The Association between 25-Hydroxyvitamin D and Hemoglobin A1c Levels in Patients with Type 2 Diabetes and Stage 1-5 Chronic Kidney Disease.

Abstract:

:Aim. To examine the relationship between plasma 25-hydroxyvitamin D (25(OH)D) levels and blood hemoglobin A1c (HbA1c) levels in diabetic patients at various stages of chronic kidney disease (CKD). Methods. We screened for data collected between 2003 and 2012. The correlation between 25(OH)D and HbA1c levels was studied in patients categorized according to the severity of CKD and their vitamin D status. A multivariate linear regression model was used to determine whether 25(OH)D and HbA1c levels were independently associated after adjustment for a number of covariates (including erythrocyte metformin levels). Results. We identified 542 reports from 245 patients. The mean HbA1c value was 6.7 ± 1.0% in vitamin D sufficiency, 7.3 ± 1.5% in insufficiency, and 8.4 ± 2.0% in deficiency (P < 0.0001). There was a negative correlation between 25(OH)D and HbA1c levels for the population as a whole (r = -0.387, P < 0.0001) and in the CKD severity subgroups (r = -0.384, P < 0.0001 and r = -0.333, P < 0.0001 for CKD stages 1-3 and 4-5, resp.). In the multivariate analysis, the 25(OH)D level was the only factor associated with HbA1c (P < 0.0001). Conclusion. 25(OH)D levels were negatively correlated with HbA1c levels independently of study covariates.

journal_name

Int J Endocrinol

authors

Kajbaf F,Mentaverri R,Diouf M,Fournier A,Kamel S,Lalau JD

doi

10.1155/2014/142468

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

142468

eissn

1687-8337

issn

1687-8345

journal_volume

2014

pub_type

杂志文章
  • Potential role of sugar transporters in cancer and their relationship with anticancer therapy.

    abstract::Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. Cancer cells are well known to display an enhanced sugar uptake and consumption. In fact, sugar transporters ar...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2010/205357

    authors: Calvo MB,Figueroa A,Pulido EG,Campelo RG,Aparicio LA

    更新日期:2010-01-01 00:00:00

  • Diagnostic and Management Pathways for Pulmonary Carcinoid Tumours in the United Kingdom: Results from the National Lung Neuroendocrine Tumour Pathway Project.

    abstract::There is inconsistency among published guidelines for the optimal diagnostic and management pathways for patients with typical (TC) or atypical (AC) pulmonary carcinoid tumours. We conducted a UK-wide clinician survey to assess current practice for the diagnosis, management, and follow-up of patients with TC/AC and de...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2020/9287536

    authors: Mansoor W,Ferguson S,Ross V,Talbot D

    更新日期:2020-02-28 00:00:00

  • Comparison of Exenatide and Metformin Monotherapy in Overweight/Obese Patients with Newly Diagnosed Type 2 Diabetes.

    abstract:Aims:The present study assessed the therapeutic effect of exenatide and metformin as the initial therapy on overweight/obese patients with newly diagnosed type 2 diabetes (T2D). Methods:The prospective, nonrandomized, interventional study enrolled a total of 230 overweight or obese patients with newly diagnosed T2D wh...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2017/9401606

    authors: Liu J,Hu Y,Xu Y,Jia Y,Miao L,Wang G

    更新日期:2017-01-01 00:00:00

  • Characterization of Mineral and Bone Metabolism Biomarkers in a Chinese Consanguineous Twin Family with Primary Hypertrophic Osteoarthropathy.

    abstract:Purpose:Primary hypertrophic osteoarthropathy (PHO) is a rare, autosomal, recessive genetic disease characterized by digital clubbing, periostosis, and pachydermia. The underlying cause for the pathogenesis of this disease is a defect in prostaglandin E2 (PGE2) degradation, caused by mutations in HPGD or SLCO2A1. In th...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2020/6698878

    authors: Li N,Ma Y,Jiang Y,You L,Huang Y,Peng Y,Ding X,Zhao L

    更新日期:2020-12-03 00:00:00

  • GNPDA2 Gene Affects Adipogenesis and Alters the Transcriptome Profile of Human Adipose-Derived Mesenchymal Stem Cells.

    abstract:Background:Genome-wide association studies have found an obesity-related single-nucleotide polymorphism rs10938397 near the glucosamine-6-phosphate deaminase 2 gene (GNPDA2) encoding, an enzyme that catalyzes the deamination of the glucosamine-6-phosphate involved in the hexosamine signaling pathway, but the molecular ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2019/9145452

    authors: Wu L,Ma F,Zhao X,Zhang MX,Wu J,Mi J

    更新日期:2019-08-01 00:00:00

  • Chronic sleep disturbance impairs glucose homeostasis in rats.

