MicroRNA and Microvascular Complications of Diabetes.

abstract：:Islet cell transplantation is a promising beta cell replacement therapy for patients with brittle type 1 diabetes as well as refractory chronic pancreatitis. Despite the vast advancements made in this field, challenges still remain in achieving high frequency and long-term successful transplant outcomes. Here we revie...

journal_title：International journal of endocrinology

authors： Kanak MA,Takita M,Kunnathodi F,Lawrence MC,Levy MF,Naziruddin B

更新日期：2014-01-01 00:00:00

abstract：Objective:To evaluate the effectiveness and safety of coenzyme Q10 for patients with type 2 diabetes mellitus (T2DM). Methods:Data from randomized controlled trials were obtained to assess the effects of coenzyme Q10 versus placebo or western medicine on patients with T2DM. The study's registration number is CRD420180...

journal_title：International journal of endocrinology

authors： Zhang SY,Yang KL,Zeng LT,Wu XH,Huang HY

更新日期：2018-09-16 00:00:00

abstract：Background:Little information is available on the association between parents' metabolic syndrome (MetS) and adolescent offspring's obesity in Korea. The aim of our study is to determine the association between parent's metabolic syndrome and offspring's obesity. Methods:The study data were obtained from the Korean Na...

journal_title：International journal of endocrinology

authors： Lee NY,Han K,Lee Y,Kim S,Lee S,Choi Y,Ahn MB,Kim SH,Cho WK,Cho KS,Jung MH,Park YG,Suh BK

更新日期：2020-10-30 00:00:00

abstract：:Thyroid cancer is the most common endocrine malignancy, and its incidence has increased rapidly in recent decades worldwide. Papillary thyroid cancer (PTC) is the most common type of all thyroid cancers. The molecular mechanisms underlying the disease still need to be further investigated. Long noncoding RNAs (lncRNAs...

journal_title：International journal of endocrinology

authors： Choy M,Guo Y,Li H,Wei G,Ye R,Liang W,Xiao H,Li Y,Guan H

更新日期：2019-04-07 00:00:00

abstract：:To investigate effects of long-term testosterone (T) therapy in obese men with T deficiency (TD) and type 2 diabetes mellitus (T2DM), data were collected from two observational, prospective, and cumulative registry studies of 561 men with TD receiving T therapy for up to 6 years. A subgroup of obese hypogonadal men wi...

journal_title：International journal of endocrinology

authors： Haider A,Yassin A,Doros G,Saad F

更新日期：2014-01-01 00:00:00

abstract：:Purpose. To evaluate alteration in serum TSH in hypertensives with OSA and its relation with cardiometabolic risk factors. Methods. 517 hypertensives were cross-sectionally studied. OSA was determined by polysomnography and thyroid function by standard methods. Results. OSA was diagnosed in 373 hypertensives (72.15%)....

journal_title：International journal of endocrinology

authors： Li N,Heizhati M,Sun C,Abulikemu S,Shao L,Yao X,Wang Y,Hong J,Zhou L,Wang L,Zhang Y,Zhang W

更新日期：2016-01-01 00:00:00

abstract：Background:Gynecomastia (GM) is a benign enlargement of male breast due to glandular tissue proliferation. GM is a symptom of systemic or local hormonal disturbances, which could be associated with functional changes or pathological conditions. However, the long-lasting steroid imbalance in men with GM might exert nega...

journal_title：International journal of endocrinology

authors： Robeva R,Elenkova A,Zacharieva S

更新日期：2019-10-03 00:00:00

abstract：:Objective. Patients with more than two spontaneous pregnancy losses are diagnosed with recurrent pregnancy loss. The aim of this study was to evaluate the IR (insulin resistance) in patients with idiopathic recurrent pregnancy loss. Material and Method. A single center, case control study was performed on one hundred ...

journal_title：International journal of endocrinology

authors： Ispasoiu CA,Chicea R,Stamatian FV,Ispasoiu F

更新日期：2013-01-01 00:00:00

abstract：:The role of angiogenesis in pituitary tumor development has been questioned, as pituitary tumors have been usually found to be less vascularized than the normal pituitary tissue. Nevertheless, a significantly higher degree of vasculature has been shown in invasive or macropituitary prolactinomas when compared to nonin...

journal_title：International journal of endocrinology

authors： Cristina C,Luque GM,Demarchi G,Lopez Vicchi F,Zubeldia-Brenner L,Perez Millan MI,Perrone S,Ornstein AM,Lacau-Mengido IM,Berner SI,Becu-Villalobos D

更新日期：2014-01-01 00:00:00

abstract：:A considerable increase in endocrine abnormalities has been reported over the last few decades worldwide. A growing exposure to endocrine-disrupting chemicals (EDCs) can be one of the causes of endocrine disorders in populations, and these disorders are not only restricted to the metabolic hormone system but can also ...

