Molecular surveillance of candidemia due to Candida albicans among cancer patients during 2009 to 2013 by microsatellite typing.

Abstract:

BACKGROUND:Since the high morbidity and mortality of candidemia among cancer patients, the epidemiology has been underlined. In recent years, Candida species genotyping has been established, which could provide detail characteristics of epidemiology and has been underscored for candidemia preventing strategies. METHODS:Data of cancer patients with candidemia and hospitalized in Tianjin Medical University Cancer Institute and Hospital (TMUCIH) during 2009-2013 were reviewed. Species identification was carried out by using VITEK-2 Compact. Microsatellite typing was performed for molecular analysis. SPSS 20.0 and MVSP 3.22 software were used for statistical and clustering analysis, respectively. RESULTS:Total of 36 isolates of Candida albicans were recovered from 36 cancer patients with nosocomial candidemia in TMUCIH during the period of 2009-2013 included in the study. Total of 17 genotypes were identified and 2 of them were endemic genotypes, which caused 21 (58.3%) of 36 episodes of candidemia. Hepatobiliary oncology, ICU and gastrointestinal oncology were the main wards of infections due to endemic strains. Gastrointestinal cancer and insertion of a nasogastric tube were the predictors of infections caused by endemic strains (p = 0.014 and p = 0.041, respectively). For the 36 cases, crude mortality was up to 30.6%, and there was no significant difference between infections due to endemic and non-endemic strains (p = 0.077). CONCLUSIONS:This study proved that endemic stains of C. albicans could exist for a long period and mainly in a few wards. Patients with gastrointestinal cancer or nasogastric tube insertion were more sensitive to endemic C. albicans.

journal_name

Microb Pathog

journal_title

Microbial pathogenesis

authors

Li D,Li X,Xia R,Zhang W,Zheng S,Zhang Q,Bai C,Zhang P

doi

10.1016/j.micpath.2015.03.005

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

28-32

eissn

0882-4010

issn

1096-1208

pii

S0882-4010(15)00032-7

journal_volume

81

pub_type

杂志文章
  • GroEL PCR- RFLP - An efficient tool to discriminate closely related pathogenic Vibrio species.

    abstract::Vibrio sp. are autochthonous to marine and estuarine waters. Several species of Vibrio are pathogens. It is of utmost importance to detect and discriminate the Vibrio sp. that are often involved in food and water borne infections. Since 16S rRNA based identification has limited utility in differentiating the closely r...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2017.02.029

    authors: Silvester R,Alexander D,Antony AC,Hatha M

    更新日期:2017-04-01 00:00:00

  • The role of Listeria monocytogenes cell wall surface anchor protein LapB in virulence, adherence, and intracellular replication.

    abstract::Lmof2365_2117 is a Listeria monocytogenes putative cell wall surface anchor protein with a conserved domain found in collagen binding proteins. We constructed a deletion mutation in lmof2365_2117 in serotype 4b strain F2365, evaluated its virulence, and determined its ability to adhere and invade colonic epithelial ce...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2015.12.012

    authors: Reddy S,Akgul A,Karsi A,Abdelhamed H,Wills RW,Lawrence ML

    更新日期:2016-03-01 00:00:00

  • Evaluation of a Yersinia pestis mutant impaired in a thermoregulated type VI-like secretion system in flea, macrophage and murine models.

    abstract::Type VI secretion systems (T6SSs) have been identified recently in several Gram-negative organisms and have been shown to be associated with virulence in some bacterial pathogens. A T6SS of Yersinia pestis CO92 (locus YPO0499-YPO0516) was deleted followed by investigation of the phenotype of this mutation. We observed...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2009.08.005

    authors: Robinson JB,Telepnev MV,Zudina IV,Bouyer D,Montenieri JA,Bearden SW,Gage KL,Agar SL,Foltz SM,Chauhan S,Chopra AK,Motin VL

