当前位置： SCI文献检索 > MICROBIAL PATHOGENESIS期刊下所有文献 > Acute and late disease induced by murine coronavirus, strain JHM, in a series of recombinant inbred strains between BALB/cHeA and STS/A mice.

Acute and late disease induced by murine coronavirus, strain JHM, in a series of recombinant inbred strains between BALB/cHeA and STS/A mice.

Abstract：

:To examine the genetic control of acute and late disease induced by a murine coronavirus, strain JHM (JHMV), BALB/cHeA, STS/A, F1 hybrids and 13 recombinant inbred (RI) strains between BALB/cHeA and STS/A mouse strains were inoculated intracerebrally with 100 pfu of JHMV. All the BALB/cHeA mice died within 2 weeks from acute encephalitis. In contrast, STS/A mice were shown to be partially resistant, with a mortality rate of 30%, longer survival times and lower rates of viral production. The mortality rates, survival times and viral titers of F1 hybrids and the RI strains varied, suggesting involvement of multiple genes. STS/A, F1 hybrid and RI mice surviving the acute infection occasionally developed severe paraparesis about 1 month post-infection. In these mice, vacuolar degeneration, astrocytosis, the absence of perivascular cuffing and minimal demyelination were found in the central nervous system. No infectious virus could be recovered from these mice. Although the paralysis of delayed onset was limited to STS/A, F1 hybrid and eight of the 13 RI strains, the incidence varied significantly among the RI strains. These results may suggest that JHMV-induced late disease is also under multifactorial control. The pathogenesis of JHMV infection is discussed.

journal_name

Microb Pathog

journal_title

Microbial pathogenesis

authors

Kyuwa S,Yamaguchi K,Toyoda Y,Fujiwara K,Hilgers J

doi

10.1016/0882-4010(92)90112-2

subject

Has Abstract

pub_date

1992-02-01 00:00:00

pages

95-104

issue

2

eissn

0882-4010

issn

1096-1208

pii

0882-4010(92)90112-2

journal_volume

12

pub_type

杂志文章

相关文献

MICROBIAL PATHOGENESIS文献大全
  • Structural basis for isoniazid resistance in KatG double mutants of Mycobacterium tuberculosis.

    abstract：:The failure of drugs for effective treatment against infectious diseases can be attributed to resistant forms of causative agents. The evasive nature of Mycobacterium tuberculosis is partly associated to its physical features, such as having a thick cell wall and incorporation of beneficial mutations leading to drug r...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2019.02.003

    authors： Rabha A,Singh A,Grover S,Kumari A,Pandey B,Grover A

    更新日期：2019-04-01 00:00:00

  • Restriction fragment length polymorphism of PCR amplified papE gene products is correlated with complete serotype among uropathogenic Escherichia coli isolates.

    abstract：:Using whole bacteria, rather than extracted, purified DNA samples, we amplified the papE gene sequences from 63 Escherichia coli isolates belonging to O serogroups O1, O2 and O6. These isolates were from collections separated temporally as well as geographically: from four cities in the US and one in Sweden. PCR ampli...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1006/mpat.1996.0033

    authors： Jantausch BA,Hull SI

    更新日期：1996-06-01 00:00:00

  • The C-terminus of IpaC is required for effector activities related to Shigella invasion of host cells.

    abstract：:Invasion plasmid antigen C (IpaC) is secreted by the Shigella flexneri type III secretion system (TTSS) as an essential trigger of epithelial cell invasion. At the molecular level, IpaC possesses a distinct functional organization. The IpaC C-terminal region between amino acids 319 and 345 is predicted to form a coile...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2008.06.003

    authors： Terry CM,Picking WL,Birket SE,Flentie K,Hoffman BM,Barker JR,Picking WD

    更新日期：2008-10-01 00:00:00

  • Lack of association between hemolysin production and acute inflammation in human urinary tract infection.

    abstract：:Hemolysins are cytolytic proteins which have been extensively characterized at the molecular level, however, their in vivo functions remain unclear. This study analyzed the association of hemolysin production with the inflammatory response in patients with urinary tract infection (UTI). Infants and children with their...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1006/mpat.1993.1045

    authors： Connell H,de Man P,Jodal U,Lincoln K,Svanborg C

    更新日期：1993-06-01 00:00:00

  • Gene expression signatures characterizing the development of lymphocyte response during experimental Chlamydia pneumoniae infection.

