当前位置： SCI文献检索 > MICROBIAL PATHOGENESIS期刊下所有文献 > Distribution of virulence genes and genotyping of CTX-M-15-producing Klebsiella pneumoniae isolated from patients with community-acquired urinary tract infection (CA-UTI).

Distribution of virulence genes and genotyping of CTX-M-15-producing Klebsiella pneumoniae isolated from patients with community-acquired urinary tract infection (CA-UTI).

Abstract：

:Klebsiella pneumoniae is one of the most important agents of community-acquired urinary tract infection (CA-UTI). In addition to extended-spectrum β-lactamases (ESBLs), a number of virulence factors have been shown to play an important role in the pathogenesis of K. pneumoniae, including capsule, siderophores, and adhesins. Little is known about the genetic diversity and virulence content of the CTX-M-15-producing K. pneumoniae isolated from CA-UTI in Iran. A total of 152 K. pneumoniae isolates were collected from CA-UTI patients in Tehran from September 2015 through April 2016. Out of 152 isolates, 40 (26.3%) carried blaCTX-M-15. PCR was performed for detection of virulence genes in CTX-M-15-producing isolates. Furthermore, all of these isolates were subjected to multiple-locus variable-number of tandem repeat (VNTR) analysis (MLVA). Using MLVA method, 36 types were identified. CTX-M-15-producing K. pneumoniae isolates were grouped into 5 clonal complexes (CCs). Of these isolates, mrkD was the most prevalent virulence gene (95%), followed by kpn (60%), rmpA (37.5%), irp (35%), and magA (2.5%). No correlation between MLVA types or CCs and virulence genes or antibiotic resistance patterns was observed. Overall, it is thought that CTX-M-15-producing K. pneumoniae strains isolated from CA-UTI have arisen from different clones.

journal_name

Microb Pathog

journal_title

Microbial pathogenesis

authors

Ranjbar R,Memariani H,Sorouri R,Memariani M

doi

10.1016/j.micpath.2016.10.002

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

244-249

eissn

0882-4010

issn

1096-1208

pii

S0882-4010(16)30412-0

journal_volume

100

pub_type

杂志文章

相关文献

MICROBIAL PATHOGENESIS文献大全
  • Phosphoglycerate kinase inhibits epithelial cell invasion by group B streptococci.

    abstract：:Group B streptococci (GBS) are opportunistic human pathogens that cause infection and invasive disease in newborns, pregnant women and non-pregnant adults. The internalization of GBS into eukaryotic cells occurs in an actin-microfilament dependent process. The objective of our study was to understand what host cell an...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2005.02.002

    authors： Burnham CA,Shokoples SE,Tyrrell GJ

    更新日期：2005-05-01 00:00:00

  • Laying hens fed mycotoxin-contaminated feed produced by Fusarium fungi (T-2 toxin and fumonisin B1) and Saccharomyces cerevisiae lysate: Impacts on poultry health, productive efficiency, and egg quality.

    abstract：:Mycotoxins represent substantial challenges to the farming industry. These include toxins produced by Fusarium fungi, particularly trichothecenes (toxin T-2) and fumonisin (FB1). In the present study, we determined the effects of addition on Saccharomyces cerevisiae lysate (SCL) added to feed contaminated with T-2 and...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2020.104517

    authors： Dazuk V,Boiago MM,Rolim G,Paravisi A,Copetti PM,Bissacotti BF,Morsch VM,Vedovatto M,Gazoni FL,Matte F,Gloria EM,Da Silva AS

    更新日期：2020-12-01 00:00:00

  • Difference of genotypic and phenotypic characteristics and pathogenicity potential of Photobacterium damselae subsp. damselae between clinical and environmental isolates from Japan.

