Latent Inflammation and Insulin Resistance in Adipose Tissue.

abstract：:The study explored the utility of four-point preprandial glucose self-monitoring to calculate several indices of glycemic control and variability in a study adding the DPP-4 inhibitor vildagliptin to ongoing insulin therapy. This analysis utilized data from a double-blind, randomized, placebo-controlled crossover stud...

journal_title：International journal of endocrinology

authors： Tura A,Farngren J,Schweizer A,Foley JE,Pacini G,Ahrén B

更新日期：2015-01-01 00:00:00

abstract：:Plasma FGF-23 concentrations and its relationship with calcium-phosphate homeostasis were evaluated in 48 perimenopausal obese women and in 29 nonobese controls. Serum parathyroid hormone, 25-hydroxyvitamin D(3), CTX1, osteocalcin, total calcium, phosphorus, creatinine, and plasma intact FGF-23 concentrations were ass...

journal_title：International journal of endocrinology

authors： Holecki M,Chudek J,Więcek A,Titz-Bober M,Duława J

更新日期：2011-01-01 00:00:00

abstract：:Objectives. Statin drugs act as inhibitors of the 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase enzyme early in the mevalonate pathway, thereby reducing the endogenous cholesterol synthesis. In recent studies, it has been suggested from epidemiological data that statins also may improve vitamin D status, as...

journal_title：International journal of endocrinology

authors： Rejnmark L,Vestergaard P,Heickendorff L,Mosekilde L

更新日期：2010-01-01 00:00:00

abstract：:In the last 20 years, a pituitary-hypothalamus tissue culture system with intact neural and portal connections has been developed in our lab and used to understand the feedback mechanisms that regulate the secretions of adenohypophyseal hormones and fertility of male rats. In the last decade, several in vivo rat model...

journal_title：International journal of endocrinology

authors： Gill-Sharma MK

更新日期：2009-01-01 00:00:00

abstract：:Background. Nonclassic congenital adrenal hyperplasia (NCAH), caused by mutations in the gene encoding 21-hydroxylase, is a common autosomal recessive disorder. In the present work, our aim was to determine the prevalence of NCAH presenting as premature pubarche (PP), hirsutism, or polycystic ovarian syndrome (PCOS) a...

journal_title：International journal of endocrinology

authors： Binay C,Simsek E,Cilingir O,Yuksel Z,Kutlay O,Artan S

更新日期：2014-01-01 00:00:00

abstract：:Objectives. The roles of PI3K/AKT/mTOR and MAPK/ERK pathways involved in the pathogenesis of pheochromocytoma and paraganglioma (PPGL) were demonstrated mostly by in vitro studies with rat or mouse cells and were mainly studied at transcriptional level. This study aimed to investigate the effect of these pathways on t...

journal_title：International journal of endocrinology

authors： Du J,Tong A,Wang F,Cui Y,Li C,Zhang Y,Yan Z

更新日期：2016-01-01 00:00:00

abstract：Objective:Neuroendocrine neoplasias (NENs) represent a rare and biologically heterogeneous group of malignancies. Treatment of NEN patients remains challenging due to lack of prospective evidence on the choice of ideal therapeutic sequence and therapeutic efficacy in specific individual scenarios. Methods:Clinical dat...

journal_title：International journal of endocrinology

authors： Mayer K,Kiry S,Yordanova A,Ahmadzadehfar H,Gaertner FC,Bundschuh RA,Essler M,Gonzalez-Carmona MA,Strassburg CP,Matthaei H,Lingohr P,Bisht S,Brossart P,Feldmann G

更新日期：2020-01-31 00:00:00

abstract：:Purpose. To evaluate whether inferior rectus muscle (IRM) thickness, the degree of adipose change in the IRM, smoking status, and the previous history of orbital radiotherapy can predict the dose-effect relationship regarding unilateral IRM recession in thyroid eye disease (TED). Methods. Twenty-five patients were ret...

journal_title：International journal of endocrinology

authors： Takahashi Y,Kakizaki H

更新日期：2015-01-01 00:00:00

abstract：:Ghrelin is a relatively novel multifaceted hormone that has been found to exert a plethora of physiological effects. In this review, we found/confirmed that ghrelin has effect on all body systems. It induces appetite; promotes the use of carbohydrates as a source of fuel while sparing fat; inhibits lipid oxidation and...

journal_title：International journal of endocrinology

authors： Akalu Y,Molla MD,Dessie G,Ayelign B

更新日期：2020-05-25 00:00:00

abstract：:Present therapies to minify hyperglycaemia and insulin resistance mainly target ATP-sensitive K(+) channels (K(ATP)) of pancreatic cells and PPAR-γ to enhance the insulin secretion and potential for GLUT expression, respectively. These current approaches are frequently associated with the various side effects such as ...