    更新日期:2009-11-01 00:00:00

  • Expression of Vibrio cholerae zonula occludens toxin and analysis of its subcellular localization.

    abstract::Vibrio cholerae elaborates zonula occludens toxin (Zot), a protein that increases the permeability of small intestinal mucosa by opening intercellular tight junctions. The zot gene is located, together with the genes encoding CT and Ace enterotoxins, within the genome of V. cholerae filamentous phage CTXsmall ef, Cyri...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1006/mpat.1999.0312

    authors: Uzzau S,Cappuccinelli P,Fasano A

    更新日期:1999-12-01 00:00:00

  • A new subtype of a natural viral inhibitor (CVI) that is stable in the gastrointestinal tract.

    abstract::A virus inhibitor found in gastric secretions and in extracts from gastrointestinal tissues is described. The inhibitor shares a number of characteristics with the recently described contact-blocking virus inhibitor (CVI), which is produced by unstimulated cells in culture, and occurs naturally in some body fluids. Th...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/0882-4010(86)90048-3

    authors: Baron JL,Li JL,McKerlie ML,Shabot JM,Coppenhaver DH

    更新日期:1986-06-01 00:00:00

  • Bioavailability-enhanced Resveramax™ modulates quorum sensing and inhibits biofilm formation in Pseudomonas aeruginosa PAO1.

    abstract::Quorum sensing (QS), a cell-to-cell communication mechanism present in many bacterial species plays a key role in regulating the virulence factor and biofilm formation in many pathogens, which causes severe public health risk. Therefore, interfering with QS mechanism offers an attractive strategy to combat bacterial i...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2017.01.015

    authors: Vasavi HS,Sudeep HV,Lingaraju HB,Shyam Prasad K

    更新日期:2017-03-01 00:00:00

  • Purification and some properties of Shiga-like toxin from Escherichia coli O157:H7 that is immunologically identical to Shiga toxin.

    abstract::A cytotoxin to Vero cells (Shiga-like toxin), which was neutralized by antibody against purified Shiga toxin produced by Shigella dysenteriae 1, was purified from Escherichia coli O157:H7, isolated from a patient with hemorrhagic colitis. The purification procedure consisted of ammonium sulfate fractionation, DEAE-cel...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/0882-4010(87)90076-3

    authors: Noda M,Yutsudo T,Nakabayashi N,Hirayama T,Takeda Y

    更新日期:1987-05-01 00:00:00

  • Antibacterial mechanisms of cinnamon and its constituents: A review.

    abstract:BACKGROUND:In the current healthcare environment, an alarming rise in multi-drug resistant bacterial infections has led to a global health threat. The lack of new antibiotics has created a need for developing alternative strategies. OBJECTIVE:Understanding the antibacterial mechanisms of cinnamon and its constituents ...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章,评审

    doi:10.1016/j.micpath.2018.04.036

    authors: Vasconcelos NG,Croda J,Simionatto S

    更新日期:2018-07-01 00:00:00

  • Amphotericin B-conjugated biogenic silver nanoparticles as an innovative strategy for fungal infections.

    abstract::New strategies are required to improve the efficacy of drugs and to treat the emerging microbial resistance. An effective strategy is to combine drugs with metal nanoparticles for the control of microbial infections and resistance. Keeping in view this fact, we developed a facile and eco-friendly protocol for the synt...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2016.08.031

    authors: Ahmad A,Wei Y,Syed F,Tahir K,Taj R,Khan AU,Hameed MU,Yuan Q

    更新日期:2016-10-01 00:00:00

  • Mutation of purD and purF genes further attenuates Brucella abortus strain RB51.

    abstract::In the present study, transposon mutagenesis was used to further attenuate Brucella abortus RB51 vaccine strain. Two purD and purF mutants were constructed, characterized and evaluated for attenuation via intracellular survival in murine macrophage-like RAW264.7 and HeLa cells, and by clearance in BALB/c mice. The pur...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2014.12.003

    authors: Truong QL,Cho Y,Barate AK,Kim S,Watarai M,Hahn TW

    更新日期:2015-02-01 00:00:00

  • Interaction of heat-stable enterotoxins with human colonic (T84) cells: modulation of the activation of guanylyl cyclase.

