Effects of Aerobic Exercise Based upon Heart Rate at Aerobic Threshold in Obese Elderly Subjects with Type 2 Diabetes.

Abstract:

:In obese diabetic subjects, a correct life style, including diet and physical activity, is part of a correct intervention protocol. Thus, the aim of this study was to evaluate the effects of aerobic training intervention, based on heart rate at aerobic gas exchange threshold (AerTge), on clinical and physiological parameters in obese elderly subjects with type 2 diabetes (OT2DM). Thirty OT2DM subjects were randomly assigned to an intervention (IG) or control group (CG). The IG performed a supervised aerobic exercise training based on heart rate at AerTge whereas CG maintained their usual lifestyle. Anthropometric measures, blood analysis, peak oxygen consumption ([Formula: see text]), metabolic equivalent (METpeak), work rate (WRpeak), and WRAerTge were assessed at baseline and after intervention. After training, patients enrolled in the IG had significantly higher (P < 0.001) [Formula: see text], METpeak, WRpeak, and WRAerTge and significantly lower (P < 0.005) weight, BMI, %FM, and waist circumference than before intervention. Both IG and CG subjects had lower glycated haemoglobin levels after intervention period. No significant differences were found for all the other parameters between pre- and posttraining and between groups. Aerobic exercise prescription based upon HR at AerTge could be a valuable physical intervention tool to improve the fitness level and metabolic equilibrium in OT2DM patients.

journal_name

Int J Endocrinol

authors

Emerenziani GP,Gallotta MC,Meucci M,Di Luigi L,Migliaccio S,Donini LM,Strollo F,Guidetti L

doi

10.1155/2015/695297

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

695297

eissn

1687-8337

issn

1687-8345

journal_volume

2015

pub_type

杂志文章
  • Autoimmune Diseases in Patients with Cushing's Syndrome after Resolution of Hypercortisolism: Case Reports and Literature Review.

    abstract:Introduction:Cushing's syndrome (CS) is a clinical condition characterized by excessive cortisol production, associated with metabolic complications, such as diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, and cardiovascular diseases. Nowadays, the occurrence of autoimmune diseases in CS have not bee...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2018/1464967

    authors: Petramala L,Olmati F,Conforti MG,Concistré A,Bisogni V,Alfieri N,Iannucci G,de Toma G,Letizia C

    更新日期:2018-12-18 00:00:00

  • Use of PEGylated Recombinant Human Growth Hormone in Chinese Children with Growth Hormone Deficiency: A 24-Month Follow-Up Study.

    abstract:Objective:Once-weekly PEGylated recombinant human growth hormone (rhGH) is the sole long-acting GH formulation available currently for pediatric patients with GH deficiency (GHD). The aim of this study was to evaluate the efficacy and safety of PEGylated rhGH therapy compared to daily rhGH therapy in GHD children treat...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2019/1438723

    authors: Qiao Y,Wang Z,Han J,Li G

    更新日期:2019-09-19 00:00:00

  • Correlation between B-Type Natriuretic Peptide and Functional/Cognitive Parameters in Discharged Congestive Heart Failure Patients.

    abstract::The determination of B-type natriuretic peptides (BNP) may have a role in the diagnosis of heart failure (HF) or guiding HF therapy. This study investigated the role of BNP determination in a cohort of elderly patients admitted to hospital with acute decompensated HF and its correlation with main demographic, clinical...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/239136

    authors: Leto L,Testa M,Feola M

    更新日期:2015-01-01 00:00:00

  • Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals.

    abstract::Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by differences in fasting non-esterified fatty acid (NEFA) levels and/or NEFA suppression after oral ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2013/870487

    authors: Finucane FM,Sharp SJ,Hatunic M,Sleigh A,De Lucia Rolfe E,Sayer AA,Cooper C,Griffin SJ,Savage DB,Wareham NJ

    更新日期:2013-01-01 00:00:00

  • Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model.

    abstract::Low birth weight is associated with reduced bone mass and density in adult life. However, effects of maternal hypoxia (MH) on offspring bone development are not known. Objective. The current study investigated the effects of fetal growth restriction induced by MH during the last half of gestation on bone structure and...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2014/916918

    authors: Lee AM,Morrison JL,Botting KJ,Shandala T,Xian CJ

    更新日期:2014-01-01 00:00:00

  • Melatonin: An Anti-Tumor Agent in Hormone-Dependent Cancers.

