The ability of CpG oligonucleotides to protect mice against Francisella tularensis live vaccine strain but not fully virulent F. tularensis subspecies holarctica is reflected in cell-based assays.

abstract：:E. coli infections in avian species have become an economic threat to the poultry industry worldwide. Several factors have been associated with the virulence of E. coli in avian hosts, but no specific virulence gene has been identified as being entirely responsible for the pathogenicity of avian pathogenic E. coli (AP...

journal_title：Microbial pathogenesis

authors： Antão EM,Glodde S,Li G,Sharifi R,Homeier T,Laturnus C,Diehl I,Bethe A,Philipp HC,Preisinger R,Wieler LH,Ewers C

更新日期：2008-11-01 00:00:00

abstract：:The growth inhibitory effects of chicken egg white ovomacroglobulin (ovoM) on Serratia marcescens and Pseudomonas aeruginosa were studied. The growth of protease-producing strains was greater than that of the strains producing little protease, and was inhibited in a dose-dependent manner by ovoM, a potent protease inh...

journal_title：Microbial pathogenesis

authors： Miyagawa S,Nishino N,Kamata R,Okamura R,Maeda H

更新日期：1991-08-01 00:00:00

abstract：:The ica operon and aap gene are important factors for Staphylococcus epidermidis biofilm formation. However, we found 15 out of 101 S. epidermidis strains isolated from patients had both the ica operon and the aap gene in the genome but could not form biofilms (ica(+)aap(+)/BF(-) isolates). Compared with standard stra...

journal_title：Microbial pathogenesis

authors： Wu Y,Liu J,Jiang J,Hu J,Xu T,Wang J,Qu D

更新日期：2014-11-01 00:00:00

abstract：:Bovine leukemia virus (BLV) is transcriptionally silent in most circulating peripheral blood mononuclear cells (PBMCs) of animals with well-established infections. Using PBMCs from a newly infected sheep, we asked whether viral transcription proceeded differently during the initial months of infection, when the preval...

journal_title：Microbial pathogenesis

authors： Radke K,Sigala TJ,Grossman D

更新日期：1992-05-01 00:00:00

abstract：:In this study an attempt to address the effects of immunosuppression on pathogenesis of peste des petits ruminants (PPR) virus infection was undertaken. Cyclophosphamide and dexamethasone were used to immunosuppress the animals. The drug treated animals exhibited severe leukopaenia and lymphopaenia; one of the indicat...

journal_title：Microbial pathogenesis

authors： Jagtap SP,Rajak KK,Garg UK,Sen A,Bhanuprakash V,Sudhakar SB,Balamurugan V,Patel A,Ahuja A,Singh RK,Vanamayya PR

更新日期：2012-04-01 00:00:00

abstract：:Porphyromonas gingivalis is highly implicated in the pathogenesis of periodontitis, which is characterized by the destruction of periodontal connective tissues and the supporting alveolar bone. Receptor Activator of NF-kappaB Ligand (RANKL) stimulates bone resorption, whereas osteoprotegerin (OPG) blocks its action, a...

journal_title：Microbial pathogenesis

authors： Belibasakis GN,Bostanci N,Hashim A,Johansson A,Aduse-Opoku J,Curtis MA,Hughes FJ

更新日期：2007-07-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is a common cause of hospital-acquired infection and has become an epidemic globally. Alpha-haemolysin (α-haemolysin), a pore-forming toxin, is one of the most important virulence factors secreted by most S. aureus strains. α-haemolysin monomers form a 232.4-kDa membrane-inserted hept...

journal_title：Microbial pathogenesis

authors： Zhou Y,Chen C,Pan J,Deng X,Wang J

更新日期：2018-02-01 00:00:00

abstract：:The study was conducted to examine the antioxidant enzymes induced by Trichoderma viride JAU60 as initial defense response during invasion of rot pathogen Aspergillus niger Van Tieghem in five groundnut varieties under pot culture. Seed treatment of T. viride JAU60 reduced 51-58% collar rot disease incidence in differ...

journal_title：Microbial pathogenesis

authors： Gajera HP,Katakpara ZA,Patel SV,Golakiya BA

更新日期：2016-02-01 00:00:00

abstract：:Lack of a system for genetic manipulation of Chlamydia trachomatis has been a key challenge to advancing understanding the molecular genetic basis of virulence for this bacterial pathogen. We developed a non-viral, dendrimer-enabled system for transformation of this organism and used it to characterize the effects of ...

journal_title：Microbial pathogenesis

authors： Kannan RM,Gérard HC,Mishra MK,Mao G,Wang S,Hali M,Whittum-Hudson JA,Hudson AP

