Polymicrobial antibiofilm activity of the membranotropic peptide gH625 and its analogue.

abstract：:Brucellosis is a worldwide zoonotic infectious disease that has significant economic effects on animal production and human health. The host macrophage -Brucella interaction is critical to the establishment of infections. Thus, the kinetic transcriptional profile of gene expression in macrophages infected with the Bru...

journal_title：Microbial pathogenesis

authors： Liu Q,Han W,Sun C,Zhou L,Ma L,Lei L,Yan S,Liu S,Du C,Feng X

更新日期：2012-05-01 00:00:00

abstract：:A number of different techniques were used to analyse classic and atypical serogroup O:11 Aeromonas isolates. Five of seven atypical O:11, S layer-negative strains lacking a homogeneous LPS side-chain pattern exhibited varying degrees of mouse pathogenecity. One virulent atypical strain (AH-77) synthesized a surface a...

journal_title：Microbial pathogenesis

authors： Kokka RP,Vedros NA,Janda JM

更新日期：1991-01-01 00:00:00

abstract：:Chlamydia persistence is a viable but non-replicative stage, induced by several sub-lethal stressor agents, including beta-lactam antibiotics. So far, no data about the connection between doxycycline and chlamydial persistence has been described in literature. We investigated the ability of doxycycline to induce C. tr...

journal_title：Microbial pathogenesis

authors： Marangoni A,Zalambani C,Marziali G,Salvo M,Fato R,Foschi C,Re MC

更新日期：2020-10-01 00:00:00

abstract：:T lymphocyte-mediated immunity is important for resistance to Francisella tularensis. To characterize the specificity of this immunity, we used membrane proteins and two lipopolysaccharide (LPS) preparations. Both membrane proteins were heat-modifiable, as indicated by their migration in sodium dodecyl sulphate polyac...

journal_title：Microbial pathogenesis

authors： Surcel HM,Sarvas M,Helander IM,Herva E

更新日期：1989-12-01 00:00:00

abstract：:Corynebacterium pseudotuberculosis produces a sphingomyelin-specific phospholipase D exotoxin that is a major determinant in the pathogenesis of caseous lymphadenitis. We assessed the changes induced in the morphology and sphingomyelin concentration of ovine erythrocytes after incubation with broth culture filtrates o...

journal_title：Microbial pathogenesis

authors： Brogden KA,Engen RL,Songer JG,Gallagher J

更新日期：1990-02-01 00:00:00

abstract：:Salmonella serovars were examined for the presence of fim gene sequences using specific DNA probes. All strains, regardless of their ability to express surface-associated fimbriae, retain a considerable amount of DNA homologous to the gene probes used. The phenotypically nonfimbriae FIRN and non-FIRN strains of S. typ...

journal_title：Microbial pathogenesis

authors： Swenson DL,Clegg S,Old DC

更新日期：1991-06-01 00:00:00

abstract：:Binding of human enterotoxigenic Escherichia coli (ETEC) to the small intestine is a prerequisite for colonization and is mediated by colonization factor (CF) antigens. Coli surface antigen 6 (CS6) is considered a CF but binding to isolated enterocytes has not been established. In this study bacteria expressing CS6 we...

journal_title：Microbial pathogenesis

authors： Helander A,Hansson GC,Svennerholm AM

更新日期：1997-12-01 00:00:00

abstract：:Yersina enterocolitica-like species have not been extensively studied regarding its pathogenic potential. This work aimed to assess the pathogenic potential of some Y. enterocolitica-like strains by evaluating the presence of virulence-related genes by PCR and their ability to adhere to and invade Caco-2 and HEp-2 cel...

journal_title：Microbial pathogenesis

authors： Imori PF,Passaglia J,Souza RA,Rocha LB,Falcão JP

更新日期：2017-03-01 00:00:00

abstract：:Host cell invasion is important for periodontal pathogens in evading host defenses and spreading into deeper areas of the periodontal tissue. Treponema denticola has been implicated in a number of potentially pathogenic processes, including periodontal tissue penetration. Here we tested the ability of T. denticola str...

journal_title：Microbial pathogenesis

authors： Inagaki S,Kimizuka R,Kokubu E,Saito A,Ishihara K

更新日期：2016-05-01 00:00:00

abstract：:Genital serovariants of Chlamydia trachomatis establish infection by attachment, entry and multiplication within human endometrial epithelial cells. In previous studies, a chlamydial recombinant Escherichia coli was identified which exhibited a specific adherent phenotype to endometrial epithelial cells closely resemb...

journal_title：Microbial pathogenesis

authors： Schmiel DH,Raulston JE,Fox E,Wyrick PB

更新日期：1995-10-01 00:00:00

abstract：:Pneumocystis infection leads to a life threatening pneumonia in susceptible individuals. While depletion or dysfunction of CD4+T cells is a key determinant of susceptibility to Pneumocystis, the host response that leads to resolution of infection or lung injury is less well understood. We had previously shown that mic...

