Abstract:
:Objective. To identify factors predicting the need for insulin therapy in pregnancies complicated by gestational diabetes mellitus (GDM). Methods. A total of 1352 patients with GDM diagnosed by the 75-g/2-h oral glucose tolerance test (OGTT) were enrolled in this study. Univariate and multivariate analysis were performed; receiver operating characteristics (ROC) were also drawn. Results. There was a significant difference in factors such as maternal age, pregestational BMI, first visit SBP, first visit DBP, FBG of first visit, FBG at time of OGTT, 75-g OGTT glucose value (fasting, after 1 h and 2 h), and serum HbA1c level at diagnosis between patients with insulin therapy and patients with medical nutrition therapy (MNT) alone. Multivariate analysis showed that higher FBG at time of OGTT, first 75 g OGTT 2 h plasma glucose, and HbA1c concentration at diagnosis lead to more likely need of insulin therapy. Conclusion. The probability of insulin therapy can be estimated in pregnant women with GDM based on fasting and 2 h glucose values during OGTT and HbA1c value at diagnosis of GDM.
journal_name
Int J Endocrinoljournal_title
International journal of endocrinologyauthors
Zhang Y,Shao J,Li F,Xu Xdoi
10.1155/2016/4858976subject
Has Abstractpub_date
2016-01-01 00:00:00pages
4858976eissn
1687-8337issn
1687-8345journal_volume
2016pub_type
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journal_title:International journal of endocrinology
pub_type: 杂志文章
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更新日期:2020-04-27 00:00:00
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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更新日期:2010-01-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1155/2014/589587
更新日期:2014-01-01 00:00:00