    abstract：:Photobacterium damselae subsp. damselae has been known as an opportunistic pathogen in fish and mammals. Human infectious cases are often very serious and occasionally fatal. We previously reportedtwo fatal cases caused by this subspecies where the patients developed multiple organ failure within 20-36 h after the ons...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2008.04.008

    authors： Takahashi H,Miya S,Kimura B,Yamane K,Arakawa Y,Fujii T

    更新日期：2008-08-01 00:00:00

  • Comparison of the human immune response to live oral, killed oral or killed parenteral Salmonella typhi TY21A vaccines.

    abstract：:The live oral typhoid vaccine Ty21a has proved to confer protection against the disease at least as effectively as killed parenteral vaccines, whereas killed oral vaccines have not been protective in field trials. This prompted us to compare the immune response of subjects vaccinated either with live oral, killed oral...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/0882-4010(91)90072-i

    authors： Kantele A,Arvilommi H,Kantele JM,Rintala L,Mäkelä PH

    更新日期：1991-02-01 00:00:00

  • Transcript analysis of nrrF, a Fur repressed sRNA of Neisseria gonorrhoeae.

    abstract：:Like most microorganisms, Neisseria gonorrhoeae alters gene expression in response to iron availability. The ferric uptake regulator Fur has been shown to be involved in controlling this response, but the extent of this involvement remains unknown. It is known that in addition to working directly to repress gene expre...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2008.12.003

    authors： Ducey TF,Jackson L,Orvis J,Dyer DW

    更新日期：2009-03-01 00:00:00

  • Fecal bacteria from Crohn's disease patients more potently activated NOD-like receptors and Toll-like receptors in macrophages, in an IL-4-repressible fashion.

    abstract：:Crohn's disease (CD) is characterized by a pathogenic intestinal inflammation mediated by a Th1-skewed immune system and a dysregulated intestinal mucosal community. In this study, we investigated the role of bacteria on the activation and function of monocytes, and its association with CD pathogenesis. To this end, f...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2018.05.009

    authors： Gu J,Liu G,Xing J,Song H,Wang Z

    更新日期：2018-08-01 00:00:00

  • High-resolution melting-curve (HRM) analysis for C. meleagridis identification in stool samples.

    abstract：BACKGROUND:Cryptosporidiosis represents a major public health problem. This infection, caused by a protozoan parasite of the genus Cryptosporidium, has been reported worldwide as a frequent cause of diarrhoea. In the immunocompetent host, the typical watery diarrhea can be self-limiting. However, it is severe and chron...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2017.12.070

    authors： Chelbi H,Essid R,Jelassi R,Bouzekri N,Zidi I,Ben Salah H,Mrad I,Ben Sghaier I,Abdelmalek R,Aissa S,Bouratbine A,Aoun K

    更新日期：2018-02-01 00:00:00

  • A hemA mutation renders Salmonella typhimurium avirulent in mice, yet capable of eliciting protection against intravenous infection with S. typhimurium.

    abstract：:The hemA mutation reduces the virulence of Salmonella typhimurium for mice by at least 10(7)-fold, as measured by change in LD50. The hemA mutation does not appear to affect killing of salmonella in mice. The salmonella with the hemA mutation persist in the spleen and liver for 2 to 3 weeks following intravenous injec...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/0882-4010(91)90033-7

    authors： Benjamin WH Jr,Hall P,Briles DE

    更新日期：1991-10-01 00:00:00

  • Influence of a 70 kilobase virulence plasmid on the ability of Yersinia enterocolitica to survive phagocytosis in vitro.

    abstract：:During the course of infection, Yersinia enterocolitica invades tissues where macrophages and polymorphonuclear leucocytes (PMNs) constitute the first line of defence. As expression of virulence in Y. enterocolitica is governed in part by a c. 70 kilobase virulence plasmid (pYV), we investigated the influence of this ...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/0882-4010(92)90018-j

    authors： Tabrizi SN,Robins-Browne RM

    更新日期：1992-09-01 00:00:00

  • Molecular-genetic peculiarities of classical biotype Vibrio cholerae, the etiological agent of the last outbreak Asiatic cholera in Russia.