journal_title：Microbial pathogenesis

authors： Rose CM,Kimzey SL,Green JM

更新日期：2006-01-01 00:00:00

abstract：:The antimicrobial properties of morel compounds from wild edible mushrooms (Morchella esculenta and Verpa bohemica) from Kashmir valley was investigated against different clinical pathogens. The butanol crude fraction of most popular or true morel M. esculenta showed highest 19 mm IZD against E.coli while as same frac...

journal_title：Microbial pathogenesis

authors： Shameem N,Kamili AN,Ahmad M,Masoodi FA,Parray JA

更新日期：2017-04-01 00:00:00

abstract：:The hemA mutation reduces the virulence of Salmonella typhimurium for mice by at least 10(7)-fold, as measured by change in LD50. The hemA mutation does not appear to affect killing of salmonella in mice. The salmonella with the hemA mutation persist in the spleen and liver for 2 to 3 weeks following intravenous injec...

journal_title：Microbial pathogenesis

authors： Benjamin WH Jr,Hall P,Briles DE

更新日期：1991-10-01 00:00:00

abstract：:In the present study, we isolated Lactobacillus sakei strain DGH5 from raw beef meat. This bacterium plays an inhibitory effect against food-spoiling bacteria and food-borne pathogens, including Listeria monocytogenes, a gram-positive and pathogenic bacterium. Lactobacillus sakei strain DGH5 was identified through bot...

journal_title：Microbial pathogenesis

authors： Tashakor A,Hosseinzadehdehkordi M,Emruzi Z,Gholami D

更新日期：2017-05-01 00:00:00

abstract：:In this study we generated and characterized a series of monoclonal antibodies (mAbs) against GII.6 norovirus (NoV) virus like particles (VLPs). Mice were immunized with purified GII.6 NoV VLPs and peptide-bovine serum albumin (BSA) conjugates with the peptide sequence (31 aa) derived from the trypsin cleavage region....

journal_title：Microbial pathogenesis

authors： Qiu S,Zheng L,Qin C,Yin X,Ma J,Liu J,Yang Z,Li C,Wang Y,Wang M,Qi Y,Huo Y

更新日期：2020-02-26 00:00:00

abstract：:Candida albicans yeast cells bind soluble human plasma fibronectin (Fn) through a glycoprotein receptor (adhesin) located on the cell surface. This work demonstrates that a 120 kDa proteolytic fragment of Fn encompassing the cell binding domain binds more avidly to the yeast cell adhesin than does the parent Fn molecu...

journal_title：Microbial pathogenesis

authors： Penn C,Klotz SA

更新日期：1994-12-01 00:00:00

abstract：:Helicobacter pylori (H. pylori) usually colonizes the gastric mucosa of more than 50% of the human population, causing an infection that may appear in early childhood and can persist for life. H. pylori is suggested as the main cause of peptic ulcer and chronic gastritis. It is also associated with gastric cancer. Its...

journal_title：Microbial pathogenesis

authors： Bagheri N,Azadegan-Dehkordi F,Rafieian-Kopaei M,Rahimian G,Asadi-Samani M,Shirzad H

更新日期：2016-11-01 00:00:00

abstract：:As a stationary-phase signal, indole is secreted in large quantities by Escherichia coli on enriched media and has been shown to control several genes; however, its impact on acid resistance remains to be studied in detail. Real-time quantitative reverse transcription-polymerase chain reaction analysis revealed that i...

journal_title：Microbial pathogenesis

authors： Hirakawa H,Hayashi-Nishino M,Yamaguchi A,Nishino K

更新日期：2010-09-01 00:00:00

abstract：:The emergence of extensively drug-resistant (XDR) Acinetobacter baumannii strains and the limited number of efficacious antibiotics demonstrate an urgent need to develop novel agents to treat infections caused by this dangerous pathogen. To find antimicrobial peptides against A. baumannii growing either in planktonic ...

journal_title：Microbial pathogenesis

authors： Irani N,Basardeh E,Samiee F,Fateh A,Shooraj F,Rahimi A,Shahcheraghi F,Vaziri F,Masoumi M,Pazhouhandeh M,Siadat SD,Kazemi-Lomedasht F,Jamnani FR

更新日期：2018-08-01 00:00:00

abstract：:Vibrio parahaemolyticus is a leading cause of seafood-associated bacterial gastroenteritis. The pathogen produces the thermostable direct hemolysin (TDH), which is the sole cause of the Kanagawa phenomenon (KP), a special β-type haemolysis in the Wagatsuma agar. TDH also exerts several other biological activities, the...

journal_title：Microbial pathogenesis

authors： Cai Q,Zhang Y

更新日期：2018-10-01 00:00:00

abstract：:Upon oxygen shift-down, Mycobacterium tuberculosis complex bacteria can induce a genetic program characterized by halted duplication, which is called Non-replicating persistence (NRP). During this phase, at least 48 genes, collectively named Dormancy survival regulator (DosR) regulon, are important for the long-term s...

