miR-129-5p Inhibits Adipogenesis through Autophagy and May Be a Potential Biomarker for Obesity.

abstract：:A quarter of men with obesity or type 2 diabetes have hypogonadotropic hypogonadism. Animal studies and in vitro data have shown that insulin action and insulin responsiveness in the brain are necessary for the maintenance of the functional integrity of the hypothalamo-hypophyseal-gonadal axis. We conducted a randomiz...

journal_title：International journal of endocrinology

authors： Dhindsa S,Chemitiganti R,Ghanim H,Santiago E,Haider A,Chaar N,Mok M,McKee A,Dandona P

更新日期：2018-10-31 00:00:00

abstract：:Spermatozoa are highly specialized cells that can be easily obtained and purified. Mature spermatozoa are transcriptionally and translationally inactive and incapable of protein synthesis. In addition, spermatozoa contain relatively higher amounts of membrane proteins compared to other cells; therefore, they are very ...

journal_title：International journal of endocrinology

authors： Rahman MS,Lee JS,Kwon WS,Pang MG

更新日期：2013-01-01 00:00:00

abstract：:Purpose. We investigate the usefulness of multimodal assistant systems using a fusion model of preoperative three-dimensional (3D) computed tomography (CT) and magnetic resonance imaging (MRI) along with endoscopy with indocyanine green (ICG) fluorescence in establishing endoscopic endonasal transsphenoidal surgery (E...

journal_title：International journal of endocrinology

authors： Inoue A,Ohnishi T,Kohno S,Nishida N,Nakamura Y,Ohtsuka Y,Matsumoto S,Ohue S

更新日期：2015-01-01 00:00:00

abstract：:Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. However, the effect of puerarin on the process of human osteoblasts ...

journal_title：International journal of endocrinology

authors： Liu LJ,Liu LQ,Bo T,Li SJ,Zhu Z,Cui RR,Mao DA

更新日期：2013-01-01 00:00:00

abstract：Objective:Neuroendocrine neoplasias (NENs) represent a rare and biologically heterogeneous group of malignancies. Treatment of NEN patients remains challenging due to lack of prospective evidence on the choice of ideal therapeutic sequence and therapeutic efficacy in specific individual scenarios. Methods:Clinical dat...

journal_title：International journal of endocrinology

authors： Mayer K,Kiry S,Yordanova A,Ahmadzadehfar H,Gaertner FC,Bundschuh RA,Essler M,Gonzalez-Carmona MA,Strassburg CP,Matthaei H,Lingohr P,Bisht S,Brossart P,Feldmann G

更新日期：2020-01-31 00:00:00

abstract：Background:Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone-binding globulin (SHBG) and albumin. Only 1-2% of nonprotein-bound te...

journal_title：International journal of endocrinology

authors： Antonio L,Pauwels S,Laurent MR,Vanschoubroeck D,Jans I,Billen J,Claessens F,Decallonne B,De Neubourg D,Vermeersch P,Vanderschueren D

更新日期：2018-09-10 00:00:00

abstract：:Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 level in HepG2 cells...

journal_title：International journal of endocrinology

authors： Chai D,Wang G,Zhou Z,Yang H,Yu Z

更新日期：2015-01-01 00:00:00

abstract：:Objective. To explore whether GC (group-specific component) rs17467825, rs4588, and rs7041 polymorphisms are associated with generalized aggressive periodontitis. Methods. This case-control study recruited 372 patients with generalized aggressive periodontitis (group AgP) and 133 periodontal healthy subjects (group HP...

journal_title：International journal of endocrinology

authors： Song W,Wang X,Tian Y,Zhang X,Lu R,Meng H

更新日期：2016-01-01 00:00:00

abstract：:In obese diabetic subjects, a correct life style, including diet and physical activity, is part of a correct intervention protocol. Thus, the aim of this study was to evaluate the effects of aerobic training intervention, based on heart rate at aerobic gas exchange threshold (AerTge), on clinical and physiological par...

journal_title：International journal of endocrinology

authors： Emerenziani GP,Gallotta MC,Meucci M,Di Luigi L,Migliaccio S,Donini LM,Strollo F,Guidetti L

更新日期：2015-01-01 00:00:00

abstract：:Parathyroid glands contain the vitamin D receptor (VDR) and 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24A1), which catalyze the production and degradation of 1,25-dihydroxyvitamin D [1,25(OH)2D], respectively. Previous studies have shown that the serum level of intact parathyroid hormone (iPT...

journal_title：International journal of endocrinology

authors： Jiang Y,Liao L,Li J,Wang L,Xie Z

更新日期：2020-04-09 00:00:00

abstract：:Sex steroid hormones have neuroprotective properties which may be mediated by brain-derived neurotrophic factor (BDNF). This study sought to determine the interactive effects of preadolescent hormone manipulation and BDNF heterozygosity (+/-) on hippocampal NMDA-R expression. Wild-type and BDNF+/- mice were gonadectom...