    abstract：:Molecular-genetic properties of classical biotype Vibrio cholerae strains that caused the Asiatic cholera outbreak in 1942 in Russia have been investigated for the first time. Being characterized by high-level production of cholera toxin and toxin-coregulated adhesion pili both of which are the major virulence factors...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2003.10.004

    authors： Smirnova NI,Cheldyshova NB,Zadnova SP,Kutyrev VV

    更新日期：2004-03-01 00:00:00

  • The role of the temperature-regulated acyltransferase (PA3242) on growth, antibiotic resistance and virulence in Pseudomonas aeruginosa.

    abstract：:Pseudomonas aeruginosa (PAO1) is an important opportunistic pathogen that thrives in various environments. It is known that the structural variations of the lipopolysaccharide (LPS), including lipid A moiety play an important role in encountering environmental changes. Genes PA3242 and PA0011 have recently been report...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2016.09.019

    authors： Liang Y,Guo Z,Gao L,Guo Q,Wang L,Han Y,Duan K,Shen L

    更新日期：2016-12-01 00:00:00

  • Group B Streptococcus induces a caspase-dependent apoptosis in fetal rat lung interstitium.

    abstract：:Group B Streptococcus (GBS) is an important pathogen and is associated with sepsis and meningitis in neonates and infants. An ex vivo model that facilitates observations of GBS interactions with multiple host cell types over time was used to study its pathogenicity. GBS infections were associated with profound reducti...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2013.04.008

    authors： Kling DE,Tsvang I,Murphy MP,Newburg DS

    更新日期：2013-08-01 00:00:00

  • Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.

    abstract：:Orientia tsutsugamushi, an obligate intracellular bacterium, is the causative agent of scrub typhus which is histopathologically characterized by inflammatory manifestations, indicating that rickettsiae induce mechanisms that amplify the inflammatory response. To understand the pathogenesis of scrub typhus, we examine...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2003.08.006

    authors： Koh YS,Yun JH,Seong SY,Choi MS,Kim IS

    更新日期：2004-01-01 00:00:00

  • New Phage cocktail against infantile Sepsis bacteria.

    abstract：:A total of 54 positive blood aerobic cultures of suspected blood sepsis in neonates were purified, diagnosed and tested for antibiotic susceptibility. Six bacterial pathogens of Escherichia coli (10 isolates), Klebsiella pneumoniae (10 isolates), Haemophilus influenzae (4 isolates), Pseudomonas aeruginosa (3 isolates)...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2020.104447

    authors： Gatea Kaabi SA,Musafer HK

    更新日期：2020-11-01 00:00:00

  • Anticoccidial activity of Artemisia vestita (Anthemideae, Asteraceae) - a traditional herb growing in the Western Himalayas, Kashmir, India.

    abstract：:Coccidiosis, caused by various species of genus Eimeria, is a major parasitic disease in chicken. The increasing resistance of these parasites to currently used anticoccidial drugs has stimulated the search for new methods of control. As part of this effort, a study was designed to see the anticoccidial effect of diff...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2017.01.053

    authors： Ahad S,Tanveer S,Nawchoo IA,Malik TA

    更新日期：2017-03-01 00:00:00

  • The response regulator ArcA enhances biofilm formation in the vpsT manner under the anaerobic condition in Vibrio cholerae.

    abstract：:Vibrio cholerae, the agent of severe diarrheal disease cholera, is known to form biofilm to persist in the environmental and the host,s intestines. The bacteria execute a complex regulatory pathway producing virulence factors that allow colonization and cause disease in response to environmental signals in the intesti...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2020.104197

    authors： Xi D,Yang S,Liu Q,Li Y,Li Y,Yan J,Wang X,Ning K,Cao B

    更新日期：2020-07-01 00:00:00

  • Preparation of porcine enterotoxigenic Escherichia coli (ETEC) ghosts and immunogenic analysis in a mouse model.