    abstract::Epidemiological studies have shown an association between short or disrupted sleep and an increased risk for metabolic disorders. To assess a possible causal relationship, we examined the effects of experimental sleep disturbance on glucose regulation in Wistar rats under controlled laboratory conditions. Three groups...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2010/819414

    authors: Barf RP,Meerlo P,Scheurink AJ

    更新日期:2010-01-01 00:00:00

  • Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway.

    abstract::Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. However, the effect of puerarin on the process of human osteoblasts ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2013/786574

    authors: Liu LJ,Liu LQ,Bo T,Li SJ,Zhu Z,Cui RR,Mao DA

    更新日期:2013-01-01 00:00:00

  • The Impact of Preconceptional Serum TSH Levels between 2.5 and 4.0 mIU/L on Infertile Women Going through Their First IUI Treatment Cycle.

    abstract:Objective:To evaluate the impact of preconceptional serum TSH levels on the clinical outcomes of infertile patients undergoing their first IUI treatment cycle. Method:This was a retrospective study. Euthyroid patients undergoing the first cycle of IUI treatment from Jan 2017 to Aug 2018 were included. The patients wer...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2019/8492904

    authors: Zhang Y,Wu W,Liu Y,Wang X,Jia L

    更新日期:2019-12-18 00:00:00

  • Association among Fibrinolytic Proteins, Metabolic Syndrome Components, Insulin Secretion, and Resistance in Schoolchildren.

    abstract::We investigated the role of urokinase plasminogen activator (uPA) and its soluble receptors (suPAR) and plasminogen activator inhibitor-1 (PAI-1) in metabolic syndrome (MetS) components, insulin secretion, and resistance in schoolchildren. We enrolled 387 children, aged 10.3 ± 1.5 years, in Taipei. Anthropometry, fibr...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/170987

    authors: Chen JS,Wu CZ,Chu NF,Chang LC,Pei D,Lin YF

    更新日期:2015-01-01 00:00:00

  • The Age-Specific Association of Waist Circumference and Risk of Chronic Kidney Disease in Patients with Type 2 Diabetes Mellitus in Shandong, China.

    abstract::Objective. To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). Design. Cross-sectional evaluation of the effect of anthropometric ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/715871

    authors: Xu L,Yu W,Huang P,Li C,Li Y,Wang M,Xu Q,Wang J,Zheng C,Qu B,Zhao Y,Niu M,Wang O,Gong F

    更新日期:2015-01-01 00:00:00

  • Response to Radioiodine Therapy for Thyrotoxicosis: Disparate Outcomes for an Indigenous Population.

    abstract::Despite 70 years of experience treating thyrotoxic patients with radioiodine not all patients are successfully treated by a single dose. Multiple factors predicting radioiodine efficacy have been reported. The aim of this study was to assess whether ethnicity was associated with radioiodine response. A retrospective r...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2016/7863867

    authors: Tamatea JA,Conaglen JV,Elston MS

    更新日期:2016-01-01 00:00:00

  • Simvastatin does not affect vitamin d status, but low vitamin d levels are associated with dyslipidemia: results from a randomised, controlled trial.

    abstract::Objectives. Statin drugs act as inhibitors of the 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase enzyme early in the mevalonate pathway, thereby reducing the endogenous cholesterol synthesis. In recent studies, it has been suggested from epidemiological data that statins also may improve vitamin D status, as...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2010/957174

    authors: Rejnmark L,Vestergaard P,Heickendorff L,Mosekilde L

    更新日期:2010-01-01 00:00:00

  • Sperm proteomics: road to male fertility and contraception.

    abstract::Spermatozoa are highly specialized cells that can be easily obtained and purified. Mature spermatozoa are transcriptionally and translationally inactive and incapable of protein synthesis. In addition, spermatozoa contain relatively higher amounts of membrane proteins compared to other cells; therefore, they are very ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2013/360986

    authors: Rahman MS,Lee JS,Kwon WS,Pang MG

    更新日期:2013-01-01 00:00:00

  • Exercise for hepatic fat accumulation in type 2 diabetic subjects.

    abstract::Type 2 diabetes is characterized by frequent ectopic fat accumulation in several tissues and organs. In particular, a number of studies showed that these subjects frequently have hepatic fat accumulation, which may play a role in the metabolic abnormalities typical of diabetes and has been also linked to increased ris...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2013/309191

    authors: Bacchi E,Moghetti P

    更新日期:2013-01-01 00:00:00

  • An Evaluation of Growth Hormone and IGF-1 Responses in Neonates with Hyperinsulinaemic Hypoglycaemia.