journal_title：International journal of endocrinology

authors： de Oliveira M,Rodrigues BM,Olimpio RMC,Graceli JB,Gonçalves BM,Costa SMB,da Silva TM,De Sibio MT,Moretto FCF,Mathias LS,Cardoso DBM,Tilli HP,Freitas-Lima LC,Nogueira CR

更新日期：2019-04-17 00:00:00

abstract：:In the present study we evaluated in vivo and in vitro effects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin, β -catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents, bank voles. We found that in bank vole testes expression and dist...

journal_title：International journal of endocrinology

authors： Hejmej A,Kotula-Balak M,Chojnacka K,Kuras P,Lydka-Zarzycka M,Bilinska B

更新日期：2013-01-01 00:00:00

abstract：:Leptin and adiponectin are differentially expressed adipokines in obesity and cardiovascular diseases. Leptin levels are directly associated with adipose tissue mass, while adiponectin levels are downregulated in obesity. Although significantly produced by adipocytes, leptin is also produced by vascular smooth muscle ...

journal_title：International journal of endocrinology

authors： Ghantous CM,Azrak Z,Hanache S,Abou-Kheir W,Zeidan A

更新日期：2015-01-01 00:00:00

abstract：:Stevia rebaudiana (Bert.) Bertoni besides being a source of noncaloric sweeteners is also an important source of bioactive molecules. Many plant extracts, mostly obtained with ethyl acetate solvent, are rich in polyphenol compounds that present insulinotropic effects. To investigate whether the nonsweetener fraction, ...

journal_title：International journal of endocrinology

authors： Piovan S,Pavanello A,Peixoto GML,Matiusso CCI,de Moraes AMP,Martins IP,Malta A,Palma-Rigo K,da Silva Franco CC,Milani PG,Dacome AS,da Costa SC,de Freitas Mathias PC,Mareze-Costa CE

更新日期：2018-04-29 00:00:00

abstract：:Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. However, the effect of puerarin on the process of human osteoblasts ...

journal_title：International journal of endocrinology

authors： Liu LJ,Liu LQ,Bo T,Li SJ,Zhu Z,Cui RR,Mao DA

更新日期：2013-01-01 00:00:00

abstract：:Aims. There are two phases of insulin secretion, the first (FPIS) and second phase (SPIS). In this study, we built equations to predict FPIS with metabolic syndrome (MetS) components and fasting plasma insulin (FPI). Methods. Totally, 186 participants were enrolled. 75% of participants were randomly selected as the st...

journal_title：International journal of endocrinology

authors： Lin JD,Hsu CH,Liang YJ,Lian WC,Hsieh CH,Wu CZ,Pei D,Chen YL

更新日期：2015-01-01 00:00:00

abstract：Purpose:Hyperoside, a flavonoid isolated from conventional medicinal herbs, has been demonstrated to exert a significant protective effect in diabetic nephropathy. This study aimed to determine the underlying mechanisms, by which hyperoside inhibits high glucose-(HG-) induced proliferation in mouse renal mesangial cell...

journal_title：International journal of endocrinology

authors： Zhang L,Dai Q,Hu L,Yu H,Qiu J,Zhou J,Long M,Zhou S,Zhang K

更新日期：2020-07-21 00:00:00

abstract：:Background. Papillary thyroid cancer (PTC) exhibits a higher incidence in women. Due to various ages at menarche and menopause, estrogen levels vary, which may account for the differences in the occurrence, development, and prognosis of female patients with PTC. Objective. The aim of this study was to investigate the ...

journal_title：International journal of endocrinology

authors： Zhu X,Yu B,Huang YQ,Zhou JN,Ge MH

更新日期：2017-01-01 00:00:00

abstract：:This study investigated potential markers for predicting nonfunctioning pituitary adenoma (NFPA) invasion and recurrence by high-throughput tissue microarray analyses. We retrospectively studied two groups of patients: 60 nonrecurrent NFPA cases that included noninvasion and invasion subtypes and 43 recurrent cases th...

journal_title：International journal of endocrinology

authors： Yao X,Zhang Y,Wu L,Cheng R,Li C,Qu C,Ji H

更新日期：2019-05-16 00:00:00

abstract：:Propylthiouracil- (PTU-) induced hepatotoxicity is rare but potentially lethal with a spectrum of liver injury ranging from asymptomatic elevation of transaminases to fulminant hepatic failure and death. We describe two cases of acute hepatic failure due to PTU that required liver transplantation. Differences in the c...

journal_title：International journal of endocrinology

authors： Carrion AF,Czul F,Arosemena LR,Selvaggi G,Garcia MT,Tekin A,Tzakis AG,Martin P,Ghanta RK

