Systemic Therapy of Neuroendocrine Neoplasia: Single Center Experience from a Cohort of 110 Consecutive Cases.

abstract：:Prostate cancer (PCa) is the most common malignancy in elderly men. The progressive ageing of the world male population will further increase the need for tailored assessment and treatment of PCa patients. The determinant role of androgens and sexual hormones for PCa growth and progression has been established. Howeve...

journal_title：International journal of endocrinology

authors： Gacci M,Baldi E,Tamburrino L,Detti B,Livi L,De Nunzio C,Tubaro A,Gravas S,Carini M,Serni S

更新日期：2014-01-01 00:00:00

abstract：:This study investigated potential markers for predicting nonfunctioning pituitary adenoma (NFPA) invasion and recurrence by high-throughput tissue microarray analyses. We retrospectively studied two groups of patients: 60 nonrecurrent NFPA cases that included noninvasion and invasion subtypes and 43 recurrent cases th...

journal_title：International journal of endocrinology

authors： Yao X,Zhang Y,Wu L,Cheng R,Li C,Qu C,Ji H

更新日期：2019-05-16 00:00:00

abstract：Objective:We sought to evaluate the association between femoral neck (FN) and lumbar spine (LS) bone mineral densities (BMDs) with severity of chronic kidney disease (CKD) and prevalence of osteopenia or osteoporosis (OP) among the CKD group. Methods:Cross-sectional data from 11050 participants aged ≥20 years from the...

journal_title：International journal of endocrinology

authors： Huang JF,Zheng XQ,Sun XL,Zhou X,Liu J,Li YM,Wang XY,Zhang XL,Wu AM

更新日期：2020-10-26 00:00:00

abstract：Objective:To evaluate the impact of preconceptional serum TSH levels on the clinical outcomes of infertile patients undergoing their first IUI treatment cycle. Method:This was a retrospective study. Euthyroid patients undergoing the first cycle of IUI treatment from Jan 2017 to Aug 2018 were included. The patients wer...

journal_title：International journal of endocrinology

authors： Zhang Y,Wu W,Liu Y,Wang X,Jia L

更新日期：2019-12-18 00:00:00

abstract：OBJECTIVE:We aimed to explore whether squamous cell carcinoma antigen (SCC), cytokeratin 19 fragment (Cyfra21-1), neuron-specific enolase (NSE), and carcinoembryonic antigen (CEA) are elevated in diabetic nephropathy (DN) and the association between urinary albumin-to-creatinine ratio (UACR) and tumor markers in diabet...

journal_title：International journal of endocrinology

authors： Chen J,Tao F,Zhang B,Chen Q,Qiu Y,Luo Q,Gen Y,Meng J,Zhang J,Lu H

更新日期：2017-01-01 00:00:00

abstract：:Aim. To examine the relationship between plasma 25-hydroxyvitamin D (25(OH)D) levels and blood hemoglobin A1c (HbA1c) levels in diabetic patients at various stages of chronic kidney disease (CKD). Methods. We screened for data collected between 2003 and 2012. The correlation between 25(OH)D and HbA1c levels was studie...

journal_title：International journal of endocrinology

authors： Kajbaf F,Mentaverri R,Diouf M,Fournier A,Kamel S,Lalau JD

更新日期：2014-01-01 00:00:00

abstract：:Diabetes is a lifelong course disease, so insulin treatment has to be effective and safe, and patients should be satisfied with it. We aimed to compare efficacy, safety, and quality of treatment satisfaction of human and premixed analogue insulin among 3264 patients (53.58% women) with type 2 diabetes mellitus (T2DM) ...

journal_title：International journal of endocrinology

authors： Nabrdalik K,Kwiendacz H,Sawczyn T,Tomasik A,Kukla M,Masierek M,Gumprecht J

更新日期：2018-03-05 00:00:00

abstract：:The study aimed at assessing the potential use of lower total and HMW adiponectin levels for predicting cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). Concentrations of total adiponectin or high molecular weight (HMW) adiponectin decrease in association with the development of metabolic dysfunct...

journal_title：International journal of endocrinology

authors： Horáková D,Azeem K,Benešová R,Pastucha D,Horák V,Dumbrovská L,Martínek A,Novotný D,Švagera Z,Hobzová M,Galuszková D,Janout V,Doněvská S,Vrbková J,Kollárová H

更新日期：2015-01-01 00:00:00

abstract：:The hypothalamus is an essential relay in the neural circuitry underlying energy metabolism that needs to continually adapt to changes in the energetic environment. The neuroendocrine control of food intake and energy expenditure is associated with, and likely dependent upon, hypothalamic plasticity. Severe disturbanc...

journal_title：International journal of endocrinology

authors： Stranahan AM,Martin B,Chadwick W,Park SS,Wang L,Becker KG,Woodiii WH,Zhang Y,Maudsley S