    abstract：:Enterotoxignenic Escherichia coli (ETEC)-associated colibacillosis causes high levels of morbidity and mortality in neonatal piglets. Vaccination is among effective strategy to fight against ETEC-related diseases. Bacterial ghosts (BGs) are empty bacterial envelopes, which substain subtle antigenic comformation in bac...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2018.11.015

    authors： Ran X,Chen X,Wang S,Chang C,Wen X,Zhai J,Ni H

    更新日期：2019-01-01 00:00:00

  • The non-coding RNA rprA can increase the resistance to ampicillin in Escherichia coli.

    abstract：OBJECTIVES:The non-coding RNA rprA can increase the resistance to ampicillin in Escherichia coli. METHODS:Bacterial DNA was extracted by boiling method and then amplified using polymerase chain reaction (PCR) with two different primer sets. Recombinant pET28a/rprA-sense and -antisense plasmids were separately transfer...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2019.02.021

    authors： Sahni A,Hajjari M,Raheb J,Foroughmand AM,Asgari M

    更新日期：2019-04-01 00:00:00

  • Venom-derived peptide Mastoparan-1 eradicates planktonic and biofilm-embedded methicillin-resistant Staphylococcus aureus isolates.

    abstract：:During the past decade, cationic antimicrobial peptides (CAPs) have gained particular interest among researchers, since they often display broad-spectrum antimicrobial activity and low possibility of resistance emergence. This study aimed to investigate in vitro effectiveness of Mastoparan-1 (MP-1), a tetradecapeptide...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2018.04.008

    authors： Memariani H,Memariani M,Pourmand MR

    更新日期：2018-06-01 00:00:00

  • Immunogenic reactivity of recombinant PKF and AbOmpA proteins as serum resistance factors against sepsis of Acinetobacter baumannii.

    abstract：:Acinetobacter baumannii is considered as a major cause of nosocomial infection worldwide. Various vaccine formulations have been mostly studied based on secreted or surface-exposed proteins of A. baumannii in murine models. Serum resistance proteins are critical virulence factors in bloodstream infections. AbOmpA and ...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2019.03.031

    authors： Bolourchi N,Shahcheraghi F,Shirazi AS,Janani A,Bahrami F,Badmasti F

    更新日期：2019-06-01 00:00:00

  • Gene expression signatures characterizing the development of lymphocyte response during experimental Chlamydia pneumoniae infection.

    abstract：:In this study experimental mouse model for Chlamydia pneumoniae infection was used to elucidate the nature of immune response developing during primary and secondary infection. First we examined the mononuclear cells from different lymphoid organs in BALB/c mice during C. pneumoniae infection and detected a strong lym...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2009.01.006

    authors： Kyläniemi MK,Haveri A,Vuola JM,Puolakkainen M,Lahesmaa R

    更新日期：2009-05-01 00:00:00

  • Listeriolysin S may inhibit the anti-listerial properties of Lactobacillus plantarum.

    abstract：:Listeriosis is a serious infection linked to the consumption of food contaminated with Listeria monocytogenes. Outbreaks and mortality rates associated with this infection make it a significant public health concern. As biocontrol agents, probiotics such as Lactobacillus plantarum had been of interest for the promotio...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2019.103744

    authors： Mohammadzadeh R,Azadegan A,Kalani BS

    更新日期：2019-12-01 00:00:00

  • H9N2 swine influenza virus infection-induced damage is mediated by TRPM2 channels in mouse pulmonary microvascular endothelial cells.

    abstract：:Oxidative stress is implicated in the pathogenesis of influenza virus infection. Increasing evidences show that transient receptor potential melastatin 2 (TRPM2), a Ca2+-permeable non-selective cation channel, plays an important role in the pathomechanism of reactive oxygen species (ROS)-coupled diseases. The present ...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2020.104408

    authors： Wang S,Liang T,Luo Q,Li P,Zhang R,Xu M,Su J,Xu T,Wu Q

    更新日期：2020-11-01 00:00:00

  • Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant.