    abstract：:In this study experimental mouse model for Chlamydia pneumoniae infection was used to elucidate the nature of immune response developing during primary and secondary infection. First we examined the mononuclear cells from different lymphoid organs in BALB/c mice during C. pneumoniae infection and detected a strong lym...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2009.01.006

    authors： Kyläniemi MK,Haveri A,Vuola JM,Puolakkainen M,Lahesmaa R

    更新日期：2009-05-01 00:00:00

  • AdeB efflux pump gene knockdown by mRNA mediated peptide nucleic acid in multidrug resistance Acinetobacter baumannii.

    abstract：:Multidrug-resistant Acinetobacter baumannii isolates cause critical problems in health-care environments. AdeABC is a resistance-nodulation-cell division (RND)-type multidrug efflux pump conferring resistance to clinically essential antibiotics in A. baumannii, such as ciprofloxacin. This study aimed to target adeB ge...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2019.103825

    authors： Abdi SN,Ghotaslou R,Asgharzadeh M,Mehramouz B,Hasani A,Baghi HB,Tanomand A,Narenji H,Yousefi B,Gholizadeh P,Yousefi M,Bastami M,Ganbarov K,Samadi Kafil H

    更新日期：2020-02-01 00:00:00

  • The role of the temperature-regulated acyltransferase (PA3242) on growth, antibiotic resistance and virulence in Pseudomonas aeruginosa.

    abstract：:Pseudomonas aeruginosa (PAO1) is an important opportunistic pathogen that thrives in various environments. It is known that the structural variations of the lipopolysaccharide (LPS), including lipid A moiety play an important role in encountering environmental changes. Genes PA3242 and PA0011 have recently been report...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2016.09.019

    authors： Liang Y,Guo Z,Gao L,Guo Q,Wang L,Han Y,Duan K,Shen L

    更新日期：2016-12-01 00:00:00

  • Biosynthesis of silver nanoparticles using a probiotic Bacillus licheniformis Dahb1 and their antibiofilm activity and toxicity effects in Ceriodaphnia cornuta.

    abstract：:In the present study, we synthesized and characterized a probiotic Bacillus licheniformis cell free extract (BLCFE) coated silver nanoparticles (BLCFE-AgNPs). These BLCFE-AgNPs were characterized by UV-visible spectrophotometer, XRD, EDX, FTIR, TEM and AFM. A strong surface plasmon resonance centered at 422 nm in UV-v...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2016.01.014

    authors： Shanthi S,Jayaseelan BD,Velusamy P,Vijayakumar S,Chih CT,Vaseeharan B

    更新日期：2016-04-01 00:00:00

  • Susceptibility of mouse mammary glands to murine gammaherpesvirus 72 (MHV-72) infection: evidence of MHV-72 transmission via breast milk.

    abstract：:Murine gammaherpesvirus 72 (MHV-72) is a virus of wild rodents and serves as a convenient small animal model to understand the pathogenesis of Epstein-Barr virus (EBV) and human herpesvirus 8 (HHV8) infection. In laboratory mice MHV-72 causes an acute infection of lung epithelial cells and establishes the latency in B...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1006/mpat.2001.0441

    authors： Raslova H,Berebbi M,Rajcani J,Sarasin A,Matis J,Kudelova M

    更新日期：2001-08-01 00:00:00

  • Occurrence of virulence factors in Cronobacter sakazakii and Cronobacter malonaticus originated from clinical samples.

    abstract：BACKGROUND:Cronobacter spp. are Gram-negative, facultative-anaerobic, non-spore forming, enteric coliform bacteria, which belongs to the Enterobacteriaceae family. Cronobacter spp. are opportunistic pathogens that have brought rare but life-threatening infections such as meningitis, necrotizing enterocolitis and bloods...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2018.12.011

    authors： Holý O,Cruz-Córdova A,Xicohtencatl-Cortes J,Hochel I,Parra-Flores J,Petrželová J,Fačevicová K,Forsythe S,Alsonosi A