journal_title：International journal of endocrinology

authors： McCarthny CR,Du X,Wu YC,Hill RA

更新日期：2018-01-31 00:00:00

abstract：:Present therapies to minify hyperglycaemia and insulin resistance mainly target ATP-sensitive K(+) channels (K(ATP)) of pancreatic cells and PPAR-γ to enhance the insulin secretion and potential for GLUT expression, respectively. These current approaches are frequently associated with the various side effects such as ...

journal_title：International journal of endocrinology

authors： Ahmed D,Sharma M

更新日期：2011-01-01 00:00:00

abstract：:Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by differences in fasting non-esterified fatty acid (NEFA) levels and/or NEFA suppression after oral ...

journal_title：International journal of endocrinology

authors： Finucane FM,Sharp SJ,Hatunic M,Sleigh A,De Lucia Rolfe E,Sayer AA,Cooper C,Griffin SJ,Savage DB,Wareham NJ

更新日期：2013-01-01 00:00:00

abstract：:Epidemiological studies have shown an association between short or disrupted sleep and an increased risk for metabolic disorders. To assess a possible causal relationship, we examined the effects of experimental sleep disturbance on glucose regulation in Wistar rats under controlled laboratory conditions. Three groups...

journal_title：International journal of endocrinology

authors： Barf RP,Meerlo P,Scheurink AJ

更新日期：2010-01-01 00:00:00

abstract：:Plasma FGF-23 concentrations and its relationship with calcium-phosphate homeostasis were evaluated in 48 perimenopausal obese women and in 29 nonobese controls. Serum parathyroid hormone, 25-hydroxyvitamin D(3), CTX1, osteocalcin, total calcium, phosphorus, creatinine, and plasma intact FGF-23 concentrations were ass...

journal_title：International journal of endocrinology

authors： Holecki M,Chudek J,Więcek A,Titz-Bober M,Duława J

更新日期：2011-01-01 00:00:00

abstract：:The chemosensitivity of anaplastic thyroid cancer (ATC) to some cytotoxic agents was investigated by the histoculture drug response assay (HDRA). Thirty specimens from 22 patients with ATC were obtained from surgically resected subjects. The drugs tested were paclitaxel (PTX), docetaxel (DOC), adriamycin (ADM), nedapl...

journal_title：International journal of endocrinology

authors： Uruno T,Masaki C,Akaishi J,Matsuzu K,Suzuki A,Ohkuwa K,Shibuya H,Kitagawa W,Nagahama M,Sugino K,Ito K

更新日期：2015-01-01 00:00:00

abstract：:Primary hyperparathyroidism (PHPT) is not an uncommon disease in the western countries. In Thailand, on the contrary, PHPT was a rare condition with various clinical presentations. All 45 PHPT patients who underwent parathyroidectomy at the Department of Surgery, Siriraj Hospital during January 1997 and December 2007 ...

journal_title：International journal of endocrinology

authors： Prasarttong-Osoth P,Wathanaoran P,Imruetaicharoenchoke W,Rojananin S

更新日期：2012-01-01 00:00:00

abstract：Background:The aim was to investigate the amounts of saliva and serum asprosin in order to determine whether it is related to obesity and whether salivary glands synthesize asprosin or not. Methods:A total of 116 underweight, normal weight, overweight, and obese (class I, class II, and class III) volunteers participat...

journal_title：International journal of endocrinology

authors： Ugur K,Aydin S

更新日期：2019-03-27 00:00:00

abstract：:Propylthiouracil- (PTU-) induced hepatotoxicity is rare but potentially lethal with a spectrum of liver injury ranging from asymptomatic elevation of transaminases to fulminant hepatic failure and death. We describe two cases of acute hepatic failure due to PTU that required liver transplantation. Differences in the c...

journal_title：International journal of endocrinology

authors： Carrion AF,Czul F,Arosemena LR,Selvaggi G,Garcia MT,Tekin A,Tzakis AG,Martin P,Ghanta RK

更新日期：2010-01-01 00:00:00

abstract：:Leptin and adiponectin are differentially expressed adipokines in obesity and cardiovascular diseases. Leptin levels are directly associated with adipose tissue mass, while adiponectin levels are downregulated in obesity. Although significantly produced by adipocytes, leptin is also produced by vascular smooth muscle ...

journal_title：International journal of endocrinology

authors： Ghantous CM,Azrak Z,Hanache S,Abou-Kheir W,Zeidan A

更新日期：2015-01-01 00:00:00

abstract：:There is inconsistency among published guidelines for the optimal diagnostic and management pathways for patients with typical (TC) or atypical (AC) pulmonary carcinoid tumours. We conducted a UK-wide clinician survey to assess current practice for the diagnosis, management, and follow-up of patients with TC/AC and de...