更新日期：2012-01-01 00:00:00

abstract：:Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) in thyroid fine needle aspiration (FNA) is a challenging category. The malignancy risk is different by multiple factors and subsequent management strategy is inconclusive. Therefore, we analyzed the malignancy risk of AUS/FLU...

journal_title：International journal of endocrinology

authors： Hong SH,Lee H,Cho MS,Lee JE,Sung YA,Hong YS

更新日期：2018-07-30 00:00:00

abstract：:Objective. The follow-up of GH levels in short-stature children with pituitary hyperplasia secondary to primary hypothyroidism (PPH) is reported in a few cases. We aimed to observe changes in GH secretion in short-stature children with PPH. Methods. A total of 11 short-stature children with PPH accompanied by low GH l...

journal_title：International journal of endocrinology

authors： Liu M,Hu Y,Li G,Hu W

更新日期：2015-01-01 00:00:00

abstract：:The 5-alpha-reductase type 2 deficiency (5ARD2) is an autosomal recessive condition associated with impairment in the conversion of testosterone to dihydrotestosterone. This condition leads to undervirilisation in 46,XY individuals. To date, there have been more than 100 variations identified in the gene responsible f...

journal_title：International journal of endocrinology

authors： Marzuki NS,Idris FP,Kartapradja HD,Harahap AR,Batubara JRL

更新日期：2019-12-01 00:00:00

abstract：:A considerable increase in endocrine abnormalities has been reported over the last few decades worldwide. A growing exposure to endocrine-disrupting chemicals (EDCs) can be one of the causes of endocrine disorders in populations, and these disorders are not only restricted to the metabolic hormone system but can also ...

journal_title：International journal of endocrinology

authors： de Oliveira M,Rodrigues BM,Olimpio RMC,Graceli JB,Gonçalves BM,Costa SMB,da Silva TM,De Sibio MT,Moretto FCF,Mathias LS,Cardoso DBM,Tilli HP,Freitas-Lima LC,Nogueira CR

更新日期：2019-04-17 00:00:00

abstract：:The complementary role of hyperglycemia and p27(kip1) suppression on islet beta cell regeneration was investigated in a syngeneic mouse model. p27(kip1) gene silencing was performed by infecting islets of C57BL/6 with shRNA lentiviral particles. At 54 hours after viral infection, p27(kip1) protein content in cultured ...

journal_title：International journal of endocrinology

authors： Chen ST,Fu SH,Hsu S,Huang YY,Hsu BR

更新日期：2012-01-01 00:00:00

abstract：:Present therapies to minify hyperglycaemia and insulin resistance mainly target ATP-sensitive K(+) channels (K(ATP)) of pancreatic cells and PPAR-γ to enhance the insulin secretion and potential for GLUT expression, respectively. These current approaches are frequently associated with the various side effects such as ...

journal_title：International journal of endocrinology

authors： Ahmed D,Sharma M

更新日期：2011-01-01 00:00:00

abstract：:The aim of this review was to summarize current knowledge on the correlation between depressive symptoms with a syndrome called partial androgen deficiency of the aging male (PADAM) and on the potential benefits of testosterone (T) treatment on mood. Despite, the causative nature of the relationship between low T leve...

journal_title：International journal of endocrinology

authors： Amore M,Innamorati M,Costi S,Sher L,Girardi P,Pompili M

更新日期：2012-01-01 00:00:00

abstract：Background:Currently, energy obtained from hypercaloric diets has been part of the obesity and type 2 diabetes mellitus (T2DM) epidemics from childhood to old age. Treatment alternatives have been sought from plants, minerals, and trace elements with metabolic effects. Vanadyl sulfate (VS) has been investigated as a hy...

journal_title：International journal of endocrinology

authors： Ortega-Pacheco D,Jiménez-Pérez MM,Serafín-López J,Juárez-Rojas JG,Ruiz-García A,Pacheco-García U

更新日期：2018-12-25 00:00:00

abstract：Objective:To evaluate the effectiveness and safety of coenzyme Q10 for patients with type 2 diabetes mellitus (T2DM). Methods:Data from randomized controlled trials were obtained to assess the effects of coenzyme Q10 versus placebo or western medicine on patients with T2DM. The study's registration number is CRD420180...

journal_title：International journal of endocrinology

authors： Zhang SY,Yang KL,Zeng LT,Wu XH,Huang HY

更新日期：2018-09-16 00:00:00

abstract：:Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. Cancer cells are well known to display an enhanced sugar uptake and consumption. In fact, sugar transporters ar...

journal_title：International journal of endocrinology

authors： Calvo MB,Figueroa A,Pulido EG,Campelo RG,Aparicio LA

更新日期：2010-01-01 00:00:00

abstract：:Background. Papillary thyroid cancer (PTC) exhibits a higher incidence in women. Due to various ages at menarche and menopause, estrogen levels vary, which may account for the differences in the occurrence, development, and prognosis of female patients with PTC. Objective. The aim of this study was to investigate the ...