journal_title：Microbial pathogenesis

authors： Jiménez BA,Hinojoza-Loza E,Flores-Valdez MA,Prado-Montes de Oca E,Allen K,Estrada-Chávez C,Herrera-Rodríguez S,Flores-Fernández JM,Martínez-Velázquez M,Hernández-Gutiérrez R,Alvarez AH

更新日期：2013-08-01 00:00:00

abstract：:HTLV-1 infects principally CD4+ T cells that are the main reservoirs of the virus in vivo, which play an important role in the immunological response. Most of the infected patients are asymptomatic. However, 2-3% of patients will develop HAM/TSP or Adult T lymphoma. HAM/TSP is a chronic inflammatory disease of the cen...

journal_title：Microbial pathogenesis

authors： da Silva Dias GA,Sousa RCM,Gomes LF,Caldas CAM,Nassiri R,Quaresma JAS,Fuzii HT

更新日期：2016-03-01 00:00:00

abstract：:As a typical Gram-positive microorganism, S. aureus was recognized as common foodborne pathogenic bacteria in food industry. To study their individuality and pathogenicity mechanism, thirty-three Staphylococci strains were applied to the investigation with the identification of MRSA by PCR targeting on S. aureus speci...

journal_title：Microbial pathogenesis

authors： Miao J,Wang W,Xu W,Su J,Li L,Li B,Zhang X,Xu Z

更新日期：2018-12-01 00:00:00

abstract：:An inbred strain of the southern platyfish, Xiphophorus maculatus, was used as a host for Aeromonas hydrophila and Yersinia ruckeri infections. The infections were initiated by holding the platyfish in inoculation baths containing dilutions of virulent A. hydrophila or Y. ruckeri strains. Inoculating the platyfish in ...

journal_title：Microbial pathogenesis

authors： Kawula TH,Lelivelt MJ,Orndorff PE

更新日期：1996-02-01 00:00:00

abstract：:In this paper, we have assessed the role of changing physicochemical parameters and substrate types on the production of α-amylase enzyme from Penicillium chrysogenum, with a view to determining the optimal conditions required for its maximum production. The findings of this research revealed that, at pH 6 using linse...

journal_title：Microbial pathogenesis

authors： Dar GH,Kamili AN,Nazir R,Bandh SA,Jan TR,Chishti MZ

更新日期：2015-11-01 00:00:00

abstract：:Invasion plasmid antigen C (IpaC) is secreted by the Shigella flexneri type III secretion system (TTSS) as an essential trigger of epithelial cell invasion. At the molecular level, IpaC possesses a distinct functional organization. The IpaC C-terminal region between amino acids 319 and 345 is predicted to form a coile...

journal_title：Microbial pathogenesis

authors： Terry CM,Picking WL,Birket SE,Flentie K,Hoffman BM,Barker JR,Picking WD

更新日期：2008-10-01 00:00:00

abstract：:Chlamydia pneumoniae is associated with several chronic human diseases, including chronic obstructive pulmonary disease and atherosclerotic cardiovascular disease. During chronic disease, organisms are believed to exist in a persistent phase that is not well understood at the genetic level. Long-term in vitro continuo...

journal_title：Microbial pathogenesis

authors： Hogan RJ,Mathews SA,Kutlin A,Hammerschlag MR,Timms P

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Since the high morbidity and mortality of candidemia among cancer patients, the epidemiology has been underlined. In recent years, Candida species genotyping has been established, which could provide detail characteristics of epidemiology and has been underscored for candidemia preventing strategies. METHOD...

journal_title：Microbial pathogenesis

authors： Li D,Li X,Xia R,Zhang W,Zheng S,Zhang Q,Bai C,Zhang P

更新日期：2015-04-01 00:00:00

abstract：:To assess the role of mannosylated lipoarabinomannan (ManLAM) in the inflammatory and apoptotic response of mycobacteria-infected and uninfected, bystander cells we applied a mouse macrophage model of infection with avirulent strains--Mycobacterium bovis BCG, Mycobacterium tuberculosis (MTB) H37Ra and compared with a ...

journal_title：Microbial pathogenesis

authors： Wojtas B,Fijalkowska B,Wlodarczyk A,Schollenberger A,Niemialtowski M,Hamasur B,Pawlowski A,Krzyzowska M

更新日期：2011-07-01 00:00:00

abstract：:Intravenous inoculation of Swiss mice with S. aureus leads to severe synovial joint tissue swelling along with prominent T lymphocyte infiltrate with associated inflammation in synovial tissue. Cytokines released from macrophages such as TNF-α, IL-1β and IL-6 the main players that precede cartilage and bone destructio...

journal_title：Microbial pathogenesis

authors： Dey I,Bishayi B

更新日期：2017-12-01 00:00:00