Abstract:
:The goal of this study was to determine the prevalence and associated risk factors of impaired glucose regulation (IGR) in the population of Tongzhou, China, and to provide scientific basis for preventive interventions. In the study, the overall age-standardized prevalence of IGR (16.0%) in Tongzhou residents was higher than that in the national population (15.0%). There was no significant geographic difference in prevalence of IGR between urban and rural males. Older age, elevated blood pressure, high serum lipids, overweight, and central obesity were significantly associated with increased risk of IGR.
journal_name
Int J Endocrinoljournal_title
International journal of endocrinologyauthors
Zhao D,Wu N,Yang J,Liu S,Zhang N,Wang X,Zhang Hdoi
10.1155/2015/731583subject
Has Abstractpub_date
2015-01-01 00:00:00pages
731583eissn
1687-8337issn
1687-8345journal_volume
2015pub_type
杂志文章abstract::In the last decade, miRNAs have received substantial attention as potential players of diabetes microvascular complications, affecting the kidney, the retina, and the peripheral neurons. Compelling evidence indicates that abnormally expressed miRNAs have pivotal roles in key pathogenic processes of microvascular compl...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2018/6890501
更新日期:2018-03-07 00:00:00
abstract::Anaplastic thyroid cancers (ATC) are among the most aggressive human neoplasms with a dire prognosis and a median survival time of few months from the diagnosis. The complete absence of effective therapies for ATC renders the identification of novel therapeutic approaches sorely needed. Chromosomal instability, a feat...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2014/816430
更新日期:2014-01-01 00:00:00
abstract::Objective. To analyze changes in vital signs (heart rate (HR), systolic (SBP), and diastolic blood pressure (DBP)) during and after intravenous methylprednisolone (IVMP) and any other adverse effects. Methods. Retrospective review of charts of patients who received IVMP as treatment regime for thyroid eye disease. All...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2015/457123
更新日期:2015-01-01 00:00:00
abstract::Polycystic ovary syndrome (PCOS) is the most common endocrine disorder amongst women of reproductive age. Although PCOS is diagnosed exclusively based on reproductive criteria, it is also a metabolic disorder. Insulin resistance, impaired glucose tolerance, type 2 diabetes mellitus, obesity, and dyslipidemia are more ...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2015/786362
更新日期:2015-01-01 00:00:00
abstract:Objective:Cystic parathyroid adenoma is a rare cause of primary hyperparathyroidism, but its preoperative diagnosis and management remain inconclusive. Method:We retrospectively identified patients with cystic parathyroid adenomas who underwent surgery at Peking Union Medical College Hospital. Results:Patients with c...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2018/3745239
更新日期:2018-07-15 00:00:00
abstract::Vascular calcification and bone fragility are common and interrelated health problems that affect chronic kidney disease (CKD) patients. Bone fragility, which leads to higher risk of fracture and mortality, arises from the abnormal bone remodeling and mineralization that are seen in chronic kidney disease. Recently, s...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2018/5893514
更新日期:2018-04-02 00:00:00
abstract::Preeclampsia is a serious medical problem affecting the mother and her child and influences their health not only during the pregnancy, but also many years after. Although preeclampsia is a subject of many research projects, the etiology of the condition remains unclear. One of the hypotheses related to the etiology o...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2016/5279462
更新日期:2016-01-01 00:00:00
abstract:Objective:We sought to evaluate the association between femoral neck (FN) and lumbar spine (LS) bone mineral densities (BMDs) with severity of chronic kidney disease (CKD) and prevalence of osteopenia or osteoporosis (OP) among the CKD group. Methods:Cross-sectional data from 11050 participants aged ≥20 years from the...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2020/8852690
更新日期:2020-10-26 00:00:00
abstract::Aims. To evaluate the predictive power of pretransplant HbA1c for new-onset diabetes after transplantation (NODAT) in kidney transplant candidates, who had several predispositions for fluctuated HbA1c levels. Methods. We performed a retrospective study of 119 patients without diabetes who received kidney transplantati...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2014/436725
更新日期:2014-01-01 00:00:00
abstract::Aim. Our aim was (1) to determine the frequency of insulin resistance (IR) in patients with Duchenne/Becker muscular dystrophy (DMD/BMD), (2) to identify deleted exons of DMD gene associated with obesity and IR, and (3) to explore some likely molecular mechanisms leading to IR. Materials and Methods. In 66 patients wi...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2015/867273
更新日期:2015-01-01 00:00:00
abstract::The aim of this study is to evaluate carotid atherosclerosis in patients of type 2 diabetes mellitus with microalbuminuria (MA) by high-frequency ultrasonography. Two hundred and fifty patients of type 2 diabetes mellitus were divided into two groups according to urinary albumin excretion rate (UAER): normoalbuminuria...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2013/819584
更新日期:2013-01-01 00:00:00
abstract::Thyroid function and microalbuminuria are both associated with vascular disease and endothelial damage. However, whether thyroid function is associated with microalbuminuria is not well established. The objective was to explore the relationship between thyroid hormones and microalbuminuria in Chinese population. A com...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2014/959781
更新日期:2014-01-01 00:00:00
abstract::Propylthiouracil- (PTU-) induced hepatotoxicity is rare but potentially lethal with a spectrum of liver injury ranging from asymptomatic elevation of transaminases to fulminant hepatic failure and death. We describe two cases of acute hepatic failure due to PTU that required liver transplantation. Differences in the c...