更新日期：2010-01-01 00:00:00

abstract：:Background. Pediatric CAH patients have an increased risk of cardiovascular disease, and it remains unknown if genetic predisposition is a contributing factor. Glucocorticoid receptor gene (NR3C1) polymorphisms are associated with an adverse metabolic profile. Our aim was to analyze the association between the NR3C1 p...

journal_title：International journal of endocrinology

authors： Moreira RP,Gomes LG,Madureira G,Mendonca BB,Bachega TA

更新日期：2014-01-01 00:00:00

abstract：Objectives:To compare the predictive ability of six anthropometric indices for identification of metabolic syndrome (MetS) and to determine their optimal cut-off points among Chinese adults. Methods:A total of 59,029 participants were enrolled. Body mass index (BMI), waist circumference (WC), waist-to-height ratio (WH...

journal_title：International journal of endocrinology

authors： Zhang J,Zhu W,Qiu L,Huang L,Fang L

更新日期：2018-09-17 00:00:00

abstract：Objective:Many patients with diabetes opt to fast for lab tests, especially for lipid profiles, thus missing breakfast. In parallel, recent studies and international guidelines have indicated that routine fasting for lipid panels may not be necessary. Missing breakfast while fasting for lab tests may invoke hypoglycemi...

journal_title：International journal of endocrinology

authors： Aldasouqi S,Mora S,Bhalla G,Kakumanu N,Corser W,Abela G,Dlewati M,Estrada K,Almounajed A,Tabbaa T,Hammoud J,Newkirk C

更新日期：2018-10-24 00:00:00

abstract：:Background. Management of thyroid nodules with benign aspirates following atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) is not well established. We reviewed the risk of malignancy and the role of ultrasound (US) features among thyroid nodules with benign results followin...

journal_title：International journal of endocrinology

authors： Kim GR,Yoon JH,Kim EK,Moon HJ,Kwak JY

更新日期：2014-01-01 00:00:00

abstract：:Pancreatic beta-cells, which secrete the hormone insulin, are the key arbiters of glucose homeostasis. Defective beta-cell numbers and/or function underlie essentially all major forms of diabetes and must be restored if diabetes is to be cured. Thus, the identification of the molecular regulators of beta-cell mass and...

journal_title：International journal of endocrinology

authors： Tarabra E,Pelengaris S,Khan M

更新日期：2012-01-01 00:00:00

abstract：:Objective. To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). Design. Cross-sectional evaluation of the effect of anthropometric ...

journal_title：International journal of endocrinology

authors： Xu L,Yu W,Huang P,Li C,Li Y,Wang M,Xu Q,Wang J,Zheng C,Qu B,Zhao Y,Niu M,Wang O,Gong F

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2014/690783.]. ...

journal_title：International journal of endocrinology

authors： Napoli N,Strollo R,Paladini A,Briganti SI,Pozzilli P,Epstein S

更新日期：2017-01-01 00:00:00

abstract：Background:Gonadal injury following chemotherapy is of increasing importance with the continuous improvement of survival rates. The protection of gonadotropin hormone antagonist (GnRHant) in long-term adult survivors of adolescent cancers and some autoimmune diseases has not yet been evaluated. Methods:The present stu...

journal_title：International journal of endocrinology

authors： Xie R,Chen L,Wu H,Chen T,Wang F,Chen X,Sun H,Li X

更新日期：2018-06-10 00:00:00

abstract：Introduction:Cushing's syndrome (CS) is a clinical condition characterized by excessive cortisol production, associated with metabolic complications, such as diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, and cardiovascular diseases. Nowadays, the occurrence of autoimmune diseases in CS have not bee...

journal_title：International journal of endocrinology

authors： Petramala L,Olmati F,Conforti MG,Concistré A,Bisogni V,Alfieri N,Iannucci G,de Toma G,Letizia C

更新日期：2018-12-18 00:00:00

abstract：:Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) in thyroid fine needle aspiration (FNA) is a challenging category. The malignancy risk is different by multiple factors and subsequent management strategy is inconclusive. Therefore, we analyzed the malignancy risk of AUS/FLU...

journal_title：International journal of endocrinology

authors： Hong SH,Lee H,Cho MS,Lee JE,Sung YA,Hong YS

更新日期：2018-07-30 00:00:00

abstract：:Endocannabinoids and their G-protein coupled receptors (GPCR) are a current research focus in the area of obesity due to the system's role in food intake and glucose and lipid metabolism. Importantly, overweight and obese individuals often have higher circulating levels of the arachidonic acid-derived endocannabinoids...

journal_title：International journal of endocrinology

authors： Naughton SS,Mathai ML,Hryciw DH,McAinch AJ

更新日期：2013-01-01 00:00:00