Comparison of Exenatide and Metformin Monotherapy in Overweight/Obese Patients with Newly Diagnosed Type 2 Diabetes.

abstract：Background:The aim was to investigate the amounts of saliva and serum asprosin in order to determine whether it is related to obesity and whether salivary glands synthesize asprosin or not. Methods:A total of 116 underweight, normal weight, overweight, and obese (class I, class II, and class III) volunteers participat...

journal_title：International journal of endocrinology

authors： Ugur K,Aydin S

更新日期：2019-03-27 00:00:00

abstract：:Objective. In pediatric central diabetes insipidus (CDI), etiology diagnosis and pituitary function monitoring are usually delayed. This study aimed to illustrate the importance of regular follow-up and pituitary function monitoring in pediatric CDI. Methods. The clinical, hormonal, and neuroradiological characteristi...

journal_title：International journal of endocrinology

authors： Liu W,Wang L,Liu M,Li G

更新日期：2016-01-01 00:00:00

abstract：:Diabetes is a lifelong course disease, so insulin treatment has to be effective and safe, and patients should be satisfied with it. We aimed to compare efficacy, safety, and quality of treatment satisfaction of human and premixed analogue insulin among 3264 patients (53.58% women) with type 2 diabetes mellitus (T2DM) ...

journal_title：International journal of endocrinology

authors： Nabrdalik K,Kwiendacz H,Sawczyn T,Tomasik A,Kukla M,Masierek M,Gumprecht J

更新日期：2018-03-05 00:00:00

abstract：:Background. Papillary thyroid cancer (PTC) exhibits a higher incidence in women. Due to various ages at menarche and menopause, estrogen levels vary, which may account for the differences in the occurrence, development, and prognosis of female patients with PTC. Objective. The aim of this study was to investigate the ...

journal_title：International journal of endocrinology

authors： Zhu X,Yu B,Huang YQ,Zhou JN,Ge MH

更新日期：2017-01-01 00:00:00

abstract：:Objective. To explore whether GC (group-specific component) rs17467825, rs4588, and rs7041 polymorphisms are associated with generalized aggressive periodontitis. Methods. This case-control study recruited 372 patients with generalized aggressive periodontitis (group AgP) and 133 periodontal healthy subjects (group HP...

journal_title：International journal of endocrinology

authors： Song W,Wang X,Tian Y,Zhang X,Lu R,Meng H

更新日期：2016-01-01 00:00:00

abstract：:The increased prevalence of obesity represents, currently, one of the major public health issues, due to its consequences on physical and psychological health status as well as on the psychosocial functioning. As defined by the World Health Organization, sexual health is "a state of physical, emotional, mental, and so...

journal_title：International journal of endocrinology

authors： Poggiogalle E,Di Lazzaro L,Pinto A,Migliaccio S,Lenzi A,Donini LM

更新日期：2014-01-01 00:00:00

abstract：Objective:To identify the clinicopathological features correlated to lymph node metastasis (LNM) in patients with papillary thyroid microcarcinoma (PTMC). Methods:Clinical data of 785 PTMC patients who underwent surgical treatment at the Lishui Municipal Central Hospital from September 2008 to December 2017 were retro...

journal_title：International journal of endocrinology

authors： Cheng F,Chen Y,Zhu L,Zhou B,Xu Y,Chen Y,Wen L,Chen S

更新日期：2019-01-15 00:00:00

abstract：Objective:We sought to evaluate the association between femoral neck (FN) and lumbar spine (LS) bone mineral densities (BMDs) with severity of chronic kidney disease (CKD) and prevalence of osteopenia or osteoporosis (OP) among the CKD group. Methods:Cross-sectional data from 11050 participants aged ≥20 years from the...

journal_title：International journal of endocrinology

authors： Huang JF,Zheng XQ,Sun XL,Zhou X,Liu J,Li YM,Wang XY,Zhang XL,Wu AM

更新日期：2020-10-26 00:00:00

abstract：:Leptin and adiponectin are differentially expressed adipokines in obesity and cardiovascular diseases. Leptin levels are directly associated with adipose tissue mass, while adiponectin levels are downregulated in obesity. Although significantly produced by adipocytes, leptin is also produced by vascular smooth muscle ...

journal_title：International journal of endocrinology

authors： Ghantous CM,Azrak Z,Hanache S,Abou-Kheir W,Zeidan A

更新日期：2015-01-01 00:00:00

abstract：:To isolate pancreatic progenitor cells with the surface markers of hematopoietic stem cells, the expression of stem cell antigen (Sca-1) and c-Kit and the coexpression of them with pancreatic duodenal homeobox-1 (PDX-1), neurogenin 3 (Ngn3), and insulin were examined in murine embryonic pancreas. Then different pancre...