journal_title：International journal of endocrinology

authors： Ahmed D,Sharma M

更新日期：2011-01-01 00:00:00

abstract：:Type 2 diabetes mellitus (T2D) is a disorder of glucose metabolism. It is a complex process involving the regulation of insulin secretion, insulin sensitivity, gluconeogenesis, and glucose uptake at the cellular level. Diabetic peripheral neuropathy (DPN) is one of the debilitating complications that is present in app...

journal_title：International journal of endocrinology

authors： Prabodha LBL,Sirisena ND,Dissanayake VHW

更新日期：2018-03-15 00:00:00

abstract：:To investigate the correlation between gender and the clinical presentation of papillary thyroid cancer and the long-term followup results, 435 patients who underwent total or near-total thyroidectomy were enrolled in this study. Among these papillary thyroid cancer patients, 12.2% showed lymph node metastases and a h...

journal_title：International journal of endocrinology

authors： Hsieh SH,Chen ST,Hsueh C,Chao TC,Lin JD

更新日期：2012-01-01 00:00:00

abstract：:Estroprogestins (EPs) are combinations of estrogen and progestin with several actions on women's health. The different pharmacological composition of EPs is responsible for different clinical effects. One of the most used low-dose EP associations is ethinylestradiol 20 mcg plus levonorgestrel 100 mcg in monophasic reg...

journal_title：International journal of endocrinology

authors： Lello S,Cavani A

更新日期：2014-01-01 00:00:00

abstract：:Anaplastic thyroid cancers (ATC) are among the most aggressive human neoplasms with a dire prognosis and a median survival time of few months from the diagnosis. The complete absence of effective therapies for ATC renders the identification of novel therapeutic approaches sorely needed. Chromosomal instability, a feat...

journal_title：International journal of endocrinology

authors： Baldini E,D'Armiento M,Ulisse S

更新日期：2014-01-01 00:00:00

abstract：:Aims. There are two phases of insulin secretion, the first (FPIS) and second phase (SPIS). In this study, we built equations to predict FPIS with metabolic syndrome (MetS) components and fasting plasma insulin (FPI). Methods. Totally, 186 participants were enrolled. 75% of participants were randomly selected as the st...

journal_title：International journal of endocrinology

authors： Lin JD,Hsu CH,Liang YJ,Lian WC,Hsieh CH,Wu CZ,Pei D,Chen YL

更新日期：2015-01-01 00:00:00

abstract：:In obese diabetic subjects, a correct life style, including diet and physical activity, is part of a correct intervention protocol. Thus, the aim of this study was to evaluate the effects of aerobic training intervention, based on heart rate at aerobic gas exchange threshold (AerTge), on clinical and physiological par...

journal_title：International journal of endocrinology

authors： Emerenziani GP,Gallotta MC,Meucci M,Di Luigi L,Migliaccio S,Donini LM,Strollo F,Guidetti L

更新日期：2015-01-01 00:00:00

abstract：:Background. Abdominal obesity and its relative distribution are known to differ in association with metabolic characteristics and cardiorespiratory fitness. This study aimed to determine an association between fitness level and abdominal adiposity in overweight and obese adults. Methods. 228 overweight and obese indiv...

journal_title：International journal of endocrinology

authors： Kim S,Kim JY,Lee DC,Lee HS,Lee JW,Jeon JY

更新日期：2014-01-01 00:00:00

abstract：Background:The purpose of the current study is to determine PTH reference values in vitamin-D-replete Lebanese adults using 2nd and 3rd generation PTH assays and to look at the factors that affect PTH variations. Methods:Fasting PTH was measured using 2nd and 3rd generation Diasorin PTH assays in 339 vitamin-D-replete...

journal_title：International journal of endocrinology

authors： Gannagé-Yared MH,Kallas-Chémaly MN,Sleilaty G

更新日期：2020-02-21 00:00:00

abstract：:A considerable increase in endocrine abnormalities has been reported over the last few decades worldwide. A growing exposure to endocrine-disrupting chemicals (EDCs) can be one of the causes of endocrine disorders in populations, and these disorders are not only restricted to the metabolic hormone system but can also ...

journal_title：International journal of endocrinology

authors： de Oliveira M,Rodrigues BM,Olimpio RMC,Graceli JB,Gonçalves BM,Costa SMB,da Silva TM,De Sibio MT,Moretto FCF,Mathias LS,Cardoso DBM,Tilli HP,Freitas-Lima LC,Nogueira CR

更新日期：2019-04-17 00:00:00

abstract：Objective:Selenium, as an antioxidant, has been implicated in the development of autoimmune thyroiditis (AIT). Many studies showed selenium supplementation could decrease thyroid autoantibodies in patients with AIT. However, the underlying mechanisms have not been well determined. Therefore, we performed a clinical stu...