    更新日期：2019-02-01 00:00:00

  • Pros and cons of direct genotyping on tuberculosis clinical samples.

    abstract：OBJECTIVE:Prompt genotyping of Mycobacterium tuberculosis (M. tuberculosis) is crucial for improving molecular epidemiological investigation of tuberculosis (TB). METHODS:We performed a retrospective study to evaluate the use of 24 loci MIRU-VNTR (mycobacterial interspersed repetitive unit-variable number of tandem-re...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2016.12.025

    authors： Sadegh H,Kargarpour Kamakoli M,Farmanfarmaei G,Masoumi M,Abdolrahimi F,Fateh A,Ebrahimzadeh N,Rahimi Jamnani F,Vaziri F,Siadat SD

    更新日期：2017-02-01 00:00:00

  • A 26 kDa protein of helicobacter pylori shows alkyl hydroperoxide reductase (AhpC) activity and the mono-cistronic transcription of the gene is affected by pH.

    abstract：:The 26 kDa protein of Helicobacter pylori, with 67% amino acid identity to alkyl hydroperoxide reductase (AhpC) of Campylobacter jejuni, was studied. We wanted to evaluate it the protein has AhpC activity. Therefore, an Escherichia coli mutant defective for alkyl hydroperoxide reductase and a plasmid expressing the 26...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1006/mpat.2000.0388

    authors： Lundström AM,Bölin I

    更新日期：2000-11-01 00:00:00

  • Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.

    abstract：:Orientia tsutsugamushi, an obligate intracellular bacterium, is the causative agent of scrub typhus which is histopathologically characterized by inflammatory manifestations, indicating that rickettsiae induce mechanisms that amplify the inflammatory response. To understand the pathogenesis of scrub typhus, we examine...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2003.08.006

    authors： Koh YS,Yun JH,Seong SY,Choi MS,Kim IS

    更新日期：2004-01-01 00:00:00

  • Evaluation of antibacterial and modifying action of catechin antibiotics in resistant strains.

    abstract：:Diseases caused by bacteria are today one of the great problems of present time. Access to over-the-counter medication, the indiscriminate use of antibacterials and high rates of hospitalization have contributed to the increase in cases. This picture has led to the search for new alternative drugs. Thus, secondary met...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2017.12.058

    authors： Gomes FMS,da Cunha Xavier J,Dos Santos JFS,de Matos YMLS,Tintino SR,de Freitas TS,Coutinho HDM

    更新日期：2018-02-01 00:00:00

  • Staphylococcal cassette chromosome mec (SCCmec) and characterization of the attachment site (attB) of methicillin resistant Staphylococcus aureus (MRSA) and methicillin susceptible Staphylococcus aureus (MSSA) isolates.

    abstract：:This study was designed to screen for SCCmec types and to characterize the attachment site (attB) and universal insertion site (orfX) of SCCmec in a collection of 27 isolates (n = 11) methicillin resistant S. aureus and (n = 16) methicillin susceptible S. aureus isolates in Malaysia. Screening of SCCmec types and char...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2018.07.033

    authors： Bitrus AA,Zunita Z,Khairani-Bejo S,Othman S,Ahmad Nadzir NA

    更新日期：2018-10-01 00:00:00

  • Group B Streptococcus induces a caspase-dependent apoptosis in fetal rat lung interstitium.

    abstract：:Group B Streptococcus (GBS) is an important pathogen and is associated with sepsis and meningitis in neonates and infants. An ex vivo model that facilitates observations of GBS interactions with multiple host cell types over time was used to study its pathogenicity. GBS infections were associated with profound reducti...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2013.04.008

    authors： Kling DE,Tsvang I,Murphy MP,Newburg DS

    更新日期：2013-08-01 00:00:00

  • Polymorphisms in the Pseudomonas aeruginosa type III secretion protein, PcrV - implications for anti-PcrV immunotherapy.