    abstract::Heat-stable enterotoxins (ST) activate guanylyl cyclase in T84 cells, rapidly and specifically. Activation is monitored by cGMP production and occurs at lower concentrations of ST than required for eliciting fluid accumulation in suckling mice. Atrial natriuretic factor (ANF) neither activates guanylyl cyclase nor mod...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/0882-4010(92)90055-s

    authors: Visweswariah SS,Shanthi G,Balganesh TS

    更新日期:1992-03-01 00:00:00

  • Role of H-2 and non-H-2-related genes in mouse susceptibility to Chlamydia psittaci.

    abstract::The genetic control of mouse susceptibility to Chlamydia psittaci was investigated after intravenous inoculation of 2 x 10(5) plaque-forming units (pfu). Splenic counts 6 days after inoculation gave the level of susceptibility. Results from inoculation of mice from H-2 congenic strains with three different genetic bac...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1006/mpat.1994.1023

    authors: Buzoni-Gatel D,Bernard F,Pla M,Rodolakis A,Lantier F

    更新日期:1994-03-01 00:00:00

  • Cervicovaginal microbiota dysbiosis correlates with HPV persistent infection.

    abstract::HPV persistent infection is a main event leading to the development of cervical intraepithelial neoplasia and cervical cancer. Earlier to distinguish HPV persistent and transient infection is meaningful but the methods are limited. This study used 16S rDNA sequencing to determine the cervicovaginal microbiota of HPV p...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2020.104617

    authors: Qingqing B,Jie Z,Songben Q,Juan C,Lei Z,Mu X

    更新日期:2020-11-15 00:00:00

  • Expression of mycobacterial antigens on murine dissociated Schwann cells infected with Mycobacterium leprae.

    abstract::Mycobacterial antigens were detected in a cell surface ELISA on murine dissociated Schwann cells infected with Mycobacterium leprae. The time kinetics of expression and its refractoriness to modulation with monensin suggests that the antigens are likely to be integrated into the membrane during bacterial entry. This m...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1006/mpat.1996.0101

    authors: Birdi TJ,D'Souza S,Antia NH

    更新日期:1997-03-01 00:00:00

  • Comparison of adhesin genes expression among Klebsiella oxytoca ESBL-non-producers in planktonic and biofilm mode of growth, and imipenem sublethal exposure.

    abstract:BACKGROUND:Bacterial adhesins play an important role in the bacterial attachment and colonization. The aim of this study was comparison of adhesin genes expression in the planktonic and biofilm mode of growth among ESBL-non-producers isolates of K. oxytoca and effect of imipenem. MATERIALS AND METHODS:A total of eight...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2019.103558

    authors: Alkhudhairy MK,Alshadeedi SMJ,Mahmood SS,Al-Bustan SA,Ghasemian A

    更新日期:2019-09-01 00:00:00

  • The global prevalence and risk factors of Toxoplasma gondii among foxes: A systematic review and meta-analysis.

    abstract::Toxoplasma gondii is one of the most successful intracellular protozoan parasites in the world, which can infect most warm-blooded animals including foxes in the world and cause toxoplasmosis. This is the first meta-analysis to assess the overall prevalence and potential risk factors of T. gondii among foxes in the wo...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2020.104699

    authors: Wei XY,Gao Y,Lv C,Wang W,Chen Y,Zhao Q,Gong QL,Zhang XX

    更新日期:2020-12-28 00:00:00

  • High-resolution melting-curve (HRM) analysis for C. meleagridis identification in stool samples.

