Effects of long-term testosterone therapy on patients with "diabesity": results of observational studies of pooled analyses in obese hypogonadal men with type 2 diabetes.

abstract：:Spermatozoa are highly specialized cells that can be easily obtained and purified. Mature spermatozoa are transcriptionally and translationally inactive and incapable of protein synthesis. In addition, spermatozoa contain relatively higher amounts of membrane proteins compared to other cells; therefore, they are very ...

journal_title：International journal of endocrinology

authors： Rahman MS,Lee JS,Kwon WS,Pang MG

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Evidence on the association between subclinical thyroid dysfunction and the risk of cardiovascular outcomes are conflicting. METHODS AND RESULTS:PubMed, EMbase, Web of Science, Cochrane Library, and China Biology Medicine (CBM) databases were searched from inception to July 10, 2016. A total of 16 studies w...

journal_title：International journal of endocrinology

authors： Sun J,Yao L,Fang Y,Yang R,Chen Y,Yang K,Tian L

更新日期：2017-01-01 00:00:00

abstract：:The role of angiogenesis in pituitary tumor development has been questioned, as pituitary tumors have been usually found to be less vascularized than the normal pituitary tissue. Nevertheless, a significantly higher degree of vasculature has been shown in invasive or macropituitary prolactinomas when compared to nonin...

journal_title：International journal of endocrinology

authors： Cristina C,Luque GM,Demarchi G,Lopez Vicchi F,Zubeldia-Brenner L,Perez Millan MI,Perrone S,Ornstein AM,Lacau-Mengido IM,Berner SI,Becu-Villalobos D

更新日期：2014-01-01 00:00:00

abstract：:To investigate the correlation between gender and the clinical presentation of papillary thyroid cancer and the long-term followup results, 435 patients who underwent total or near-total thyroidectomy were enrolled in this study. Among these papillary thyroid cancer patients, 12.2% showed lymph node metastases and a h...

journal_title：International journal of endocrinology

authors： Hsieh SH,Chen ST,Hsueh C,Chao TC,Lin JD

更新日期：2012-01-01 00:00:00

abstract：Objective:Aim of this study is to evaluate determinants of secondary normocalcemic hyperparathyroidism (SNHPT) persistence in patients who have undergone Roux-en-Y gastric bypass on vertical-banded gastroplasty. Methods:226 consecutive patients submitted to bariatric surgery were prospectively enrolled and divided in ...

journal_title：International journal of endocrinology

authors： Casella C,Molfino S,Mittempergher F,Cappelli C,Portolani N

更新日期：2018-03-06 00:00:00

abstract：:Sunlight-induced vitamin D, synthesis in the skin is the major source of vitamin D, but data on the relationship of sun-related behaviour with vitamin D and parathyroid hormone (PTH) levels are relatively sparse. We evaluated whether habitual sun exposure is associated with 25-hydroxyvitamin D (25[OH]D) and PTH levels...

journal_title：International journal of endocrinology

authors： Pilz S,Kienreich K,Stückler D,Meinitzer A,Tomaschitz A

更新日期：2012-01-01 00:00:00

abstract：:Islet cell transplantation is a promising beta cell replacement therapy for patients with brittle type 1 diabetes as well as refractory chronic pancreatitis. Despite the vast advancements made in this field, challenges still remain in achieving high frequency and long-term successful transplant outcomes. Here we revie...

journal_title：International journal of endocrinology

authors： Kanak MA,Takita M,Kunnathodi F,Lawrence MC,Levy MF,Naziruddin B

更新日期：2014-01-01 00:00:00

abstract：:Objectives. Vitamin D deficiency plays a role in insulin resistance and the pathogenesis of type 2 diabetes mellitus. Little information is available about the association between vitamin D status and insulin resistance in the Chinese population. Currently, vitamin D status is evaluated by the concentrations of serum ...

journal_title：International journal of endocrinology

authors： Zhang J,Ye J,Guo G,Lan Z,Li X,Pan Z,Rao X,Zheng Z,Luo F,Lin L,Lin Z,Xue Y

更新日期：2016-01-01 00:00:00

abstract：Introduction:Gut microbiota is involved in the progression of metabolic diseases such as obesity and type 2 diabetes. The ob/ob and db/db mice are extensively used as models in studies on the pathogenesis of these diseases. The goal of this study is to characterize the composition and structure of gut microbiota in the...

journal_title：International journal of endocrinology

authors： Yang M,Liu Y,Xie H,Wen Z,Zhang Y,Wu C,Huang L,Wu J,Xie C,Wang T,Peng W,Liu S,Chen L,Liu X

更新日期：2019-03-11 00:00:00

abstract：Objective:Neuroendocrine neoplasias (NENs) represent a rare and biologically heterogeneous group of malignancies. Treatment of NEN patients remains challenging due to lack of prospective evidence on the choice of ideal therapeutic sequence and therapeutic efficacy in specific individual scenarios. Methods:Clinical dat...