    abstract：:The type III secretion system of Pseudomonas aeruginosa, responsible for acute infection, is composed of over twenty proteins that facilitate cytotoxin injection directly into host cells. Integral to this process is production and secretion of PcrV. Administration of a recently developed, anti-PcrV immunoglobulin, eit...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2010.02.008

    authors： Lynch SV,Flanagan JL,Sawa T,Fang A,Baek MS,Rubio-Mills A,Ajayi T,Yanagihara K,Hirakata Y,Kohno S,Misset B,Nguyen JC,Wiener-Kronish JP

    更新日期：2010-06-01 00:00:00

  • Correlation between ability of biofilm formation with their responsible genes and MDR patterns in clinical and environmental Acinetobacter baumannii isolates.

    abstract：:Acinetobacter baumannii potential to form biofilm and exhibit multiple antibiotic resistances may be responsible in its survival in hospital environment. Accordingly, our study was aimed to determine the correlation between ability of biofilm formation and the frequency of biofilm related genes with antibiotic resista...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2017.04.039

    authors： Bardbari AM,Arabestani MR,Karami M,Keramat F,Alikhani MY,Bagheri KP

    更新日期：2017-07-01 00:00:00

  • The multi-faceted potential of plant-derived metabolites as antimicrobial agents against multidrug-resistant pathogens.

    abstract：:Multidrug-resistant (MDR) pathogens are currently causing serious problems globally in the medical setting. Improper and extensive usage of antibiotics results in a selective pressure supporting the rise of antibiotic-resistant microbes. Many key cellular bacterial components, including enzymes and small noncoding RNA...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章,评审

    doi：10.1016/j.micpath.2018.01.043

    authors： Shin J,Prabhakaran VS,Kim KS

    更新日期：2018-03-01 00:00:00

  • Interest of bacterial pangenome analyses in clinical microbiology.

    abstract：:Thanks to the progress and decreasing costs in genome sequencing technologies, more than 250,000 bacterial genomes are currently available in public databases, covering most, if not all, of the major human-associated phylogenetic groups of these microorganisms, pathogenic or not. In addition, for many of them, sequenc...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2020.104275

    authors： Anani H,Zgheib R,Hasni I,Raoult D,Fournier PE

    更新日期：2020-12-01 00:00:00

  • Association between HLA-Ⅱgene polymorphism and Helicobacter pylori infection in Asian and European population: A meta-analysis.

    abstract：BACKGROUND:It is generally considered that HLA-Ⅱ genes contribute to the Helicobacter pylori (Hp) infection and disease development process. AIMS:To perform a meta-analysis to explore the relationship between HLA-Ⅱgene polymorphism and host susceptibility to Hp infection. METHODS:Relevant cohort studies, case-control...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.micpath.2015.03.011

    authors： Wang J,Zhang Q,Liu Y,Han J,Ma X,Luo Y,Liang Y,Zhang L,Hu Y

    更新日期：2015-05-01 00:00:00

  • Geniposide reduces Staphylococcus aureus internalization into bovine mammary epithelial cells by inhibiting NF-κB activation.

    abstract：:Staphylococcus aureus (S.aureus), a Gram-positive organism, is a frequent cause of subclinical mastitis. Geniposide, an iridoid glucoside isolated from the fruits of Gardenia jasminoides, has been reported to exhibit antibacterial and anti-inflammatory properties. The ability of S. aureus internalizing into bovine mam...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2018.10.002

    authors： Wei Z,Su K,Jiang P,Shi M,Wang J,Xie G

    更新日期：2018-12-01 00:00:00

  • Quantification of Staphylococcus aureus cell surface adhesins using flow cytometry.

    abstract：:The initiation of many infectious diseases involves specific adhesion of bacteria to host tissue proteins and carbohydrates. Staphylococcus aureus is known to bind specifically to several proteins in the extracellular matrix (ECM). We report the quantification of the collagen and fibronectin adhesin densities on the s...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1006/mpat.2000.0399

    authors： Mohamed N,Visai L,Speziale P,Ross JM

    更新日期：2000-12-01 00:00:00

  • Purified Pasteurella haemolytica leukotoxin induces expression of inflammatory cytokines from bovine alveolar macrophages.