    abstract:BACKGROUND:Cryptosporidiosis represents a major public health problem. This infection, caused by a protozoan parasite of the genus Cryptosporidium, has been reported worldwide as a frequent cause of diarrhoea. In the immunocompetent host, the typical watery diarrhea can be self-limiting. However, it is severe and chron...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2017.12.070

    authors: Chelbi H,Essid R,Jelassi R,Bouzekri N,Zidi I,Ben Salah H,Mrad I,Ben Sghaier I,Abdelmalek R,Aissa S,Bouratbine A,Aoun K

    更新日期:2018-02-01 00:00:00

  • Elevated production of IL-36α in chronic hepatitis B virus-infected patients correlates with viral load.

    abstract::Chronic hepatitis B (CHB) infection is a typical inflammatory disease characterized by a dysregulated expression of cytokines, which contributes to the pathogenesis of chronic Hepatitis B virus (HBV) infection. IL-36 cytokines (IL-36α, IL-36β, IL-36γ and IL-36Ra) are important players in infection and immunity. Howeve...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2017.11.023

    authors: Gong Y,Tingxi Z,Qing L,Guozhen Z,Bing T,Xiaoliang Y,Yan W,Wenjuan J,Yan X,Hui L,Xue H,Zebo Y

    更新日期:2017-12-01 00:00:00

  • Induction of monocyte chemoattractant protein-1 (MCP-1) production by Pseudomonas nitrite reductase in human pulmonary type II epithelial-like cells.

    abstract::Monocyte chemoattractant protein-1 (MCP-1), a chemoattractant for monocytes, is presumed to play a pivotal role in the recruitment and accumulation of monocytes in various diseases including pulmonary infections. We examined here whether or not Pseudomonas nitrite reductase (PNR), a recently identified IL-8 inducer in...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1006/mpat.1999.0320

    authors: Sar B,Oishi K,Wada A,Hirayama T,Matsushima K,Nagatake T

    更新日期:2000-01-01 00:00:00

  • Polymorphisms in the Pseudomonas aeruginosa type III secretion protein, PcrV - implications for anti-PcrV immunotherapy.

    abstract::The type III secretion system of Pseudomonas aeruginosa, responsible for acute infection, is composed of over twenty proteins that facilitate cytotoxin injection directly into host cells. Integral to this process is production and secretion of PcrV. Administration of a recently developed, anti-PcrV immunoglobulin, eit...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2010.02.008

    authors: Lynch SV,Flanagan JL,Sawa T,Fang A,Baek MS,Rubio-Mills A,Ajayi T,Yanagihara K,Hirakata Y,Kohno S,Misset B,Nguyen JC,Wiener-Kronish JP

    更新日期:2010-06-01 00:00:00

  • Expression of avian sarcoma virus genes in tumor cells derived from different periods of tumor growth.

    abstract::Avian sarcoma virus (ASV)-induced tumor cells that are derived from regressing neoplasms contain about 75% less pp60src kinase activity than do progressively-growing tumor cells. Paradoxically, the polyadenylated RNAs extracted from 'regressor' cells found in regressing neoplasms are much more productive than those fr...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/0882-4010(87)90102-1

    authors: Poulin L,Wainberg MA

    更新日期:1987-02-01 00:00:00

  • Mycoplasma pneumoniae-related hepatitis in children.

    abstract::Mycoplasma pneumoniae (M. pneumoniae) is a small bacterium characterized by the absence of cell wall. It is a human pathogen causing upper and lower respiratory infections, both in adults and children. However, it is also considered to be implicated in the pathogenesis of several types of extra-respiratory diseases, i...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2019.103863

    authors: Poddighe D

    更新日期:2020-02-01 00:00:00

  • Binding characteristics of Escherichia coli enterotoxin b (STb) to the pig jejunum and partial characterization of the molecule involved.

    abstract::Escherichia coli heat-stable enterotoxin b (STb) causes severe diarrhoea in weaning piglets. STb most probably has to bind to intestinal epithelial cells in order to achieve its effect. Using biotinylated biologically active STb, we developed a semi-quantitative binding assay using indirect fluorescence microscopy. We...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1006/mpat.1997.0193

    authors: Rousset E,Harel J,Dubreuil JD

    更新日期:1998-05-01 00:00:00

  • Apoptosis induced by bacterial pathogens.