journal_title:International journal of endocrinology
pub_type:
doi:10.1155/2010/910636
更新日期:2010-01-01 00:00:00
abstract::Ghrelin is a relatively novel multifaceted hormone that has been found to exert a plethora of physiological effects. In this review, we found/confirmed that ghrelin has effect on all body systems. It induces appetite; promotes the use of carbohydrates as a source of fuel while sparing fat; inhibits lipid oxidation and...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2020/1385138
更新日期:2020-05-25 00:00:00
abstract::Background. Pediatric CAH patients have an increased risk of cardiovascular disease, and it remains unknown if genetic predisposition is a contributing factor. Glucocorticoid receptor gene (NR3C1) polymorphisms are associated with an adverse metabolic profile. Our aim was to analyze the association between the NR3C1 p...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2014/594710
更新日期:2014-01-01 00:00:00
abstract::Background. Management of thyroid nodules with benign aspirates following atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) is not well established. We reviewed the risk of malignancy and the role of ultrasound (US) features among thyroid nodules with benign results followin...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2014/354612
更新日期:2014-01-01 00:00:00
abstract:Objective:Aim of this study is to evaluate determinants of secondary normocalcemic hyperparathyroidism (SNHPT) persistence in patients who have undergone Roux-en-Y gastric bypass on vertical-banded gastroplasty. Methods:226 consecutive patients submitted to bariatric surgery were prospectively enrolled and divided in ...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2018/5010287
更新日期:2018-03-06 00:00:00
abstract::Background. Nonclassic congenital adrenal hyperplasia (NCAH), caused by mutations in the gene encoding 21-hydroxylase, is a common autosomal recessive disorder. In the present work, our aim was to determine the prevalence of NCAH presenting as premature pubarche (PP), hirsutism, or polycystic ovarian syndrome (PCOS) a...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2014/768506
更新日期:2014-01-01 00:00:00
abstract::The study aimed at assessing the potential use of lower total and HMW adiponectin levels for predicting cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). Concentrations of total adiponectin or high molecular weight (HMW) adiponectin decrease in association with the development of metabolic dysfunct...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2015/545068
更新日期:2015-01-01 00:00:00
abstract::Aims. To seek high risk population for diabetes and to improve their health care by investigating the characteristics and outcome of hospitalization in hospitals with predominant Arab patients in Northern Israel. Methods. Retrospective analysis of the prevalence of diabetes and the outcome of diabetic in comparison to...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2013/371608
更新日期:2013-01-01 00:00:00
abstract::The liver is one of the most essential organs involved in the regulation of energy homeostasis. Hepatic steatosis, a major manifestation of metabolic syndrome, is associated with imbalance between lipid formation and breakdown, glucose production and catabolism, and cholesterol synthesis and secretion. Epidemiological...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2015/294278
更新日期:2015-01-01 00:00:00
abstract::Obesity is a growing problem in modern society and medicine. It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myocarditis, and hypertension. Obesity is often associated with latent i...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2017/5076732
更新日期:2017-01-01 00:00:00
abstract::Purpose. To evaluate the associations between metformin, insulin, statins, and levothyroxine and breast cancer characteristics and outcome. Methods. Retrospective chart review of patients treated in our institute for early estrogen receptor (ER) positive, human epidermal growth factor receptor 2 negative breast cancer...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2016/4658469
更新日期:2016-01-01 00:00:00
abstract::Background. Hyperinsulinaemic Hypoglycaemia (HH) is the most common cause of severe and persistent hypoglycemia in the neonatal period. It has been shown that the neonates with HH fail to generate adequate serum cortisol counterregulatory response to symptomatic hypoglycemia. However the role played by growth hormone ...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2013/638257
更新日期:2013-01-01 00:00:00
abstract::Islet cell transplantation is a promising beta cell replacement therapy for patients with brittle type 1 diabetes as well as refractory chronic pancreatitis. Despite the vast advancements made in this field, challenges still remain in achieving high frequency and long-term successful transplant outcomes. Here we revie...
journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
doi:10.1155/2014/451035
更新日期:2014-01-01 00:00:00
abstract:Background:Insulin promotes glucose consumption as the main cardiac energy source, while increasing myocardial efficiency. The short-term effects of insulin on cardiac function and its potential curative role in an acute diabetological cardiology setting remain unknown. Our study evaluated the role of acute insulin adm...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2020/8134548
更新日期:2020-03-17 00:00:00
abstract:Introduction:Cushing's syndrome (CS) is a clinical condition characterized by excessive cortisol production, associated with metabolic complications, such as diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, and cardiovascular diseases. Nowadays, the occurrence of autoimmune diseases in CS have not bee...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2018/1464967
更新日期:2018-12-18 00:00:00
abstract::Stevia rebaudiana (Bert.) Bertoni besides being a source of noncaloric sweeteners is also an important source of bioactive molecules. Many plant extracts, mostly obtained with ethyl acetate solvent, are rich in polyphenol compounds that present insulinotropic effects. To investigate whether the nonsweetener fraction, ...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2018/3189879
更新日期:2018-04-29 00:00:00
abstract::In the present study we evaluated in vivo and in vitro effects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin, β -catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents, bank voles. We found that in bank vole testes expression and dist...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2013/134589
更新日期:2013-01-01 00:00:00
abstract::In obese diabetic subjects, a correct life style, including diet and physical activity, is part of a correct intervention protocol. Thus, the aim of this study was to evaluate the effects of aerobic training intervention, based on heart rate at aerobic gas exchange threshold (AerTge), on clinical and physiological par...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2015/695297
更新日期:2015-01-01 00:00:00