journal_title：International journal of endocrinology

authors： Ma F,Chen F,Chi Y,Yang S,Lu S,Han Z

更新日期：2012-01-01 00:00:00

abstract：:Background. Abdominal obesity and its relative distribution are known to differ in association with metabolic characteristics and cardiorespiratory fitness. This study aimed to determine an association between fitness level and abdominal adiposity in overweight and obese adults. Methods. 228 overweight and obese indiv...

journal_title：International journal of endocrinology

authors： Kim S,Kim JY,Lee DC,Lee HS,Lee JW,Jeon JY

更新日期：2014-01-01 00:00:00

abstract：:Background. Hyperinsulinaemic Hypoglycaemia (HH) is the most common cause of severe and persistent hypoglycemia in the neonatal period. It has been shown that the neonates with HH fail to generate adequate serum cortisol counterregulatory response to symptomatic hypoglycemia. However the role played by growth hormone ...

journal_title：International journal of endocrinology

authors： Senniappan S,Hussain K

更新日期：2013-01-01 00:00:00

abstract：:Background. Management of thyroid nodules with benign aspirates following atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) is not well established. We reviewed the risk of malignancy and the role of ultrasound (US) features among thyroid nodules with benign results followin...

journal_title：International journal of endocrinology

authors： Kim GR,Yoon JH,Kim EK,Moon HJ,Kwak JY

更新日期：2014-01-01 00:00:00

abstract：:To investigate effects of long-term testosterone (T) therapy in obese men with T deficiency (TD) and type 2 diabetes mellitus (T2DM), data were collected from two observational, prospective, and cumulative registry studies of 561 men with TD receiving T therapy for up to 6 years. A subgroup of obese hypogonadal men wi...

journal_title：International journal of endocrinology

authors： Haider A,Yassin A,Doros G,Saad F

更新日期：2014-01-01 00:00:00

abstract：:Propylthiouracil- (PTU-) induced hepatotoxicity is rare but potentially lethal with a spectrum of liver injury ranging from asymptomatic elevation of transaminases to fulminant hepatic failure and death. We describe two cases of acute hepatic failure due to PTU that required liver transplantation. Differences in the c...

journal_title：International journal of endocrinology

authors： Carrion AF,Czul F,Arosemena LR,Selvaggi G,Garcia MT,Tekin A,Tzakis AG,Martin P,Ghanta RK

更新日期：2010-01-01 00:00:00

abstract：:Background. Oxidative stress induced by reactive oxygen and nitrogen species is critically involved in the impairment of β -cell function during the development of diabetes. Methods. HIT-T15 cells were cultured in 5% CO2 and then preincubated with Gelam honey extracts (20, 40, 60, and 80 µg/mL) as well as quercetin (2...

journal_title：International journal of endocrinology

authors： Batumalaie K,Zaman Safi S,Mohd Yusof K,Shah Ismail I,Devi Sekaran S,Qvist R

更新日期：2013-01-01 00:00:00

abstract：:Insulin resistance increases the risk for cardiovascular disease (CVD) even in the absence of classic risk factors, such as hyperglycemia, hypertension, dyslipidemia, and obesity. Low-grade chronic inflammatory state is associated both with insulin resistance and atherosclerosis. An increased circulating level of proi...

journal_title：International journal of endocrinology

authors： Nikołajuk A,Matulewicz N,Stefanowicz M,Karczewska-Kupczewska M

更新日期：2018-09-13 00:00:00

abstract：:Anaplastic thyroid cancers (ATC) are among the most aggressive human neoplasms with a dire prognosis and a median survival time of few months from the diagnosis. The complete absence of effective therapies for ATC renders the identification of novel therapeutic approaches sorely needed. Chromosomal instability, a feat...

journal_title：International journal of endocrinology

authors： Baldini E,D'Armiento M,Ulisse S

更新日期：2014-01-01 00:00:00

abstract：:Prostate cancer (PCa) is the most common malignancy in elderly men. The progressive ageing of the world male population will further increase the need for tailored assessment and treatment of PCa patients. The determinant role of androgens and sexual hormones for PCa growth and progression has been established. Howeve...

journal_title：International journal of endocrinology

authors： Gacci M,Baldi E,Tamburrino L,Detti B,Livi L,De Nunzio C,Tubaro A,Gravas S,Carini M,Serni S

更新日期：2014-01-01 00:00:00

abstract：Background:Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone-binding globulin (SHBG) and albumin. Only 1-2% of nonprotein-bound te...

journal_title：International journal of endocrinology

authors： Antonio L,Pauwels S,Laurent MR,Vanschoubroeck D,Jans I,Billen J,Claessens F,Decallonne B,De Neubourg D,Vermeersch P,Vanderschueren D

更新日期：2018-09-10 00:00:00

abstract：Objective:Atypical parathyroid adenoma is a rare neoplasm, showing atypical histological features intermediate between classic benign adenoma and the rarest parathyroid carcinoma, whose the clinical behaviour and outcome is not yet understood or predictable. Up to date only two cases of atypical adenoma were found asso...