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) remains a major public health problem. SH3RF1 and SH3RF2 are candidate genes with multiple single-nucleotide polymorphisms (SNPs) that have the potential to participate in Mycobacterium infection via activation of the JNK signaling pathway. In this case-control study, we aimed to investigat...

journal_title：Microbial pathogenesis

authors： Chen H,Zhou J,Jiao L,Song J,Zhong H,Zhao Z,Meng Z,Lu X,Chen X,Zhang W,Ying B

更新日期：2020-10-28 00:00:00

abstract：:Attenuated recombinant Listeria monocytogenes (Lm) strains are a promising class of vaccine vectors that trigger protective antigen-specific CD8 T cells. Listeriolysin O (LLO) is an important Lm virulence determinant allowing the bacterium to escape from the endocytic vacuole into the cell cytoplasm in phagocytic cell...

journal_title：Microbial pathogenesis

authors： Orgun NN,Way SS

更新日期：2008-02-01 00:00:00

abstract：:Klebsiella pneumoniae is one of the most important agents of community-acquired urinary tract infection (CA-UTI). In addition to extended-spectrum β-lactamases (ESBLs), a number of virulence factors have been shown to play an important role in the pathogenesis of K. pneumoniae, including capsule, siderophores, and adh...

journal_title：Microbial pathogenesis

authors： Ranjbar R,Memariani H,Sorouri R,Memariani M

更新日期：2016-11-01 00:00:00

abstract：:Microglial inflammation is the hallmark of S. aureus induced brain abscesses. Conventional antibiotic therapy could not regulate inflammation and the use of steroids in CNS infection remained controversial. To address this issue the effect of dexamethasone along with ciprofloxacin on microglial inflammation has been a...

journal_title：Microbial pathogenesis

authors： Dey R,Bishayi B

更新日期：2020-08-01 00:00:00

abstract：:This study aimed to isolate and demonstrate their antioxidant and immunostimulatory activities of potential probiotics. The isolated strains, S. Pum19, SC28, and SC61 showed potential probiotic properties including stability in artificial gastric and bile conditions, non-production of β-glucuronidase, suitable antibio...

journal_title：Microbial pathogenesis

authors： Son SH,Yang SJ,Jeon HL,Yu HS,Lee NK,Park YS,Paik HD

更新日期：2018-12-01 00:00:00

abstract：:Corynebacterium pseudotuberculosis produces a sphingomyelin-specific phospholipase D exotoxin that is a major determinant in the pathogenesis of caseous lymphadenitis. We assessed the changes induced in the morphology and sphingomyelin concentration of ovine erythrocytes after incubation with broth culture filtrates o...

journal_title：Microbial pathogenesis

authors： Brogden KA,Engen RL,Songer JG,Gallagher J

更新日期：1990-02-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...

journal_title：Microbial pathogenesis

authors： Heng Y,Mao W,Yong M,Yang G,Su Q,Wang J

更新日期：2018-08-08 00:00:00

abstract：:The macrophage innate immune response is outlined through recognition of the components of Mycobacterium tuberculosis. DNA of M. tuberculosis (MtbDNA) is recognized by macrophages, but the implications of this recognition are poorly characterized. Stimulation of murine macrophages with MtbDNA induces autophagy, a proc...

journal_title：Microbial pathogenesis

authors： Ruiz A,Guzmán-Beltrán S,Carreto-Binaghi LE,Gonzalez Y,Juárez E

更新日期：2019-07-01 00:00:00

abstract：:The live oral typhoid vaccine Ty21a has proved to confer protection against the disease at least as effectively as killed parenteral vaccines, whereas killed oral vaccines have not been protective in field trials. This prompted us to compare the immune response of subjects vaccinated either with live oral, killed oral...

journal_title：Microbial pathogenesis

authors： Kantele A,Arvilommi H,Kantele JM,Rintala L,Mäkelä PH

更新日期：1991-02-01 00:00:00

abstract：:Adhesion is the first step for Candida species to form biofilms on medical devices implanted in the human host. Both the physicochemical nature of the biomaterial and cell wall proteins (CWP) of the pathogen play a determinant role in the process. While it is true that some CWP have been identified in vitro, little is...

journal_title：Microbial pathogenesis

authors： Núñez-Beltrán A,López-Romero E,Cuéllar-Cruz M

更新日期：2017-06-01 00:00:00

abstract：:Toxoplasma gondii is an obligate intracellular parasite that is globally distributed and can infect almost all warm-blooded animals, including humans. While vaccines are not available for prophylaxis, there are limited therapeutic options which often do not result in eradication of parasites from patients. ME49 is a c...