    abstract::Melatonin (N-acetyl-5-methoxytryptamine) is a hormone synthesized and secreted by the pineal gland mainly during the night, since light exposure suppresses its production. Initially, an implication of this indoleamine in malignant disease was described in endocrine-responsive breast cancer. Data from several clinical ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2018/3271948

    authors: Menéndez-Menéndez J,Martínez-Campa C

    更新日期:2018-10-02 00:00:00

  • Clinicopathological Characteristics and Prognosis of Papillary Thyroid Carcinoma in Naturally Menopausal Women with Various Durations of Premenarche, Reproductive Periods, and Postmenopausal Stages.

    abstract::Background. Papillary thyroid cancer (PTC) exhibits a higher incidence in women. Due to various ages at menarche and menopause, estrogen levels vary, which may account for the differences in the occurrence, development, and prognosis of female patients with PTC. Objective. The aim of this study was to investigate the ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2017/5702716

    authors: Zhu X,Yu B,Huang YQ,Zhou JN,Ge MH

    更新日期:2017-01-01 00:00:00

  • Hyperoside Alleviates High Glucose-Induced Proliferation of Mesangial Cells through the Inhibition of the ERK/CREB/miRNA-34a Signaling Pathway.

    abstract:Purpose:Hyperoside, a flavonoid isolated from conventional medicinal herbs, has been demonstrated to exert a significant protective effect in diabetic nephropathy. This study aimed to determine the underlying mechanisms, by which hyperoside inhibits high glucose-(HG-) induced proliferation in mouse renal mesangial cell...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2020/1361924

    authors: Zhang L,Dai Q,Hu L,Yu H,Qiu J,Zhou J,Long M,Zhou S,Zhang K

    更新日期:2020-07-21 00:00:00

  • The Impact of Preconceptional Serum TSH Levels between 2.5 and 4.0 mIU/L on Infertile Women Going through Their First IUI Treatment Cycle.

    abstract:Objective:To evaluate the impact of preconceptional serum TSH levels on the clinical outcomes of infertile patients undergoing their first IUI treatment cycle. Method:This was a retrospective study. Euthyroid patients undergoing the first cycle of IUI treatment from Jan 2017 to Aug 2018 were included. The patients wer...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2019/8492904

    authors: Zhang Y,Wu W,Liu Y,Wang X,Jia L

    更新日期:2019-12-18 00:00:00

  • The Prevalence and Associated Risk Factors of Impaired Glucose Regulation in Chinese Adults: A Population-Based Cross-Sectional Study.

    abstract::The goal of this study was to determine the prevalence and associated risk factors of impaired glucose regulation (IGR) in the population of Tongzhou, China, and to provide scientific basis for preventive interventions. In the study, the overall age-standardized prevalence of IGR (16.0%) in Tongzhou residents was high...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/731583

    authors: Zhao D,Wu N,Yang J,Liu S,Zhang N,Wang X,Zhang H

    更新日期:2015-01-01 00:00:00

  • The Clinicopathological Features of BRAF Mutated Papillary Thyroid Cancers in Chinese Patients.

    abstract::The BRAF(V600E) mutation is commonly found in papillary thyroid cancers (PTCs) at different frequencies in different regions. However, the association between the BRAF(V600E) mutation and clinicopathological features in Chinese PTC patients is unknown. A total of 543 Chinese patients with histologically confirmed PTC ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/642046

    authors: Yang LB,Sun LY,Jiang Y,Tang Y,Li ZH,Zhang HY,Bu H,Ye F

    更新日期:2015-01-01 00:00:00

  • Physiological Effect of Ghrelin on Body Systems.

    abstract::Ghrelin is a relatively novel multifaceted hormone that has been found to exert a plethora of physiological effects. In this review, we found/confirmed that ghrelin has effect on all body systems. It induces appetite; promotes the use of carbohydrates as a source of fuel while sparing fat; inhibits lipid oxidation and...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2020/1385138

    authors: Akalu Y,Molla MD,Dessie G,Ayelign B

    更新日期:2020-05-25 00:00:00

  • Iodine Supplementation: Usage "with a Grain of Salt".

    abstract::Iodine supplementation through salt iodization is a worldwide, effective strategy for preventing iodine deficiency-related problems. Its safety and efficacy profile has been extensively investigated, and benefits far outweigh the potential iodine-induced risks. Moreover, iodine supplementation during pregnancy in orde...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2015/312305

    authors: Prete A,Paragliola RM,Corsello SM

    更新日期:2015-01-01 00:00:00

  • Does varicocelectomy improve gonadal function in men with hypogonadism and infertility? Analysis of a prospective study.