    abstract::Background. Hyperinsulinaemic Hypoglycaemia (HH) is the most common cause of severe and persistent hypoglycemia in the neonatal period. It has been shown that the neonates with HH fail to generate adequate serum cortisol counterregulatory response to symptomatic hypoglycemia. However the role played by growth hormone ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2013/638257

    authors: Senniappan S,Hussain K

    更新日期:2013-01-01 00:00:00

  • Comorbidity between Type 2 Diabetes and Depression in the Adult Population: Directions of the Association and Its Possible Pathophysiological Mechanisms.

    abstract::Type 2 diabetes and depression are regarded as comorbid conditions, and three possible directions of the association between the diseases can underlie this observation of comorbidity. First, common etiology can increase a person's risk of both diseases; second, persons with type 2 diabetes have increased prevalence or...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2015/164760

    authors: Berge LI,Riise T

    更新日期:2015-01-01 00:00:00

  • Correlation between B-Type Natriuretic Peptide and Functional/Cognitive Parameters in Discharged Congestive Heart Failure Patients.

    abstract::The determination of B-type natriuretic peptides (BNP) may have a role in the diagnosis of heart failure (HF) or guiding HF therapy. This study investigated the role of BNP determination in a cohort of elderly patients admitted to hospital with acute decompensated HF and its correlation with main demographic, clinical...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/239136

    authors: Leto L,Testa M,Feola M

    更新日期:2015-01-01 00:00:00

  • Vitamin D Deficiency as a Predictive Factor of Transient Hypocalcemia after Total Thyroidectomy.

    abstract:Background:Total thyroidectomy (TT) is recommended in the treatment of malignant and benignant thyroid diseases, and, to date, transient hypocalcemia is the most frequent complication after the procedure. We prospectively evaluated the role of vitamin D deficiency as a predictor of postoperative hypocalcemia. Methods:...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2020/8875257

    authors: Bove A,Dei Rocini C,Di Renzo RM,Farrukh M,Palone G,Chiarini S,Staniscia T

    更新日期:2020-10-10 00:00:00

  • Corrigendum to "Chronic Glucocorticoid-Rich Milieu and Liver Dysfunction".

    abstract::[This corrects the article DOI: 10.1155/2016/7838290.]. ...

    journal_title:International journal of endocrinology

    pub_type: 已发布勘误

    doi:10.1155/2018/1239718

    authors: Villagarcía HG,Sabugo V,Castro MC,Schinella G,Castrogiovanni D,Spinedi E,Massa ML,Francini F

    更新日期:2018-10-23 00:00:00

  • Psychological status and quality of life in relation to the metabolic syndrome: Isfahan Cohort Study.

    abstract:OBJECTIVE:Current study was designed to investigate the association of metabolic syndrome (MetS) with depression, anxiety, psychological distress, and quality of life (QoL). DESIGN:Two hundred and fifteen contributors with MetS and 253 participants without MetS were randomly selected from 2151 participants of Isfahan ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2012/380902

    authors: Roohafza H,Sadeghi M,Talaei M,Pourmoghaddas Z,Sarrafzadegan N

    更新日期:2012-01-01 00:00:00

  • Osteoarticular changes in acromegaly.

    abstract::Acromegaly is caused by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-I (IGF-1) due to pituitary tumor. Other causes, such as increased growth-hormone releasing hormone (GHRH) production, ectopic GHRH production, and ectopic GH secretion, are rare. Growth hormone and IGF-1 play a...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2012/839282

    authors: Killinger Z,Kužma M,Sterančáková L,Payer J

    更新日期:2012-01-01 00:00:00

  • Experimenter Effects on Pain Reporting in Women Vary across the Menstrual Cycle.

    abstract::Background. Separate lines of research have shown that menstrual cycling and contextual factors such as the gender of research personnel influence experimental pain reporting. Objectives. This study examines how brief, procedural interactions with female and male experimenters can affect experimentally reported pain (...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2015/520719

    authors: Vigil JM,DiDomenico J,Strenth C,Coulombe P,Kruger E,Mueller AA,Guevara Beltran D,Adams I

    更新日期:2015-01-01 00:00:00

  • Immunohistochemical Study of NR2C2, BTG2, TBX19, and CDK2 Expression in 31 Paired Primary/Recurrent Nonfunctioning Pituitary Adenomas.

