Comparison of virulence of Mycobacterium avium complex (MAC) strains isolated from AIDS and non-AIDS patients.

Abstract:

:Mycobacterium avium complex (MAC) strains from AIDS and non-AIDS patients and from the environment were studied for their colony morphology and virulence in beige mice. The majority of the MAC isolates from AIDS patients, in contrast to those from non-AIDS patients and the environment, showed increased virulence. Similarly, the majority of the MAC isolates from AIDS patients formed smooth transparent (ST) colonies, whereas most of the non-AIDS isolates formed smooth opaque (SO) or intermediate (IM) type of colonies. MAC isolates from the same AIDS patient obtained at different times were found to be heterogenic with respect to serotype, RFLP and glycolipid patterns, suggesting that these patients might be infected with more than one strain of MAC.

journal_name

Microb Pathog

journal_title

Microbial pathogenesis

authors

Reddy VM,Parikh K,Luna-Herrera J,Falkinham JO 3rd,Brown S,Gangadharam PR

doi

10.1006/mpat.1994.1013

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

121-30

issue

2

eissn

0882-4010

issn

1096-1208

pii

S0882401084710138

journal_volume

16

pub_type

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