    abstract::Varicocele in infertile males is associated with Leydig cell dysfunction and hypogonadism. The effect of varicocelectomy on serum testosterone level is not yet established. We analysed 200 heterosexual infertile men diagnosed to have clinical varicocele they were divided into two groups: group 1 (100 men) had microsur...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2011/916380

    authors: Sathya Srini V,Belur Veerachari S

    更新日期:2011-01-01 00:00:00

  • Factors in Gestational Diabetes Mellitus Predicting the Needs for Insulin Therapy.

    abstract::Objective. To identify factors predicting the need for insulin therapy in pregnancies complicated by gestational diabetes mellitus (GDM). Methods. A total of 1352 patients with GDM diagnosed by the 75-g/2-h oral glucose tolerance test (OGTT) were enrolled in this study. Univariate and multivariate analysis were perfor...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2016/4858976

    authors: Zhang Y,Shao J,Li F,Xu X

    更新日期:2016-01-01 00:00:00

  • Sperm proteomics: road to male fertility and contraception.

    abstract::Spermatozoa are highly specialized cells that can be easily obtained and purified. Mature spermatozoa are transcriptionally and translationally inactive and incapable of protein synthesis. In addition, spermatozoa contain relatively higher amounts of membrane proteins compared to other cells; therefore, they are very ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2013/360986

    authors: Rahman MS,Lee JS,Kwon WS,Pang MG

    更新日期:2013-01-01 00:00:00

  • Thyroid Stimulating Hormone Is Increased in Hypertensive Patients with Obstructive Sleep Apnea.

    abstract::Purpose. To evaluate alteration in serum TSH in hypertensives with OSA and its relation with cardiometabolic risk factors. Methods. 517 hypertensives were cross-sectionally studied. OSA was determined by polysomnography and thyroid function by standard methods. Results. OSA was diagnosed in 373 hypertensives (72.15%)....

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2016/4802720

    authors: Li N,Heizhati M,Sun C,Abulikemu S,Shao L,Yao X,Wang Y,Hong J,Zhou L,Wang L,Zhang Y,Zhang W

    更新日期:2016-01-01 00:00:00

  • Insulin Increases Sestrin 2 Content by Reducing Its Degradation through the PI 3 K/mTOR Signaling Pathway.

    abstract::Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 level in HepG2 cells...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/505849

    authors: Chai D,Wang G,Zhou Z,Yang H,Yu Z

    更新日期:2015-01-01 00:00:00

  • Relationship between Testicular Volume and Conventional or Nonconventional Sperm Parameters.

    abstract::Background. Reduced testicular volume (TV) (<12 cm(3)) is associated with lower testicular function. Several studies explored the conventional sperm parameters (concentration, motility, and morphology) and the endocrine function (gonadotropins and testosterone serum concentrations) in the patients with reduction of TV...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2013/145792

    authors: Condorelli R,Calogero AE,La Vignera S

    更新日期:2013-01-01 00:00:00

  • Stability of miR-126 in Urine and Its Potential as a Biomarker for Renal Endothelial Injury with Diabetic Nephropathy.

    abstract::Background. The purpose of the present study was to assess the feasibility of using miR-126 in the urine as a biomarker for diabetic nephropathy. Methods. miRNAs were extracted from the urine samples of T2DM patients with diabetic nephropathy (DN; n = 92), T2DM without DN (n = 86), and 85 healthy volunteers using quan...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2014/393109

    authors: Liu Y,Gao G,Yang C,Zhou K,Shen B,Liang H,Jiang X

    更新日期:2014-01-01 00:00:00

  • GC Gene Polymorphisms and Vitamin D-Binding Protein Levels Are Related to the Risk of Generalized Aggressive Periodontitis.

    abstract::Objective. To explore whether GC (group-specific component) rs17467825, rs4588, and rs7041 polymorphisms are associated with generalized aggressive periodontitis. Methods. This case-control study recruited 372 patients with generalized aggressive periodontitis (group AgP) and 133 periodontal healthy subjects (group HP...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2016/5141089

    authors: Song W,Wang X,Tian Y,Zhang X,Lu R,Meng H

    更新日期:2016-01-01 00:00:00

  • Exercise for hepatic fat accumulation in type 2 diabetic subjects.

    abstract::Type 2 diabetes is characterized by frequent ectopic fat accumulation in several tissues and organs. In particular, a number of studies showed that these subjects frequently have hepatic fat accumulation, which may play a role in the metabolic abnormalities typical of diabetes and has been also linked to increased ris...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2013/309191

    authors: Bacchi E,Moghetti P

    更新日期:2013-01-01 00:00:00

  • The Association between the Epicardial Adipose Tissue Thickness and Oxidative Stress Parameters in Isolated Metabolic Syndrome Patients: A Multimarker Approach.