journal_title：International journal of endocrinology

authors： Cinque L,Pugliese F,Clemente C,Castellana S,Leone MP,de Martino D,Balsamo T,Battista C,Biagini T,Graziano P,Castori M,Scillitani A,Guarnieri V

更新日期：2020-04-27 00:00:00

abstract：:In the last 20 years, a pituitary-hypothalamus tissue culture system with intact neural and portal connections has been developed in our lab and used to understand the feedback mechanisms that regulate the secretions of adenohypophyseal hormones and fertility of male rats. In the last decade, several in vivo rat model...

journal_title：International journal of endocrinology

authors： Gill-Sharma MK

更新日期：2009-01-01 00:00:00

abstract：:Background. Nonclassic congenital adrenal hyperplasia (NCAH), caused by mutations in the gene encoding 21-hydroxylase, is a common autosomal recessive disorder. In the present work, our aim was to determine the prevalence of NCAH presenting as premature pubarche (PP), hirsutism, or polycystic ovarian syndrome (PCOS) a...

journal_title：International journal of endocrinology

authors： Binay C,Simsek E,Cilingir O,Yuksel Z,Kutlay O,Artan S

更新日期：2014-01-01 00:00:00

abstract：:Glucose is the major source of energy for the human brain which in turn uses ketone bodies as a supplement for energy deficit in glucose cell deficiency conditions. Pregnancy complicated by gestational diabetes is a condition associated with significantly increased risk of ketonemia development. The data available pro...

journal_title：International journal of endocrinology

authors： Bronisz A,Ozorowski M,Hagner-Derengowska M

更新日期：2018-06-04 00:00:00

abstract：Objective:Cystic parathyroid adenoma is a rare cause of primary hyperparathyroidism, but its preoperative diagnosis and management remain inconclusive. Method:We retrospectively identified patients with cystic parathyroid adenomas who underwent surgery at Peking Union Medical College Hospital. Results:Patients with c...

journal_title：International journal of endocrinology

authors： Hu Y,Cui M,Xia Y,Su Z,Zhang X,Liao Q,Jiang Y,Zhao Y

更新日期：2018-07-15 00:00:00

abstract：:The aim of this review was to summarize current knowledge on the correlation between depressive symptoms with a syndrome called partial androgen deficiency of the aging male (PADAM) and on the potential benefits of testosterone (T) treatment on mood. Despite, the causative nature of the relationship between low T leve...

journal_title：International journal of endocrinology

authors： Amore M,Innamorati M,Costi S,Sher L,Girardi P,Pompili M

更新日期：2012-01-01 00:00:00

abstract：:Aim. To compare two creatinine-based estimated glomerular filtration rate (eGFR) equations, the chronic kidney disease epidemiology collaboration (CKD-EPI) and the modification of diet in renal disease (MDRD), for predicting the risk of CKD progression in type 2 diabetic patients with nephropathy. Methods. A total of ...

journal_title：International journal of endocrinology

authors： Lee EY,Lee YM,Choi KH,Lee HC,Lee BW,Kim BS

更新日期：2013-01-01 00:00:00

abstract：:The goal of this study was to determine the prevalence and associated risk factors of impaired glucose regulation (IGR) in the population of Tongzhou, China, and to provide scientific basis for preventive interventions. In the study, the overall age-standardized prevalence of IGR (16.0%) in Tongzhou residents was high...

journal_title：International journal of endocrinology

authors： Zhao D,Wu N,Yang J,Liu S,Zhang N,Wang X,Zhang H

更新日期：2015-01-01 00:00:00

abstract：:The chemosensitivity of anaplastic thyroid cancer (ATC) to some cytotoxic agents was investigated by the histoculture drug response assay (HDRA). Thirty specimens from 22 patients with ATC were obtained from surgically resected subjects. The drugs tested were paclitaxel (PTX), docetaxel (DOC), adriamycin (ADM), nedapl...

journal_title：International journal of endocrinology

authors： Uruno T,Masaki C,Akaishi J,Matsuzu K,Suzuki A,Ohkuwa K,Shibuya H,Kitagawa W,Nagahama M,Sugino K,Ito K

更新日期：2015-01-01 00:00:00

abstract：Background:Little information is available on the association between parents' metabolic syndrome (MetS) and adolescent offspring's obesity in Korea. The aim of our study is to determine the association between parent's metabolic syndrome and offspring's obesity. Methods:The study data were obtained from the Korean Na...

journal_title：International journal of endocrinology

authors： Lee NY,Han K,Lee Y,Kim S,Lee S,Choi Y,Ahn MB,Kim SH,Cho WK,Cho KS,Jung MH,Park YG,Suh BK

更新日期：2020-10-30 00:00:00