and STS/A mouse strains were inoculated intracerebrally with 100 pfu of JHMV. All the BALB/cHeA mice died within 2 weeks fro...

journal_title：Microbial pathogenesis

authors： Kyuwa S,Yamaguchi K,Toyoda Y,Fujiwara K,Hilgers J

更新日期：1992-02-01 00:00:00

abstract：:We aimed to identify key pathways to further explore the molecular mechanism underlying pediatric pneumonia using differential pathway network which integrated protein-protein interactions (PPI) data and pathway information. PPI data and pathway information were obtained from STRING and Reactome database, respectively...

journal_title：Microbial pathogenesis

authors： Yang JB,Luo R,Yan Y,Chen Y

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Brucella is a Gram-negative and facultative intracellular organism that causes brucellosis, a common zoonotic disease. Over 500,000 people are annually affected by brucellosis. Brucella is highly infectious through inhalation route; for this reason it is used for biological warfare aims. This study aimed to ...

journal_title：Microbial pathogenesis

authors： Abadi AH,Mahdavi M,Khaledi A,Esmaeili SA,Esmaeili D,Sahebkar A

更新日期：2018-08-01 00:00:00

abstract：:Considered to be a potential "superbug", methicillin-resistant Staphylococcus aureus (MRSA) has been one of the major recent infectious pathogens and thus poses a challenge to hospital infection control. The mobile genetic element staphylococcal chromosomal cassette mec (SCCmec) carries both the mecA or mecC gene, enc...

journal_title：Microbial pathogenesis

authors： Liu J,Chen D,Peters BM,Li L,Li B,Xu Z,Shirliff ME

更新日期：2016-12-01 00:00:00

abstract：:Vibrio alginolyticus is a leading cause of vibriosis, presenting opportunistic infections to humans associated with raw seafood contamination. At present, phage therapy that acts as an alternative sanitizing agent is explored for targeting V. alginolyticus. The study outcome revealed that the phage VP01 with its extre...

journal_title：Microbial pathogenesis

authors： Sasikala D,Srinivasan P

更新日期：2016-12-01 00:00:00

abstract：:The biodegradation of Aflatoxin B1 (AFB1) is an industry of increasing importance. Bacillus licheniformis BL-010 was isolated from the aflatoxin contaminated corn feed storage, and was shown to degrade AFB1 efficiently. Here we present the complete genome sequence of BL-010, the genome comprises 4,287,714 bp in a circ...

journal_title：Microbial pathogenesis

authors： He S,Feng K,Ding T,Huang K,Yan H,Liu X,Zhang Z

更新日期：2018-05-01 00:00:00

abstract：:Recent studies have been considered to symbiotic interactions of the human gastrointestinal microbiota and human lifestyle-related disorders. The human gastrointestinal microbiota continuously stimulates the immune system against opportunistic and pathogen bacteria from infancy. Changes in gastrointestinal microbiota ...

journal_title：Microbial pathogenesis

authors： Gholizadeh P,Mahallei M,Pormohammad A,Varshochi M,Ganbarov K,Zeinalzadeh E,Yousefi B,Bastami M,Tanomand A,Mahmood SS,Yousefi M,Asgharzadeh M,Kafil HS

更新日期：2019-02-01 00:00:00

abstract：:Upon oxygen shift-down, Mycobacterium tuberculosis complex bacteria can induce a genetic program characterized by halted duplication, which is called Non-replicating persistence (NRP). During this phase, at least 48 genes, collectively named Dormancy survival regulator (DosR) regulon, are important for the long-term s...

journal_title：Microbial pathogenesis

authors： Jiménez BA,Hinojoza-Loza E,Flores-Valdez MA,Prado-Montes de Oca E,Allen K,Estrada-Chávez C,Herrera-Rodríguez S,Flores-Fernández JM,Martínez-Velázquez M,Hernández-Gutiérrez R,Alvarez AH

更新日期：2013-08-01 00:00:00

abstract：:Mycobacterium tuberculosis (MTB) the causative organism of tuberculosis can remain dormant as a non-culturable organism, reactivate and cause disease in man and animals. There is a need for proof of viability of such organisms in order to understand the process of reactivation. PCR for bacterial DNA cannot distinguish...

journal_title：Microbial pathogenesis

authors： Pai SR,Actor JK,Sepulveda E,Hunter RL Jr,Jagannath C

更新日期：2000-06-01 00:00:00

abstract：:The gene coding for serotype A of epidermolytic (exfoliative) toxin has been cloned from Staphylococcus aureus in Escherichia coli phage lambda and plasmid vectors. The coding sequence for eta was localised by subcloning and transposon Tn5 mutagenesis experiments. The eta gene was probably expressed from its natural p...

journal_title：Microbial pathogenesis

authors： O'Toole PW,Foster TJ

更新日期：1986-12-01 00:00:00

abstract：:A cytotoxin to Vero cells (Shiga-like toxin), which was neutralized by antibody against purified Shiga toxin produced by Shigella dysenteriae 1, was purified from Escherichia coli O157:H7, isolated from a patient with hemorrhagic colitis. The purification procedure consisted of ammonium sulfate fractionation, DEAE-cel...

journal_title：Microbial pathogenesis

authors： Noda M,Yutsudo T,Nakabayashi N,Hirayama T,Takeda Y

更新日期：1987-05-01 00:00:00

abstract：:In the present study, nine non-aflatoxigenic Aspergillus flavus strains were evaluated for their potential to reduce A. flavus infection and aflatoxin contamination in groundnut. Genetic characterization of these strains revealed six different deletion patterns (A-F) for thirteen examined genes from the aflatoxin bios...

journal_title：Microbial pathogenesis

authors： Hulikunte Mallikarjunaiah N,Jayapala N,Puttaswamy H,Siddapura Ramachandrappa N

更新日期：2017-01-01 00:00:00

abstract：:β-1,3-glucan plays a role in non-albicans Candida species biofilm formation and survival of biofilm Candida to stresses. In this study, we evaluated the antibiofilm activity of β-1,3-glucanase, which can degrade poly-β(1 → 3)-glucose of non-albicans Candida species biofilms, on single and mixed species biofilm of non-...

journal_title：Microbial pathogenesis

authors： Tan Y,Leonhard M,Ma S,Moser D,Schneider-Stickler B

更新日期：2017-12-01 00:00:00

abstract：:Two-component regulatory proteins, histidine kinases and response regulators, function in bacteria as sensing and adaptive factors in response to a wide range of environmental stimuli. Conserved histidine and glycine regions of histidine kinase sensor proteins were used to design degenerate oligonucleotide primers for...

journal_title：Microbial pathogenesis

authors： Haydel SE,Dunlap NE,Benjamin WH Jr

更新日期：1999-04-01 00:00:00

abstract：:Bean common mosaic virus (BCMV), the most common seed-borne pathogen in Phaseolus vulgaris L. is known to cause severe loss in productivity across the globe. In the present study, proteomic analyses were performed for leaf samples from control (healthy) and susceptible BCMV infected plants. The differential expression...

journal_title：Microbial pathogenesis

authors： Kumar S,Dhembla C,P H,Sundd M,Patel AK

更新日期：2020-01-01 00:00:00