journal_title：International journal of endocrinology

authors： Tian X,Li N,Su R,Dai C,Zhang R

更新日期：2020-06-30 00:00:00

abstract：:The aim of this study is to investigate the circulating OPG levels in postmenopausal women with diabetes and prediabetes and explore the relationships between serum OPG and insulin resistance. A total of 271 unrelated Chinese postmenopausal women were recruited in this study. The subjects were divided into type 2 diab...

journal_title：International journal of endocrinology

authors： Duan P,Yang M,Wei M,Liu J,Tu P

更新日期：2017-01-01 00:00:00

abstract：:Despite 70 years of experience treating thyrotoxic patients with radioiodine not all patients are successfully treated by a single dose. Multiple factors predicting radioiodine efficacy have been reported. The aim of this study was to assess whether ethnicity was associated with radioiodine response. A retrospective r...

journal_title：International journal of endocrinology

authors： Tamatea JA,Conaglen JV,Elston MS

更新日期：2016-01-01 00:00:00

abstract：:Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. However, the effect of puerarin on the process of human osteoblasts ...

journal_title：International journal of endocrinology

authors： Liu LJ,Liu LQ,Bo T,Li SJ,Zhu Z,Cui RR,Mao DA

更新日期：2013-01-01 00:00:00

abstract：:Low birth weight is associated with reduced bone mass and density in adult life. However, effects of maternal hypoxia (MH) on offspring bone development are not known. Objective. The current study investigated the effects of fetal growth restriction induced by MH during the last half of gestation on bone structure and...

journal_title：International journal of endocrinology

authors： Lee AM,Morrison JL,Botting KJ,Shandala T,Xian CJ

更新日期：2014-01-01 00:00:00

abstract：:A retrospective review of 626 patients with multifocal papillary thyroid carcinoma (PTC) including 147 patients (23.5%) with multifocal papillary thyroid microcarcinoma (PTMC) from a total of 2,536 patients with PTC who visited the Chang Gung Medical Center in Linkou, Taiwan, was performed. A comparison of the clinica...

journal_title：International journal of endocrinology

authors： Ng SC,Kuo SF,Chen ST,Hsueh C,Huang BY,Lin JD

更新日期：2017-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is one of the primary causes of premature death and disability worldwide. We performed a systematic review and meta-analysis of the published literature regarding the trends in prevalence, awareness, treatment, and control of diabetes mellitus in mainland China. PUBMED, EMBASE, Chinese Biomedica...

journal_title：International journal of endocrinology

authors： Li MZ,Su L,Liang BY,Tan JJ,Chen Q,Long JX,Xie JJ,Wu GL,Yan Y,Guo XJ,Gu L

更新日期：2013-01-01 00:00:00

abstract：Purpose:Hyperoside, a flavonoid isolated from conventional medicinal herbs, has been demonstrated to exert a significant protective effect in diabetic nephropathy. This study aimed to determine the underlying mechanisms, by which hyperoside inhibits high glucose-(HG-) induced proliferation in mouse renal mesangial cell...

journal_title：International journal of endocrinology

authors： Zhang L,Dai Q,Hu L,Yu H,Qiu J,Zhou J,Long M,Zhou S,Zhang K

更新日期：2020-07-21 00:00:00

abstract：:The hypothalamus is an essential relay in the neural circuitry underlying energy metabolism that needs to continually adapt to changes in the energetic environment. The neuroendocrine control of food intake and energy expenditure is associated with, and likely dependent upon, hypothalamic plasticity. Severe disturbanc...

journal_title：International journal of endocrinology

authors： Stranahan AM,Martin B,Chadwick W,Park SS,Wang L,Becker KG,Woodiii WH,Zhang Y,Maudsley S

更新日期：2012-01-01 00:00:00

abstract：:Aim. To examine the relationship between plasma 25-hydroxyvitamin D (25(OH)D) levels and blood hemoglobin A1c (HbA1c) levels in diabetic patients at various stages of chronic kidney disease (CKD). Methods. We screened for data collected between 2003 and 2012. The correlation between 25(OH)D and HbA1c levels was studie...

journal_title：International journal of endocrinology

authors： Kajbaf F,Mentaverri R,Diouf M,Fournier A,Kamel S,Lalau JD

更新日期：2014-01-01 00:00:00

abstract：Background:Insulin promotes glucose consumption as the main cardiac energy source, while increasing myocardial efficiency. The short-term effects of insulin on cardiac function and its potential curative role in an acute diabetological cardiology setting remain unknown. Our study evaluated the role of acute insulin adm...

journal_title：International journal of endocrinology

authors： Daoud Naccache D,Yalonetsky S,Bar-Yoseph R

更新日期：2020-03-17 00:00:00