Abstract:
:Vibrio alginolyticus is a leading cause of vibriosis, presenting opportunistic infections to humans associated with raw seafood contamination. At present, phage therapy that acts as an alternative sanitizing agent is explored for targeting V. alginolyticus. The study outcome revealed that the phage VP01 with its extreme lytic effect showed a high potential impact on the growth of V. alginolyticus as well as biofilm formation. Electron microscopy revealed the phage resemblance to Myoviridae, based on its morphology. Further study clarified that the phage VP01 possesses a broad host spectrum and amazing phage sensitivity at different pH, high thermal stability, and high burst size of 415 PFU/cell. In addition, the investigation of phage co-culturing against this pathogen resulted in a significant growth reduction even at less MOIs 0.1 and 1. These results suggest that the phage could be a promising candidate for the control of V. alginolyticus infections.
journal_name
Microb Pathogjournal_title
Microbial pathogenesisauthors
Sasikala D,Srinivasan Pdoi
10.1016/j.micpath.2016.10.017subject
Has Abstractpub_date
2016-12-01 00:00:00pages
24-35eissn
0882-4010issn
1096-1208pii
S0882-4010(16)30345-Xjournal_volume
101pub_type
杂志文章abstract::The live oral typhoid vaccine Ty21a has proved to confer protection against the disease at least as effectively as killed parenteral vaccines, whereas killed oral vaccines have not been protective in field trials. This prompted us to compare the immune response of subjects vaccinated either with live oral, killed oral...
journal_title:Microbial pathogenesis
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doi:10.1016/j.micpath.2008.08.005
更新日期:2008-11-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.micpath.2016.05.018
更新日期:2016-08-01 00:00:00
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journal_title:Microbial pathogenesis
pub_type: 杂志文章
doi:10.1016/j.micpath.2018.01.013
更新日期:2018-03-01 00:00:00
abstract::We previously demonstrated that incubation of E. coli in normal human serum (NHS) resulted in the release of a finite fraction (approximately 30%) of LPS from the bacterial outer membrane. In experiments reported here, we examined factors which may enhance or diminish the capacity of NHS to mediate this limited LPS re...
journal_title:Microbial pathogenesis
pub_type: 杂志文章
doi:10.1016/0882-4010(88)90068-x
更新日期:1988-03-01 00:00:00
abstract::Edwardsiella piscicida is a Gram-negative pathogen that causes disease in diverse aquatic organisms. The disease leads to extensive losses in commercial aquaculture species, including farmed U.S. catfish. The type III secretion system (T3SS) often contributes to virulence of Gram-negative bacteria. The E. piscicida es...
journal_title:Microbial pathogenesis
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doi:10.1016/j.micpath.2020.104108
更新日期:2020-06-01 00:00:00
abstract::The high incidence of bacterial respiratory infections has led to a focus on evaluating the human respiratory microbiome. Studies based on culture-based and molecular methods have shown an increase in the bacterial community that includes the bacterial phyla Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteri...
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pub_type: 杂志文章
doi:10.1016/j.micpath.2020.104115
更新日期:2020-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.micpath.2017.04.039
更新日期:2017-07-01 00:00:00
abstract::β-1,3-glucan plays a role in non-albicans Candida species biofilm formation and survival of biofilm Candida to stresses. In this study, we evaluated the antibiofilm activity of β-1,3-glucanase, which can degrade poly-β(1 → 3)-glucose of non-albicans Candida species biofilms, on single and mixed species biofilm of non-...
journal_title:Microbial pathogenesis
pub_type: 杂志文章
doi:10.1016/j.micpath.2017.10.057
更新日期:2017-12-01 00:00:00
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doi:10.1016/j.micpath.2021.104748
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doi:10.1006/mpat.2001.0460
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pub_type: 杂志文章
doi:10.1016/0882-4010(90)90048-u
更新日期:1990-03-01 00:00:00
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journal_title:Microbial pathogenesis
pub_type: 杂志文章
doi:10.1016/j.micpath.2016.08.031
更新日期:2016-10-01 00:00:00
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journal_title:Microbial pathogenesis
pub_type: 杂志文章
doi:10.1016/0882-4010(92)90112-2
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journal_title:Microbial pathogenesis
pub_type: 杂志文章
doi:10.1016/j.micpath.2013.04.013
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journal_title:Microbial pathogenesis
pub_type: 杂志文章,评审
doi:10.1016/s0882-4010(03)00099-8
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Blastocystis is one of the most common pathogens of the human intestine, caused by an emerging parasite, which can lead to severe symptoms and even death in immunocompromised patients. We aimed to determine the global prevalence of Blastocystosis infection in people with immunodeficiency. A systematic litera...
journal_title:Microbial pathogenesis
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doi:10.1016/j.micpath.2020.104615
更新日期:2020-11-24 00:00:00
abstract::The gene gseA, involved in the expression of the genus-specific epitope of chlamydial lipopolysaccharide (LPS), was analyzed by temperature gradient gel electrophoresis (TGGE) to visualize nucleotide sequence variations among the 15 serovars of Chlamydia trachomatis. Sequence analysis showed that the TGGE melting-prof...
journal_title:Microbial pathogenesis
pub_type: 杂志文章
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更新日期:1994-08-01 00:00:00
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journal_title:Microbial pathogenesis
pub_type: 杂志文章
doi:10.1016/j.micpath.2010.02.007
更新日期:2010-05-01 00:00:00
abstract::The focus of this study was the phenotypic characterization of Salmonella typhimurium mutants lacking the function of the response regulator mviA. The inactivation of mviA+ (mviA::kan) is shown to induce a significant change in the growth of most virulent strains, as reflected in the size of the colonies formed on aga...
journal_title:Microbial pathogenesis
pub_type: 杂志文章
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更新日期:1997-06-01 00:00:00