    abstract::Programmed cell death is part of normal development and homeostasis. Apoptosis induced by bacteria appears to contribute to infectious diseases. Some bacteria produce toxins to kill host cells by the same pathway, apoptosis, through different mechanisms including pore formation, protein synthesis inhibition or adenyla...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章,评审

    doi:10.1006/mpat.1994.1066

    authors: Chen Y,Zychlinsky A

    更新日期:1994-10-01 00:00:00

  • Gut microbiome-based medical methodologies for early-stage disease prevention.

    abstract::Recent advancements highlight the important role of gut microbiome in human health. However, a variety of endogenous and exogenous factors, such as genes, foods, drugs, environmental pollutions, oxidative stress, etc., may interfere with the gut microbiome in vivo and increase risks of digestive system diseases, cardi...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章,评审

    doi:10.1016/j.micpath.2017.02.024

    authors: Wang JZ,Du WT,Xu YL,Cheng SZ,Liu ZJ

    更新日期:2017-04-01 00:00:00

  • Intercellular adhesion and biocide resistance in nontypeable Haemophilus influenzae biofilms.

    abstract::Respiratory infections caused by nontypeable Haemophilus influenzae (NTHi) are a major medical problem. Evidence suggests that the ability to form biofilms on mucosal surfaces may play a role in NTHi pathogenesis. However, the factors that contribute to NTHi biofilm cohesion remain largely unknown. In this study we in...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2009.01.004

    authors: Izano EA,Shah SM,Kaplan JB

    更新日期:2009-04-01 00:00:00

  • Antibiotic resistance, putative virulence factors and curli fimbrination among Cronobacter species.

    abstract::This study aimed to investigate antibiotic resistance and putative virulence factors among Cronobacter sakazakii isolated from powdered infant formula and other sources. The following 9 cultures (CR1-9) were collected from our culture collection: C. sakazakii and 3 Cronobacter species: C. sakazakii ATCC® 29544™, C. mu...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2019.103665

    authors: Odeyemi OA,Abdullah Sani N

    更新日期:2019-11-01 00:00:00

  • Treponema denticola invasion into human gingival epithelial cells.

    abstract::Host cell invasion is important for periodontal pathogens in evading host defenses and spreading into deeper areas of the periodontal tissue. Treponema denticola has been implicated in a number of potentially pathogenic processes, including periodontal tissue penetration. Here we tested the ability of T. denticola str...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2016.01.010

    authors: Inagaki S,Kimizuka R,Kokubu E,Saito A,Ishihara K

    更新日期:2016-05-01 00:00:00

  • Indole enhances acid resistance in Escherichia coli.

    abstract::As a stationary-phase signal, indole is secreted in large quantities by Escherichia coli on enriched media and has been shown to control several genes; however, its impact on acid resistance remains to be studied in detail. Real-time quantitative reverse transcription-polymerase chain reaction analysis revealed that i...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2010.05.002

    authors: Hirakawa H,Hayashi-Nishino M,Yamaguchi A,Nishino K

    更新日期:2010-09-01 00:00:00

  • Difference of genotypic and phenotypic characteristics and pathogenicity potential of Photobacterium damselae subsp. damselae between clinical and environmental isolates from Japan.

    abstract::Photobacterium damselae subsp. damselae has been known as an opportunistic pathogen in fish and mammals. Human infectious cases are often very serious and occasionally fatal. We previously reportedtwo fatal cases caused by this subspecies where the patients developed multiple organ failure within 20-36 h after the ons...

    journal_title:Microbial pathogenesis

    pub_type: 杂志文章

    doi:10.1016/j.micpath.2008.04.008

    authors: Takahashi H,Miya S,Kimura B,Yamane K,Arakawa Y,Fujii T

    更新日期:2008-08-01 00:00:00