    abstract：:We obtained biologically active purified leukotoxin (Lkt) from Pasteurella haemolytica serotypel, strain 12296 using preparative sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Three species of Lkt of molecular masses 95, 100, and 104 kDa were obtained. Purity of all three species of Lkt was conf...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/s0882-4010(05)80001-4

    authors： Yoo HS,Rajagopal BS,Maheswaran SK,Ames TR

    更新日期：1995-04-01 00:00:00

  • Identification of 60 secreted proteins for Mycoplasma bovis with secretome assay.

    abstract：:Mycoplasma bovis is a risky pathogen mainly responsible for pneumonia and mastitis in cattle. Up to date, its pathogenesis is not clear. Since secreted proteins have a tricky role in M. bovis pathogenesis, this study was designed to systematically reveal M. bovis secretome and potential role in virulence of the pathog...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2020.104135

    authors： Zubair M,Muhamed SA,Khan FA,Zhao G,Menghwar H,Faisal M,Zhang H,Zhu X,Rasheed MA,Chen Y,Marawan MA,Chen H,Guo A

    更新日期：2020-06-01 00:00:00

  • Molecular surveillance of candidemia due to Candida albicans among cancer patients during 2009 to 2013 by microsatellite typing.

    abstract：BACKGROUND:Since the high morbidity and mortality of candidemia among cancer patients, the epidemiology has been underlined. In recent years, Candida species genotyping has been established, which could provide detail characteristics of epidemiology and has been underscored for candidemia preventing strategies. METHOD...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2015.03.005

    authors： Li D,Li X,Xia R,Zhang W,Zheng S,Zhang Q,Bai C,Zhang P

    更新日期：2015-04-01 00:00:00

  • Comparative genomic analyses of two novel qnrVC6 carrying multidrug-resistant Pseudomonas. spp strains.

    abstract：OBJECTIVES:This study focused on the comparative genomic analyses of two qnrVC6 carrying Pseudomonas spp. strains which might give us insights on the similarity and difference in the genomic contexts of qnrVC6 gene. METHODS:Comparative genomic analyses of the novel qnrVC6 carrying Pseudomonas spp. genomes with emphasi...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2018.07.026

    authors： Liu J,Yang L,Li L,Li B,Chen D,Xu Z

    更新日期：2018-10-01 00:00:00

  • In vitro evidence of two-component system phosphorylation between the Mycobacterium tuberculosis TrcR/TrcS proteins.

    abstract：:Two-component regulatory proteins, histidine kinases and response regulators, function in bacteria as sensing and adaptive factors in response to a wide range of environmental stimuli. Conserved histidine and glycine regions of histidine kinase sensor proteins were used to design degenerate oligonucleotide primers for...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1006/mpat.1998.0265

    authors： Haydel SE,Dunlap NE,Benjamin WH Jr

    更新日期：1999-04-01 00:00:00

  • Adherence capability and safety assessment of an indigenous probiotic strain Lactobacillus rhamnosus MTCC-5897.

    abstract：:With the growing interest in probiotic microorganisms based on their well established immense health benefits, the present investigation was aimed to assess the adhesion potential and safety of probiotic Lactobacillus rhamnosus MTCC- 5897 (LR) before it can be put into a probiotic formulations. L. rhamnosus showed an ...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2019.03.009

    authors： Bhat MI,Singh VK,Sharma D,Kapila S,Kapila R

    更新日期：2019-05-01 00:00:00

  • Langerhans cells (CD1a and CD207), dermal dendrocytes (FXIIIa) and plasmacytoid dendritic cells (CD123) in skin lesions of leprosy patients.

    abstract：:The clinical course of infection with Mycobacterium leprae varies widely and depends on the pattern of the host immune response. Dendritic cells play an important role in the activation of the innate and adaptive immune system and seem to be essential for the development of the disease. To analyze the presence of epid...

    journal_title：Microbial pathogenesis

    pub_type： 杂志文章

    doi：10.1016/j.micpath.2015.11.013

    authors： Hirai KE,Aarão TL,Silva LM,de Sousa JR,de Souza J,Dias LB Jr,Carneiro FR,Fuzii HT,Quaresma JA

    更新日期：2016-02-01 00:00:00