journal_title：International journal of endocrinology

authors： Mansoor W,Ferguson S,Ross V,Talbot D

更新日期：2020-02-28 00:00:00

abstract：:A retrospective review of 626 patients with multifocal papillary thyroid carcinoma (PTC) including 147 patients (23.5%) with multifocal papillary thyroid microcarcinoma (PTMC) from a total of 2,536 patients with PTC who visited the Chang Gung Medical Center in Linkou, Taiwan, was performed. A comparison of the clinica...

journal_title：International journal of endocrinology

authors： Ng SC,Kuo SF,Chen ST,Hsueh C,Huang BY,Lin JD

更新日期：2017-01-01 00:00:00

abstract：:Purpose. To evaluate whether inferior rectus muscle (IRM) thickness, the degree of adipose change in the IRM, smoking status, and the previous history of orbital radiotherapy can predict the dose-effect relationship regarding unilateral IRM recession in thyroid eye disease (TED). Methods. Twenty-five patients were ret...

journal_title：International journal of endocrinology

authors： Takahashi Y,Kakizaki H

更新日期：2015-01-01 00:00:00

abstract：:Varicocele in infertile males is associated with Leydig cell dysfunction and hypogonadism. The effect of varicocelectomy on serum testosterone level is not yet established. We analysed 200 heterosexual infertile men diagnosed to have clinical varicocele they were divided into two groups: group 1 (100 men) had microsur...

journal_title：International journal of endocrinology

authors： Sathya Srini V,Belur Veerachari S

更新日期：2011-01-01 00:00:00

abstract：:Purpose. To evaluate the associations between metformin, insulin, statins, and levothyroxine and breast cancer characteristics and outcome. Methods. Retrospective chart review of patients treated in our institute for early estrogen receptor (ER) positive, human epidermal growth factor receptor 2 negative breast cancer...

journal_title：International journal of endocrinology

authors： Goldvaser H,Rizel S,Hendler D,Neiman V,Shepshelovich D,Shochat T,Sulkes A,Brenner B,Yerushalmi R

更新日期：2016-01-01 00:00:00

abstract：:Glucose is the major source of energy for the human brain which in turn uses ketone bodies as a supplement for energy deficit in glucose cell deficiency conditions. Pregnancy complicated by gestational diabetes is a condition associated with significantly increased risk of ketonemia development. The data available pro...

journal_title：International journal of endocrinology

authors： Bronisz A,Ozorowski M,Hagner-Derengowska M

更新日期：2018-06-04 00:00:00

abstract：:Objective. To analyze changes in vital signs (heart rate (HR), systolic (SBP), and diastolic blood pressure (DBP)) during and after intravenous methylprednisolone (IVMP) and any other adverse effects. Methods. Retrospective review of charts of patients who received IVMP as treatment regime for thyroid eye disease. All...

journal_title：International journal of endocrinology

authors： Yong KL,Chng CL,Htoon HM,Lim LH,Seah LL

更新日期：2015-01-01 00:00:00

abstract：:Clinical evidences have highlighted the efficacy of myo-inositol and selenium in the treatment of autoimmune thyroiditis. Aim of this study was to further analyze the role of myo-inositol plus selenium (Myo-Ins-Se) in restoring a normal thyroid function of Hashimoto's patients with subclinical hypothyroidism. Eighty-s...

journal_title：International journal of endocrinology

authors： Nordio M,Basciani S

更新日期：2017-01-01 00:00:00

abstract：Objective:Once-weekly PEGylated recombinant human growth hormone (rhGH) is the sole long-acting GH formulation available currently for pediatric patients with GH deficiency (GHD). The aim of this study was to evaluate the efficacy and safety of PEGylated rhGH therapy compared to daily rhGH therapy in GHD children treat...

journal_title：International journal of endocrinology

authors： Qiao Y,Wang Z,Han J,Li G

更新日期：2019-09-19 00:00:00

abstract：:Thyroid nodules, with their high prevalence in the general population, represent a diagnostic challenge for clinicians. Ultrasound (US), although absolutely reliable in detecting thyroid nodules, is still not accurate enough to differentiate them into benign and malignant. A promising novel modality, US elastography, ...

journal_title：International journal of endocrinology

authors： Cantisani V,Grazhdani H,Drakonaki E,D'Andrea V,Di Segni M,Kaleshi E,Calliada F,Catalano C,Redler A,Brunese L,Drudi FM,Fumarola A,Carbotta G,Frattaroli F,Di Leo N,Ciccariello M,Caratozzolo M,D'Ambrosio F

更新日期：2015-01-01 00:00:00