journal_title：International journal of endocrinology

authors： Mayer K,Kiry S,Yordanova A,Ahmadzadehfar H,Gaertner FC,Bundschuh RA,Essler M,Gonzalez-Carmona MA,Strassburg CP,Matthaei H,Lingohr P,Bisht S,Brossart P,Feldmann G

更新日期：2020-01-31 00:00:00

abstract：Aims:The present study assessed the therapeutic effect of exenatide and metformin as the initial therapy on overweight/obese patients with newly diagnosed type 2 diabetes (T2D). Methods:The prospective, nonrandomized, interventional study enrolled a total of 230 overweight or obese patients with newly diagnosed T2D wh...

journal_title：International journal of endocrinology

authors： Liu J,Hu Y,Xu Y,Jia Y,Miao L,Wang G

更新日期：2017-01-01 00:00:00

abstract：Background:Currently, energy obtained from hypercaloric diets has been part of the obesity and type 2 diabetes mellitus (T2DM) epidemics from childhood to old age. Treatment alternatives have been sought from plants, minerals, and trace elements with metabolic effects. Vanadyl sulfate (VS) has been investigated as a hy...

journal_title：International journal of endocrinology

authors： Ortega-Pacheco D,Jiménez-Pérez MM,Serafín-López J,Juárez-Rojas JG,Ruiz-García A,Pacheco-García U

更新日期：2018-12-25 00:00:00

abstract：:Anaplastic thyroid cancers (ATC) are among the most aggressive human neoplasms with a dire prognosis and a median survival time of few months from the diagnosis. The complete absence of effective therapies for ATC renders the identification of novel therapeutic approaches sorely needed. Chromosomal instability, a feat...

journal_title：International journal of endocrinology

authors： Baldini E,D'Armiento M,Ulisse S

更新日期：2014-01-01 00:00:00

abstract：:Plasma FGF-23 concentrations and its relationship with calcium-phosphate homeostasis were evaluated in 48 perimenopausal obese women and in 29 nonobese controls. Serum parathyroid hormone, 25-hydroxyvitamin D(3), CTX1, osteocalcin, total calcium, phosphorus, creatinine, and plasma intact FGF-23 concentrations were ass...

journal_title：International journal of endocrinology

authors： Holecki M,Chudek J,Więcek A,Titz-Bober M,Duława J

更新日期：2011-01-01 00:00:00

abstract：:Parathyroid glands contain the vitamin D receptor (VDR) and 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24A1), which catalyze the production and degradation of 1,25-dihydroxyvitamin D [1,25(OH)2D], respectively. Previous studies have shown that the serum level of intact parathyroid hormone (iPT...

journal_title：International journal of endocrinology

authors： Jiang Y,Liao L,Li J,Wang L,Xie Z

更新日期：2020-04-09 00:00:00

abstract：:Diabetes mellitus (DM) is one of the primary causes of premature death and disability worldwide. We performed a systematic review and meta-analysis of the published literature regarding the trends in prevalence, awareness, treatment, and control of diabetes mellitus in mainland China. PUBMED, EMBASE, Chinese Biomedica...

journal_title：International journal of endocrinology

authors： Li MZ,Su L,Liang BY,Tan JJ,Chen Q,Long JX,Xie JJ,Wu GL,Yan Y,Guo XJ,Gu L

更新日期：2013-01-01 00:00:00

abstract：:The chemosensitivity of anaplastic thyroid cancer (ATC) to some cytotoxic agents was investigated by the histoculture drug response assay (HDRA). Thirty specimens from 22 patients with ATC were obtained from surgically resected subjects. The drugs tested were paclitaxel (PTX), docetaxel (DOC), adriamycin (ADM), nedapl...

journal_title：International journal of endocrinology

authors： Uruno T,Masaki C,Akaishi J,Matsuzu K,Suzuki A,Ohkuwa K,Shibuya H,Kitagawa W,Nagahama M,Sugino K,Ito K

更新日期：2015-01-01 00:00:00

abstract：:A retrospective review of 626 patients with multifocal papillary thyroid carcinoma (PTC) including 147 patients (23.5%) with multifocal papillary thyroid microcarcinoma (PTMC) from a total of 2,536 patients with PTC who visited the Chang Gung Medical Center in Linkou, Taiwan, was performed. A comparison of the clinica...

journal_title：International journal of endocrinology

authors： Ng SC,Kuo SF,Chen ST,Hsueh C,Huang BY,Lin JD

更新日期：2017-01-01 00:00:00

abstract：:Objective. Patients with more than two spontaneous pregnancy losses are diagnosed with recurrent pregnancy loss. The aim of this study was to evaluate the IR (insulin resistance) in patients with idiopathic recurrent pregnancy loss. Material and Method. A single center, case control study was performed on one hundred ...

journal_title：International journal of endocrinology

authors： Ispasoiu CA,Chicea R,Stamatian FV,Ispasoiu F

更新日期：2013-01-01 00:00:00

abstract：:The study aimed at assessing the potential use of lower total and HMW adiponectin levels for predicting cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). Concentrations of total adiponectin or high molecular weight (HMW) adiponectin decrease in association with the development of metabolic dysfunct...