    abstract::The risk for cardiovascular diseases and type 2 diabetes mellitus significantly increases in the patient population with metabolic syndrome (MeS). The present study aimed to investigate the association between the epicardial adipose tissue thickness (EATT) and the oxidative stress parameters in MeS patients. The study...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2014/954045

    authors: Demir B,Demir E,Acıksarı G,Uygun T,Utku IK,Gedikbasi A,Caglar IM,Pirhan O,Tureli HO,Oflar E,Ungan İ,Ciftci S,Karakaya O

    更新日期:2014-01-01 00:00:00

  • Pregnancy Ketonemia and Development of the Fetal Central Nervous System.

    abstract::Glucose is the major source of energy for the human brain which in turn uses ketone bodies as a supplement for energy deficit in glucose cell deficiency conditions. Pregnancy complicated by gestational diabetes is a condition associated with significantly increased risk of ketonemia development. The data available pro...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2018/1242901

    authors: Bronisz A,Ozorowski M,Hagner-Derengowska M

    更新日期:2018-06-04 00:00:00

  • Increased Circulating Chemerin in Relation to Chronic Microvascular Complications in Patients with Type 2 Diabetes.

    abstract:Objective:Type 2 diabetes (T2DM) is a global epidemic and increases mortality due to its vascular complications. Chemerin has been found to exert a major role in glucose and lipid metabolism. The aim of this study was to explore the correlation between plasma chemerin levels and microangiopathy in patients with T2DM. ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2019/8693516

    authors: Gu P,Wang W,Yao Y,Xu Y,Wang L,Zang P,Ma J,Yang C,Liang J,Lu B,Shao J

    更新日期:2019-07-16 00:00:00

  • The Age-Specific Association of Waist Circumference and Risk of Chronic Kidney Disease in Patients with Type 2 Diabetes Mellitus in Shandong, China.

    abstract::Objective. To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). Design. Cross-sectional evaluation of the effect of anthropometric ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/715871

    authors: Xu L,Yu W,Huang P,Li C,Li Y,Wang M,Xu Q,Wang J,Zheng C,Qu B,Zhao Y,Niu M,Wang O,Gong F

    更新日期:2015-01-01 00:00:00

  • Diagnostic and Management Pathways for Pulmonary Carcinoid Tumours in the United Kingdom: Results from the National Lung Neuroendocrine Tumour Pathway Project.

    abstract::There is inconsistency among published guidelines for the optimal diagnostic and management pathways for patients with typical (TC) or atypical (AC) pulmonary carcinoid tumours. We conducted a UK-wide clinician survey to assess current practice for the diagnosis, management, and follow-up of patients with TC/AC and de...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2020/9287536

    authors: Mansoor W,Ferguson S,Ross V,Talbot D

    更新日期:2020-02-28 00:00:00

  • Effects of growth hormone replacement therapy on bone mineral density in growth hormone deficient adults: a meta-analysis.

    abstract::Objectives. Growth hormone deficiency patients exhibited reduced bone mineral density compared with healthy controls, but previous researches demonstrated uncertainty about the effect of growth hormone replacement therapy on bone in growth hormone deficient adults. The aim of this study was to determine whether the gr...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2013/216107

    authors: Xue P,Wang Y,Yang J,Li Y

    更新日期:2013-01-01 00:00:00

  • Differential Role of Leptin and Adiponectin in Cardiovascular System.

    abstract::Leptin and adiponectin are differentially expressed adipokines in obesity and cardiovascular diseases. Leptin levels are directly associated with adipose tissue mass, while adiponectin levels are downregulated in obesity. Although significantly produced by adipocytes, leptin is also produced by vascular smooth muscle ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2015/534320

    authors: Ghantous CM,Azrak Z,Hanache S,Abou-Kheir W,Zeidan A

    更新日期:2015-01-01 00:00:00

  • Comparison of ox-LDL Levels in Diabetic Patients with Normo-, Micro-, and Macroalbuminuria with Their First Degree Relatives and the Healthy Control Group.

    abstract::Oxidized low density lipoprotein (ox-LDL) is a product of oxidative stress. In this cross-sectional study, we compared the ox-LDL concentrations in diabetic patients with normoalbuminuria (n = 28), microalbuminuria (n = 28), and macroalbuminuria (n = 28) with their first degree relatives (n = 28) and healthy control p...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2012/167154

    authors: Behzadi P,Torabi F,Amini M,Aminorroaya A

    更新日期:2012-01-01 00:00:00