journal_title：International journal of endocrinology

authors： Zhu X,Yu B,Huang YQ,Zhou JN,Ge MH

更新日期：2017-01-01 00:00:00

abstract：:With the deepening of the researches on uric acid, especially in the study of metabolic diseases, uric acid has been found to be closely related to obesity, metabolic syndrome, nonalcoholic fatty liver disease, diabetes, and other metabolic diseases. Uric acid causes a series of pathophysiological changes through infl...

journal_title：International journal of endocrinology

authors： Xiong Q,Liu J,Xu Y

更新日期：2019-10-13 00:00:00

abstract：Objective:To identify the clinicopathological features correlated to lymph node metastasis (LNM) in patients with papillary thyroid microcarcinoma (PTMC). Methods:Clinical data of 785 PTMC patients who underwent surgical treatment at the Lishui Municipal Central Hospital from September 2008 to December 2017 were retro...

journal_title：International journal of endocrinology

authors： Cheng F,Chen Y,Zhu L,Zhou B,Xu Y,Chen Y,Wen L,Chen S

更新日期：2019-01-15 00:00:00

abstract：:Low birth weight is associated with reduced bone mass and density in adult life. However, effects of maternal hypoxia (MH) on offspring bone development are not known. Objective. The current study investigated the effects of fetal growth restriction induced by MH during the last half of gestation on bone structure and...

journal_title：International journal of endocrinology

authors： Lee AM,Morrison JL,Botting KJ,Shandala T,Xian CJ

更新日期：2014-01-01 00:00:00

abstract：:Sunlight-induced vitamin D, synthesis in the skin is the major source of vitamin D, but data on the relationship of sun-related behaviour with vitamin D and parathyroid hormone (PTH) levels are relatively sparse. We evaluated whether habitual sun exposure is associated with 25-hydroxyvitamin D (25[OH]D) and PTH levels...

journal_title：International journal of endocrinology

authors： Pilz S,Kienreich K,Stückler D,Meinitzer A,Tomaschitz A

更新日期：2012-01-01 00:00:00

abstract：:Whether serum magnesium deficiency is independently associated with the prevalence of microalbuminuria is still unclear. The objective of the present study was to elucidate the association between serum magnesium and microalbuminuria in diabetic patients. A cross-sectional study was conducted in 1829 diabetic subjects...

journal_title：International journal of endocrinology

authors： Xu B,Sun J,Deng X,Huang X,Sun W,Xu Y,Xu M,Lu J,Bi Y

更新日期：2013-01-01 00:00:00

abstract：:Objective. To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). Design. Cross-sectional evaluation of the effect of anthropometric ...

journal_title：International journal of endocrinology

authors： Xu L,Yu W,Huang P,Li C,Li Y,Wang M,Xu Q,Wang J,Zheng C,Qu B,Zhao Y,Niu M,Wang O,Gong F

更新日期：2015-01-01 00:00:00

abstract：:The BRAF(V600E) mutation is commonly found in papillary thyroid cancers (PTCs) at different frequencies in different regions. However, the association between the BRAF(V600E) mutation and clinicopathological features in Chinese PTC patients is unknown. A total of 543 Chinese patients with histologically confirmed PTC ...

journal_title：International journal of endocrinology

authors： Yang LB,Sun LY,Jiang Y,Tang Y,Li ZH,Zhang HY,Bu H,Ye F

更新日期：2015-01-01 00:00:00

abstract：:Purpose. To evaluate alteration in serum TSH in hypertensives with OSA and its relation with cardiometabolic risk factors. Methods. 517 hypertensives were cross-sectionally studied. OSA was determined by polysomnography and thyroid function by standard methods. Results. OSA was diagnosed in 373 hypertensives (72.15%)....

journal_title：International journal of endocrinology

authors： Li N,Heizhati M,Sun C,Abulikemu S,Shao L,Yao X,Wang Y,Hong J,Zhou L,Wang L,Zhang Y,Zhang W

更新日期：2016-01-01 00:00:00

abstract：:Peripheral neuropathy (PN) is a primary complication of type 2 diabetes mellitus (T2DM) and a direct manifestation of vitamin B12 deficiency. Examining the effects of metformin use on PN status became imperative following clinical studies that showed the vitamin B12-lowering effect of the medication. The complexity of...

journal_title：International journal of endocrinology

authors： Ahmed MA,Muntingh GL,Rheeder P

更新日期：2017-01-01 00:00:00

abstract：:Background. Reduced testicular volume (TV) (<12 cm(3)) is associated with lower testicular function. Several studies explored the conventional sperm parameters (concentration, motility, and morphology) and the endocrine function (gonadotropins and testosterone serum concentrations) in the patients with reduction of TV...

journal_title：International journal of endocrinology

authors： Condorelli R,Calogero AE,La Vignera S

更新日期：2013-01-01 00:00:00