journal_title：International journal of endocrinology

authors： Horáková D,Azeem K,Benešová R,Pastucha D,Horák V,Dumbrovská L,Martínek A,Novotný D,Švagera Z,Hobzová M,Galuszková D,Janout V,Doněvská S,Vrbková J,Kollárová H

更新日期：2015-01-01 00:00:00

abstract：Introduction:Cushing's syndrome (CS) is a clinical condition characterized by excessive cortisol production, associated with metabolic complications, such as diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, and cardiovascular diseases. Nowadays, the occurrence of autoimmune diseases in CS have not bee...

journal_title：International journal of endocrinology

authors： Petramala L,Olmati F,Conforti MG,Concistré A,Bisogni V,Alfieri N,Iannucci G,de Toma G,Letizia C

更新日期：2018-12-18 00:00:00

abstract：:Type 2 diabetes is characterized by frequent ectopic fat accumulation in several tissues and organs. In particular, a number of studies showed that these subjects frequently have hepatic fat accumulation, which may play a role in the metabolic abnormalities typical of diabetes and has been also linked to increased ris...

journal_title：International journal of endocrinology

authors： Bacchi E,Moghetti P

更新日期：2013-01-01 00:00:00

abstract：:Thyroid function and microalbuminuria are both associated with vascular disease and endothelial damage. However, whether thyroid function is associated with microalbuminuria is not well established. The objective was to explore the relationship between thyroid hormones and microalbuminuria in Chinese population. A com...

journal_title：International journal of endocrinology

authors： Zhou Y,Ye L,Wang T,Hong J,Bi Y,Zhang J,Xu B,Sun J,Huang X,Xu M

更新日期：2014-01-01 00:00:00

abstract：:Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by differences in fasting non-esterified fatty acid (NEFA) levels and/or NEFA suppression after oral ...

journal_title：International journal of endocrinology

authors： Finucane FM,Sharp SJ,Hatunic M,Sleigh A,De Lucia Rolfe E,Sayer AA,Cooper C,Griffin SJ,Savage DB,Wareham NJ

更新日期：2013-01-01 00:00:00

abstract：Purpose:Hyperoside, a flavonoid isolated from conventional medicinal herbs, has been demonstrated to exert a significant protective effect in diabetic nephropathy. This study aimed to determine the underlying mechanisms, by which hyperoside inhibits high glucose-(HG-) induced proliferation in mouse renal mesangial cell...

journal_title：International journal of endocrinology

authors： Zhang L,Dai Q,Hu L,Yu H,Qiu J,Zhou J,Long M,Zhou S,Zhang K

更新日期：2020-07-21 00:00:00

abstract：Objective:Selenium, as an antioxidant, has been implicated in the development of autoimmune thyroiditis (AIT). Many studies showed selenium supplementation could decrease thyroid autoantibodies in patients with AIT. However, the underlying mechanisms have not been well determined. Therefore, we performed a clinical stu...

journal_title：International journal of endocrinology

authors： Tian X,Li N,Su R,Dai C,Zhang R

更新日期：2020-06-30 00:00:00

abstract：:The aim of this review was to summarize current knowledge on the correlation between depressive symptoms with a syndrome called partial androgen deficiency of the aging male (PADAM) and on the potential benefits of testosterone (T) treatment on mood. Despite, the causative nature of the relationship between low T leve...

journal_title：International journal of endocrinology

authors： Amore M,Innamorati M,Costi S,Sher L,Girardi P,Pompili M

更新日期：2012-01-01 00:00:00

abstract：:Stevia rebaudiana (Bert.) Bertoni besides being a source of noncaloric sweeteners is also an important source of bioactive molecules. Many plant extracts, mostly obtained with ethyl acetate solvent, are rich in polyphenol compounds that present insulinotropic effects. To investigate whether the nonsweetener fraction, ...

journal_title：International journal of endocrinology

authors： Piovan S,Pavanello A,Peixoto GML,Matiusso CCI,de Moraes AMP,Martins IP,Malta A,Palma-Rigo K,da Silva Franco CC,Milani PG,Dacome AS,da Costa SC,de Freitas Mathias PC,Mareze-Costa CE

更新日期：2018-04-29 00:00:00

abstract：:The circadian system is a supraphysiological system that modulates different biological functions such as metabolism, sleep-wake, cellular proliferation, and body temperature. Different chronodisruptors have been identified, such as shift work, feeding time, long days, and stress. The environmental changes and our mod...

journal_title：International journal of endocrinology

authors： Valenzuela FJ,Vera J,Venegas C,Muñoz S,Oyarce S,Muñoz K,Lagunas C

更新日期：2016-01-01 00:00:00

abstract：:Background. The purpose of the present study was to assess the feasibility of using miR-126 in the urine as a biomarker for diabetic nephropathy. Methods. miRNAs were extracted from the urine samples of T2DM patients with diabetic nephropathy (DN; n = 92), T2DM without DN (n = 86), and 85 healthy volunteers using quan...

journal_title：International journal of endocrinology

authors： Liu Y,Gao G,Yang C,Zhou K,Shen B,Liang H,Jiang X

更新日期：2014-01-01 00:00:00