    abstract：:Little is known about the virulence factors of Burkholderia mallei, the etiologic agent of glanders. We employed subtractive hybridization to identify genetic determinants present in B. mallei but not in Burkholderia thailandensis, a non-pathogenic soil microbe. Three subtractive hybridization products were mapped to ...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1006/mpat.2000.0430

    authors： DeShazer D,Waag DM,Fritz DL,Woods DE

    更新日期：2001-05-01 00:00:00

  • Occurrence of Mycoplasma genitalium in the peritoneal fluid of fertile and infertile women with detailed analysis among infertile women.

    abstract：OBJECTIVE:To determine the frequency of occurrence of Mycoplasma genitalium infection in the peritoneal fluid of infertile women as compared to fertile women. MATERIALS AND METHODS:We have selected 162 infertile women aged 22-40 years as study subject and 162 women posted for elective caesarean section, were taken as ...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2019.02.006

    authors： Rekha S,Nooren M,Kalyan S,Mohan M,Bharti M,Monika R,Anita S,Kiran M,Vandana N

    更新日期：2019-04-01 00:00:00

  • Expression of mycobacterial antigens on murine dissociated Schwann cells infected with Mycobacterium leprae.

    abstract：:Mycobacterial antigens were detected in a cell surface ELISA on murine dissociated Schwann cells infected with Mycobacterium leprae. The time kinetics of expression and its refractoriness to modulation with monensin suggests that the antigens are likely to be integrated into the membrane during bacterial entry. This m...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1006/mpat.1996.0101

    authors： Birdi TJ,D'Souza S,Antia NH

    更新日期：1997-03-01 00:00:00

  • Virtual screening of plant compounds and nonsteroidal anti-inflammatory drugs for inhibition of quorum sensing and biofilm formation in Salmonella.

    abstract：:Salmonella belongs to the Enterobacteriaceae family which is widely distributed in the environment due to its adaptive capacity to stress conditions. In addition, Salmonella is able to perform a type of cell-to-cell communication called quorum sensing, which leads to differential gene expression. The quorum sensing sy...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2018.05.014

    authors： Almeida FA,Vargas ELG,Carneiro DG,Pinto UM,Vanetti MCD

    更新日期：2018-08-01 00:00:00

  • Interplay between MgtC and PagC in Salmonella enterica serovar Typhimurium.

    abstract：:In Salmonella enterica serovar Typhimurium, MgtC and PagC are positively regulated by the PhoP-PhoQ two-component system, which is activated under magnesium deprivation. Both MgtC and PagC are of unknown function but have been involved in intramacrophage survival. We have found that the amount of PagC is lowered in a ...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2008.06.001

    authors： Alix E,Miki T,Felix C,Rang C,Figueroa-Bossi N,Demettre E,Blanc-Potard AB

    更新日期：2008-09-01 00:00:00

  • The major circulating immunosuppressive activity in American visceral leishmaniasis patients is associated with a high-molecular weight fraction and is not mediated by IgG, IgG immune complexes or lipoproteins.

    abstract：:Opportunistic infections, due to disease-related immunosuppression, constitute the major cause of death in American visceral leishmaniasis (AVL). Sera from these patients (AVL sera) non-specifically inhibit the in vitro proliferative response of normal human lymphocytes to lectins or antigens. In the present work, the...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2006.02.005

    authors： Soares NM,Ferraz TP,Nascimento EG,Carvalho EM,Pontes-de-Carvalho L

    更新日期：2006-06-01 00:00:00

  • PECAM-1 is involved in neutrophil transmigration across Histophilus somni treated bovine brain endothelial cells.

    abstract：:Histophilus somni (H. somni) is a gram-negative bacterial pathogen that causes respiratory, reproductive, and central nervous system disease in cattle. The hallmark of systemic H. somni infection is diffused vasculitis that can lead to an acute central nervous system disease known as thrombotic meningoencephalitis (TM...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2009.06.001

    authors： Tiwari R,Sullivan J,Czuprynski CJ

    更新日期：2009-09-01 00:00:00