    abstract::This study investigated potential markers for predicting nonfunctioning pituitary adenoma (NFPA) invasion and recurrence by high-throughput tissue microarray analyses. We retrospectively studied two groups of patients: 60 nonrecurrent NFPA cases that included noninvasion and invasion subtypes and 43 recurrent cases th...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2019/5731639

    authors: Yao X,Zhang Y,Wu L,Cheng R,Li C,Qu C,Ji H

    更新日期:2019-05-16 00:00:00

  • Circulating MicroRNAs as Biomarkers of Gestational Diabetes Mellitus: Updates and Perspectives.

    abstract::Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance, with onset or first recognition during second or third trimester of gestation. It is estimated that approximately 7% of all pregnancies are complicated by GDM and that its prevalence is rising all over the world. Thus, the screen...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2018/6380463

    authors: Guarino E,Delli Poggi C,Grieco GE,Cenci V,Ceccarelli E,Crisci I,Sebastiani G,Dotta F

    更新日期:2018-04-12 00:00:00

  • Clinical Characteristics of Endogenous Cushing's Syndrome at a Medical Center in Southern Taiwan.

    abstract::From January 1987 to December 2011, over a total of 25 years, 84 patients with Cushing's syndrome (CS) were identified at a medical center in southern Taiwan. We observed a higher incidence of ACTH-independent CS (75%) than ACTH-dependent CS (25%). A higher incidence of adrenocortical adenoma (58.3%) than Cushing's di...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2013/685375

    authors: Tung SC,Wang PW,Liu RT,Chen JF,Hsieh CJ,Kuo MC,Yang JW,Lee WC,Cheng MH,Lee TC

    更新日期:2013-01-01 00:00:00

  • Islet Stellate Cells Regulate Insulin Secretion via Wnt5a in Min6 Cells.

    abstract:Background:Type 2 diabetes mellitus is a serious public health problem worldwide. Accumulating evidence has shown that β-cell dysfunction is an important mechanism underlying diabetes mellitus. The changes in the physiological state of islet stellate cells (ISCs) and the effects of these cells on β-cell dysfunction is ...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2020/4708132

    authors: Xu W,Jones PM,Geng H,Li R,Liu X,Li Y,Lv Q,Liu Y,Wang J,Wang X,Sun Z,Liang J

    更新日期:2020-02-24 00:00:00

  • Effectiveness of Coenzyme Q10 Supplementation for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.

    abstract:Objective:To evaluate the effectiveness and safety of coenzyme Q10 for patients with type 2 diabetes mellitus (T2DM). Methods:Data from randomized controlled trials were obtained to assess the effects of coenzyme Q10 versus placebo or western medicine on patients with T2DM. The study's registration number is CRD420180...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2018/6484839

    authors: Zhang SY,Yang KL,Zeng LT,Wu XH,Huang HY

    更新日期:2018-09-16 00:00:00

  • MicroRNA and Microvascular Complications of Diabetes.

    abstract::In the last decade, miRNAs have received substantial attention as potential players of diabetes microvascular complications, affecting the kidney, the retina, and the peripheral neurons. Compelling evidence indicates that abnormally expressed miRNAs have pivotal roles in key pathogenic processes of microvascular compl...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1155/2018/6890501

    authors: Barutta F,Bellini S,Mastrocola R,Bruno G,Gruden G

    更新日期:2018-03-07 00:00:00

  • Investigating the Interactive Effects of Sex Steroid Hormones and Brain-Derived Neurotrophic Factor during Adolescence on Hippocampal NMDA Receptor Expression.

    abstract::Sex steroid hormones have neuroprotective properties which may be mediated by brain-derived neurotrophic factor (BDNF). This study sought to determine the interactive effects of preadolescent hormone manipulation and BDNF heterozygosity (+/-) on hippocampal NMDA-R expression. Wild-type and BDNF+/- mice were gonadectom...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2018/7231915

    authors: McCarthny CR,Du X,Wu YC,Hill RA

    更新日期:2018-01-31 00:00:00

  • The serum level of fibroblast growth factor-23 and calcium-phosphate homeostasis in obese perimenopausal women.

    abstract::Plasma FGF-23 concentrations and its relationship with calcium-phosphate homeostasis were evaluated in 48 perimenopausal obese women and in 29 nonobese controls. Serum parathyroid hormone, 25-hydroxyvitamin D(3), CTX1, osteocalcin, total calcium, phosphorus, creatinine, and plasma intact FGF-23 concentrations were ass...

    journal_title:International journal of endocrinology

    pub_type: 杂志文章

    doi:10.1155/2011/707126

    authors: Holecki M,Chudek J,Więcek A,Titz-Bober M,Duława J

    更新日期:2011-01-01 00:00:00