journal_title：Microbial pathogenesis

authors： Ma Z,Mutashar Alhameed AM,Kaminga AC,Lu B,Li X,Zhang J,Wu X

更新日期：2020-03-01 00:00:00

abstract：:Because of the close genetic relatedness between apes and humans, apes are susceptible to many human infectious agents and can serve as carriers of these pathogens. Consequently, they present a serious health hazard to humans. Moreover, many emerging infectious diseases originate in wildlife and continue to threaten h...

journal_title：Microbial pathogenesis

authors： Keita MB,Hamad I,Bittar F

更新日期：2014-12-01 00:00:00

abstract：:The bacterial cell communication also termed as Quorum sensing (QS) system was involved in the expression of several virulence traits during Pseudomonas infection. The attenuating of this bacterial cell communication system is an attractive approach for the management of bacterial infections without the complication o...

journal_title：Microbial pathogenesis

authors： Parasuraman P,Devadatha B,Sarma VV,Ranganathan S,Ampasala DR,Siddhardha B

更新日期：2020-01-01 00:00:00

abstract：:It has been shown that N-linked high mannose type oligosaccharides competitively inhibits attachment to and infectivity of chlamydiae in HeLa cells. To further study whether mannose moieties are involved in the infectivity of chlamydiae, the susceptibility of mannose-receptor negative J774A and positive J774E mouse ma...

journal_title：Microbial pathogenesis

authors： Kuo CC,Puolakkainen M,Lin TM,Witte M,Campbell LA

更新日期：2002-01-01 00:00:00

abstract：:Visfatin plays an important role in regulation of inflammatory cytokines. However, the role of visfatin under bacterial stress condition is not fully explored yet. Therefore, the present study was conducted for the better understanding of the regulation mechanism of visfatin on the production of inflammatory cytokines...

journal_title：Microbial pathogenesis

authors： Wu XT,Yang Z,Ansari AR,Xiao K,Pang XX,Luo Y,Song H

更新日期：2018-04-01 00:00:00

abstract：:Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are two major omega-3 polyunsaturated fatty acids (n-3 PUFAs) with antimicrobial properties. In this study, we evaluated the potential antibacterial and antibiofilm activities of DHA and EPA against two periodontal pathogens, Porphyromonas gingivalis (P. gingi...

journal_title：Microbial pathogenesis

authors： Sun M,Zhou Z,Dong J,Zhang J,Xia Y,Shu R

更新日期：2016-10-01 00:00:00

abstract：:The gene coding for serotype A of epidermolytic (exfoliative) toxin has been cloned from Staphylococcus aureus in Escherichia coli phage lambda and plasmid vectors. The coding sequence for eta was localised by subcloning and transposon Tn5 mutagenesis experiments. The eta gene was probably expressed from its natural p...

journal_title：Microbial pathogenesis

authors： O'Toole PW,Foster TJ

更新日期：1986-12-01 00:00:00

abstract：:Pasteurella multocida capsular type A can cause a pulmonary infection, leading to serious pecuniary losses in cattle. The heterogeneity of infection outcome of P. multocida strains showing different virulence may be related to divergent expression of virulence genes. In this study, we compared the transcriptional resp...

journal_title：Microbial pathogenesis

authors： Cheng Y,Wang K,Lin L,Zhao X,Pan Z,Zhou Z

更新日期：2020-03-01 00:00:00

abstract：:Xanthene derivatives are well known for their effective biological activities. In search of effective antibacterial agents, the spiro[indoline3,9-xanthene]-trione (A) and hydroxy-spiro[indoline-3,9-xanthene]-trione (B), were synthesized and tested for in vitro antibacterial activity against Staphylococcus aureus and E...

journal_title：Microbial pathogenesis

authors： Barmak A,Niknam K,Mohebbi G,Pournabi H

更新日期：2019-05-01 00:00:00

abstract：:Mycobacterium avium complex (MAC) strains from AIDS and non-AIDS patients and from the environment were studied for their colony morphology and virulence in beige mice. The majority of the MAC isolates from AIDS patients, in contrast to those from non-AIDS patients and the environment, showed increased virulence. Simi...

journal_title：Microbial pathogenesis

authors： Reddy VM,Parikh K,Luna-Herrera J,Falkinham JO 3rd,Brown S,Gangadharam PR

更新日期：1994-02-01 00:00:00

abstract：:Fast emerging antibiotic resistance in pathogens requires special attention for strengthening the reservoir of antimicrobial compounds. In view of this, several peptides with known antimicrobial activities have been reported to enhance the efficacy of antibiotics against multidrug resistant (MDR) pathogens. In the pre...

journal_title：Microbial pathogenesis

authors： Rishi P,Vij S,Maurya IK,Kaur UJ,Bharati S,Tewari R

更新日期：2018-11-01 00:00:00